Therapeutic potentials of naringin on polymethylmethacrylate induced osteoclastogenesis and osteolysis, in vitro and in vivo assessments

Drug Design, Development and Therapy

Volumn 8, Issue , 2013, Pages 1-11

  Li, Nianhu ^a,b   Xu, Zhanwang ^b   Wooley, Paul H ^a,c   Zhang, Jianxin ^b   Yang, Shang You ^a,c  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE WICHITA   (United States)

^b SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Orthopaedic Research Institute Incorporated   (United States)

Author keywords

Aseptic loosening; Naringin; Osteoclastogenesis; Periprosthetic osteolysis

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; AURANTIIN; CATHEPSIN K; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; ACID PHOSPHATASE; CALCIUM; FLAVANONE DERIVATIVE; ISOENZYME; POLY(METHYL METHACRYLATE); TARTRATE-RESISTANT ACID PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE ATROPHY; BONE MASS; CALCIUM TRANSPORT; CATHEPSIN K GENE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LOW DRUG DOSE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B GENE; TRAP GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BONE DEVELOPMENT; CELL CULTURE; DRUG EFFECTS; METABOLISM; OSTEOCLAST; OSTEOLYSIS; PHYSIOLOGY; PREVENTION AND CONTROL; TOXICITY;

ACID PHOSPHATASE; ANIMALS; BONE RESORPTION; CALCIUM; CELLS, CULTURED; FEMALE; FLAVANONES; ISOENZYMES; MICE; MICE, INBRED BALB C; OSTEOCLASTS; OSTEOGENESIS; OSTEOLYSIS; POLYMETHYL METHACRYLATE;

EID: 84890355530     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S52714     Document Type: Article

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