Human cytomegalovirus UL76 induces chromosome aberrations

Journal of Biomedical Science

Volumn 16, Issue , 2009, Pages

  Siew, Voon Kwan ^a   Duh, Chang Yih ^b   Wang, Shang Kwei ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

H2AFX PROTEIN, HUMAN; HISTONE;

ANIMAL; ARTICLE; CELL CYCLE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; CHROMOSOME ABERRATION; COMET ASSAY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DNA DAMAGE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; GLIOBLASTOMA; HUMAN; METHODOLOGY; TUMOR CELL LINE; VIROLOGY;

ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; CHROMOSOME ABERRATIONS; COMET ASSAY; COS CELLS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA DAMAGE; GENE EXPRESSION REGULATION; GLIOBLASTOMA; HISTONES; HUMANS; MICROSCOPY, FLUORESCENCE;

EID: 76249106205     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-16-107     Document Type: Article

References (46)

1. Kamranvar SA, Gruhne B, Szeles A, Masucci MG: Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma. Oncogene 2007, 26:5115-5123.
2. Everett RD: Interactions between DNA viruses, ND10 and the DNA damage response. Cell Microbiol 2006, 8:365-374.
3. Lilley CE, Schwartz RA, Weitzman MD: Using or abusing: viruses and the cellular DNA damage response. Trends Microbiol 2007, 15:119-126.
4. Sinclair A, Yarranton S, Schelcher C: DNA-damage response pathways triggered by viral replication. Expert Rev Mol Med 2006, 8:1-11.
5. Weitzman MD, Carson CT, Schwartz RA, Lilley CE: Interactions of viruses with the cellular DNA repair machinery. DNA repair 2004, 3:1165-1173.
6. Luo MH, Rosenke K, Czornak K, Fortunato EA: Human cytomegalovirus disrupts both ataxia telangiectasia mutated protein (ATM)-and ATM-Rad3-related kinase-mediated DNA damage responses during lytic infection. J Virol 2007, 81:1934-1950.
7. Hrecka K, Gierszewska M, Srivastava S, Kozaczkiewicz L, Swanson SK, Florens L, Washburn MP, Skowronski J: Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. Proc Natl Acad Sci USA 2007, 104:11778-11783.
8. Schrofelbauer B, Hakata Y, Landau NR: HIV-1 Vpr function is mediated by interaction with the damage-specific DNAbinding protein DDB1. Proc Natl Acad Sci USA 2007, 104:4130-4135.
9. Nguyen ML, Blaho JA: Apoptosis during herpes simplex virus infection. Adv Virus Res 2007, 69:67-97.
10. Wilkinson DE, Weller SK: Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection. J Cell Sci 2006, 119:2695-2703.
11. Marriott SJ, Semmes OJ: Impact of HTLV-I Tax on cell cycle progression and the cellular DNA damage repair response. Oncogene 2005, 24:5986-5995.
12. Mocarski ES, Shenk T, Pass RF: Cytomegalovirus. In Field's Virology 5th edition. Edited by: Knight DM, Howley PM. Philadelphia: Lippincott Williams & Wilkins; 2007:2701-2772.
13. Reddehase MJ: Cytomegaloviruses Molecular Biology and Immunology. Norfolk, UK; Caister Academic Press; 2006.
14. Cheng J, Ke Q, Jin Z, Wang H, Kocher O, Morgan JP, Zhang J, Crumpacker CS: Cytomegalovirus infection causes an increase of arterial blood pressure. PLoS Pathog 2009, 5:e1000427.
15. Reeves M, Sinclair J: Aspects of human cytomegalovirus latency and reactivation. Curr Top Microbiol Immunol 2008, 325:297-313.
16. Fortunato EA, Spector DH: Viral induction of site-specific chromosome damage. Rev Med Virol 2003, 13:21-37.
17. Luleci G, Sakizli M, Gunalp A: Selective chromosomal damage caused by human cytomegalovirus. Acta Virol 1980, 24:341-345.
18. AbuBakar S, Au WW, Legator MS, Albrecht T: Induction of chromosome aberrations and mitotic arrest by cytomegalovirus in human cells. Environ Mol Mutagen 1988, 12:409-420.
19. Bystrevskaya VB, Lobova TV, Smirnov VN, Makarova NE, Kushch AA: Centrosome injury in cells infected with human cytomegalovirus. J Struct Biol 1997, 120:52-60.
20. Nystad M, Fagerheim T, Brox V, Fortunato EA, Nilssen O: Human cytomegalovirus (HCMV) and hearing impairment: Infection of fibroblast cells with HCMV induces chromosome breaks at 1q23.3, between loci DFNA7 and DFNA49-Both involved in dominantly inherited, sensorineural, hearing impairment. Mutat Res 2008, 637:56-65.
21. Fortunato EA, Dell'Aquila ML, Spector DH: Specific chromosome 1 breaks induced by human cytomegalovirus. Proc Natl Acad Sci USA 2000, 97:853-858.
22. Dezelee S, Bras F, Vende P, Simonet B, Nguyen X, Flamand A, Masse MJ: The BamHI fragment 9 of pseudorabies virus contains genes homologous to the UL24, UL25, UL26, and UL 26.5 genes of herpes simplex virus type 1. Virus Res 1996, 42:27-39.
23. Wang S-K, Duh C-Y, Wu C-W: Human cytomegalovirus UL76 encodes a novel virion-associated protein that is able to inhibit viral replication. J Virol 2004, 78:9750-9762.
24. Wang S-K, Duh C-Y, Chang T-T: Cloning and identification of regulatory gene UL76 of human cytomegalovirus. J Gen Virol 2000, 81:2407-2416.
25. Salsman J, Zimmerman N, Chen T, Domagala M, Frappier L: Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PLoS Pathog 2008, 4:e1000100.
26. Ishov AM, Stenberg RM, Maul GG: Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment. J Cell Biol 1997, 138:5-16.
27. Yu D, Silva MC, Shenk T: Functional map of human cytomegalovirus AD169 defined by global mutational analysis. Proc Natl Acad Sci USA 2003, 100:12396-12401.
28. Dunn W, Chou C, Li H, Hai R, Patterson D, Stolc V, Zhu H, Liu F: Functional profiling of a human cytomegalovirus genome. Proc Natl Acad Sci USA 2003, 100:14223-14228.
29. Murphy E, Shenk T: Human cytomegalovirus genome. Curr Top Microbiol Immunol 2008, 325:1-19.
30. Goodrum F, Jordan CT, Terhune SS, High K, Shenk T: Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations. Blood 2004, 104:687-695.
31. Goodrum FD, Jordan CT, High K, Shenk T: Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency. Proc Natl Acad Sci USA 2002, 99:16255-16260.
32. Knizewski L, Kinch L, Grishin NV, Rychlewski L, Ginalski K: Human herpesvirus 1 UL24 gene encodes a potential PD-(D/E)XK endonuclease. J Virol 2006, 80:2575-2577.
33. Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM: A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000, 10:886-895.
34. Jacobson JG, Chen SH, Cook WJ, Kramer MF, Coen DM: Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice. Virology 1998, 242:161-169.
35. Blakeney S, Kowalski J, Tummolo D, DeStefano J, Cooper D, Guo M, Gangolli S, Long D, Zamb T, Natuk RJ, Visalli RJ: Herpes simplex virus type 2 UL24 gene is a virulence determinant in murine and guinea pig disease models. J Virol 2005, 79:10498-10506.
36. Nascimento R, Parkhouse RM: Murine gammaherpesvirus 68 ORF20 induces cell-cycle arrest in G2 by inhibiting the Cdc2cyclin B complex. J Gen Virol 2007, 88:1446-1453.
37. Nascimento R, Dias JD, Parkhouse RM: The conserved UL24 family of human alpha, beta and gamma herpesviruses induces cell cycle arrest and inactivation of the cyclinB/cdc2 complex. Arch Virol 2009, 154:1143-1149.
38. Kosinski J, Feder M, Bujnicki JM: The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function. BMC bioinformatics 2005, 6:172-184.
39. Stow ND: Packaging of genomic and amplicon DNA by the herpes simplex virus type 1 UL25-null mutant KUL25NS. J Virol 2001, 75:10755-10765.
40. Bowman BR, Welschhans RL, Jayaram H, Stow ND, Preston VG, Quiocho FA: Structural characterization of the UL25 DNA-pack aging protein from herpes simplex virus type 1. J Virol 2006, 80:2309-2317.
41. Rao X, Zhang Y, Yi Q, Hou H, Xu B, Chu L, Huang Y, Zhang W, Fenech M, Shi Q: Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res 2008, 646:41-49.
42. Stucki M, Jackson SP: gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA repair 2006, 5:534-543.
43. Lilley CE, Carson CT, Muotri AR, Gage FH, Weitzman MD: DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proc Natl Acad Sci USA 2005, 102:5844-5849.
44. Kops GJ, Weaver BA, Cleveland DW: On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer 2005, 5:773-785.
45. Rajagopalan H, Lengauer C: Aneuploidy and cancer. Nature 2004, 432:338-341.
46. Ganem NJ, Godinho SA, Pellman D: A mechanism linking extra centrosomes to chromosomal instability. Nature 2009, 460:278-282.