The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Ferguson, Brent W ^a   Gao, Xinsheng ^a   Zelazowski, Maciej J ^a   Lee, Jaeho ^a   Jeter, Collene R ^a   Abba, Martin C ^b   Aldaz, C M ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

ANGPTL4; Breast Cancer; SMAD3; TGF ; WWOX

Indexed keywords

CELL PROTEIN; DNA; GLUTATHIONE TRANSFERASE; PROTEIN ANGPTL4; PROTEIN FST; PROTEIN PTHLH; PROTEIN SERPINE1; SHORT HAIRPIN RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR PROTEIN; UNCLASSIFIED DRUG; WW DOMAIN CONTAINING OXIDOREDUCTASE;

ARTICLE; BASAL LIKE BREAST CANCER; BIOINFORMATICS; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CELL; CANCER GROWTH; CELL ADHESION; CELL CYCLE; CELL MOTILITY; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN MCF 7; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; COMPUTER ANALYSIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG METASTASIS; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; PHENOTYPE; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; TRIPLE NEGATIVE BREAST CANCER; TUMOR GENE; UPREGULATION; WW DOMAIN CONTAINING OXIDOREDUCTASE GENE;

ANGIOPOIETINS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HUMANS; MCF-7 CELLS; OXIDOREDUCTASES; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TRANSPORT; SMAD3 PROTEIN; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 84889872051     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-593     Document Type: Article

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