Pulmonary ultrashort echo time 19F MR imaging with inhaled fluorinated gas mixtures in healthy volunteers: Feasibility

Radiology

Volumn 269, Issue 3, 2013, Pages 903-909

  Couch, Marcus J ^a,b   Ball, Iain K ^a   Li, Tao ^a,b   Fox, Matthew S ^a   Littlefield, Shalyn L ^a   Biman, Birubi ^c,d,e   Albert, Mitchell S ^a,b  

^a Thunder Bay Regional Research Institute   (Canada)

^b LAKEHEAD UNIVERSITY   (Canada)

^c THUNDER BAY REGIONAL HEALTH SCIENCES CENTRE   (Canada)

^d NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORINE; OXYGEN; PERFLUTREN;

ADULT; ARTICLE; BREATH HOLDING; CONTROLLED STUDY; FEASIBILITY STUDY; FEMALE; HUMAN; INTERMETHOD COMPARISON; LUNG VENTILATION; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PRIORITY JOURNAL; SIGNAL NOISE RATIO; THREE DIMENSIONAL IMAGING; ULTRASHORT ECHO TIME MAGNETIC RESONANCE IMAGING; YOUNG ADULT;

ADULT; FEASIBILITY STUDIES; FEMALE; FLUORINE; FLUOROCARBONS; HUMANS; IMAGE ENHANCEMENT; IMAGING, THREE-DIMENSIONAL; LUNG; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; SIGNAL-TO-NOISE RATIO;

EID: 84890069600     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.13130609     Document Type: Article

References (22)

1. Jemal A, Ward E, Hao YP, Thun M. Trends in the leading causes of death in the United States, 1970-2002. JAMA 2005;294(10): 1255-1259.
2. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005;26(2):319-338.
3. Mills GH, Wild JM, Eberle B, Van Beek EJ. Functional magnetic resonance imaging of the lung. Br J Anaesth 2003;91(1): 16-30.
4. Johnson KM, Fain SB, Schiebler ML, Nagle S. Optimized 3D ultrashort echo time pulmonary MRI. Magn Reson Med 2012 Dec 4. [Epub ahead of print]
5. Ohno Y, Chen Q, Hatabu H. Oxygenenhanced magnetic resonance ventilation imaging of lung. Eur J Radiol 2001;37(3): 164-171.
6. Albert MS, Cates GD, Driehuys B, et al. Biological magnetic resonance imaging using laserpolarized 129Xe. Nature 1994;370(6486): 199-201.
7. Altes TA, Salerno M. Hyperpolarized gas MR imaging of the lung. J Thorac Imaging 2004; 19(4):250-258.
8. Kuethe DO, Caprihan A, Fukushima E, Waggoner RA. Imaging lungs using inert fluorinated gases. Magn Reson Med 1998; 39(1):85-88.
9. Schreiber WG, Eberle B, Laukemper- Ostendorf S, et al. Dynamic (19)F-MRI of pulmonary ventilation using sulfur hexafluoride (SF(6)) gas. Magn Reson Med 2001; 45(4):605-613.
10. Kuethe DO, Behr VC, Begay S. Volume of rat lungs measured throughout the respiratory cycle using 19F NMR of the inert gas SF6. Magn Reson Med 2002;48(3):547-549.
11. Kuethe DO, Caprihan A, Gach HM, Lowe IJ, Fukushima E. Imaging obstructed ventilation with NMR using inert fluorinated gases. J Appl Physiol 2000;88(6):2279-2286.
12. Adolphi NL, Kuethe DO. Quantitative mapping of ventilation-perfusion ratios in lungs by 19F MR imaging of T1 of inert fluorinated gases. Magn Reson Med 2008;59(4):739-746.
13. Wolf U, Scholz A, Heussel CP, Markstaller K, Schreiber WG. Subsecond fluorine- 19 MRI of the lung. Magn Reson Med 2006;55(4):948-951.
14. Scholz AW, Wolf U, Fabel M, et al. Comparison of magnetic resonance imaging of inhaled SF6 with respiratory gas analysis. Magn Reson Imaging 2009;27(4): 549-556.
15. Ruiz-Cabello J, Pérez-Sánchez JM, Pérez de Alejo R, et al. Diffusion-weighted 19F-MRI of lung periphery: influence of pressure and air-SF6 composition on apparent diffusion coefficients. Respir Physiol Neurobiol 2005; 148(1-2):43-56.
16. Pérez-Sánchez JM, Pérez de Alejo R, Rodríguez I, Cortijo M, Peces-Barba G, Ruiz-Cabello J. In vivo diffusion weighted 19F MRI using SF6. Magn Reson Med 2005;54(2): 460-463.
17. Carrero-González L, Kaulisch T, Stiller D. In vivo diffusion-weighted MRI using perfluorinated gases: ADC comparison between healthy and elastase-treated rat lungs. Magn Reson Med 2013 Feb 14.[Epub ahead of print]
18. Jacob RE, Chang YV, Choong CK, et al. 19F MR imaging of ventilation and diffusion in excised lungs. Magn Reson Med 2005; 54(3):577-585.
19. Conradi MS, Saam BT, Yablonskiy DA, Woods JC. Hyperpolarized 3He and perfluorocarbon gas diffusion MRI of lungs. Prog Nucl Magn Reson Spectrosc 2006;48(1): 63-83.
20. Soher BJ, Ainslie M, MacFall J, Hashoian R, Charles HC. Lung imaging in humans at 3T using perfluorinated gases as MR contrast agents [abstr]. In: Proceedings of the Eighteenth Meeting of the International Society for Magnetic Resonance in Medicine. Berkeley, Calif: International Society for Magnetic Resonance in Medicine, 2010; 3389.
21. Chang YV, Conradi MS. Relaxation and diffusion of perfluorocarbon gas mixtures with oxygen for lung MRI. J Magn Reson 2006;181(2):191-198.
22. West JB. Pulmonary pathophysiology. 8th ed. Baltimore, Md: Lippincott Williams & Wilkins, 2013.