Alterations of brain anatomy in mouse model of MDD created by replacement of homologous mouse DNA sequence with an illness-associated 6-base human CREB1 promoter sequence

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 165, Issue 1, 2014, Pages 1-8

  Zubenko, George S ^a,b   Hughes, Hugh B ^a   Hitchens, T Kevin ^b   Cohen, Bruce M ^c,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MCLEAN HOSPITAL   (United States)

Author keywords

Animal model; Brain anatomy; Genetics; Major depression; Mouse

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; CREB1 PROTEIN, HUMAN;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SIZE; BRAIN THIRD VENTRICLE; BRAIN TISSUE; CONTROLLED STUDY; CORPUS CALLOSUM; CORPUS STRIATUM; DNA SEQUENCE; FEMALE; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HIPPOCAMPUS; LATERAL BRAIN VENTRICLE; MAGNETIC RESONANCE MICROSCOPY; MAJOR DEPRESSION; MALE; MICROSCOPY; MOUSE; NEUROANATOMY; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROMOTER REGION; SURFACE PROPERTY; THREE DIMENSIONAL IMAGING; ANATOMY AND HISTOLOGY; ANIMAL; C57BL MOUSE; DISEASE MODEL; EMBRYOLOGY; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; HUMAN; SEQUENCE HOMOLOGY; TRANSGENIC MOUSE;

ANIMALIA; MUS;

ANIMALS; CORPUS CALLOSUM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LATERAL VENTRICLES; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; SEQUENCE HOMOLOGY; TRANSFECTION;

EID: 84890239907     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32198     Document Type: Article

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