Demeclocycline attenuates hyponatremia by reducing aquaporin-2 expression in the renal inner medulla

American Journal of Physiology - Renal Physiology

Volumn 305, Issue 12, 2013, Pages

  Kortenoeven, Marleen L A ^a,b   Sinke, Anne P ^a   Hadrup, Niels ^a,c   Trimpert, Christiane ^a   Wetzels, Jack F M ^a   Fenton, Robert A ^b   Deen, Peter M T ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b AARHUS UNIVERSITY   (Denmark)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Aquaporin 2; Collecting duct; Demeclocycline; Syndrome of inappropriate antidiuretic hormone secretion; Vasopressin

Indexed keywords

ADENYLATE CYCLASE; AQUAPORIN 2; CYCLIC AMP; DEMECLOCYCLINE; DESMOPRESSIN; VASOPRESSIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENETIC TRANSCRIPTION; HYPONATREMIA; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URINE OSMOLALITY; URINE VOLUME;

AQUAPORIN 2; COLLECTING DUCT; DEMECLOCYCLINE; SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION; VASOPRESSIN;

ADENYLATE CYCLASE; ANIMALS; ANTI-BACTERIAL AGENTS; AQUAPORIN 2; CELLS, CULTURED; CYCLIC AMP; DEAMINO ARGININE VASOPRESSIN; DEMECLOCYCLINE; DISEASE MODELS, ANIMAL; HYPONATREMIA; INAPPROPRIATE ADH SYNDROME; KIDNEY MEDULLA; MALE; MICE; MINOCYCLINE; RATS; RATS, WISTAR; VASOPRESSINS;

EID: 84890404335     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00723.2012     Document Type: Article

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