Comparative functional characterization of canine IgG subclasses

Veterinary Immunology and Immunopathology

Volumn 157, Issue 1-2, 2014, Pages 31-41

  Bergeron, Lisa M ^a   McCandless, Erin E ^a   Dunham, Steve ^a   Dunkle, Bill ^a   Zhu, Yaqi ^a   Shelly, John ^a   Lightle, Sandra ^a   Gonzales, Andrea ^a   Bainbridge, Graeme ^a  

^a ZOETIS   (United States)

Author keywords

ADCC; Canine; CDC; CDR; Effector functions; Fc receptor; IgG subclass; Immunoglobulin

Indexed keywords

COMPLEMENT COMPONENT C1Q; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FC RECEPTOR; FC RECEPTOR IIA; FC RECEPTOR IIB; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; PROTEIN A; PROTEIN G;

AFFINITY CHROMATOGRAPHY; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN PURIFICATION; ARTICLE; CHIMERA; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEMENT FIXATION; CONTROLLED STUDY; CROSS REACTION; DOG; EFFECTOR CELL; EX VIVO STUDY; FEMALE; FUNCTIONAL GENOMICS; GENETIC ASSOCIATION; HUMAN; IMMUNOGENETICS; IN VITRO STUDY; MAMMALIAN GENETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA HALF LIFE; RECEPTOR BINDING; RECEPTOR GENE; SEQUENCE ALIGNMENT; WESTERN BLOTTING;

ADCC; ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY; CANINE; CDC; CDR; CELL-MEDIATED CYTOTOXICITY; COMPLEMENTARITY DETERMINING REGION; EFFECTOR FUNCTIONS; FC RECEPTOR; IGG SUBCLASS; IMMUNOGLOBULIN;

ANIMALS; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; CLONING, MOLECULAR; CROSS REACTIONS; DOGS; HUMANS; IMMUNOGLOBULIN G; MICE; RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUE; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS; RNA;

EID: 84890200912     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2013.10.018     Document Type: Article

References (37)

1. Almagro J.C., Fransson J. Humanization of antibodies. Front. Biosci. 2008, 13:1619-1633.
2. Armour K.L., Clark M.R., et al. Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities. Eur. J. Immunol. 1999, 29(8):2613-2624.
3. Bruggemann M., Williams G.T., et al. Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J. Exp. Med. 1987, 166(5):1351-1361.
4. Carter P. Improving the efficacy of antibody-based cancer therapies. Nat. Rev. Cancer 2001, 1(2):118-129.
5. Clynes R.A., Towers T.L., et al. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat. Med. 2000, 6(4):443-446.
6. Daeron M. Fc receptor biology. Annu. Rev. Immunol. 1997, 15:203-234.
7. Davies D.R., Metzger H. Structural basis of antibody function. Annu. Rev. Immunol. 1983, 1:87-117.
8. Deplazes P., Smith N.C., et al. Specific IgG1 and IgG2 antibody responses of dogs to Leishmania infantum and other parasites. Parasite Immunol. 1995, 17(9):451-458.
9. Garred P., Michaelsen T.E., et al. The IgG subclass pattern of complement activation depends on epitope density and antibody and complement concentration. Scand. J. Immunol. 1989, 30(3):379-382.
10. Ghetie V., Hubbard J.G., et al. Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur. J. Immunol. 1996, 26(3):690-696.
11. Gonzales N.R., De Pascalis R., et al. Minimizing the immunogenicity of antibodies for clinical application. Tumour Biol. 2005, 26(1):31-43.
12. Hibbs M.L., Bonadonna L., et al. Molecular cloning of a human immunoglobulin G Fc receptor. Proc. Natl. Acad. Sci. U.S.A. 1988, 85(7):2240-2244.
13. Hibbs M.L., Walker I.D., et al. The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones. Proc. Natl. Acad. Sci. U.S.A. 1986, 83(18):6980-6984.
14. Israel E.J., Wilsker D.F., et al. Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn. Immunology 1996, 89(4):573-578.
15. Jefferis R. Antibody therapeutics: isotype and glycoform selection. Expert Opin. Biol. Ther. 2007, 7(9):1401-1413.
16. Jefferis R., Lund J., et al. Recognition sites on human IgG for Fc gamma receptors: the role of glycosylation. Immunol. Lett. 1995, 44(2-3):111-117.
17. Johnson J.S., Vaughan J.H. Canine immunoglobulins, I. Evidence for six immunoglobulin classes. J. Immunol. 1967, 98(5):923-934.
18. Johnson J.S., Vaughan J.H., et al. Canine immunoglobulins. II. Antibody activities in six immunoglobulin classes. J. Immunol. 1967, 98(5):935-940.
19. Junghans R.P., Anderson C.L. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor. Proc. Natl. Acad. Sci. U.S.A. 1996, 93(11):5512-5516.
20. Kacskovics I., Wu Z., et al. Cloning and characterization of the bovine MHC class I-like Fc receptor. J. Immunol. 2000, 164(4):1889-1897.
21. Kenneth Murphy P.T., Walport M. Janeway's Immunobiology 2008, Taylor & Francis Group, LLC/Garland Science, New York, NY/Abingdon, UK.
22. Leandro C., Santos-Gomes G.M., et al. Cell mediated immunity and specific IgG1 and IgG2 antibody response in natural and experimental canine leishmaniosis. Vet. Immunol. Immunopathol. 2001, 79(3-4):273-284.
23. Lightle S., Aykent S., et al. Mutations within a human IgG2 antibody form distinct and homogeneous disulfide isomers but do not affect Fc gamma receptor or C1q binding. Protein Sci. 2010, 19(4):753-762.
24. Mazza G., Duffus W.P., et al. The separation and identification by monoclonal antibodies of dog IgG fractions. J. Immunol. Methods 1993, 161(2):193-203.
25. Mazza G., Whiting A.H., et al. Development of an enzyme-linked immunosorbent assay for the detection of IgG subclasses in the serum of normal and diseased dogs. Res. Vet. Sci. 1994, 57(2):133-139.
26. Mazza G., Whiting A.H., et al. Preparation of monoclonal antibodies specific for the subclasses of canine IgG. Res. Vet. Sci. 1994, 57(2):140-145.
27. McKenzie S.E., Keller M.A., et al. Characterization of the 5'-flanking transcriptional regulatory region of the human Fc gamma receptor gene, Fc gamma RIIA. Mol. Immunol. 1992, 29(10):1165-1174.
28. Moore G.L., Chen H., et al. Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions. MAbs 2010, 2(2):181-189.
29. Nakamura R., Sato Y., et al. Presence and primary sequence of a high-affinity IgG receptor on canine mastocytoma (CM-MC) cells. Immunogenetics 2003, 55(4):271-274.
30. Nimmerjahn F., Ravetch J.V. Fcgamma receptors: old friends and new family members. Immunity 2006, 24(1):19-28.
31. Praetor A., Hunziker W. beta(2)-Microglobulin is important for cell surface expression and pH-dependent IgG binding of human FcRn. J. Cell Sci. 2002, 115(Pt 11):2389-2397.
32. Ravetch J.V., Bolland S. IgG Fc receptors. Annu. Rev. Immunol. 2001, 19:275-290.
33. Rogers K.A., Scinicariello F., et al. Identification and characterization of macaque CD89 (immunoglobulin A Fc receptor). Immunology 2004, 113(2):178-186.
34. Schifferli J.A., Ng Y.C., et al. The role of complement and its receptor in the elimination of immune complexes. N. Engl. J. Med. 1986, 315(8):488-495.
35. Tang L., Sampson C., et al. Cloning and characterization of cDNAs encoding four different canine immunoglobulin gamma chains. Vet. Immunol. Immunopathol. 2001, 80(3-4):259-270.
36. Winter G., Harris W.J. Humanized antibodies. Trends Pharmacol. Sci. 1993, 14(5):139-143.
37. Xia P., Liu Y., et al. Molecular cloning and characterization of a porcine Fc gamma RIIb sub-isoform (FcgammaRIIb1). Vet. Immunol. Immunopathol. 2011, 141(1-2):144-150.