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Volumn 461, Issue 1-2, 2014, Pages 157-162

The effect of simvastatin-loaded polymeric microspheres in a critical size bone defect in the rabbit calvaria

Author keywords

Bone substitutions; Critical sized defect; PLGA microspheres; Simvastatin

Indexed keywords

ALUMINOSILICATE CALCIUM; BONE CEMENT; POLYGLACTIN; POLYMER; SIMVASTATIN; SOLVENT; WATER OIL CREAM; EMULSION; LACTIC ACID; MICROCAPSULE; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

EID: 84890281303     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.11.046     Document Type: Article
Times cited : (58)

References (30)
  • 1
    • 0028146259 scopus 로고
    • Unicortical critical size defect of rabbit tibia is larger than 8 mm
    • M.D. Aaboe, E.M. Pinholt, and E. Hjørting-Hansen Unicortical critical size defect of rabbit tibia is larger than 8 mm J. Craniofac. Surg. 5 1994 201 203 (Pubitemid 24236315)
    • (1994) Journal of Craniofacial Surgery , vol.5 , Issue.3 , pp. 201-203
    • Aaboe, M.1    Pinholt, E.M.2    Hjorting-Hansen, E.3
  • 2
    • 0025672856 scopus 로고
    • Lovastatin and simvastatin - Inhibitors of HMG CoA reductase and cholesterol biosynthesis
    • A.W. Alberts Lovastatin and simvastatin - inhibitors of HMG CoA reductase and cholesterol biosynthesis Cardiology 77 1990 14 21
    • (1990) Cardiology , vol.77 , pp. 14-21
    • Alberts, A.W.1
  • 3
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • DOI 10.1016/S0169-409X(97)00048-3, PII S0169409X97000483
    • J.M. Anderson, and M.S. Shive Biodegradation and biocompatibility of PLA and PLGA microspheres Adv. Drug Deliv. Rev. 28 1997 5 24 (Pubitemid 27497671)
    • (1997) Advanced Drug Delivery Reviews , vol.28 , Issue.1 , pp. 5-24
    • Anderson, J.M.1    Shive, M.S.2
  • 4
    • 3042580179 scopus 로고    scopus 로고
    • Simvastatin promotes osteogenesis around titanium implants
    • Y. Ayukawa, A. Okamura, and K. Koyano Simvastatin promotes osteogenesis around titanium implants Clin. Oral Implants Res. 15 2004 346 350
    • (2004) Clin. Oral Implants Res. , vol.15 , pp. 346-350
    • Ayukawa, Y.1    Okamura, A.2    Koyano, K.3
  • 5
    • 3042580179 scopus 로고    scopus 로고
    • Simvastatin promotes osteogenesis around titanium implants: A histological and histometrical study in rats
    • DOI 10.1046/j.1600-0501.2003.01015.x
    • Y. Ayukawa, A. Okamura, and K. Koyano Simvastatin promotes osteogenesis around titanium implants. A histological and histometrical study in rats Clin. Oral Implants Res. 15 2004 346 350 (Pubitemid 40340577)
    • (2004) Clinical Oral Implants Research , vol.15 , Issue.3 , pp. 346-350
    • Ayukawa, Y.1    Okamura, A.2    Koyano, K.3
  • 6
    • 59649102438 scopus 로고    scopus 로고
    • Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats
    • Y. Ayukawa, E. Yasukawa, Y. Moriyama, Y. Ogino, H. Wada, I. Atsuta, and K. Koyano Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 107 2009 336 342
    • (2009) Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. , vol.107 , pp. 336-342
    • Ayukawa, Y.1    Yasukawa, E.2    Moriyama, Y.3    Ogino, Y.4    Wada, H.5    Atsuta, I.6    Koyano, K.7
  • 7
    • 0033564706 scopus 로고    scopus 로고
    • Posterolateral lumbar intertransverse process spine arthrodesis with recombinant human bone morphogenetic protein 2/hydroxyapatite-tricalcium phosphate after laminectomy in the nonhuman primate
    • DOI 10.1097/00007632-199906150-00002
    • S.D. Boden, G.J. Martin Jr., M.A. Morone, J.L. Ugbo, and P.A. Moskovitz Posterolateral lumbar intertransverse process spine arthrodesis with recombinant human bone morphogenetic protein 2/hydroxyapatite-tricalcium phosphate after laminectomy in the nonhuman primate Spine 24 1999 1179 1185 (Pubitemid 29279459)
    • (1999) Spine , vol.24 , Issue.12 , pp. 1179-1185
    • Boden, S.D.1    Martin, G.J.2    Morone, M.A.3    Ugbo, J.L.4
  • 8
    • 33746358173 scopus 로고    scopus 로고
    • Bone tissue formation adjacent to implants placed in fresh extraction sockets: An experimental study in dogs
    • DOI 10.1111/j.1600-0501.2006.01270.x
    • D. Botticelli, L.G. Persson, J. Lindhe, and T. Berglundh Bone tissue formation adjacent to implants placed in fresh extraction sockets: an experimental study in dogs Clin. Oral Implants Res. 17 2006 351 358 (Pubitemid 44114698)
    • (2006) Clinical Oral Implants Research , vol.17 , Issue.4 , pp. 351-358
    • Botticelli, D.1    Persson, L.G.2    Lindhe, J.3    Berglundh, T.4
  • 9
    • 77952285581 scopus 로고    scopus 로고
    • Simvastatin promotes osteoblast viability and differentiation via Ras/Smad/Erk/BMP-2 signaling pathway
    • P.-Y. Chen, J.-S. Sun, Y.-H. Tsuang, M.-H. Chen, P.-W. Weng, and F.-H. Lin Simvastatin promotes osteoblast viability and differentiation via Ras/Smad/Erk/BMP-2 signaling pathway Nutr. Res. 30 2010 191 199
    • (2010) Nutr. Res. , vol.30 , pp. 191-199
    • Chen, P.-Y.1    Sun, J.-S.2    Tsuang, Y.-H.3    Chen, M.-H.4    Weng, P.-W.5    Lin, F.-H.6
  • 10
    • 58449130151 scopus 로고    scopus 로고
    • Effects of simvastatin on bone healing around titanium implants in osteoporotic rats
    • Z. Du, J. Chen, F. Yan, and Y. Xiao Effects of simvastatin on bone healing around titanium implants in osteoporotic rats Clin. Oral Implants Res. 20 2009 145 150
    • (2009) Clin. Oral Implants Res. , vol.20 , pp. 145-150
    • Du, Z.1    Chen, J.2    Yan, F.3    Xiao, Y.4
  • 11
    • 33746972807 scopus 로고    scopus 로고
    • Calcium phosphate cements as bone drug delivery systems: A review
    • DOI 10.1016/j.jconrel.2006.04.007, PII S0168365906001775
    • M.P. Ginebra, T. Traykova, and J.A. Planell Calcium phosphate cements as bone drug delivery systems: a review J. Control. Release 113 2006 102 110 (Pubitemid 44202359)
    • (2006) Journal of Controlled Release , vol.113 , Issue.2 , pp. 102-110
    • Ginebra, M.P.1    Traykova, T.2    Planell, J.A.3
  • 13
    • 84911307627 scopus 로고
    • The critical size defect as an experimental model to test bone repair materials
    • J.O. Hollinger, and J.C. Kleinschmidt The critical size defect as an experimental model to test bone repair materials J. Craniofac. Surg. 1 1990 60 68
    • (1990) J. Craniofac. Surg. , vol.1 , pp. 60-68
    • Hollinger, J.O.1    Kleinschmidt, J.C.2
  • 14
    • 27744519739 scopus 로고    scopus 로고
    • Statins modulate the levels of osteoprotegerin/receptor activator of NFκB ligand mRNA in mouse bone-cell cultures
    • DOI 10.1055/s-2005-870538
    • H. Kaji, M. Kanatani, T. Sugimoto, and K. Chihara Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures Horm. Metab. Res. 37 2005 589 592 (Pubitemid 41597568)
    • (2005) Hormone and Metabolic Research , vol.37 , Issue.10 , pp. 589-592
    • Kaji, H.1    Kanatani, M.2    Sugimoto, T.3    Chihara, K.4
  • 15
    • 3042856516 scopus 로고    scopus 로고
    • Comparative study on sustained release of human growth hormone from semi-crystalline poly(L-lactic acid) and amorphous poly(D,L-lactic-co-glycolic acid) microspheres: Morphological effect on protein release
    • DOI 10.1016/j.jconrel.2004.04.020, PII S0168365904002007
    • H.K. Kim, and T.G. Park Comparative study on sustained release of human growth hormone from semi-crystalline poly(l-lactic acid) and amorphous poly(d,l-lactic-co-glycolic acid) microspheres: morphological effect on protein release J. Control. Release 98 2004 115 125 (Pubitemid 38881612)
    • (2004) Journal of Controlled Release , vol.98 , Issue.1 , pp. 115-125
    • Kim, H.K.1    Park, T.G.2
  • 17
    • 0037318567 scopus 로고    scopus 로고
    • Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation
    • DOI 10.1210/en.2002-220682
    • T. Maeda, T. Kawane, and N. Horiuchi Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation Endocrinology 144 2003 681 692 (Pubitemid 36205242)
    • (2003) Endocrinology , vol.144 , Issue.2 , pp. 681-692
    • Maeda, T.1    Kawane, T.2    Horiuchi, N.3
  • 19
    • 0037384716 scopus 로고    scopus 로고
    • Effect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: A 1-year longitudinal study
    • DOI 10.1016/S8756-3282(03)00034-6
    • A. Montagnani, S. Gonnelli, C. Cepollaro, S. Pacini, M.S. Campagna, M.B. Franci, B. Lucani, and C. Gennari Effect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: a 1-year longitudinal study Bone 32 2003 427 433 (Pubitemid 36410317)
    • (2003) Bone , vol.32 , Issue.4 , pp. 427-433
    • Montagnani, A.1    Gonnelli, S.2    Cepollaro, C.3    Pacini, S.4    Campagna, M.S.5    Franci, M.B.6    Lucani, B.7    Gennari, C.8
  • 21
    • 84890554958 scopus 로고    scopus 로고
    • Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss
    • Y. Nakashima, and T. Haneji Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss PLoS ONE 8 2013 e72033
    • (2013) PLoS ONE , vol.8 , pp. 72033
    • Nakashima, Y.1    Haneji, T.2
  • 22
    • 0023855203 scopus 로고
    • One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats
    • H. Okada, T. Heya, Y. Ogawa, and T. Shimamoto One-mounth release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats J Pharmacol Exp Ther. 244 1988 744 750 (Pubitemid 18076624)
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.244 , Issue.2 , pp. 744-750
    • Okada, H.1    Heya, T.2    Ogawa, Y.3    Shimamoto, T.4
  • 24
    • 0031262601 scopus 로고    scopus 로고
    • Placement of implants into fresh extraction sites: 4 to 7 years retrospective evaluation of 95 immediate implants
    • D. Schwartz-Arad, and G. Chaushu Placement of implants into fresh extraction sites: 4 to 7 years retrospective evaluation of 95 immediate implants J. Periodontol. 68 1997 1110 1116 (Pubitemid 127513678)
    • (1997) Journal of Periodontology , vol.68 , Issue.11 , pp. 1110-1116
    • Schwartz-Arad, D.1    Chaushu, G.2
  • 25
    • 0042666802 scopus 로고    scopus 로고
    • Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells
    • DOI 10.1016/S0006-291X(03)01408-6
    • C. Song, Z. Guo, Q. Ma, Z. Chen, Z. Liu, H. Jia, and G. Dang Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells Biochem. Biophys. Res. Commun. 308 2003 458 462 (Pubitemid 36945513)
    • (2003) Biochemical and Biophysical Research Communications , vol.308 , Issue.3 , pp. 458-462
    • Song, C.1    Guo, Z.2    Ma, Q.3    Chen, Z.4    Liu, Z.5    Jia, H.6    Dang, G.7
  • 28
    • 84881030307 scopus 로고    scopus 로고
    • Comparison of histological and three-dimensional characteristics of porous titanium granules and deproteinized bovine particulate grafts used for sinus floor augmentation in humans: A pilot study
    • S. Vandeweghe, C. Leconte, D. Ono, P.G. Coelho, and R. Jimbo Comparison of histological and three-dimensional characteristics of porous titanium granules and deproteinized bovine particulate grafts used for sinus floor augmentation in humans: a pilot study Implant Dent. 22 2013 339 343
    • (2013) Implant Dent. , vol.22 , pp. 339-343
    • Vandeweghe, S.1    Leconte, C.2    Ono, D.3    Coelho, P.G.4    Jimbo, R.5
  • 29
    • 80755163519 scopus 로고    scopus 로고
    • Effects of simvastatin on osseointegration in a canine total hip arthroplasty model: An experimental study
    • H. Yin, J. Li, X. Yu, and Z. Fu Effects of simvastatin on osseointegration in a canine total hip arthroplasty model: an experimental study J. Arthroplasty 26 2011 1534 1539
    • (2011) J. Arthroplasty , vol.26 , pp. 1534-1539
    • Yin, H.1    Li, J.2    Yu, X.3    Fu, Z.4
  • 30
    • 33645996058 scopus 로고    scopus 로고
    • Minimally invasive extraction and immediate implant placement: The preservation of esthetics
    • K.J. Zeren Minimally invasive extraction and immediate implant placement: the preservation of esthetics Int. J. Periodontics Restorative Dent. 26 2006 171 181 (Pubitemid 43592507)
    • (2006) International Journal of Periodontics and Restorative Dentistry , vol.26 , Issue.2 , pp. 171-181
    • Zeren, K.J.1


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