Thalassemia and the hypercoagulable state

Thrombosis Research

Volumn 132, Issue 6, 2013, Pages 637-641

  Sirachainan, Nongnuch ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Abnormal RBC surface; Endothelial activation; Hypercoagulable state; Platelet activation; Thalassemia; Thromboembolism

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 5 LEIDEN; CD63 ANTIGEN; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN; HEPARIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOCORTIN 5; NITRIC OXIDE; PADGEM PROTEIN; PHOSPHATIDYLSERINE; PHOSPHOLIPID ANTIBODY; PROSTACYCLIN; THROMBOMODULIN; THROMBOXANE A2; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR; WARFARIN;

ANEMIA; ANTICOAGULANT THERAPY; ANTIPHOSPHOLIPID SYNDROME; ARTERIAL THROMBOEMBOLISM; BETA THALASSEMIA; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL ACTIVATION; CONGESTIVE CARDIOMYOPATHY; DEEP VEIN THROMBOSIS; DIABETES MELLITUS; ENDOTHELIUM CELL; ERYTHROCYTE; ERYTHROCYTE TRANSFUSION; HEMOSTASIS; HUMAN; HYPERCOAGULABILITY; INCIDENCE; IRON OVERLOAD; LUNG EMBOLISM; MOYAMOYA DISEASE; ONSET AGE; PATHOGENESIS; PORTAL VEIN THROMBOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECURRENT DISEASE; REVIEW; SOUTHERN EUROPE; SPLENECTOMY; STEM CELL TRANSPLANTATION; SUPERFICIAL THROMBOPHLEBITIS; SYSTEMATIC REVIEW (TOPIC); THALASSEMIA; THALASSEMIA INTERMEDIA; THALASSEMIA MAJOR; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE LIFESPAN; THROMBOCYTOSIS; THROMBOEMBOLISM; THROMBOPHILIA; TRANSIENT ISCHEMIC ATTACK; VENOUS THROMBOEMBOLISM;

ABNORMAL RBC SURFACE; ENDOTHELIAL ACTIVATION; HYPERCOAGULABLE STATE; PLATELET ACTIVATION; THALASSEMIA; THROMBOEMBOLISM;

BLOOD TRANSFUSION; HEMATOLOGIC DISEASES; HUMANS; PLATELET ACTIVATION; THALASSEMIA; THROMBOEMBOLISM;

EID: 84889886728     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.09.029     Document Type: Review

References (48)

1. E. Kohne Hemoglobinopathies: clinical manifestations, diagnosis, and treatment Dtsch Arztebl Int 108 2011 532 540
2. R. Galanello, and R. Origa Beta-thalassemia Orphanet J Rare Dis 5 2010 11
3. K.M. Musallam, S. Rivella, E. Vichinsky, and E.A. Rachmilewitz Haematologica 98 2013 833 844
4. D. Rund, and E. Rachmilewitz Beta-thalassemia N Engl J Med 353 2005 1135 1146
5. T.M. Parker, L.M. Ward, D.L. Johnston, E. Ventureya, and R.J. Klaassen A case of Moyamoya syndrome and hemoglobin E/beta-thalassemia Pediatr Blood Cancer 52 2009 422 424
6. B.K. Goksel, H. Ozdogu, T. Yildirim, L. Oquzkurt, and S. Asma Beta-thalassemia intermedia associated with moyamoya syndrome J Clin Neurosci 17 2010 919 920
7. M. Sanefuji, S. Ohga, R. Kira, T. Yoshiura, H. Torisu, and T. Hara Moyamoya syndrome in a splenectomized patient with beta-thalassemia intermedia J Child Neurol 21 2006 75 77
8. A. Taher, H. Isma'eel, G. Mehio, D. Bignamini, A. Kattamis, and E.A. Rachmilewitz Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran Thromb Haemost 96 2006 488 491
9. S. Haghpanah, and M. Karimi Cerebral thrombosis in patients with beta-thalassemia: a systematic review Blood Coagul Fibrinolysis 23 2012 212 217
10. G. Leblebisatan, A. Bay, A. Sirikci, H. Kilincaslan, S. Sonmezisik, and S. Leblebisatan Silent cerebral infarct in child patients with beta thalassaemia intermedia Blood Coagul Fibrinolysis 23 2012 608 613
11. A.T. Taher, K.M. Musallam, M.D. Cappellini, and D.J. Weatherall Optimal management of beta thalassaemia intermedia Br J Haematol 152 2011 512 523
12. K.M. Musallam, and A.T. Taher Thrombosis in thalassemia: why are we so concerned? Hemoglobin 35 2011 503 510
13. V. Atichartakarn, P. Angchaisuksiri, K. Aryurachai, S. Onpun, S. Chuncharun, and A. Thakkinstian Relationship between hypercoagulable state and erythrocyte phosphatidylserine exposure in splenectomized haemoglobin E/beta-thalassaemic patients Br J Haematol 118 2002 893 898
14. V. Atichartakarn, S. Chuncharunee, P. Chandanamattha, K. Likittanasombat, and K. Aryurachai Correction of hypercoagulability and amelioration of pulmonary arterial hypertension by chronic blood transfusion in an asplenic hemoglobin E/beta-thalassemia patient Blood 103 2004 2844 2846
15. M.D. Cappellini, L. Robbiolo, B.M. Bottasso, R. Coppola, G. Fiorelli, and A.P. Mannucci Venous thromboembolism and hypercoagulability in splenectomized patients with thalassaemia intermedia Br J Haematol 111 2000 467 473
16. M.D. Cappellini, E. Grespi, E. Cassinerio, D. Bignamini, and G. Fiorelli Coagulation and splenectomy: an overview Ann N Y Acad Sci 1054 2005 317 324
17. A. Tripodi, M.D. Cappellini, V. Chantarangkul, L. Padovan, M.R. Fasulo, and A. Marcon Hypercoagulability in splenectomized thalassemic patients detected by whole-blood thromboelastometry, but not by thrombin generation in platelet-poor plasma Haematologica 94 2009 1520 1527
18. A. Eldor, F. Lellouche, A. Goldfarb, E.A. Rachmilewitz, and J. Maclouf In vivo platelet activation in beta-thalassemia major reflected by increased platelet-thromboxane urinary metabolites Blood 77 1991 1749 1753
19. D. Del Principe, A. Menichelli, S. Di Giulio, W. De Matteis, P. Cianciulli, and G. Papa PADGEM/GMP-140 expression on platelet membranes from homozygous beta thalassaemic patients Br J Haematol 84 1993 111 117
20. A. Ruf, M. Pick, V. Deutsch, H. Patscheke, A. Goldfarb, and E.A. Rachmilewitz In-vivo platelet activation correlates with red cell anionic phospholipid exposure in patients with beta-thalassaemia major Br J Haematol 98 1997 51 56
21. A. Eldor Abnormal platelet functions in beta thalassaemia Scand J Haematol 20 1978 447 452
22. M.A. Hussain, R.A. Hutton, O. Pavlidou, and A.V. Hoffbrand Platelet function in beta-thalassaemia major J Clin Pathol 32 1979 429 433
23. A. Eldor, Y. Krausz, H. Atlan, D. Snyder, A. Goldfarb, and E. Hy-Am Platelet survival in patients with beta-thalassemia Am J Hematol 32 1989 94 99
24. D. Tavazzi, L. Duca, G. Graziadei, A. Comino, G. Fiorelli, and M.D. Cappellini Membrane-bound iron contributes to oxidative damage of beta-thalassaemia intermedia erythrocytes Br J Haematol 112 2001 48 50
25. F. Mannu, P. Arese, M.D. Cappellini, G. Fiorelli, M. Cappadoro, and G. Giribaldi Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes Blood 86 1995 2014 2020
26. K.I. Elsayh, A.M. Zahran, T.B. El-Abaseri, A.O. Mohamed, and T.H. El-Metwally Hypoxia biomarkers, oxidative stress, and circulating microparticles in pediatric patients with thalassemia in upper Egypt Clin Appl Thromb Hemost 2013 [Epub ahead of print]
27. T. Hovav, A. Goldfarb, G. Artmann, S. Yedgar, and G. Barshtein Enhanced adherence of beta-thalassaemic erythrocytes to endothelial cells Br J Haematol 106 1999 178 181
28. A.T. Taher, K.M. Musallam, M. Karimi, A. El-Beshlawy, K. Belhoul, and S. Daar Splenectomy and thrombosis: the case of thalassemia intermedia J Thromb Haemost 8 2010 2152 2158
29. K. Oku, O. Amengual, and T. Atsumi Pathophysiology of thrombosis and pregnancy morbidity in the antiphospholipid syndrome Eur J Clin Invest 42 2012 1126 1135
30. S. Sharma, V. Raina, J. Chandra, S. Narayan, and S. Sharma Lupus anticoagulant and anticardiolipin antibodies in polytransfused beta thalassemia major Hematology 11 2006 287 290
31. M.D. Cappellini, I. Motta, K.M. Musallam, and A.T. Taher Redefining thalassemia as a hypercoagulable state Ann N Y Acad Sci 1202 2010 231 236
32. N.Y. Mustafa, R. Marouf, S. Al-Humood, S.M. Al-Fadhli, and O. Mojiminiyi Hypercoagulable state and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with beta-thalassemia major in Kuwait Acta Haematol 123 2010 37 42
33. B. Akkawat, and P. Rojnuckarin Protein S deficiency is common in a healthy Thai population J Med Assoc Thai 88 Suppl. 4 2005 S249 S254
34. E. Suehisa, T. Nomura, T. Kawasaki, and Y. Kanakura Frequency of natural coagulation inhibitor (antithrombin III, protein C and protein S) deficiencies in Japanese patients with spontaneous deep vein thrombosis Blood Coagul Fibrinolysis 12 2001 95 99
35. J. Ng, D. Thompson, J.P. Lumley, D.E. Saunders, and V. Ganesan Surgical revascularisation for childhood moyamoya Childs Nerv Syst 28 2012 1041 1048
36. A.T. Taher, K.M. Musallam, M. Karimi, A. El-Beshlawy, K. Belhoul, and S. Daar Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study Blood 115 2010 1886 1892
37. S. Fucharoen, P. Youngchaiyud, and P. Wasi Hypoxaemia and the effect of aspirin in thalassaemia Southeast Asian J Trop Med Public Health 12 1981 90 93
38. Thalassemia International Federation Splenectomy in beta thalassemia M.D. Cappellini, A. Cohen, A. Eleftheriou, A. Piga, J. Porter, A. Taher, Guidelines for the clinical management of thalassemia 2008 Team up Creations Ltd Nicosia, Cypus 116 118
39. S. Rivella, and E. Rachmilewitz Future alternative therapies for beta-thalassemia Expert Rev Hematol 2 2009 685
40. S. Vassilopoulou, E. Anagnostou, G. Paraskevas, and K. Spengos Etiology and treatment of ischaemic stroke in patients with beta-thalassemia major Eur J Neurol 18 2011 1426 1428
41. E.D. Thomas, C.D. Buckner, J.E. Sanders, T. Papayannopoulou, C. Borgna-Pignatti, and P. De Stefano Marrow transplantation for thalassaemia Lancet 2 1982 227 229
42. S. Hongeng, S. Pakakasama, A. Chuansumrit, N. Sirachainan, T. Sura, and A. Ungkanont Reduced intensity stem cell transplantation for treatment of class 3 Lucarelli severe thalassemia patients Am J Hematol 82 2007 1095 1098
43. N. Ali, S.N. Adil, M.U. Shaikh, M. Moosajee, and N. Masood Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 Exp Hematol Oncol 1 2012 13
44. G. Lucarelli, M. Andreani, and E. Angelucci The cure of the thalassemia with bone marrow transplantation Bone Marrow Transplant 28 Suppl. 1 2001 S11 S13
45. M. Sabloff, M. Chandy, Z. Wang, B.R. Logan, A. Ghavamzadeh, and C.K. Li HLA-matched sibling bone marrow transplantation for beta-thalassemia major Blood 117 2011 1745 1750
46. G. La Nasa, G. Caocci, F. Argiolu, C. Giardini, F. Locatelli, and A. Vacca Unrelated donor stem cell transplantation in adult patients with thalassemia Bone Marrow Transplant 36 2005 971 975
47. T.H. Jaing, I.J. Hung, C.P. Yang, S.H. Chen, H.T. Chung, and P.K. Tsay Unrelated cord blood transplantation for thalassaemia: a single-institution experience of 35 patients Bone Marrow Transplant 47 2012 33 39
48. N. Sirachainan, J. Thongsad, S. Pakakasama, S. Hongeng, A. Chuansumrit, and P. Kadegasem Normalized coagulation markers and anticoagulation proteins in children with severe beta-thalassemia disease after stem cell transplantation Thromb Res 129 2012 765 770