Adjunctive input to the nuclear thyroid hormone receptor from the cell surface receptor for the hormone

Thyroid

Volumn 23, Issue 12, 2013, Pages 1503-1509

  Davis, Paul J ^a,b   Lin, Hung Yun ^c   Tang, Heng Yuan ^a   Davis, Faith B ^a   Mousa, Shaker A ^a  

^a ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

^c Graduate Institute of Cancer Biology and Drug Discovery   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CELL SURFACE RECEPTOR; LIOTHYRONINE; NUCLEAR PROTEIN; NUCLEAR RECEPTOR COACTIVATOR; NUCLEAR RECEPTOR COREPRESSOR; SERINE; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA1; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ACETYLATION; CELL MEMBRANE; CELL MIGRATION; GENETIC TRANSCRIPTION; GENOMICS; HORMONE TRANSPORT; PHOSPHORYLATION; PRIORITY JOURNAL; REVIEW;

CELL NUCLEUS; HUMANS; PROTEIN TRANSPORT; RECEPTORS, CELL SURFACE; RECEPTORS, THYROID HORMONE; SIGNAL TRANSDUCTION; THYROID HORMONES;

EID: 84890381490     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2013.0280     Document Type: Review

References (61)

1. Cheng S-Y, Leonard JL, Davis PJ 2010 Molecular aspects of thyroid hormone actions. Endocr Rev 31: 139-170.
2. Liu Y, Xia X, Fondell JD, Yen PM 2006 Thyroid hormoneregulated target genes have distinct patterns of coactivator recruitment and histone acetylation. Mol Endocrinol 20: 483-490. (Pubitemid 43291203)
3. Brent GA 2012 Mechanisms of thyroid hormone action. J Clin Invest 122: 3035-3043.
4. Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, Meltzer PS 2003 Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep 4: 581-587. (Pubitemid 36939949)
5. Visser WE, Heemstra KA, Swagemakers SMA, Ozgur Z, Corssmit EP, Burggraaf J, van Ijcken WFJ, van der Spek PJ, Smit JWA, Visser TJ 2009 Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts. J Clin Endocrinol Metab 94: 3487-3496.
6. Bergh JJ, Lin H-Y, Lansing L, Mohamed SN, Davis FB, Mousa S, Davis PJ 2005 Integrin alphavbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology 146: 2864-2871. (Pubitemid 41002793)
7. Cody V, Davis PJ, Davis FB 2007 Molecular modeling of the thyroid hormone interactions with alpha v beta3 integrin. Steroids 72: 165-170. (Pubitemid 46273491)
8. Davis PJ, Davis FB, Mousa SA, Luidens MK, Lin HY 2011 Membrane receptor for thyroid hormone: physiologic and pharmacologic implications. Annu Rev Pharmacol Toxicol 51: 99-115.
9. Lin HY, Sun M, Tang HY, Luidens MK, Mousa SA, Incerpi S, Drusano GL, Davis FB, Davis PJ 2009 L-Thyroxine vs. 3,5, 3¢-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Am J Physiol Cell Physiol 296:C9809-C9991.
10. Davis PJ, Shih A, Lin HY, Martino LJ, Davis FB 2000 Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR. J Biol Chem 275: 38032-38039. (Pubitemid 32004926)
11. Lin HY, Zhang S, West BL, Tang HY, Passaretti T, Davis FB, Davis PJ 2003 Identification of the putative MAP kinase docking site in the thyroid hormone receptor-beta1 DNA binding domain: functional consequences of mutations at the docking site. Biochemistry 42: 7571-7579. (Pubitemid 36735834)
12. Lin HY, Hopkins R, Cao HJ, Tang HY, Alexander C, Davis FB, Davis PJ 2005 Acetylation of nuclear hormone receptor superfamily members: thyroid hormone causes acetylation of its own receptor by a mitogen-activated protein kinasedependent mechanism. Steroids 70: 444-449. (Pubitemid 40626763)
13. Maruvada P, Baumann CT, Hager GL, Yen PM 2003 Dynamic shuttling and intranuclear mobility of nuclear hormone receptors. J Biol Chem 278: 12425-12432. (Pubitemid 36800229)
14. Zhu X-G, Hanover JA, Hager GL, Cheng S-Y 1998 Hormoneinduced translocation of thyroid hormone receptors in living cells visualized using a receptor green fluorescent protein chimera. J Biol Chem 273: 27058-27063. (Pubitemid 28500409)
15. Cao HJ, Lin HY, Luidens MK, Davis FB, Davis PJ 2009 Cytoplasm- to-nucleus shuttling of thyroid hormone receptorbeta1 (TRbeta1) is directed from a plasma membrane integrin receptor by thyroid hormone. Endocr Res 34: 31-42.
16. Lin HY, Su YF, Hsieh MT, Lin S, Meng R, London D, Lin C, Tang HY, Hwang J, Davis FB, Mousa SA, Davis PJ 2013 Nuclear monomeric integrin av in cancer cells is a coactivator regulated by thyroid hormone. FASEB J 27:3209- 3216.
17. Lin HY, Cody V, Davis FB, Hercbergs AA, Luidens MK, Mousa SA, Davis PJ 2011 Identification and functions of the plasma membrane receptor for thyroid hormone analogues. Discov Med 11: 337-347.
18. Luidens MK, Mousa SA, Davis FB, Lin HY, Davis PJ 2010 Thyroid hormone-induced angiogenesis. Vasc Pharmacol 52: 142-145.
19. Davis PJ, Davis FB, Lin HY 2008 Promotion by thyroid hormone of cytoplasm-to-nucleus shuttling of thyroid hormone receptors. Steroids 73: 1013-1017.
20. Tang HY, Lin HY, Zhang S, Davis FB, Davis PJ 2004 Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor. Endocrinology 145: 3265-3272. (Pubitemid 38829999)
21. Lin HY, Martino LJ, Wilcox BD, Davis FB, Gordinier JK, Davis PJ 1998 Potentiation by thyroid hormone of human IFN-gamma-induced HLA-DR expression. J Immunol 161: 843-849. (Pubitemid 28323549)
22. Lin HY, Shih A, Davis FB, Davis PJ 1999 Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. Biochem J 338: 427-432.
23. Lossner D, Abou-Ajram C, Benge A, Reuning U 2008 Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells. Int J Biochem Cell Biol 40: 2746-2761.
24. Kim DS, Jeon OH, Lee HD, Yoo KH, Kim DS 2008 Integrin alphavbeta3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line. Biochem Biophys Res Commun 377: 479-483.
25. Reuning U 2011 Integrin avb3 promotes vitronectin gene expression in human ovarian cancer cells by implicating rel transcription factors. J Cell Biochem 112: 1909-1919.
26. Roth P, Silginer M, Goodman SL, Hasenbach K, Thies S, Murer G, Schrami P, Tabatabai G, Moch H, Tritschler I, Weller M 2013 Integrin control of the transforming growth factor-b pathway in glioblastoma. Brain 136: 564-576.
27. Lossner D, Abou-AjramC, Benge A, AumercierM, SchmittM, Reuning U 2009 Integrin alphavbeta3 upregulates integrinlinked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription. J Cell Physiol 220: 367-375.
28. Glinskii AB, Glinsky GV, Lin HY, Tang HY, Sun M, Davis FB, Luidens MK, Mousa SA, Hercbergs AH, Davis PJ 2009 Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac). Cell Cycle 8: 3554-3562.
29. Davis FB, Mousa SA, O'Connor L, Mohamed S, Lin HY, Cao HJ, Davis PJ 2004 Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circ Res 94: 1500-1506. (Pubitemid 38780323)
30. Yalcin M, Dyskin E, Lansing L, Bharali DJ, Mousa SS, Bridoux A, Hercbergs AH, Lin HY, Davis FB, Glinsky GV, Glinskii AB, Ma J, Davis PJ, Mousa SA 2010 Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid. J Clin Endocrinol Metab 95: 1972-1980.
31. Beber EH, Capelo LP, Fonseca TL, Costa CC, Lotfi CF, Scanlan TS, Gouvela CH 2009 The thyroid hormone receptor (TR) beta-selective agonist GC-1 inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast-like cells. Calcif Tissue Int 84: 324-333.
32. D'Arrezzo S, Incerpi S, Davis FB, Acconcia F, Marino M, Farias RN, Davis PJ 2004 Rapid nongenomic effects of 3, 5, 3¢-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways. Endocrinology 145: 5694-5703. (Pubitemid 39564612)
33. Plow EF, Haas TA, Zhang L, Loftus J, Smith JW 2000 Ligand binding to integrins. J Biol Chem 275: 21785-21788. (Pubitemid 30621742)
34. Campbell ID, Humphries MJ 2011 Integrin structure, activation, and interactions. Cold Spring Harb Perspect Biol 3: pii: a004994.
35. Huttenlocher A, Horwitz AR 2011 Integrins in cell migration. Cold Spring Harb Perspect Biol 3:a005074.
36. Somananth PR, Ciocca A, Byzova TV 2009 Integrin and growth factor receptor alliance in angiogenesis. Cell Biochem Biophys 53: 53-64.
37. Eliceiri BP 2001 Integrin and growth factor receptor crosstalk. Circ Res 89: 1104-1110. (Pubitemid 34627867)
38. Streuli CH, Akhtar N 2009 Signal co-operation between integrins and other receptor systems. Biochem J 418: 491-506.
39. Pinto M, Soares P, Ribatti 2011 Thyroid hormone as a regulator of tumor induced angiogenesis. Cancer Lett 301: 119-126.
40. Mousa SA, Bergh JJ, Dier E, Rebbaa A, O'Conno LJ, Yalcin M, Aljada A, Dyskin E, Davis FB, Lin HY, Davis PJ 2008 Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor. Angiogenesis 11: 183-190.
41. Lin HY, Lansing L, Merillon J-M, Davis FB, Tang HY, Shih A, Vitrac X, Krisa S, Keating T, Cao HJ, Bergh J, Quackenbush S, Davis PJ 2006 Integrin alphavbeta3 contains a receptor site for resveratrol. FASEB J 20: 1742-1744.
42. Lin HY, Sun M, Lin C, Tang HY, London D, Shih A, Davis FB, Davis PJ 2009 Androgen-induced human breast cancer cell proliferation is mediated by discrete mechanisms in estrogen receptor-alpha-positive and-negative breast cancer cells. J Steroid Biochem Mol Biol 113: 182-188.
43. Capmany G, Mart M, Santalo J, Bolton VN 1998 Distribution of a3, a5 and av integrin subunits in mature and immature oocytes. Mol Hum Reprod 10: 951-956.
44. Sato T, Konishi K, Maeda K, Yabushita K, Miwa A 2003 Integrin alpha v, c-erbB2 and DNA ploidy in lung metastases from colorectal cancer. Hepatogastroenterology 50: 27-30. (Pubitemid 36182929)
45. Ichikawa K, DeGroot LJ, Refetoff S, Horwitz AL, Pollak ER 1986 Nuclear thyroid hormone receptors in cultured human fibroblasts: improved method of isolation, partial characterization, and interaction with chromatin. Metabolism 35: 861-868. (Pubitemid 16025551)
46. Barlow JW, DeNayer P 1988 Characterization of thyroid hormone receptors in human IM-9 lymphocytes. Acta Endocrinol (Copenh) 117: 327-332. (Pubitemid 18066385)
47. Achitaka Y, Maruo M, Takeuchi Y, Nakayama H, Mochizuki M 1988 3,5,3¢-triiodo-L-thyronine binding sites in nuclei of human trophoblastic cells. Endocrinol Jpn 35: 197-206. (Pubitemid 19006047)
48. Ishikawa K, DeGroot LJ 1987 Purification and characterization of rat liver nuclear thyroid hormone receptors. Proc Natl Acad Sci USA 84: 3420-3424.
49. Giguere A, Lehoux JG, Gallo-Payet N, Bellabarba D 1992 3,5,3¢-triiodo-L-thyronine binding sites in synaptosomes from brain of chick embryo. Properties and ontogeny. Brain Res Dev Brain Res 66: 221-227.
50. Kawaguchi H, Pilbeam CC, Woodiel FN, Raisz LG 1994 Comparison of the effects of 3,5,3¢-triiodothyroacetic acid and triiodothyronine on bone resorption in cultured fetal rat long bones and neonatal mouse calvariae. J Bone Miner Res 9: 247-253.
51. Shih A, Zhang S, Cao HJ, Tang HY, Davis FB, Davis PJ, Lin HY 2004 Disparate effects of thyroid hormone on actions of epidermal growth factor and transforming growth factor-a are mediated by 3¢,5¢-cyclic adenosine 5¢-monophosphatedependent protein kinase II. Endocrinology 145: 1708-1717. (Pubitemid 38402379)
52. Davis F, Mousa SA, O'Connor L, Mohamed S, Lin HY, Cao HJ, Davis PJ 2004 Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circ Res 94: 1500-1506. (Pubitemid 38780323)
53. SS Mousa, Davis FB, Davis PJ, Mousa SA 2010 Human platelet aggregation and degranulation is induced in vitro by L-thyroxine, but not by 3,5,3¢-triiodo-L-thyronine or diiodothyropropionic acid (DITPA). Clin Appl Thromb Hemost 16: 288-293.
54. Lin HY, Landersdorfer CB, London D, Meng R, Lim CU, Lin C, Lin S, Tang HY, Brown D, Van Scoy B, Kulawy R, Queimado L, Drusano GL, Louie A, Davis FB, Mousa SA, Davis PJ 2011 Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system. PLoS Comput Biol 7:e1001073.
55. Lin HY, Davis FB, Gordinier JK, Martino LJ, Davis PJ 1999 Thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells. Am J Physiol 276:C1014-C1024. (Pubitemid 29244654)
56. Shattil SJ, Newman PJ 2004 Integrins: dynamic scaffolds for adhesion and signaling in platelets. Blood 104: 1606-1615. (Pubitemid 39202265)
57. Arnaout MA, Mahalingham B, Xiong JP 2005 Integrin structure, allostery, and bidirectional signaling. Annu Rev Cell Dev Biol 21: 381-410. (Pubitemid 41740640)
58. Morgan MR, Byron A, Humphries MJ, Bass MD 2009 Giving off mixed signals - distinct functions of alpha6beta1 and alphavbeta3 integrins in regulating cell behaviour. IUBMB Life 61: 731-738.
59. Amazit L, Alj Y, Chauchereau A, Loosfelt H, Pichon C, Pantel J, Foulon-Guinchard E, Leclerc P, Milgrom E, Guiochon- Mantel A 1999 Subcellular localization and mechanisms of nucleocytoplasmic trafficking of steroid receptor coactivator-1. J Biol Chem 278: 32195-32203.
60. Chen Y, Chen PL, Chen CF, Sharp D, Lee WH 2003 Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi apparatus to the nucleus. Proc Natl Acad Sci USA 96: 4443-4448. (Pubitemid 29190355)
61. Lin HY, Tang HY, Davis FB, Mousa SA, Incerpi S, Luidens MK, Meng R, Davis PJ 2012 Nongenomic regulation by thyroid hormone of plasma membrane ion and small molecule pumps. Discov Med 76: 199-206.