Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion

World Journal of Gastroenterology

Volumn 17, Issue 2, 2011, Pages 254-259

  Zhang, Yan ^a   Leng, Yu Fang ^a   Xue, Xing ^a   Zhang, Yue ^a   Wang, Tao ^a   Kang, Yu Qing ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Limb ischemia reperfusion injury; Penehyelidine hydrochloride; Post conditioning; Protection; Small intestine

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); ENDOTOXIN; GASTROINTESTINAL MUCOSA PROTECTIVE AGENT; INTERLEUKIN 10; MYELOPEROXIDASE; PENEHYCLIDINE HYDROCHLORIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; COLORIMETRY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ACTIVITY; ILEOCECAL VALVE; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; INTESTINE MUCOSA PERMEABILITY; LIMB ISCHEMIA; LIMB ISCHEMIA REPERFUSION INJURY; LYMPH FOLLICLE; LYMPH VESSEL; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MALE; MICROSCOPY; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; RAT; REPERFUSION; SMALL INTESTINE MUCOSA; SPECTROPHOTOMETER;

EID: 79955763944     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i2.254     Document Type: Article

References (33)

1. Christ F, Moser CM, Niklas M, Gartside IB, Gamble J, Refor HJ, Peter K, Messmer K. Prevalence of cyclic changes in limb volume (volumotion) of male patients with knee injury and the effects of ischemia/reperfusion due to tourniquet. Int J Microcirc Clin Exp 1995; 15: 14-20
2. Mathru M, Dries DJ, Barnes L, Tonino P, Sukhani R, Rooney MW. Tourniquet-induced exsanguination in patients requiring lower limb surgery. An ischemia-reperfusion model of oxidant and antioxidant metabolism. Anesthesiology 1996; 84: 14-22
3. Soong CV, Blair PH, Halliday MI, McCaigue MD, Hood JM, Rowlands BJ, Barros D'SA. Bowel ischaemia and organ impairment in elective abdominal aortic aneurysm repair. Br J Surg 1994; 81: 965-968
4. Soong CV, Young IS, Lightbody JH, Hood JM, Rowlands BJ, Trimble ER, Barros D'Sa AA. Reduction of free radical generation minimises lower limb swelling following femoro-popliteal bypass surgery. Eur J Vasc Surg 1994; 8: 435-440
5. Wehrens XH, Rouwet EV, Oude Egbrink MG, Slaaf DW, Ramsay G. Effects of experimental lower-limb ischaemia-reperfusion injury on the mesenteric microcirculation. Br J Surg 2002; 89: 185-191
6. Annecke T, Kubitz JC, Kahr S, Hilberath JM, Langer K, Kemming GI, Rehm M, Bittmann I, Conzen PF. Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs. Br J Anaesth 2007; 98: 581-590
7. Cámara CR, Guzmán FJ, Barrera EA, Cabello AJ, Garcia A, Fernández NE, Caballero E, Ancer J. Ketamine anesthesia reduces intestinal ischemia/reperfusion injury in rats. World J Gastroenterol 2008; 14: 5192-5196
8. Chen Q, Zeng Y. Anisodamine protects against neuronal death following cerebral ischemia in gerbils. Chin Med J (Engl) 2000; 113: 636-639
9. Shen W, Gan J, Xu S, Jiang G, Wu H. Penehyclidine hydro-chloride attenuates LPS-induced acute lung injury involvement of NF-kappaB pathway. Pharmacol Res 2009; 60: 296-302
10. Wang LL, Zhan LY, Wu XJ, Xia ZY. Effects of penehyclidine hydrochloride on apoptosis of lung tissues in rats with traumatic acute lung injury. Chin J Traumatol 2010; 13: 15-19
11. Cai DS, Jin BB, Pei L, Jin Z. Protective effects of penehycli-dine hydrochloride on liver injury in a rat cardiopulmonary bypass model. Eur J Anaesthesiol 2010; 27: 824-828
12. Niu WZ, Zhao DL, Liu CG. The effects of a new cholinolytic--8018--and its optical isomers on the central muscarinic and nicotinic receptors. Arch Int Pharmacodyn Ther 1990; 304: 64-74
13. Han XY, Liu H, Liu CH, Wu B, Chen LF, Zhong BH, Liu KL. Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018). Bioorg Med Chem Lett 2005; 15: 1979-1982
14. Wolvekamp MC, de Bruin RW. Diamine oxidase: an overview of historical, biochemical and functional aspects. Dig Dis 1994; 12: 2-14
15. Kazmierczak SC, Robertson AF. Evaluation of a spectropho-tometric method for measurement of activity of diamine oxi-dase in newborn infants. Ann Clin Lab Sci 1992; 22: 155-161
16. Stechmiller JK, Treloar D, Allen N. Gut dysfunction in critically ill patients: a review of the literature. Am J Crit Care 1997; 6: 204-209
17. Demirkan A, Savaş B, Melli M. Endotoxin level in ischemia-reperfusion injury in rats: effect of glutamine pretreatment on endotoxin levels and gut morphology. Nutrition 2010; 26: 106-111
18. Defraigne JO, Pincemail J. Local and systemic consequences of severe ischemia and reperfusion of the skeletal muscle. Physiopathology and prevention. Acta Chir Belg 1998; 98: 176-186
19. Yassin MM, Barros D'Sa AA, Parks TG, McCaigue MD, Leggett P, Halliday MI, Rowlands BJ. Lower limb ischaemia-reperfusion injury alters gastrointestinal structure and function. Br J Surg 1997; 84: 1425-1429
20. Edrees WK, Lau LL, Young IS, Smye MG, Gardiner KR, Lee B, Hannon RJ, Soong CV. The effect of lower limb ischaemia-re-perfusion on intestinal permeability and the systemic infam-matory response. Eur J Vasc Endovasc Surg 2003; 25: 330-335
21. Yassin MM, Barros D'Sa AA, Parks TG, Soong CV, Halliday MI, McCaigue MD, Erwin PJ, Rowlands BJ. Lower limb isch-aemia-reperfusion injury causes endotoxaemia and endogenous antiendotoxin antibody consumption but not bacterial translocation. Br J Surg 1998; 85: 785-789
22. Corson RJ, Paterson IS, O'Dwyer ST, Rowland P, Kirkman E, Little RA, McCollum CN. Lower limb ischaemia and reperfu-sion alters gut permeability. Eur J Vasc Surg 1992; 6: 158-163
23. Mullane KM, Kraemer R, Smith B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods 1985; 14: 157-167
24. Deitch EA, Taylor M, Grisham M, Ma L, Bridges W, Berg R. Endotoxin induces bacterial translocation and increases xan-thine oxidase activity. J Trauma 1989; 29: 1679-1683
25. Droy-Lefaix MT, Drouet Y, Geraud G, Hosford D, Braquet P. Superoxide dismutase (SOD) and the PAF-antagonist (BN 52021) reduce small intestinal damage induced by ischemia-reperfusion. Free Radic Res Commun 1991; 12-13 Pt 2: 725-735
26. Röth E, Hejjel L, Jaberansari M, Jancso G. The role of free radicals in endogenous adaptation and intracellular signals. Exp Clin Cardiol 2004; 9: 13-16
27. Zhang R, Brennan ML, Shen Z, MacPherson JC, Schmitt D, Molenda CE, Hazen SL. Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of infammation. J Biol Chem 2002; 277: 46116-46122
28. Xue RL, He JX, Wang N, Yao FZ, Lv JR, Wu G. Relationship between transmembrane signal transduction pathway and DNA repair and the mechanism after global cerebral isch-emia-reperfusion in rats. Neurosci Bull 2009; 25: 115-121
29. Souza DG, Soares AC, Pinho V, Torloni H, Reis LF, Teixeira MM, Dias AA. Increased mortality and infammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury. Am J Pathol 2002; 160: 1755-1765
30. Lane JS, Todd KE, Lewis MP, Gloor B, Ashley SW, Reber HA, McFadden DW, Chandler CF. Interleukin-10 reduces the systemic inflammatory response in a murine model of intestinal ischemia/reperfusion. Surgery 1997; 122: 288-294
31. Souza DG, Guabiraba R, Pinho V, Bristow A, Poole S, Teix-eira MM. IL-1-driven endogenous IL-10 production protects against the systemic and local acute infammatory response following intestinal reperfusion injury. J Immunol 2003; 170: 4759-4766
32. Souza DG, Teixeira MM. The balance between the production of tumor necrosis factor-alpha and interleukin-10 determines tissue injury and lethality during intestinal ischemia and reperfusion. Mem Inst Oswaldo Cruz 2005; 100 Suppl 1: 59-66
33. Chen LW, Egan L, Li ZW, Greten FR, Kagnoff MF, Karin M. The two faces of IKK and NF-kappaB inhibition: prevention of systemic infammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003; 9: 575-581