-
1
-
-
0036269402
-
Promoter specificity and biological activity of tethered AP-1 dimers
-
Bakiri, L., Matsuo, K., Wisniewska, M., Wagner, E. F. and Yaniv, M. (2002). Promoter specificity and biological activity of tethered AP-1 dimers. Mol. Cell. Biol. 22, 4952-4964.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4952-4964
-
-
Bakiri, L.1
Matsuo, K.2
Wisniewska, M.3
Wagner, E.F.4
Yaniv, M.5
-
2
-
-
32344453096
-
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells
-
Beard, C., Hochedlinger, K., Plath, K., Wutz, A. and Jaenisch, R. (2006). Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis 44, 23-28.
-
(2006)
Genesis
, vol.44
, pp. 23-28
-
-
Beard, C.1
Hochedlinger, K.2
Plath, K.3
Wutz, A.4
Jaenisch, R.5
-
3
-
-
5344272498
-
Adiponectin and its receptors are expressed in bone-forming cells
-
Berner, H. S., Lyngstadaas, S. P., Spahr, A., Monjo, M., Thommesen, L., Drevon, C. A., Syversen, U. and Reseland, J. E. (2004). Adiponectin and its receptors are expressed in bone-forming cells. Bone 35, 842-849.
-
(2004)
Bone
, vol.35
, pp. 842-849
-
-
Berner, H.S.1
Lyngstadaas, S.P.2
Spahr, A.3
Monjo, M.4
Thommesen, L.5
Drevon, C.A.6
Syversen, U.7
Reseland, J.E.8
-
4
-
-
47049124039
-
Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia
-
Bozec, A., Bakiri, L., Hoebertz, A., Eferl, R., Schilling, A. F., Komnenovic, V., Scheuch, H., Priemel, M., Stewart, C. L., Amling, M. et al. (2008). Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature 454, 221-225.
-
(2008)
Nature
, vol.454
, pp. 221-225
-
-
Bozec, A.1
Bakiri, L.2
Hoebertz, A.3
Eferl, R.4
Schilling, A.F.5
Komnenovic, V.6
Scheuch, H.7
Priemel, M.8
Stewart, C.L.9
Amling, M.10
-
5
-
-
77957189890
-
Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production
-
Bozec, A., Bakiri, L., Jimenez, M., Schinke, T., Amling, M. and Wagner, E. F. (2010). Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production. J. Cell Biol. 190, 1093-1106.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 1093-1106
-
-
Bozec, A.1
Bakiri, L.2
Jimenez, M.3
Schinke, T.4
Amling, M.5
Wagner, E.F.6
-
6
-
-
58749104432
-
Adiponectin is a negative regulator of bone mineral and bone strength in growing mice
-
Ealey, K. N., Kaludjerovic, J., Archer, M. C. and Ward, W. E. (2008). Adiponectin is a negative regulator of bone mineral and bone strength in growing mice. Exp. Biol. Med. 233, 1546-1553.
-
(2008)
Exp. Biol. Med.
, vol.233
, pp. 1546-1553
-
-
Ealey, K.N.1
Kaludjerovic, J.2
Archer, M.C.3
Ward, W.E.4
-
7
-
-
3543045594
-
The Fos-related antigen Fra-1 is an activator of bone matrix formation
-
Eferl, R., Hoebertz, A., Schilling, A. F., Rath, M., Karreth, F., Kenner, L., Amling, M. and Wagner, E. F. (2004). The Fos-related antigen Fra-1 is an activator of bone matrix formation. EMBO J. 23, 2789-2799.
-
(2004)
EMBO J.
, vol.23
, pp. 2789-2799
-
-
Eferl, R.1
Hoebertz, A.2
Schilling, A.F.3
Rath, M.4
Karreth, F.5
Kenner, L.6
Amling, M.7
Wagner, E.F.8
-
8
-
-
34547657339
-
Simultaneous generation of fra-2 conditional and fra-2 knock-out mice
-
Eferl, R., Zenz, R., Theussl, H. C. and Wagner, E. F. (2007). Simultaneous generation of fra-2 conditional and fra-2 knock-out mice. Genesis 45, 447-451.
-
(2007)
Genesis
, vol.45
, pp. 447-451
-
-
Eferl, R.1
Zenz, R.2
Theussl, H.C.3
Wagner, E.F.4
-
9
-
-
48749092428
-
Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1
-
Eferl, R., Hasselblatt, P., Rath, M., Popper, H., Zenz, R., Komnenovic, V., Idarraga, M. H., Kenner, L. and Wagner, E. F. (2008). Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1. Proc. Natl. Acad. Sci. USA 105, 10525-10530.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10525-10530
-
-
Eferl, R.1
Hasselblatt, P.2
Rath, M.3
Popper, H.4
Zenz, R.5
Komnenovic, V.6
Idarraga, M.H.7
Kenner, L.8
Wagner, E.F.9
-
10
-
-
79952155359
-
Transcriptional control of adipose lipid handling by IRF4
-
Eguchi, J., Wang, X., Yu, S., Kershaw, E. E., Chiu, P. C., Dushay, J., Estall, J. L., Klein, U., Maratos-Flier, E. and Rosen, E. D. (2011). Transcriptional control of adipose lipid handling by IRF4. Cell Metab. 13, 249-259.
-
(2011)
Cell Metab.
, vol.13
, pp. 249-259
-
-
Eguchi, J.1
Wang, X.2
Yu, S.3
Kershaw, E.E.4
Chiu, P.C.5
Dushay, J.6
Estall, J.L.7
Klein, U.8
Maratos-Flier, E.9
Rosen, E.D.10
-
11
-
-
34250679243
-
Effects of pronounced weight loss on adiponectin oligomer composition and metabolic parameters
-
Engl, J., Bobbert, T., Ciardi, C., Laimer, M., Tatarczyk, T., Kaser, S., Weiss, H., Molnar, C., Tilg, H., Patsch, J. R. et al. (2007). Effects of pronounced weight loss on adiponectin oligomer composition and metabolic parameters. Obesity 15, 1172- 1178.
-
(2007)
Obesity
, vol.15
-
-
Engl, J.1
Bobbert, T.2
Ciardi, C.3
Laimer, M.4
Tatarczyk, T.5
Kaser, S.6
Weiss, H.7
Molnar, C.8
Tilg, H.9
Patsch, J.R.10
-
12
-
-
42449096306
-
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
-
Ferron, M., Hinoi, E., Karsenty, G. and Ducy, P. (2008). Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc. Natl. Acad. Sci. USA 105, 5266-5270.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5266-5270
-
-
Ferron, M.1
Hinoi, E.2
Karsenty, G.3
Ducy, P.4
-
13
-
-
77955035304
-
Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
-
Ferron, M., Wei, J., Yoshizawa, T., Del Fattore, A., DePinho, R. A., Teti, A., Ducy, P. and Karsenty, G. (2010). Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell 142, 296-308.
-
(2010)
Cell
, vol.142
, pp. 296-308
-
-
Ferron, M.1
Wei, J.2
Yoshizawa, T.3
Del Fattore, A.4
DePinho, R.A.5
Teti, A.6
Ducy, P.7
Karsenty, G.8
-
14
-
-
84855866319
-
Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice
-
Ferron, M., McKee, M. D., Levine, R. L., Ducy, P. and Karsenty, G. (2012). Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice. Bone 50, 568-575.
-
(2012)
Bone
, vol.50
, pp. 568-575
-
-
Ferron, M.1
McKee, M.D.2
Levine, R.L.3
Ducy, P.4
Karsenty, G.5
-
15
-
-
0027236534
-
Osteoblasts are target cells for transformation in c-fos transgenic mice
-
Grigoriadis, A. E., Schellander, K., Wang, Z. Q. and Wagner, E. F. (1993). Osteoblasts are target cells for transformation in c-fos transgenic mice. J. Cell Biol. 122, 685-701.
-
(1993)
J. Cell Biol.
, vol.122
, pp. 685-701
-
-
Grigoriadis, A.E.1
Schellander, K.2
Wang, Z.Q.3
Wagner, E.F.4
-
16
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
Kadowaki, T., Yamauchi, T., Kubota, N., Hara, K., Ueki, K. and Tobe, K. (2006). Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
-
17
-
-
10344262559
-
The AP1 transcription factor Fra2 is required for efficient cartilage development
-
Karreth, F., Hoebertz, A., Scheuch, H., Eferl, R. and Wagner, E. F. (2004). The AP1 transcription factor Fra2 is required for efficient cartilage development. Development 131, 5717-5725.
-
(2004)
Development
, vol.131
, pp. 5717-5725
-
-
Karreth, F.1
Hoebertz, A.2
Scheuch, H.3
Eferl, R.4
Wagner, E.F.5
-
18
-
-
84855987634
-
The contribution of bone to whole-organism physiology
-
Karsenty, G. and Ferron, M. (2012). The contribution of bone to whole-organism physiology. Nature 481, 314-320.
-
(2012)
Nature
, vol.481
, pp. 314-320
-
-
Karsenty, G.1
Ferron, M.2
-
19
-
-
70349567378
-
Fat targets for skeletal health
-
Kawai, M., Devlin, M. J. and Rosen, C. J. (2009). Fat targets for skeletal health. Nat. Rev. Rheumatology 5, 365-372.
-
(2009)
Nat. Rev. Rheumatology
, vol.5
, pp. 365-372
-
-
Kawai, M.1
Devlin, M.J.2
Rosen, C.J.3
-
20
-
-
0036827527
-
The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels
-
Kveiborg, M., Chiusaroli, R., Sims, N. A., Wu, M., Sabatakos, G., Horne, W. C. and Baron, R. (2002). The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels. Endocrinology 143, 4304-4309.
-
(2002)
Endocrinology
, vol.143
, pp. 4304-4309
-
-
Kveiborg, M.1
Chiusaroli, R.2
Sims, N.A.3
Wu, M.4
Sabatakos, G.5
Horne, W.C.6
Baron, R.7
-
21
-
-
45349084061
-
Reciprocal regulation of bone and energy metabolism
-
Lee, N. K. and Karsenty, G. (2008). Reciprocal regulation of bone and energy metabolism. Trends Endocrinol. Metab.19, 161-166.
-
(2008)
Trends Endocrinol. Metab.
, vol.19
, pp. 161-166
-
-
Lee, N.K.1
Karsenty, G.2
-
22
-
-
34547690686
-
Endocrine regulation of energy metabolism by the skeleton
-
Lee, N. K., Sowa, H., Hinoi, E., Ferron, M., Ahn, J. D., Confavreux, C., Dacquin, R., Mee, P. J., McKee, M. D., Jung, D. Y. et al. (2007). Endocrine regulation of energy metabolism by the skeleton. Cell 130, 456-469.
-
(2007)
Cell
, vol.130
, pp. 456-469
-
-
Lee, N.K.1
Sowa, H.2
Hinoi, E.3
Ferron, M.4
Ahn, J.D.5
Confavreux, C.6
Dacquin, R.7
Mee, P.J.8
McKee, M.D.9
Jung, D.Y.10
-
23
-
-
70349974675
-
Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells
-
Lee, H. W., Kim, S. Y., Kim, A. Y., Lee, E. J., Choi, J. Y. and Kim, J. B. (2009). Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells. Stem Cells 27, 2254-2262.
-
(2009)
Stem Cells
, vol.27
, pp. 2254-2262
-
-
Lee, H.W.1
Kim, S.Y.2
Kim, A.Y.3
Lee, E.J.4
Choi, J.Y.5
Kim, J.B.6
-
25
-
-
79955531027
-
Elevated Fra-1 expression causes severe lipodystrophy
-
Luther, J., Driessler, F., Megges, M., Hess, A., Herbort, B., Mandic, V., Zaiss, M. M., Reichardt, A., Zech, C., Tuckermann, J. P. et al. (2011). Elevated Fra-1 expression causes severe lipodystrophy. J. Cell Sci. 124, 1465-1476.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 1465-1476
-
-
Luther, J.1
Driessler, F.2
Megges, M.3
Hess, A.4
Herbort, B.5
Mandic, V.6
Zaiss, M.M.7
Reichardt, A.8
Zech, C.9
Tuckermann, J.P.10
-
26
-
-
18044394024
-
Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast
-
Oshima, K., Nampei, A., Matsuda, M., Iwaki, M., Fukuhara, A., Hashimoto, J., Yoshikawa, H. and Shimomura, I. (2005). Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast. Biochem. Biophys. Res. Commun. 331, 520-526.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.331
, pp. 520-526
-
-
Oshima, K.1
Nampei, A.2
Matsuda, M.3
Iwaki, M.4
Fukuhara, A.5
Hashimoto, J.6
Yoshikawa, H.7
Shimomura, I.8
-
27
-
-
79952289069
-
Endocrine regulation of male fertility by the skeleton
-
Oury, F., Sumara, G., Sumara, O., Ferron, M., Chang, H., Smith, C. E., Hermo, L., Suarez, S., Roth, B. L., Ducy, P. et al. (2011). Endocrine regulation of male fertility by the skeleton. Cell 144, 796-809.
-
(2011)
Cell
, vol.144
, pp. 796-809
-
-
Oury, F.1
Sumara, G.2
Sumara, O.3
Ferron, M.4
Chang, H.5
Smith, C.E.6
Hermo, L.7
Suarez, S.8
Roth, B.L.9
Ducy, P.10
-
28
-
-
0023488581
-
Bone histomorphometry: standardization of nomenclature, symbols, and units
-
Report of the ASBMR Histomorphometry Nomenclature Committee
-
Parfitt, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. A., Malluche, H., Meunier, P. J., Ott, S. M., Recker, R. R.; Report of the ASBMR Histomorphometry Nomenclature Committee (1987). Bone histomorphometry: standardization of nomenclature, symbols, and units. J. Bone Miner. Res. 2, 595-610.
-
(1987)
J. Bone Miner. Res.
, vol.2
, pp. 595-610
-
-
Parfitt, A.M.1
Drezner, M.K.2
Glorieux, F.H.3
Kanis, J.A.4
Malluche, H.5
Meunier, P.J.6
Ott, S.M.7
Recker, R.R.8
-
29
-
-
75149115329
-
FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts
-
Rached, M. T., Kode, A., Xu, L., Yoshikawa, Y., Paik, J. H., Depinho, R. A. and Kousteni, S. (2010). FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts. Cell Metab. 11, 147- 160.
-
(2010)
Cell Metab.
, vol.11
-
-
Rached, M.T.1
Kode, A.2
Xu, L.3
Yoshikawa, Y.4
Paik, J.H.5
Depinho, R.A.6
Kousteni, S.7
-
30
-
-
33748768971
-
Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
-
Rodda, S. J. and McMahon, A. P. (2006). Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 133, 3231-3244.
-
(2006)
Development
, vol.133
, pp. 3231-3244
-
-
Rodda, S.J.1
McMahon, A.P.2
-
31
-
-
65349162789
-
Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies
-
Shetty, S., Kusminski, C. M. and Scherer, P. E. (2009). Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies. Trends Pharmacol. Sci. 30, 234-239.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 234-239
-
-
Shetty, S.1
Kusminski, C.M.2
Scherer, P.E.3
-
32
-
-
33748079106
-
Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways
-
Shinoda, Y., Yamaguchi, M., Ogata, N., Akune, T., Kubota, N., Yamauchi, T., Terauchi, Y., Kadowaki, T., Takeuchi, Y., Fukumoto, S. et al. (2006). Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. J. Cell. Biochem. 99, 196-208.
-
(2006)
J. Cell. Biochem.
, vol.99
, pp. 196-208
-
-
Shinoda, Y.1
Yamaguchi, M.2
Ogata, N.3
Akune, T.4
Kubota, N.5
Yamauchi, T.6
Terauchi, Y.7
Kadowaki, T.8
Takeuchi, Y.9
Fukumoto, S.10
-
33
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda, S., Elefteriou, F., Levasseur, R., Liu, X., Zhao, L., Parker, K. L., Armstrong, D., Ducy, P. and Karsenty, G. (2002). Leptin regulates bone formation via the sympathetic nervous system. Cell 111, 305-317.
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
Armstrong, D.7
Ducy, P.8
Karsenty, G.9
-
34
-
-
33748992313
-
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
-
Tilg, H. and Moschen, A. R. (2006). Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat. Rev. Immunol. 6, 772-783.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 772-783
-
-
Tilg, H.1
Moschen, A.R.2
-
35
-
-
28544434439
-
Fos/AP-1 proteins in bone and the immune system
-
Wagner, E. F. and Eferl, R. (2005). Fos/AP-1 proteins in bone and the immune system. Immunol. Rev. 208, 126-140.
-
(2005)
Immunol. Rev.
, vol.208
, pp. 126-140
-
-
Wagner, E.F.1
Eferl, R.2
-
36
-
-
67651148206
-
In vitro and in vivo effects of adiponectin on bone
-
Williams, G. A., Wang, Y., Callon, K. E., Watson, M., Lin, J. M., Lam, J. B., Costa, J. L., Orpe, A., Broom, N., Naot, D. et al. (2009). In vitro and in vivo effects of adiponectin on bone. Endocrinology 150, 3603-3610.
-
(2009)
Endocrinology
, vol.150
, pp. 3603-3610
-
-
Williams, G.A.1
Wang, Y.2
Callon, K.E.3
Watson, M.4
Lin, J.M.5
Lam, J.B.6
Costa, J.L.7
Orpe, A.8
Broom, N.9
Naot, D.10
-
37
-
-
84863229577
-
FOSL2 promotes leptin gene expression in human and mouse adipocytes
-
Wrann, C. D., Eguchi, J., Bozec, A., Xu, Z., Mikkelsen, T., Gimble, J., Nave, H., Wagner, E. F., Ong, S. E. and Rosen, E. D. (2012). FOSL2 promotes leptin gene expression in human and mouse adipocytes. J. Clin. Invest. 122, 1010-1021.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1010-1021
-
-
Wrann, C.D.1
Eguchi, J.2
Bozec, A.3
Xu, Z.4
Mikkelsen, T.5
Gimble, J.6
Nave, H.7
Wagner, E.F.8
Ong, S.E.9
Rosen, E.D.10
-
38
-
-
8744224520
-
ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells
-
Yang, X. and Karsenty, G. (2004). ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. J. Biol. Chem. 279, 47109- 47114.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Yang, X.1
Karsenty, G.2
-
39
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin- Lowry Syndrome
-
Yang, X., Matsuda, K., Bialek, P., Jacquot, S., Masuoka, H. C., Schinke, T., Li, L., Brancorsini, S., Sassone-Corsi, P., Townes, T. M. et al. (2004). ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin- Lowry Syndrome. Cell 117, 387-398.
-
(2004)
Cell
, vol.117
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
-
40
-
-
70349226800
-
The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
-
Yoshizawa, T., Hinoi, E., Jung, D. Y., Kajimura, D., Ferron, M., Seo, J., Graff, J. M., Kim, J. K. and Karsenty, G. (2009). The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. J. Clin. Invest. 119, 2807-2817.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2807-2817
-
-
Yoshizawa, T.1
Hinoi, E.2
Jung, D.Y.3
Kajimura, D.4
Ferron, M.5
Seo, J.6
Graff, J.M.7
Kim, J.K.8
Karsenty, G.9
-
41
-
-
37548998960
-
Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis
-
Zhao, L. J., Jiang, H., Papasian, C. J., Maulik, D., Drees, B., Hamilton, J. and Deng, H. W. (2008). Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J. Bone Miner. Res. 23, 17-29.
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 17-29
-
-
Zhao, L.J.1
Jiang, H.2
Papasian, C.J.3
Maulik, D.4
Drees, B.5
Hamilton, J.6
Deng, H.W.7
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