19F MR imaging of ventilation and diffusion in excised lungs

Magnetic Resonance in Medicine

Volumn 54, Issue 3, 2005, Pages 577-585

  Jacob, Richard E ^a,b   Chang, Yulin V ^a   Choong, Cliff K ^a   Bierhals, Andy ^b   Hu, Ding Zheng ^a   Zheng, Jie ^b   Yablonskiy, Dmitriy A ^a,b   Woods, Jason C ^a,b   Gierada, David S ^b   Conradi, Mark S ^a,b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diffusion; Hyperpolarized gas; Lung; Perfluorinated gas

Indexed keywords

BIOLOGICAL ORGANS; DIFFUSION; INERT GASES; MAGNETIC RESONANCE IMAGING; SIGNAL TO NOISE RATIO; SPIN POLARIZATION; SURFACE DIFFUSION;

APPARENT DIFFUSION COEFFICIENT; HYPERPOLARIZED; IN-VIVO MEASUREMENT; LUNG; LUNG MICROSTRUCTURES; QUANTITATIVE CHARACTERIZATION; SURFACE-TO-VOLUME RATIO; SUSCEPTIBILITY ARTIFACTS;

SPIN DYNAMICS;

FLUORINE; HELIUM; PERFLUORO COMPOUND; ISOTOPE;

ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DOG; EMPHYSEMA; HUMAN; HUMAN TISSUE; IMAGING SYSTEM; LUNG; MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHANTOM; RADIOFREQUENCY; SIGNAL NOISE RATIO; ANIMAL; COMPARATIVE STUDY; DIFFUSION WEIGHTED IMAGING; IMAGE QUALITY; IN VITRO STUDY; LUNG DIFFUSION CAPACITY; LUNG EMPHYSEMA; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; DIFFUSION MAGNETIC RESONANCE IMAGING; DOGS; FLUORINE RADIOISOTOPES; HELIUM; HUMANS; ISOTOPES; PHANTOMS, IMAGING; PULMONARY DIFFUSING CAPACITY; PULMONARY EMPHYSEMA;

EID: 24144432287     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.20632     Document Type: Article

References (33)

1. 3He gas production and MR imaging of the lung. Concepts Magn Reson 2001;13:277-293.
2. Möller HE, Chen XJ, Saam B, Hagspiel KD, Johnson GA, Altes TA, de Lange EE, Kauczor HU. MRI of the lungs using hyperpolarized noble gases. Magn Reson Med 2002;47:1029-1051.
3. 3He MR lung ventilation imaging in asthmatics: preliminary findings. J Magn Reson Imaging 2001;13:378-384.
4. Donnelly LF, MacFall JR, McAdams HP, Majure JM, Smith J, Frush DP, Bogonad P, Charles HC, Ravin CE. Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung-preliminary observations. Radiology 1999;212:885-889.
5. West JB. Pulmonary pathophysiology. Baltimore: Williams and Wilkins; 1992. p 219.
6. 3He gas in healthy and diseased lungs. Magn Reson Med 2000;44:174-179.
7. Yablonskiy DA, Sukstanskii AL, Leawoods JC, Gierada DS, Bretthorst GL, Lefrak SS, Cooper JD, Conradi MS. Quantative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI. Proc Natl Acad Sci U.S.A. 2002;99:3111-3116.
8. Kuethe DO, Caprahan A, Fukushima E, Waggoner RA. Imaging lungs using inert fluorinated gases. Magn Reson Med 1998;38:85-88.
9. 6) gas. Magn Reson Med 2001;45:605-613.
10. Beyea SD, Codd SL, Kuethe DO, Fukushima E. Studies of porous media by thermally polarized gas NMR: current status. Magn Reson Imaging 2003;21:201-205.
11. Rinck PA, Peterson SB, Lauterbur PC. NMR-imaging von fluorhaltigen Substanzen. Fortschr Röntgenstr 1984;140:239-243.
12. Lizak M, Conradi MS, Fry CG. NMR imaging of gas imbibed into porous ceramic. J Magn Reson 1991;95:548-557.
13. 2. Phys Rev A 1995;52:862-864.
14. Miller KW, Paton WDM, Smith EB, Smith RA. Physicochemical approaches to the mode of action of general anesthetics. Anesthesiology 1972;36:339-351.
15. Courtney JA, Armstrong RL. A nuclear spin relaxation study of the spin-rotation interaction in spherical top molecules. Can J Phys 1972; 50:1252-1261.
16. Zielinski LJ, Sen PN. Effects of finite-width pulses in the pulsed-fleld gradient measurement of the diffusion coefficient in connected porous media. J Magn Reson 2003;165:153-161.
17. Coxson HO, Rogers RM, Whittall KP, D'yachkova Y, Paré PD, Sciurba FC, Hogg JC. A quantification of the lung surface area in emphysema using computed tomography. Am J Respir Crit Care Med 1999;159:851-856.
18. Bear J. Dynamics of fluids in porous media. New York: Amican Elsevier; 1972.
19. Salerno M, Brookeman JR, Mugler III JP, Time-dependent hyperpolarized 3He diffusion MR imaging: initial experience in healthy and emphysematous lungs. Proc Intl Soc Magn Reson Med 2001;9950.
20. Mitra PP, Sen PN, Schwartz LM. Short-time behavior of the diffusion coefficient as a geometrical probe of porous media. Phys Rev B 1993; 47:8565-8574.
21. de Swiet TM, Sen PN. Decay of nuclear magnetization by bounded diffusion in a constant field gradient. J Chem Phys 1994;100:5597-5604.
22. Conradi MS, Bruns MA, Sukstanskii AL, Gross SS, Leawoods JC. Feasibility of diffusion-NMR surface-to-volume measurements tested by calculations and computer simulations. J Magn Reson 2004;169:196-202.
23. Walker TG, Happer W. Spin-exchange optical pumping of noble-gas nuclei. Rev Mod Phys 1997;69:629-642.
24. 3He spin exchange cells for magnetic resonance imaging. J Appl Phys 2002;92:1588-1597.
25. Gotoh M, Okamoto T, Yamamoto Y, Liu D, Kameyama K, Hayashi E, Huang CL, Yokomise H. Development of a canine model of pulmonary emphysema and imaging of the emphysematous lung with infrared thoracoscopy. J Thorac Cardiovasc Surg 2003;126:1916-1921.
26. Wright BM, Slavin G, Kreel L, Callan K, Sandin B. Postmortem inflation and fixation of human lungs. Thorax 1974;29:189-194.
27. Mittermayer CH, Wybitul K, Rau WS, Ostendorf P, Reide UN. Standardized fixation of human lung for radiology and morphometry; description of a "two chamber"-system with formaldehyde vapor inflation. Path Res Pract 1978;162:115-130.
28. Mattiello J, Basser PJ, LeBihan D. Analytical expressions for the b matrix in NMR diffusion imaging and spectroscopy. J Magn Reson A 1994;108:131-141.
29. 6. NMR Biomed 2000;13:229-233.
30. 1 images of inert fluorinated gases in lungs. 7th International Conference on Magnetic Resonance Microscopy, Snowbird, UT, USA, 2003.
31. Saam B, Yablonskiy DA, Gierada DS, Conradi MS. Rapid imaging of hyperpolarized gas using EPI. Magn Reson Med 1999;42:507-514.
32. Kuethe DO, Caprihan A, Gach HM, Lowe IJ, Fukushima E. Imaging obstructed ventilation with NMR using inert fluorinated gases. J Appl Physiol 2000;88:2279-2286.
33. U.S. Food and Drug Administration. Criteria for significant risk investigations of magnetic resonance diagnostic devices. Center for Devices and Radiological Health document 2003. p 793.