Cold-induced activity of brown adipose tissue in young lean men of South-Asian and European origin

Diabetologia

Volumn 56, Issue 10, 2013, Pages 2231-2237

  Admiraal, W M ^a   Verberne, H J ^a   Karamat, F A ^a   Soeters, M R ^a   Hoekstra, J B L ^a   Holleman, F ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Brown adipose tissue; Ethnicity

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; FLUORODEOXYGLUCOSE F 18; (3 IODOBENZYL)GUANIDINE;

ADRENERGIC STIMULATION; ADULT; ARTICLE; BODY MASS; BROWN ADIPOSE TISSUE; COLD EXPOSURE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; ETHNIC DIFFERENCE; ETHNICITY; EUROPE; HUMAN; HUMAN EXPERIMENT; INSULIN SENSITIVITY; LEAN BODY WEIGHT; MALE; METABOLIC DISORDER; METABOLIC PARAMETERS; NORMAL HUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOUTH ASIA; STANDARDIZED UPTAKE VALUE; STEADY STATE; YOUNG ADULT; ADOLESCENT; ADRENERGIC SYSTEM; ASIA; COLD; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; DIET RESTRICTION; ETHNIC GROUP; ETHNOLOGY; GLUCOSE CLAMP TECHNIQUE; INNERVATION; INSULIN RESISTANCE; METABOLISM; PHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PROCEDURES;

3-IODOBENZYLGUANIDINE; ADIPOSE TISSUE, BROWN; ADOLESCENT; ADULT; ASIA; BODY MASS INDEX; COLD TEMPERATURE; ETHNIC GROUPS; EUROPE; FASTING; FLUORODEOXYGLUCOSE F18; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN RESISTANCE; MALE; POSITRON-EMISSION TOMOGRAPHY; SYMPATHETIC NERVOUS SYSTEM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 84890064639     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2938-5     Document Type: Article

References (24)

1. Chowdhury TA, Grace C, Kopelman PG (2003) Preventing diabetes in south Asians. BMJ 327:1059-1060
2. Gholap N, Davies M, Patel K, Sattar N, Khunti K (2011) Type 2 diabetes and cardiovascular disease in South Asians. Prim Care Diabetes 5:45-56
3. Oldroyd J, Banerjee M, Heald A, Cruickshank K (2005) Diabetes and ethnic minorities. Postgrad Med J 81:486-490
4. Samanta A, Burden AC, Fent B (1987) Comparative prevalence of non-insulin-dependent diabetes mellitus in Asian and white Caucasian adults. Diabetes Res Clin Pract 4:1-6
5. Whincup PH, Gilg JA, Papacosta O et al (2002) Early evidence of ethnic differences in cardiovascular risk: cross sectional comparison of British South Asian and white children. BMJ 324:635
6. Cypess AM, Lehman S, Williams G et al (2009) Identification and importance of brown adipose tissue in adult humans. N Engl J Med 360:1509-1517
7. Nedergaard J, Bengtsson T, Cannon B (2007) Unexpected evidence for active brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab 293:E444-E452
8. van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM et al (2009) Cold-activated brown adipose tissue in healthy men. N Engl J Med 360:1500-1508
9. Virtanen KA, Lidell ME, Orava J et al (2009) Functional brown adipose tissue in healthy adults. N Engl J Med 360:1518-1525
10. Cronin CG, Prakash P, Daniels GH et al (2012) Brown fat at PET/CT: correlation with patient characteristics. Radiology 263:836-842
11. Raji A, Gerhard-Herman MD, Warren M et al (2004) Insulin resistance and vascular dysfunction in nondiabetic Asian Indians. J Clin Endocrinol Metab 89:3965-3972
12. Enerback S (2010) Human brown adipose tissue. Cell Metab 11:248-252
13. Admiraal WM, Holleman F, Bahler L, Soeters MR, Hoekstra JB, Verberne HJ (2013) Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure. J Nucl Med 54:208-212
14. Abumrad NN, Rabin D, Diamond MP, Lacy WW (1981) Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man. Metabolism 30:936-940
15. Saito M, Okamatsu-Ogura Y, Matsushita M et al (2009) High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58:1526-1531
16. Cypess AM, Chen YC, Sze C et al (2012) Cold but not sympathomimetics activates human brown adipose tissue in vivo. Proc Natl Acad Sci U S A 109:10001-10005
17. Vosselman MJ, van der Lans AA, Brans B et al (2012) Systemic β-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans. Diabetes 61:3106-3113
18. Carey AL, Formosa MF, van Every B et al (2013) Ephedrine activates brown adipose tissue in lean but not obese humans. Diabetologia 56:147-155
19. Ouellet V, Routhier-Labadie A, Bellemare W et al (2011) Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans. J Clin Endocrinol Metab 96:192-199
20. Miao Q, Zhao XL, Zhang QY et al (2012) Stability in brain glucose metabolism following brown adipose tissue inactivation in Chinese adults. AJNR Am J Neuroradiol 33:1464-1469
21. Karter AJ, Schillinger D, Adams AS et al (2013) Elevated rates of diabetes in Pacific Islanders and Asian subgroups: the Diabetes Study of Northern California (DISTANCE). Diabetes Care 36:574-579
22. Mangalmurti SS, Paley A, Gany F, Fisher EA, Hochman JS (2010) South Asians and risk of cardiovascular disease: current insights and trends. Ethn Dis 20:474-478
23. Flegal KM, Shepherd JA, Looker AC et al (2009) Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults. Am J Clin Nutr 89:500-508
24. Vijgen GH, Bouvy ND, Teule GJ, Brans B, Schrauwen P, van Marken Lichtenbelt WD (2011) Brown adipose tissue in morbidly obese subjects. PLoS One 6:e17247