메뉴 건너뛰기




Volumn 63, Issue 1, 2014, Pages 112-119

The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP1) expression

Author keywords

Atherosclerosis; Dyslipidemia; PDE3; PPAR

Indexed keywords

APOLIPOPROTEIN E3; CILOSTAZOL; GLUCOSE TRANSPORTER 4; LIVER PROTEIN; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR; SMALL INTERFERING RNA; TRIACYLGLYCEROL;

EID: 84890115520     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.09.006     Document Type: Article
Times cited : (22)

References (32)
  • 1
    • 0033754497 scopus 로고    scopus 로고
    • A comparison of cilostazol and pentoxifylline for treating intermittent claudication
    • D.L. Dawson, B.S. Cutler, and W.R. Hiatt A comparison of cilostazol and pentoxifylline for treating intermittent claudication Am J Med 109 7 2000 523 530
    • (2000) Am J Med , vol.109 , Issue.7 , pp. 523-530
    • Dawson, D.L.1    Cutler, B.S.2    Hiatt, W.R.3
  • 2
    • 0032544181 scopus 로고    scopus 로고
    • Cilostazol has beneficial effects in treatment of intermittent claudication: Results from a multicenter, randomized, prospective, double-blind trial
    • D.L. Dawson, B.S. Cutler, and M.H. Meissner Cilostazol has beneficial effects in treatment of intermittent claudication: results from a multicenter, randomized, prospective, double-blind trial Circulation 98 7 1998 678 686
    • (1998) Circulation , vol.98 , Issue.7 , pp. 678-686
    • Dawson, D.L.1    Cutler, B.S.2    Meissner, M.H.3
  • 3
    • 0031929569 scopus 로고    scopus 로고
    • Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease
    • discussion 74-5
    • S.R. Money, J.A. Herd, and J.L. Isaacsohn Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease J Vasc Surg 27 2 1998 267 274 discussion 74-5
    • (1998) J Vasc Surg , vol.27 , Issue.2 , pp. 267-274
    • Money, S.R.1    Herd, J.A.2    Isaacsohn, J.L.3
  • 4
    • 0031649108 scopus 로고    scopus 로고
    • Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication
    • M.B. Elam, J. Heckman, and J.R. Crouse Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication Arterioscler Thromb Vasc Biol 18 12 1998 1942 1947
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , Issue.12 , pp. 1942-1947
    • Elam, M.B.1    Heckman, J.2    Crouse, J.R.3
  • 5
    • 0344741545 scopus 로고    scopus 로고
    • Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication
    • T. Wang, M.B. Elam, and W.P. Forbes Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication Atherosclerosis 171 2 2003 337 342
    • (2003) Atherosclerosis , vol.171 , Issue.2 , pp. 337-342
    • Wang, T.1    Elam, M.B.2    Forbes, W.P.3
  • 6
    • 0034836428 scopus 로고    scopus 로고
    • LRP: A multifunctional scavenger and signaling receptor
    • J. Herz, and D.K. Strickland LRP: a multifunctional scavenger and signaling receptor J Clin Invest 108 6 2001 779 784
    • (2001) J Clin Invest , vol.108 , Issue.6 , pp. 779-784
    • Herz, J.1    Strickland, D.K.2
  • 7
    • 0032004972 scopus 로고    scopus 로고
    • Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
    • A. Rohlmann, M. Gotthardt, and R.E. Hammer Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants J Clin Invest 101 3 1998 689 695
    • (1998) J Clin Invest , vol.101 , Issue.3 , pp. 689-695
    • Rohlmann, A.1    Gotthardt, M.2    Hammer, R.E.3
  • 8
    • 0029079403 scopus 로고
    • Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo
    • T.E. Willnow, S.A. Armstrong, and R.E. Hammer Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo Proc Natl Acad Sci U S A 92 10 1995 4537 4541
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.10 , pp. 4537-4541
    • Willnow, T.E.1    Armstrong, S.A.2    Hammer, R.E.3
  • 9
    • 0028284556 scopus 로고
    • Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
    • T.E. Willnow, Z. Sheng, and S. Ishibashi Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist Science 264 5164 1994 1471 1474
    • (1994) Science , vol.264 , Issue.5164 , pp. 1471-1474
    • Willnow, T.E.1    Sheng, Z.2    Ishibashi, S.3
  • 10
    • 50349092250 scopus 로고    scopus 로고
    • LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
    • A.P. Lillis, L.B. Van Duyn, and J.E. Murphy-Ullrich LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies Physiol Rev 88 3 2008 887 918
    • (2008) Physiol Rev , vol.88 , Issue.3 , pp. 887-918
    • Lillis, A.P.1    Van Duyn, L.B.2    Murphy-Ullrich, J.E.3
  • 11
    • 70350220516 scopus 로고    scopus 로고
    • Remnant lipoproteins as strong key particles to atherogenesis
    • Y. Fujioka, and Y. Ishikawa Remnant lipoproteins as strong key particles to atherogenesis J Atheroscler Thromb 16 3 2009 145 154
    • (2009) J Atheroscler Thromb , vol.16 , Issue.3 , pp. 145-154
    • Fujioka, Y.1    Ishikawa, Y.2
  • 12
    • 56649095559 scopus 로고    scopus 로고
    • Cilostazol increases 3T3-L1 preadipocyte differentiation with improved glucose uptake associated with activation of peroxisome proliferator-activated receptor-gamma transcription
    • S.Y. Park, J.H. Lee, and K.Y. Kim Cilostazol increases 3T3-L1 preadipocyte differentiation with improved glucose uptake associated with activation of peroxisome proliferator-activated receptor-gamma transcription Atherosclerosis 201 2 2008 258 265
    • (2008) Atherosclerosis , vol.201 , Issue.2 , pp. 258-265
    • Park, S.Y.1    Lee, J.H.2    Kim, K.Y.3
  • 13
    • 0033215570 scopus 로고    scopus 로고
    • Thymopoietin protein: From thymic hormone to proteins involved in nuclear architecture and cell cycle control
    • R. Herzano, and A.J. Simon Thymopoietin protein: from thymic hormone to proteins involved in nuclear architecture and cell cycle control Harefuah 137 7-8 1999 327 332
    • (1999) Harefuah , vol.137 , Issue.78 , pp. 327-332
    • Herzano, R.1    Simon, A.J.2
  • 14
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited FASEB J 22 3 2008 659 661
    • (2008) FASEB J , vol.22 , Issue.3 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 15
    • 0038823590 scopus 로고    scopus 로고
    • Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma
    • A. Gauthier, G. Vassiliou, and F. Benoist Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma J Biol Chem 278 14 2003 11945 11953
    • (2003) J Biol Chem , vol.278 , Issue.14 , pp. 11945-11953
    • Gauthier, A.1    Vassiliou, G.2    Benoist, F.3
  • 16
    • 0018800929 scopus 로고
    • Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts
    • T.L. Innerarity, R.E. Pitas, and R.W. Mahley Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts J Biol Chem 254 10 1979 4186 4190
    • (1979) J Biol Chem , vol.254 , Issue.10 , pp. 4186-4190
    • Innerarity, T.L.1    Pitas, R.E.2    Mahley, R.W.3
  • 18
    • 0021849433 scopus 로고
    • Effect of cilostazol on platelet aggregation and experimental thrombosis
    • Y. Kimura, T. Tani, and T. Kanbe Effect of cilostazol on platelet aggregation and experimental thrombosis Arzneimittelforschung 35 7A 1985 1144
    • (1985) Arzneimittelforschung , vol.35 , Issue.7 , pp. 1144
    • Kimura, Y.1    Tani, T.2    Kanbe, T.3
  • 19
    • 0141885183 scopus 로고    scopus 로고
    • Cilostazol as a unique antithrombotic agent
    • J. Kambayashi, Y. Liu, and B. Sun Cilostazol as a unique antithrombotic agent Curr Pharm Des 9 28 2003 2289 2302
    • (2003) Curr Pharm des , vol.9 , Issue.28 , pp. 2289-2302
    • Kambayashi, J.1    Liu, Y.2    Sun, B.3
  • 20
    • 0024406324 scopus 로고
    • Effect of cilostazol (Pletaal) on serum lipid levels in diabetic patients
    • E. Takazakura, K. Ohsawa, and K. Hamamatsu Effect of cilostazol (Pletaal) on serum lipid levels in diabetic patients Jpn Pharmacol Ther 17 1989 311 315
    • (1989) Jpn Pharmacol Ther , vol.17 , pp. 311-315
    • Takazakura, E.1    Ohsawa, K.2    Hamamatsu, K.3
  • 21
    • 0034530972 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase a activators
    • G. Lazennec, L. Canaple, and D. Saugy Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase a activators Mol Endocrinol 14 12 2000 1962 1975
    • (2000) Mol Endocrinol , vol.14 , Issue.12 , pp. 1962-1975
    • Lazennec, G.1    Canaple, L.2    Saugy, D.3
  • 22
    • 0037427520 scopus 로고    scopus 로고
    • Regulation of PPAR gamma transcriptional activity in 3T3-L1 adipocytes
    • M. Watanabe, K. Inukai, and H. Katagiri Regulation of PPAR gamma transcriptional activity in 3T3-L1 adipocytes Biochem Biophys Res Commun 300 2 2003 429 436
    • (2003) Biochem Biophys Res Commun , vol.300 , Issue.2 , pp. 429-436
    • Watanabe, M.1    Inukai, K.2    Katagiri, H.3
  • 23
    • 0025940314 scopus 로고
    • Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein
    • U. Beisiegel, W. Weber, and G. Bengtsson-Olivecrona Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein Proc Natl Acad Sci 88 19 1991 8342
    • (1991) Proc Natl Acad Sci , vol.88 , Issue.19 , pp. 8342
    • Beisiegel, U.1    Weber, W.2    Bengtsson-Olivecrona, G.3
  • 24
    • 67349108867 scopus 로고    scopus 로고
    • Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance
    • A. Laatsch, M. Merkel, and P.J. Talmud Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance Atherosclerosis 204 1 2009 105 111
    • (2009) Atherosclerosis , vol.204 , Issue.1 , pp. 105-111
    • Laatsch, A.1    Merkel, M.2    Talmud, P.J.3
  • 25
    • 79959361457 scopus 로고    scopus 로고
    • Up-regulation of hepatic low-density lipoprotein receptor-related protein 1: A possible novel mechanism of antiatherogenic activity of hydroxymethylglutaryl-coenzyme a reductase inhibitor atorvastatin and hepatic LRP1 expression
    • J.H. Moon, S.B. Kang, and J.S. Park Up-regulation of hepatic low-density lipoprotein receptor-related protein 1: a possible novel mechanism of antiatherogenic activity of hydroxymethylglutaryl-coenzyme a reductase inhibitor atorvastatin and hepatic LRP1 expression Metabolism 60 7 2011 930 940
    • (2011) Metabolism , vol.60 , Issue.7 , pp. 930-940
    • Moon, J.H.1    Kang, S.B.2    Park, J.S.3
  • 26
    • 84867910005 scopus 로고    scopus 로고
    • Upregulation of hepatic LRP1 by rosiglitazone: A possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia
    • J.H. Moon, H.J. Kim, and H.M. Kim Upregulation of hepatic LRP1 by rosiglitazone: a possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia J Mol Endocrinol 49 3 2012 165 174
    • (2012) J Mol Endocrinol , vol.49 , Issue.3 , pp. 165-174
    • Moon, J.H.1    Kim, H.J.2    Kim, H.M.3
  • 27
    • 79953861192 scopus 로고    scopus 로고
    • Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice
    • J.E. Basford, L. Wancata, and S.M. Hofmann Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice J Biol Chem 286 15 2011 13079 13087
    • (2011) J Biol Chem , vol.286 , Issue.15 , pp. 13079-13087
    • Basford, J.E.1    Wancata, L.2    Hofmann, S.M.3
  • 28
    • 64949096705 scopus 로고    scopus 로고
    • The vascular and biochemical effects of cilostazol in patients with peripheral arterial disease
    • M.E. O'Donnell, S.A. Badger, and M.A. Sharif The vascular and biochemical effects of cilostazol in patients with peripheral arterial disease J Vasc Surg 49 5 2009 1226 1234
    • (2009) J Vasc Surg , vol.49 , Issue.5 , pp. 1226-1234
    • O'Donnell, M.E.1    Badger, S.A.2    Sharif, M.A.3
  • 29
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein e
    • S.H. Zhang, R.L. Reddick, and J.A. Piedrahita Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E Science 258 5081 1992 468 471
    • (1992) Science , vol.258 , Issue.5081 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3
  • 30
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • A.S. Plump, J.D. Smith, and T. Hayek Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells Cell 71 2 1992 343 353
    • (1992) Cell , vol.71 , Issue.2 , pp. 343-353
    • Plump, A.S.1    Smith, J.D.2    Hayek, T.3
  • 31
    • 0027976942 scopus 로고
    • Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression
    • R.L. Reddick, S.H. Zhang, and N. Maeda Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression Arterioscler Thromb 14 1 1994 141 147
    • (1994) Arterioscler Thromb , vol.14 , Issue.1 , pp. 141-147
    • Reddick, R.L.1    Zhang, S.H.2    Maeda, N.3
  • 32
    • 0033821449 scopus 로고    scopus 로고
    • Cilostazol, a selective type iii phosphodiesterase inhibitor, decreases triglyceride and increases HDL cholesterol levels by increasing lipoprotein lipase activity in rats
    • T. Tani, K. Uehara, and T. Sudo Cilostazol, a selective type iii phosphodiesterase inhibitor, decreases triglyceride and increases HDL cholesterol levels by increasing lipoprotein lipase activity in rats Atherosclerosis 152 2 2000 299 305
    • (2000) Atherosclerosis , vol.152 , Issue.2 , pp. 299-305
    • Tani, T.1    Uehara, K.2    Sudo, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.