Isotope-labelled urea to test colon drug delivery devices in vivo: principles, calculations and interpretations

Isotopes in Environmental and Health Studies

Volumn 49, Issue 4, 2013, Pages 473-491

  Maurer, Marina J M ^a   Schellekens, Reinout C A ^a   Wutzke, Klaus D ^b   Stellaard, Frans ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

13C urea; 15N2 urea; bioavailability; carbon 13; colon delivery; health; human; isotope application in medicine; nitrogen 15; stable isotope tracer techniques

Indexed keywords

BIOAVAILABILITY; CARBON; CONCENTRATION (COMPOSITION); DRUG; EXPERIMENTAL STUDY; ISOTOPIC COMPOSITION; MEDICINE; TIME DEPENDENT BEHAVIOR; UREA;

CARBON; CARBON DIOXIDE; NITROGEN; UREA;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; BLOOD; BREATH ANALYSIS; COLON; DRUG DELIVERY SYSTEM; HUMAN; METABOLISM; URINE;

ALGORITHMS; BREATH TESTS; CARBON DIOXIDE; CARBON ISOTOPES; COLON; DRUG DELIVERY SYSTEMS; HUMANS; MODELS, BIOLOGICAL; NITROGEN ISOTOPES; UREA;

EID: 84890146139     PISSN: 10256016     EISSN: 14772639     Source Type: Journal    
DOI: 10.1080/10256016.2013.803099     Document Type: Article

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