β2-microglobulin is important for cell surface expression and pH-dependent IgG binding of human FcRn

Journal of Cell Science

Volumn 115, Issue 11, 2002, Pages 2389-2397

  Praetor, Asja ^a   Hunziker, Walter ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Endoplasmic reticulum; Human immunoglobulin G; Major histocompatibility complex; Oligomerization

Indexed keywords

BETA 2 MICROGLOBULIN; FC RECEPTOR; IMMUNOGLOBULIN G; FC RECEPTOR, NEONATAL; HLA ANTIGEN CLASS 1; LEUKOCYTE ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; RIBOPHORIN;

ALPHA CHAIN; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; MELANOMA CELL; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; ANIMAL; CELL CULTURE; EUKARYOTIC CELL; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMAL; ANTIGENS, CD; ANTIGENS, SURFACE; BETA 2-MICROGLOBULIN; CELLS, CULTURED; ENDOPLASMIC RETICULUM; EUKARYOTIC CELLS; HUMAN; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, FC; ANIMALS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS;

EID: 0036591969     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

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2. Beta 2-microglobulin co-distributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat
3. Crystal structure of the complex of rat neonatal Fc receptor with Fc
4. Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in β2m gene expression
5. Multiple roles for the major histocompatibility complex class I-related receptor FcRn
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8. Epithelial transcytosis of immunoglobulins
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11. Increased clearance of IgG in mice that lack beta(2)-microglobulin - Possible protective role of FcRn
12. Expression of the neonatal fc receptor, FcRn, on human intestinal epithelial cells
13. The protection receptor for IgG catabolism is the beta(2)-microglobulin-containing neonatal intestinal transport receptor./
14. Co-localization of the neonatal Fc-gamma receptor and IgG in human placental term syncytiotrophoblasts
15. Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex: Mechanism of ph-dependent binding
16. Mechanisms of MHC class I-restricted antigen processing
17. Intracellular traffic of the MHC class I-like IgG Fc receptor, FcRn, expressed in epithelial MDCK cells
18. The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells - Evidence for a role of beta-catenin/Tcf/Lef signaling
19. Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat
20. An Fc receptor structurally related to MHC class I antigens
21. Nonvectorial surface transport, endocytosis via a di-leucine-based motif, and bidirectional transcytosis of chimera encoding the cytosolic tail of rat FcRn expressed in Madin-Darby canine kidney cells
22. Identification of critical IgG binding epitopes on the neonatal Fc receptor
23. Beta2-microglobulin deficient mice lack CD4-8+ cytolytic T cells