Ammonia clearance with haemofiltration in adults with liver disease

Liver International

Volumn 34, Issue 1, 2014, Pages 42-48

  Slack, Andrew J ^a   Auzinger, Georg ^a   Willars, Chris ^a   Dew, Tracy ^a   Musto, Rebecca ^a   Corsilli, Daniel ^a   Sherwood, Roy ^a   Wendon, Julia A ^a   Bernal, William ^a  

^a KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Ammonia clearance; Cordoba equation; Haemofiltration; Hyperammonaemia; Ultrafiltration rate

Indexed keywords

AMMONIA; UREA;

ACUTE LIVER FAILURE; ADULT; AMMONIA BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTINUOUS RENAL REPLACEMENT THERAPY; HEMOFILTRATION; HUMAN; HYPERAMMONEMIA; INTERNATIONAL NORMALIZED RATIO; LIVER DISEASE; LIVER FAILURE; LIVER RESECTION; LIVER TRANSPLANTATION; PROSPECTIVE STUDY; ULTRAFILTRATION;

AMMONIA CLEARANCE; CORDOBA EQUATION; HAEMOFILTRATION; HYPERAMMONAEMIA; ULTRAFILTRATION RATE;

ADULT; AMMONIA; FEMALE; HEMODIAFILTRATION; HUMANS; HYPERAMMONEMIA; LIVER FAILURE; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; UREA;

EID: 84890128367     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12221     Document Type: Article

References (31)

1. Phillips GB, Schwartz R, Gabuzda GJ, Davidson CS. The syndrome of impending hepatic coma in patients with cirrhosis of the liver given certain nitrogenous substances. N Engl J Med 1952; 247: 239-46.
2. Wright G, Noiret L, Olde Damink SWM, Jalan R. Interorgan ammonia metabolism in liver failure: the basis of current and future therapies. Liver Int 2011; 31: 163-75.
3. Clemmesen JO, Larsen FS, Kondrup J, Hansen BA, Ott P. Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology 1999; 29: 648-53.
4. Bhatia V, Singh R, Acharya SK. Predictive value of arterial ammonia for complications and outcome in acute liver failure. Gut 2006; 55: 98-104.
5. Bernal W, Hall C, Karvellas CJ, et al. Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure. Hepatology 2007; 46: 1844-52.
6. Shawcross D, Jalan R. The pathophysiologic basis of hepatic encephalopathy: central role for ammonia and inflammation. Cell Mol Life Sci 2005; 62: 2295-304.
7. Vaquero J, Chung C, Cahill ME, Blei AT. Pathogenesis of hepatic encephalopathy in acute liver failure. Semin Liver Dis 2003; 23: 259-69.
8. Ching S, Rogoff TM, Gabuzda GJ. Renal ammoniagenesis and tissue glutamine, glutamine synthetase, and glutaminase I levels in potassium-deficient rats. J Lab Clin Med 1973; 82: 208-14.
9. Jalan R, Kapoor D. Reversal of diuretic-induced hepatic encephalopathy with infusion of albumin but not colloid. Clin Sci (Lond) 2004; 106: 467-74.
10. Kircheis G, Nilius R, Held C, et al. Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepatic encephalopathy: results of a placebo-controlled, double-blind study. Hepatology 1997; 25: 1351-60.
11. Blei AT, Cordoba J. Hepatic encephalopathy. Am J Gastroenterol 2001; 96: 1968-76.
12. Bucci L, Palmieri GC. Double-blind, double-dummy comparison between treatment with rifaximin and lactulose in patients with medium to severe degree hepatic encephalopathy. Curr Med Res Opin 1993; 13: 109-18.
13. Rose CF. Ammonia-lowering strategies for the treatment of hepatic encephalopathy. Clin Pharmacol Ther 2012; 92: 321-31.
14. Banares R, Nevens F, Larsen FS, et al. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology 2013; 57: 1153-62.
15. Arbeiter AK, Kranz B, Wingen A-M, et al. Continuous venovenous haemodialysis (CVVHD) and continuous peritoneal dialysis (CPD) in the acute management of 21 children with inborn errors of metabolism. Nephrol Dial Transplant 2010; 25: 1257-65.
16. Picca S, Bartuli A, Dionisi-Vici C. Medical management and dialysis therapy for the infant with an inborn error of metabolism. Semin Nephrol 2008; 28: 477-80.
17. Chan WK, But WM, Law CW. Ammonia detoxification by continuous venovenous haemofiltration in an infant with urea cycle defect. Hong Kong Med J 2002; 8: 207-10.
18. Lai YC, Huang H-P, Tsai IJ, Tsau Y-K. High-volume continuous venovenous hemofiltration as an effective therapy for acute management of inborn errors of metabolism in young children. Blood Purif 2007; 25: 303-8.
19. Cordoba J, Blei AT, Mujais S. Determinants of ammonia clearance by hemodialysis. Artif Organs 1996; 20: 800-3.
20. O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet 1993; 342: 273-5.
21. Ferenci P, Lockwood A, Mullen K, et al. Hepatic encephalopathy-definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 2002; 35: 716-21.
22. Wiegand C, Thompson T, Bock GH, et al. The management of life-threatening hyperammonemia: a comparison of several therapeutic modalities. J Pediatr 1980; 96: 142-4.
23. Bellomo R, Cass A, Cole L, et al. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 2009; 361: 1627-38.
24. Tapia P, Chinchon E, Morales D, Stehberg J, Simon F. Effectiveness of short-term 6-hour high-volume hemofiltration during refractory severe septic shock. J Trauma Acute Care Surg 2012; 72: 1228-37; discussion 1237-8.
25. Cornejo R, Downey P, Castro R, et al. High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock. Intensive Care Med 2006; 32: 713-22.
26. Honore PM, Jamez J, Wauthier M, et al. Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock. Crit Care Med 2000; 28: 3581-7.
27. Sadaka F, Veremakis C. Therapeutic hypothermia for the management of intracranial hypertension in severe traumatic brain injury: a systematic review. Brain Inj 2012; 26: 899-908.
28. Vaquero J, Butterworth RF. Mechanisms of brain edema in acute liver failure and impact of novel therapeutic interventions. Neurol Res 2007; 29: 683-90.
29. Gashti CN, Rodby RA, Huang Z, Gao D, Zhang W. Effects of high blood flow and high pre-dilution replacement fluid rates on small solute clearances in hemofiltration. Blood Purif 2011; 32: 266-70.
30. Huang Z, Letteri JJ, Clark WR, et al. Ultrafiltration rate as a dose surrogate in pre-dilution hemofiltration. Int J Artif Organs 2007; 30: 124-32.
31. Ricci Z, Ronco C, Bachetoni A, et al. Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion. Crit Care 2006; 10: R67.