A transient α-helical molecular recognition element in the disordered N-terminus of the Sgs1 helicase is critical for chromosome stability and binding of Top3/Rmi1

Nucleic Acids Research

Volumn 41, Issue 22, 2013, Pages 10215-10227

  Kennedy, Jessica A ^a   Daughdrill, Gary W ^a   Schmidt, Kristina H ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; HELICASE; PROLINE; PROTEIN TOP3; SGS1 HELICASE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; ENZYME BINDING; GENE REARRANGEMENT; IN VITRO STUDY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

CHROMOSOMAL INSTABILITY; DNA-BINDING PROTEINS; INTRINSICALLY DISORDERED PROTEINS; MUTAGENESIS; PROLINE; PROTEIN STRUCTURE, SECONDARY; RECQ HELICASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84890385201     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt817     Document Type: Article

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