Regulation of cellular metabolism: Programming and maintaining metabolic homeostasis

Journal of Applied Physiology

Volumn 115, Issue 11, 2013, Pages 1583-1588

  Wilson, David F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Homeostasis; Metabolism; Mitochondria; Oxygen; Regulation

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; OXYGEN;

ARTICLE; CELLS; ENERGY METABOLISM; HOMEOSTASIS; HUMAN; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; REGULATORY MECHANISM;

HOMEOSTASIS; METABOLISM; MITOCHONDRIA; OXYGEN; REGULATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CELLS; ENERGY METABOLISM; HOMEOSTASIS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION;

EID: 84890335253     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00894.2013     Document Type: Article

References (50)

1. Bailey SJ, Wilkerson DP, Dimenna FJ, Jones AM. Influence of repeated sprint training on pulmonary O2 uptake and muscle deoxygenation kinetics in humans. J Appl Physiol 106: 1875-1887, 2009.
2. Bartholomew GA, Casey TM. Oxygen consumption of moths during rest, pre-flight warm-up, and flight in relation to body size and wing morphology. J Exp Biol 76: 11-25, 1978.
3. Baumgärtl H, Zimelka W, Lübbers D. Evaluation of PO2 profiles to describe the oxygen pressure field within the tissue. Comp Biochem Physiol A 132: 75-85, 2002.
4. Beis IE, Newsholme EC. The contents of adenine nucleotides, phosphagens and some glycolytic intermediates in resting muscles from vertebrates and invertebrates. Biochem J 152: 23-32, 1975.
5. Butterfield NJ. Macroevolution and macroecology through deep time. Palaeontology 50: 41-55, 2007.
6. Bylund AC, Hammarsten J, Holm J, Schersten T. Enzyme activities in skeletal muscle from patients with peripheral arterial insufficiency. Eur J Clin Invest 6: 425-429, 1976.
7. Carling D, Mayer FV, Sanders MJ, Gamblin SJ. AMP-activated protein kinase: nature's energy sensor. Nat Chem Biol 7: 512-518, 2011.
8. Casey TM, May ML, Morgan KR. Flight energetics of euglossine bees in relation to morphology and wing stroke frequency. J Exp Biol 116: 271-289, 1985.
9. Erecinska M, Wilson DF. Regulation of cellular energy metabolism. J Membr Biol 70: 1-14, 1982.
10. Evans AM, Mustard KJW, Wyatt CN, Peers C, Dipp M, Kumar P, Kinnear NP, Hardie DG. Does AMP activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? J Biol Chem 280: 41504-41511, 2005.
11. Fernández MJ, Dudley R, Bozinovic F. Comparative energetics of the giant hummingbird (Patagonagigas). Physiol Biochem Zool 84: 333-340, 2011.
12. Golding EM, Golding RM. Interpretation of 31P MRS spectra in determining intracellular free magnesium and potassium ion concentrations. Magn Reson Med 33: 467-474, 1995.
13. Golub AS, Pittman RN. Bang-bang model for regulation of local blood flow. Microcirculation 20: 455-483, 2013.
14. Golub AS, Pittman RN. Oxygen dependence of respiration in rat spinotrapezius muscle in situ. Am J Physiol Heart Circ Physiol 303: H47-H56, 2012.
15. Hardie DG, Ross FA, Hawley SA. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13: 251-261, 2012.
16. Harrison DK, Kessler M, Knauf SK. Regulation of capillary blood flow and oxygen supply in skeletal muscle in dogs during hypoxaemia. J Physiol 420: 431-446, 1990.
17. Herrero-Mendez A, Almeida A, Fernández E, Maestre C, Moncada S, Bolaños JP. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/CCdh1. Nat Cell Biol 11: 747-754, 2009.
18. Holloszy JO, Booth FW. Biochemical adaptation to endurance exercise in muscle. Annu Rev Physiol 38: 273-291, 1976.
19. Holloszy JO, Coyle EF. Adaptations of skeletal muscle to endurance exercise and their consequences. J Appl Physiol 56: 831-838, 1984.
20. Holm J, Bjorntorp P, Schersten T. Metabolic activity in human skeletal muscle. Effect of peripheral arterial insufficiency. Eur J Clin Invest 2: 321-325, 1972.
21. Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1: 15-25, 2005.
22. Kemp GJ, Meyerspeer M, Moser E. Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review. NMR Biomed 20: 555-565, 2007.
23. Kemp GJ, Taylor DJ, Radda GK. Control of phosphocreatine resynthesis during recovery from exercise in human skeletal muscle. NMR Biomed 6: 66-72, 1993.
24. Koch CJ. Measurement of absolute oxygen levels in cells and tissue using oxygen sensors and 2-nitroimidazole EF5. Methods Enzymol 352: 3-31, 2002.
25. Krustrup P, Jones AM, Wilkerson DP, Calbet JA, Bangsbo J. Muscular and pulmonary O2 uptake kinetics during moderate-and highintensity sub-maximal knee-extensor exercise in humans. J Physiol 587: 1843-1856, 2009.
26. Lawson JW, Veech RL. Effects of pH and free Mg2+ on the Keq of the creatine kinase reaction and other phosphate hydrolysis and phosphate transfer reactions. J Biol Chem 254: 6528-6537, 1979.
27. Long YC, Zierath Jr. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest 116: 1776-1783, 2006.
28. Lundgren F, Dahllof AG, Schersten T, Bylund-Fellenius A-C. Muscle enzyme adaptations with peripheral arterial insufficiency: spontaneous adaptation, effect of different treatments and consequences on walking performance. Clin Sci (Colch) 77: 485-493, 1989.
29. Mihaylova MM, Shaw RJ. The AMPK signaling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 13: 1016-1023, 2011.
30. Nuutinen EM, Nishiki K, Erecinska M, Wilson DF. Role of mitochondrial oxidative phosphorylation in regulation of coronary blood flow. Am J Physiol Heart Circ Physiol 243: H159-H169, 1982.
31. Richardson RS, Poole DC, Knight DR, Kurdak SS, Hogan MC, Grassi B, Johnson EC, Kendrick B, Erickson BK, Wagner PD. High muscle blood flow in man: is maximal O2 extraction compromised? J Appl Physiol 75: 1911-1916, 1993.
32. Rumsey WL, Wilson DF. Tissue capacity for mitochondrial oxidative phosphorylation and its adaptation to stress. Handbook of Physiology, Environmental Physiology. Compr Physiol 1095-1113, first published in print 1996; 2011.
33. Salmons S, Henriksson J. The adaptive response of skeletal muscle to increased use. Muscle Nerve 4: 94-105, 1981.
34. Saltin B, Gollnick PD. Skeletal muscle adaptability: significance for metabolism and performance. Compr Physiol 555-631, 2011.
35. Saltin B, Rådegran G, Koskolou MD, Roach RC. Skeletal muscle blood flow in humans and its regulation during exercise. Acta Physiol Scand 162: 421-436, 1998.
36. Solé RV, Fernández P, Kauffman SA. Adaptive walks in a gene network model of morphogenesis: insights into the Cambrian explosion. Int J Dev Biol 47: 685-693, 2003.
37. Veech RL, Lawson JW, Cornell NW, Krebs HA. Cytosolic phosphorylation potential. J Biol Chem 254: 6538-6547, 1979.
38. Wallace DC. Mitochondria and cancer. Nat Rev Cancer 12: 685-698, 2012.
39. Warburg O, Negelein E. über die Einfluss der Wellenlänge auf die Verteilung des Atmungsferments (Absorptions spektrum des Atmungsferments). Biochem Z 193: 339-346, 1928.
40. Williamson DH, Lund P, Krebs HA. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem J 103: 514-27, 1967.
41. Wilson DF, Erecinska M. Effect of oxygen concentration on cellular metabolism. Chest 88: 229S-232S, 1985.
42. Wilson DF, Erecinska M, Drown C, Silver IA. The oxygen dependence of cellular energy metabolism. Arch Biochem Biophys 195: 485-493, 1979.
43. Wilson DF, Harrison DK, Vinogradov SA. Oxygen, pH, and mitochondrial oxidative phosphorylation. J Appl Physiol 113: 1838-1845, 2012.
44. Wilson DF, Lee WM, Makonnen S, Finikova O, Apreleva S, Vinogradov SA. Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle. J Appl Physiol 101: 1648-1656, 2006.
45. Wilson DF, Owen CS, Erecinska M. Quantitative dependence of mitochondrial oxidative phosphorylation on oxygen concentration. Arch Biochem Biophys 195: 494-504, 1979.
46. Wilson DF, Mokashi A, Chugh D, Vinogradov SA, Osanai S, Lahiri S. The primary oxygen sensor of the cat carotid body is cytochrome a3 of the mitochondrial respiratory chain. FEBS Lett 351: 370-374, 1994.
47. Wilson DF, Nishiki K, Erecinska M. Energy metabolism in muscle and its regulation during individual contraction-relaxation cycles. Trends Biochem Sci 6: 16-19, 1981.
48. Wilson DF, Owen C, Mela L, Weiner L. Control of mitochondrial respiration by the phosphate potential. Biochem Biophys Res Commun 53: 326-333, 1973.
49. Wilson DF, Stubbs M, Veech RL, Erecinska M, Krebs HA. Equilibrium relations between the oxidation-reduction reactions and ATP synthesis in suspensions of isolated liver cells. Biochem J 140: 57-64, 1974.
50. Wyatt CN, Mustard KJ, Pearson SA, Dallas ML, Atkinson L, Kumar P, Peers C, Hardie DG, Evans AM. AMP-activated protein kinase mediates carotid body excitation by hypoxia. J Biol Chem 282: 8092-8098, 2007.