Minocycline improves postoperative cognitive impairment in aged mice by inhibiting astrocytic activation

NeuroReport

Volumn 25, Issue 1, 2014, Pages 1-6

  Jin, Wen Jie ^a   Feng, Shan Wu ^b   Feng, Zhou ^a   Lu, Shun Mei ^a   Qi, Tao ^a   Qian, Yan Ning ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

astrocytes; minocycline; postoperative cognitive dysfunction

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1; MESSENGER RNA; MINOCYCLINE; NEUROPROTECTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; LIVER RESECTION; MALE; MAZE TEST; MOUSE; NEUROPROTECTION; NONHUMAN; PARTIAL HEPATECTOMY; POSTOPERATIVE CARE; POSTOPERATIVE COGNITIVE DYSFUNCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SHAM PROCEDURE; SPATIAL MEMORY; UPREGULATION; WESTERN BLOTTING;

AGING; ANIMALS; ASTROCYTES; COGNITION; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPATECTOMY; HIPPOCAMPUS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MAZE LEARNING; MICE; MINOCYCLINE; NEUROPROTECTIVE AGENTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84889885685     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000082     Document Type: Article

References (25)

1. Papadopoulos G, Karanikolas M, Liarmakopoulou A, Papathanakos G, Korre M, Beris A. Cerebral oximetry and cognitive dysfunction in elderly patients undergoing surgery for hip fractures: A prospective observational study. Open Orthop J 2012; 6:400-405
2. Steinmetz J, Christensen KB, Lund T, Lohse N, Rasmussen LS. ISPOCD Group. Long-term consequences of postoperative cognitive dysfunction. Anesthesiology 2009; 110:548-555
3. Pereira A Jr, Furlan FA. Astrocytes and human cognition: Modeling information integration and modulation of neuronal activity. Prog Neurobiol 2010; 92:405-420
4. Zhang GL, Deng JP, Wang BH, Zhao ZW, Li J, Gao L, et al. Gypenosides improve cognitive impairment induced by chronic cerebral hypoperfusion in rats by suppressing oxidative stress and astrocytic activation. Behav Pharmacol 2011; 22:633-644
5. Hunter CL, Quintero EM, Gilstrap L, Bhat NR, Granholm AC. Minocycline protects basal forebrain cholinergic neurons from mu p75-saporin immunotoxic lesioning. Eur J Neurosci 2004; 19:3305-3316
6. Choi Y, Kim HS, Shin KY, Kim EM, Kim M, Kim HS, et al. Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models. Neuropsychopharmacology 2007; 32:2393-2404
7. Fan L, Wang TL, Xu YC, Ma YH, Ye WG. Minocycline may be useful to prevent/treat postoperative cognitive decline in elderly patients. Med Hypotheses 2011; 76:733-736
8. Hewlett KA, Corbett D. Delayed minocycline treatment reduces long-term functional deficits and histological injury in a rodent model of focal ischemia. Neuroscience 2006; 141:27-33
9. Higgins GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931; 12:186-202
10. Zhao L, Wang F, Gui B, Hua F, Qian Y. Prophylactic lithium alleviates postoperative cognition impairment by phosphorylating hippocampal glycogen synthase kinase-3b (Ser9) in aged rats. Exp Gerontol 2011; 46:1031-1036
11. Kim JS, Kim J, Kim Y, Yang M, Jang H, Kang S, et al. Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development. J Vet Sci 2011; 12:1-6
12. Gordan ML, Jungwirth B, Ohl F, Kellermann K, Kochs EF, Blobner M. Evaluation of neurobehavioral deficits following different severities of cerebral ischemia in rats: A comparison between the modified hole board test and the Morris water maze test. Behav Brain Res 2012; 235:7-20
13. Cao XZ, Ma H, Wang JK, Liu F, Wu BY, Tian AY, et al. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34:1426-1432
14. Cai ZY, Yan Y, Chen R. Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model. Neurosci Bull 2010; 26:28-36
15. Halassa MM, Fellin T, Takano H, Dong JH, Haydon PG. Synaptic islands defined by the territory of a single astrocyte. J Neurosci 2007; 27: 6473-6477
16. Parachikova A, Vasilevko V, Cribbs DH, LaFerla FM, Green KN. Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation. J Alzheimers Dis 2010; 21:527-542
17. Siopi E, Llufriu-Dabén G, Fanucchi F, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. Evaluation of late cognitive impairment and anxiety states following traumatic brain injury in mice: The effect of minocycline. Neurosci Lett 2012; 511:110-115
18. Levkovitz Y, Mendlovich S, Riwkes S, Braw Y, Levkovitch-Verbin H, Gal G, et al. A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia. J Clin Psychiatry 2010; 71:138-149
19. Cai ZY, Yan Y, Sun SQ, Zhang J, Huang LG, Yan N, et al. Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusion. Neurosci Bull 2008; 24:305-313
20. Fujita Y, Ishima T, Kunitachi S, Hagiwara H, Zhang L, Iyo M, et al. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline. Prog Neuropsychopharmacol Biol Psychiatry 2008; 32:336-339
21. Rosczyk HA, Sparkman NL, Johnson RW. Neuroinflammation and cognitive function in aged mice following minor surgery. Exp Gerontol 2008; 43:840-846
22. Sauër AM, Kalkman C, van Dijk D. Postoperative cognitive decline. J Anesth 2009; 23:256-259
23. Cibelli M, Fidalgo AR, Terrando N, Ma D, Monaco C, Feldmann M, et al. Role of interleukin-1beta in postoperative cognitive dysfunction. Ann Neurol 2010; 68:360-368
24. Wan Y, Xu J, Ma D, Zeng Y, Cibelli M, Maze M. Postoperative impairment of cognitive function in rats: A possible role for cytokine-mediated inflammation in the hippocampus. Anesthesiology 2007; 106:436-443
25. Pickering M, O'Connor JJ. Pro-inflammatory cytokines and their effects in the dentate gyrus. Prog Brain Res 2007; 163:339-354