-
2
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006;441:431-6.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
3
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg J. Stat proteins and oncogenesis. J Clin Investig 2002;109:1139-42.
-
(2002)
J Clin Investig
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
4
-
-
28644445445
-
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
-
Kortylewski M, Kujawski M, Wang T, et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nature Med 2005;11:1314-21.
-
(2005)
Nature Med
, vol.11
, pp. 1314-1321
-
-
Kortylewski, M.1
Kujawski, M.2
Wang, T.3
-
5
-
-
33845865825
-
Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
-
Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev 2007;7:41-51.
-
(2007)
Nat Rev
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
6
-
-
58649119388
-
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
-
Kortylewski M, Xin H, Kujawski M, et al. Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell 2009;15:114-23.
-
(2009)
Cancer Cell
, vol.15
, pp. 114-123
-
-
Kortylewski, M.1
Xin, H.2
Kujawski, M.3
-
7
-
-
77951936316
-
IL-17 Promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells
-
He D, Li H, Yusuf N, et al. IL-17 Promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol 2010;184:2281-8.
-
(2010)
J Immunol
, vol.184
, pp. 2281-2288
-
-
He, D.1
Li, H.2
Yusuf, N.3
-
8
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
Kaplan DH, Shankaran V, Dighe AS, et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.Proc Natl Acad Sci U S A 1998;95:7556-61.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
-
9
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009;206:1457-64.
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
-
10
-
-
62449162980
-
IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation
-
Xiao M, Wang C, Zhang J, Li Z, Zhao X, Qin Z. IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation. Cancer Res 2009;69:2010-7.
-
(2009)
Cancer Res
, vol.69
, pp. 2010-2017
-
-
Xiao, M.1
Wang, C.2
Zhang, J.3
Li, Z.4
Zhao, X.5
Qin, Z.6
-
11
-
-
45549109366
-
+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis
-
+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis. Cancer Res 2008;68:3924-30.
-
(2008)
Cancer Res
, vol.68
, pp. 3924-3930
-
-
Yusuf, N.1
Nasti, T.H.2
Katiyar, S.K.3
-
12
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev 2003;3:133-46.
-
(2003)
Nat Rev
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
13
-
-
0242416575
-
Cytokines and transcription factors that regulate T helper cell differentiation: New players and new insights
-
Agnello D, Lankford CS, Bream J, et al. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol 2003;23:147-61.
-
(2003)
J Clin Immunol
, vol.23
, pp. 147-161
-
-
Agnello, D.1
Lankford, C.S.2
Bream, J.3
-
14
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009;15:1016-22.
-
(2009)
Nat Med
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
-
15
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
Chen Z, Laurence A, Kanno Y, et al. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc Natl Acad Sci U S A 2006;103:8137-42.
-
(2006)
Proc Natl Acad Sci U S a
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
Laurence, A.2
Kanno, Y.3
-
16
-
-
44049100797
-
Th17 cells: A new fate for differentiating helper T cells
-
Chen Z, O'Shea JJ. Th17 cells: a new fate for differentiating helper T cells. Immunol Res 2008;41:87-102.
-
(2008)
Immunol Res
, vol.41
, pp. 87-102
-
-
Chen, Z.1
O'Shea, J.J.2
-
17
-
-
67651094058
-
Endogenous IL-17 contributes to reduced tumor growth and metastasis
-
Kryczek I, Wei S, Szeliga W, Vatan L, Zou W. Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 2009; 114:357-9.
-
(2009)
Blood
, vol.114
, pp. 357-359
-
-
Kryczek, I.1
Wei, S.2
Szeliga, W.3
Vatan, L.4
Zou, W.5
-
18
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N, Muranski P, Chung Y, et al. T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009;31:787-98.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
-
20
-
-
48849101281
-
The prevalence of Th17 cells in patients with gastric cancer
-
Zhang B, Rong G, Wei H, et al. The prevalence of Th17 cells in patients with gastric cancer. Biochem Biophys Res Commun 2008;374:533-7.
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 533-537
-
-
Zhang, B.1
Rong, G.2
Wei, H.3
-
21
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang JP, Yan J, Xu J, et al. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol 2009;50:980-9.
-
(2009)
J Hepatol
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
-
22
-
-
67651176150
-
Raf-1 addiction in Ras-induced skin carcinogenesis
-
Ehrenreiter K, Kern F, Velamoor V, et al. Raf-1 addiction in Ras-induced skin carcinogenesis. Cancer Cell 2009;16:149-60.
-
(2009)
Cancer Cell
, vol.16
, pp. 149-160
-
-
Ehrenreiter, K.1
Kern, F.2
Velamoor, V.3
-
23
-
-
33746534417
-
IL-23 promotes tumour incidence and growth
-
Langowski JL, Zhang X, Wu L, et al. IL-23 promotes tumour incidence and growth. Nature 2006;442:461-5.
-
(2006)
Nature
, vol.442
, pp. 461-465
-
-
Langowski, J.L.1
Zhang, X.2
Wu, L.3
-
24
-
-
0036754255
-
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
-
Nakae S, Komiyama Y, Nambu A, et al. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002;17:375-87.
-
(2002)
Immunity
, vol.17
, pp. 375-387
-
-
Nakae, S.1
Komiyama, Y.2
Nambu, A.3
-
25
-
-
70449494642
-
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
-
Yi T, Chen Y, Wang L, et al. Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood 2009;114:3101-12.
-
(2009)
Blood
, vol.114
, pp. 3101-3112
-
-
Yi, T.1
Chen, Y.2
Wang, L.3
-
26
-
-
4944239032
-
Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
-
Chan KS, Sano S, Kiguchi K, et al. Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis.J Clin Investig 2004;114:720-8.
-
(2004)
J Clin Investig
, vol.114
, pp. 720-728
-
-
Chan, K.S.1
Sano, S.2
Kiguchi, K.3
-
27
-
-
53349099219
-
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
-
Cheng P, Corzo CA, Luetteke N, et al. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med 2008;205:2235-49.
-
(2008)
J Exp Med
, vol.205
, pp. 2235-2249
-
-
Cheng, P.1
Corzo, C.A.2
Luetteke, N.3
-
28
-
-
55849107422
-
Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice
-
Kujawski M, Kortylewski M, Lee H, Herrmann A, Kay H, Yu H. Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. J Clin Investig 2008;118:3367-77.
-
(2008)
J Clin Investig
, vol.118
, pp. 3367-3377
-
-
Kujawski, M.1
Kortylewski, M.2
Lee, H.3
Herrmann, A.4
Kay, H.5
Yu, H.6
-
29
-
-
29644442445
-
Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression
-
Bunt SK, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J Immunol 2006;176:284-90.
-
(2006)
J Immunol
, vol.176
, pp. 284-290
-
-
Bunt, S.K.1
Sinha, P.2
Clements, V.K.3
Leips, J.4
Ostrand-Rosenberg, S.5
-
30
-
-
49649104776
-
IL-6 regulates neutrophil trafficking during acute inflammation via STAT3
-
Fielding CA, McLoughlin RM, McLeod L, et al. IL-6 regulates neutrophil trafficking during acute inflammation via STAT3. J Immunol 2008;181:2189-95.
-
(2008)
J Immunol
, vol.181
, pp. 2189-2195
-
-
Fielding, C.A.1
McLoughlin, R.M.2
McLeod, L.3
-
31
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009;9:798-809.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
32
-
-
55049118394
-
Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction
-
Ogura H, Murakami M, Okuyama Y, et al. Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction. Immunity 2008;29:628-36.
-
(2008)
Immunity
, vol.29
, pp. 628-636
-
-
Ogura, H.1
Murakami, M.2
Okuyama, Y.3
-
34
-
-
0034658541
-
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
-
Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000;19:2548-56.
-
(2000)
Oncogene
, vol.19
, pp. 2548-2556
-
-
Hirano, T.1
Ishihara, K.2
Hibi, M.3
-
35
-
-
0032983865
-
Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis
-
Moore RJ, Owens DM, Stamp G, et al. Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat Med 1999;5:828-31.
-
(1999)
Nat Med
, vol.5
, pp. 828-831
-
-
Moore, R.J.1
Owens, D.M.2
Stamp, G.3
-
36
-
-
70349668946
-
The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans
-
Charles KA, Kulbe H, Soper R, et al. The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.J Clin Investig 2009;119:3011-23.
-
(2009)
J Clin Investig
, vol.119
, pp. 3011-3023
-
-
Charles, K.A.1
Kulbe, H.2
Soper, R.3
-
37
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
-
Lee H, Herrmann A, Deng JH, et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell 2009;15:283-93.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
-
38
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo DG, Barreto JB, Andreu P, et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009;16:91-102.
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Andreu, P.3
|