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Volumn 69, Issue 1, 2014, Pages 34-40

Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives

Author keywords

Antiviral therapy; Drug susceptibility; Hplc; Metabolism

Indexed keywords

ARTEMISININ; ARTESUNATE; DIHYDROARTEMISININ;

EID: 84890405658     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt346     Document Type: Article
Times cited : (48)

References (36)
  • 1
    • 78049355534 scopus 로고    scopus 로고
    • Antiviral drug resistance of human cytomegalovirus
    • Lurain NS, Chou S. Antiviral drug resistance of human cytomegalovirus. Clin Microbiol Rev 2010; 23: 689-712.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 689-712
    • Lurain, N.S.1    Chou, S.2
  • 2
    • 77956397844 scopus 로고    scopus 로고
    • Artemisinin-derived dimers have greatly improved anti-cytomegalovirus activity compared to artemisinin monomers
    • Arav-Boger R, He R, Chiou CJ et al. Artemisinin-derived dimers have greatly improved anti-cytomegalovirus activity compared to artemisinin monomers. PLoS One 2010; 5: e10370.
    • (2010) PLoS One , vol.5
    • Arav-Boger, R.1    He, R.2    Chiou, C.J.3
  • 3
    • 80054868538 scopus 로고    scopus 로고
    • The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants
    • Chou S, Marousek G, Auerochs S et al. The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants. Antiviral Res 2011; 92: 364-8.
    • (2011) Antiviral Res , vol.92 , pp. 364-368
    • Chou, S.1    Marousek, G.2    Auerochs, S.3
  • 4
    • 0036238927 scopus 로고    scopus 로고
    • Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses
    • Efferth T, Marschall M, Wang X et al. Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses. J Mol Med (Berl) 2002; 80: 233-42.
    • (2002) J Mol Med (Berl) , vol.80 , pp. 233-242
    • Efferth, T.1    Marschall, M.2    Wang, X.3
  • 5
    • 51549118662 scopus 로고    scopus 로고
    • The antiviral activities of artemisinin and artesunate
    • Efferth T, Romero MR, Wolf DG et al. The antiviral activities of artemisinin and artesunate. Clin Infect Dis 2008; 47: 804-11.
    • (2008) Clin Infect Dis , vol.47 , pp. 804-811
    • Efferth, T.1    Romero, M.R.2    Wolf, D.G.3
  • 6
    • 31444451671 scopus 로고    scopus 로고
    • The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo
    • Kaptein SJ, Efferth T, Leis M et al. The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo. Antiviral Res 2006; 69: 60-9.
    • (2006) Antiviral Res , vol.69 , pp. 60-69
    • Kaptein, S.J.1    Efferth, T.2    Leis, M.3
  • 7
    • 78751609314 scopus 로고    scopus 로고
    • Antiviral activity of ganciclovir and artesunate towards human cytomegalovirus in astrocytoma cells
    • Schnepf N, Corvo J, Pors MJ et al. Antiviral activity of ganciclovir and artesunate towards human cytomegalovirus in astrocytoma cells. Antiviral Res 2011; 89: 186-8.
    • (2011) Antiviral Res , vol.89 , pp. 186-188
    • Schnepf, N.1    Corvo, J.2    Pors, M.J.3
  • 8
    • 0347285290 scopus 로고    scopus 로고
    • Artesunate combinations for treatment of malaria: meta-analysis
    • Adjuik M, Babiker A, Garner P et al. Artesunate combinations for treatment of malaria: meta-analysis. Lancet 2004; 363: 9-17.
    • (2004) Lancet , vol.363 , pp. 9-17
    • Adjuik, M.1    Babiker, A.2    Garner, P.3
  • 9
  • 10
    • 79951821212 scopus 로고    scopus 로고
    • Artesunate is ineffective in controlling valganciclovir-resistant cytomegalovirus infection
    • Lau PK, Woods ML, Ratanjee SK et al. Artesunate is ineffective in controlling valganciclovir-resistant cytomegalovirus infection. Clin Infect Dis 2011; 52: 279.
    • (2011) Clin Infect Dis , vol.52 , pp. 279
    • Lau, P.K.1    Woods, M.L.2    Ratanjee, S.K.3
  • 11
    • 42549168601 scopus 로고    scopus 로고
    • Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
    • Shapira MY, Resnick IB, Chou S et al. Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation. Clin Infect Dis 2008; 46: 1455-7.
    • (2008) Clin Infect Dis , vol.46 , pp. 1455-1457
    • Shapira, M.Y.1    Resnick, I.B.2    Chou, S.3
  • 12
    • 80052673399 scopus 로고    scopus 로고
    • Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration
    • Morris CA, Duparc S, Borghini-Fuhrer I et al. Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration. Malar J 2011; 10: 263.
    • (2011) Malar J , vol.10 , pp. 263
    • Morris, C.A.1    Duparc, S.2    Borghini-Fuhrer, I.3
  • 13
    • 0033554788 scopus 로고    scopus 로고
    • Current status of artemisinin and its derivatives as antimalarial drugs
    • Dhingra V, Vishweshwar Rao K, Lakshmi Narasu M. Current status of artemisinin and its derivatives as antimalarial drugs. Life Sci 2000; 66: 279-300.
    • (2000) Life Sci , vol.66 , pp. 279-300
    • Dhingra, V.1    Vishweshwar Rao, K.2    Lakshmi Narasu, M.3
  • 14
    • 77954781884 scopus 로고    scopus 로고
    • The pharmaceutical death-ride of dihydroartemisinin
    • Jansen FH. The pharmaceutical death-ride of dihydroartemisinin. Malar J 2010; 9: 212.
    • (2010) Malar J , vol.9 , pp. 212
    • Jansen, F.H.1
  • 15
    • 0021948029 scopus 로고
    • Qinghaosu (artemisinin): an antimalarial drug fromChina
    • KlaymanDL. Qinghaosu (artemisinin): an antimalarial drug fromChina. Science 1985; 228: 1049-55.
    • (1985) Science , vol.228 , pp. 1049-1055
    • Klayman, D.L.1
  • 16
    • 80053976628 scopus 로고    scopus 로고
    • The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
    • Tu Y. The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine. Nat Med 2011; 17: 1217-20.
    • (2011) Nat Med , vol.17 , pp. 1217-1220
    • Tu, Y.1
  • 17
    • 9144247114 scopus 로고    scopus 로고
    • Artemisinins: activities and actions
    • Haynes RK, Krishna S. Artemisinins: activities and actions. Microbes Infect 2004; 6: 1339-46.
    • (2004) Microbes Infect , vol.6 , pp. 1339-1346
    • Haynes, R.K.1    Krishna, S.2
  • 18
    • 0037021405 scopus 로고    scopus 로고
    • Artemisinin: mechanisms of action, resistance and toxicity
    • Meshnick SR. Artemisinin: mechanisms of action, resistance and toxicity. Int J Parasitol 2002; 32: 1655-60.
    • (2002) Int J Parasitol , vol.32 , pp. 1655-1660
    • Meshnick, S.R.1
  • 19
    • 0027197112 scopus 로고
    • Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu)
    • Meshnick SR, Yang YZ, Lima V et al. Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu). Antimicrob Agents Chemother 1993; 37: 1108-14.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1108-1114
    • Meshnick, S.R.1    Yang, Y.Z.2    Lima, V.3
  • 20
    • 33644672627 scopus 로고    scopus 로고
    • Artesunate in the treatment of metastatic uveal melanoma-first experiences
    • Berger TG, Dieckmann D, Efferth T et al. Artesunate in the treatment of metastatic uveal melanoma-first experiences. Oncol Rep 2005; 14: 1599-603.
    • (2005) Oncol Rep , vol.14 , pp. 1599-1603
    • Berger, T.G.1    Dieckmann, D.2    Efferth, T.3
  • 21
    • 84855554316 scopus 로고    scopus 로고
    • Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug
    • Crespo-Ortiz MP, Wei MQ. Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug. J Biomed Biotechnol 2012; 2012: 247597.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 247597
    • Crespo-Ortiz, M.P.1    Wei, M.Q.2
  • 22
    • 0035315838 scopus 로고    scopus 로고
    • The anti-malarial artesunate is also active against cancer
    • Efferth T, Dunstan H, Sauerbrey A et al. The anti-malarial artesunate is also active against cancer. Int J Oncol 2001; 18: 767-73.
    • (2001) Int J Oncol , vol.18 , pp. 767-773
    • Efferth, T.1    Dunstan, H.2    Sauerbrey, A.3
  • 23
    • 33750858216 scopus 로고    scopus 로고
    • Case report of a pituitary macroadenoma treated with artemether
    • Singh NP, Panwar VK. Case report of a pituitary macroadenoma treated with artemether. Integr Cancer Ther 2006; 5: 391-4.
    • (2006) Integr Cancer Ther , vol.5 , pp. 391-394
    • Singh, N.P.1    Panwar, V.K.2
  • 24
    • 0020216439 scopus 로고
    • The immunologic and anti. viral effect of qinghaosu
    • Qian RS, Li ZL, Yu JL et al. The immunologic and antiviral effect of qinghaosu. J Trad Chin Med 1982; 2: 271-6.
    • (1982) J Trad Chin Med , vol.2 , pp. 271-276
    • Qian, R.S.1    Li, Z.L.2    Yu, J.L.3
  • 25
    • 42249110559 scopus 로고    scopus 로고
    • Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency
    • Stinski MF, Isomura H. Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency. Med Microbiol Immunol 2008; 197: 223-31.
    • (2008) Med Microbiol Immunol , vol.197 , pp. 223-231
    • Stinski, M.F.1    Isomura, H.2
  • 26
    • 84862564807 scopus 로고    scopus 로고
    • Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication
    • He R, Park K, CaiHet al. Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication. Antimicrob Agents Chemother 2012; 56: 3508-15.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3508-3515
    • He, R.1    Park, K.2    Cai, H.3
  • 27
    • 80052337277 scopus 로고    scopus 로고
    • An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities
    • He R, Mott BT, Rosenthal AS et al. An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities. PLoS One 2011; 6: e24334.
    • (2011) PLoS One , vol.6
    • He, R.1    Mott, B.T.2    Rosenthal, A.S.3
  • 28
    • 0035172395 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria
    • Davis TM, Phuong HL, Ilett KF et al. Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria. Antimicrob Agents Chemother 2001; 45: 181-6.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 181-186
    • Davis, T.M.1    Phuong, H.L.2    Ilett, K.F.3
  • 29
    • 65549117770 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of endoperoxide antimalarials
    • Gautam A, Ahmed T, Batra V et al. Pharmacokinetics and pharmacodynamics of endoperoxide antimalarials. Curr Drug Metab 2009; 10: 289-306.
    • (2009) Curr Drug Metab , vol.10 , pp. 289-306
    • Gautam, A.1    Ahmed, T.2    Batra, V.3
  • 30
    • 84864414922 scopus 로고    scopus 로고
    • Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: phase 1b study
    • Miller RS, Li Q, Cantilena LR et al. Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: phase 1b study. Malar J 2012; 11: 255.
    • (2012) Malar J , vol.11 , pp. 255
    • Miller, R.S.1    Li, Q.2    Cantilena, L.R.3
  • 31
    • 57149122043 scopus 로고    scopus 로고
    • Rapid determination of antiviral drug susceptibility of human cytomegalovirus by real-time PCR
    • Schnepf N, Boiteau N, Petit F et al. Rapid determination of antiviral drug susceptibility of human cytomegalovirus by real-time PCR. Antiviral Res 2009; 81: 64-7.
    • (2009) Antiviral Res , vol.81 , pp. 64-67
    • Schnepf, N.1    Boiteau, N.2    Petit, F.3
  • 32
    • 0033779090 scopus 로고    scopus 로고
    • Pk-fit: a pharmacokinetic/pharmacodynamic and statistical data analysis software
    • Farenc C, Fabreguette JR, Bressolle F. Pk-fit: a pharmacokinetic/pharmacodynamic and statistical data analysis software. Comput Biomed Res 2000; 33: 315-29.
    • (2000) Comput Biomed Res , vol.33 , pp. 315-329
    • Farenc, C.1    Fabreguette, J.R.2    Bressolle, F.3
  • 33
    • 0029891746 scopus 로고    scopus 로고
    • Transport of artemisinin and sodium artesunate in Caco-2 intestinal epithelial cells
    • Augustijns P, D'Hulst A, Van Daele J et al. Transport of artemisinin and sodium artesunate in Caco-2 intestinal epithelial cells. J Pharm Sci 1996; 85: 577-9.
    • (1996) J Pharm Sci , vol.85 , pp. 577-579
    • Augustijns, P.1    D'Hulst, A.2    Van Daele, J.3
  • 34
    • 79955086441 scopus 로고    scopus 로고
    • Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation
    • Wolf DG, Shimoni A, Resnick IB et al. Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation. Antiviral Res 2011; 90: 183-6.
    • (2011) Antiviral Res , vol.90 , pp. 183-186
    • Wolf, D.G.1    Shimoni, A.2    Resnick, I.B.3
  • 35
    • 77951436519 scopus 로고    scopus 로고
    • Toxicity of the antimalarial artemisinin and its derivatives
    • Efferth T, Kaina B. Toxicity of the antimalarial artemisinin and its derivatives. Crit Rev Toxicol 2010; 40: 405-21.
    • (2010) Crit Rev Toxicol , vol.40 , pp. 405-421
    • Efferth, T.1    Kaina, B.2
  • 36
    • 1642482269 scopus 로고    scopus 로고
    • Artemisinin derivatives: Toxic for laboratory animals, safe for humans?
    • Gordi T, Lepist EI. Artemisinin derivatives: toxic for laboratory animals, safe for humans? Toxicol Lett 2004; 147: 99-107.
    • (2004) Toxicol Lett , vol.147 , pp. 99-107
    • Gordi, T.1    Lepist, E.I.2


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