Absolute retinal blood flow measurement with a dual-beam Doppler optical coherence tomography

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 13, 2013, Pages 7998-8003

  Dai, Cuixia ^a,b   Liu, Xiaojing ^a   Zhang, Hao F ^c   Puliafito, Carmen A ^d   Jiao, Shuliang ^a  

^a The Department of Electrical and Computer Engineering   (United States)

^b SHANGHAI INSTITUTE OF TECHNOLOGY   (China)

^c Northwestern University   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Absolute retinal blood velocity; Doppler angle; Optical coherence tomography; Retinal volumetric flow rate

Indexed keywords

ADULT; ARTICLE; BLOOD FLOW VELOCITY; FEMALE; HUMAN; HUMAN EXPERIMENT; LASER DOPPLER FLOWMETRY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RETINA BLOOD FLOW; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; VALIDATION PROCESS;

ABSOLUTE RETINAL BLOOD VELOCITY; DOPPLER ANGLE; OPTICAL COHERENCE TOMOGRAPHY; RETINAL VOLUMETRIC FLOW RATE;

ADULT; FEMALE; FOURIER ANALYSIS; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; MIDDLE AGED; REFERENCE VALUES; REGIONAL BLOOD FLOW; RETINAL VESSELS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84890018508     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12318     Document Type: Article

References (19)

1. Flammera J, Org̈ul S, Costa VP, et al. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res. 2002;21:359-393.
2. Hwang JC, Konduru R, Zhang X, et al. Relationship among visual field, blood flow, and neural structure measurements in glaucoma. Invest Ophthalmol Vis Sci. 2012;53:3020-3026.
3. Yang V, Gordon ML, Seng-Yue E, et al. High speed, wide velocity dynamic range Doppler optical coherence tomography (part II): imaging in vivo cardiac dynamics of Xenopus laevis. Opt Express. 2003;11:1650-1658.
4. White B, Pierce M, Nassif N, Cense B, et al. In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography. Opt Express. 2003;11:3490-3497.
5. Leitgeb RA, Schmetterer L, Hitzenberger CK, et al. Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography. Opt Lett. 2004;29:171-173.
6. Piao D, Zhu Q. Quantifying Doppler angle and mapping flow velocity by a combination of Doppler-shift and Dopplerbandwidth measurements in optical Doppler tomography. Appl Optics. 2003;42:5158-5166.
7. Werkmeister RM, Dragostinoff N, Pircher M, et al. Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human retinal vessels. Opt Lett. 2008;33:2967-2969.
8. Werkmeister RM, Palkovits S, Told R, et al. Response of retinal blood flow to systemic hyperoxia as measured with dual-beam bidirectional Doppler Fourier-domain optical coherence tomography. PLoS One. 2012;7:e45876-1-e45876-11.
9. Werkmeister RM, Dragostinoff N, Palkovits S, et al. Measurement of absolute blood flow velocity and blood flow in the human retina by dual-beam bidirectional Doppler Fourierdomain optical coherence tomography. Invest Ophthalmol Vis Sci. 2012;53:6062-6071.
10. Iftimia NV, Hammer DX, Ferguson RD, Mujat M, Vu D, Ferrante AA. Dual-beam Fourier domain optical Doppler tomography of zebrafish. Opt Express. 2008;16:13624-13636.
11. Pedersen CJ, Huang D, Shure MA, Rollins AM. Measurement of absolute flow velocity vector using dual-angle, delay-encoded Doppler optical coherence tomography. Opt Lett. 2007;32: 506-508.
12. Wehbe H, Ruggeri M, Jiao S, Gregori G, Puliafito CA, Zhao W. Automatic retinal blood flow calculation using spectral domain optical coherence tomography. Opt Express. 2007; 15:15193-15206.
13. Wang YM, Bower BA, Izatt JA, Tan O, Huang D. In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography. J Biomed Opt. 2007;12: 0412151-1-0412151-8.
14. Makita S, Fabritius T, Yasuno Y. Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography. Opt Lett. 2008;33:836-838.
15. Wang Y, Bower BA, Izatt JA, Tan O, Huang D. Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence tomography. J Biomed Opt. 2008;13: 064003-1-064003-9.
16. Riva CE, Grunwald JE, Sinclair SH, Petrig BL. Blood velocity and volumetric flow rate in human retinal vessels. Invest Ophthalmol Vis Sci. 1985;26:1124-1132.
17. Garcia J, Garcia PT, Rosen RB. Retinal blood flow in the normal human eye using the canon laser blood flowmeter. Ophthalmic Res. 2002;34:295-299.
18. Garhofer G, Werkmeister R, Dragostinoff N, Schmetterer L. Retinal blood flow in healthy young subjects. Invest Ophthalmol Vis Sci. 2012;53:698-703.
19. Baumann B, Potsaid B, Kraus MF, et al. Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT. Biomed Opt Express. 2011;2:1539-1552.