Offspring psychopathology following preconception, prenatal and postnatal maternal bereavement stress

Psychological Medicine

Volumn 44, Issue 1, 2014, Pages 71-84

  Class, Q A ^a   Abel, K M ^b   Khashan, A S ^c   Rickert, M E ^a   Dalman, C ^d   Larsson, H ^d   Hultman, C M ^d   Langstrom N ^d   Lichtenstein, P ^d   D'Onofrio, B M ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Attention deficit hyperactivity disorder; autism; postnatal; preconception; prenatal; psychiatric; psychopathology; schizophrenia; stress; suicide

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BEREAVEMENT; BIPOLAR DISORDER; CHILD; ENVIRONMENTAL EXPOSURE; FACTUAL DATABASE; FEMALE; HUMAN; MALE; MENTAL DISEASE; MENTAL STRESS; MOTHER; PREGNANCY; PREGNANCY COMPLICATION; PRENATAL EXPOSURE; PROPORTIONAL HAZARDS MODEL; PSYCHOLOGICAL ASPECT; PUERPERIUM; RISK FACTOR; SCHIZOPHRENIA; STATISTICS; SUICIDE; SUICIDE ATTEMPT; SWEDEN; YOUNG ADULT;

ADOLESCENT; ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEREAVEMENT; BIPOLAR DISORDER; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DATABASES, FACTUAL; FEMALE; HUMANS; MALE; MATERNAL EXPOSURE; MENTAL DISORDERS; MOTHERS; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SCHIZOPHRENIA; STRESS, PSYCHOLOGICAL; SUICIDE; SUICIDE, ATTEMPTED; SWEDEN; YOUNG ADULT;

EID: 84889765294     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291713000780     Document Type: Article

References (90)

1. Abel KM, Wicks S, Susser ES, Dalman C, Pedersen MG, Mortensen PB, Webb RT (2010). Birth weight, schizophrenia, and adult mental disorder. Archives of General Psychiatry 67, 923-930.
2. Academy of Medical Sciences Working Group (2007). Identifying the environmental causes of disease: how should we decide what to believe and when to take action Academy of Medical Sciences: London.
3. Arbuckle NW, de Vries B (1995). The long-term effects of later life spousal and parental bereavement on personal functioning. The Gerontologist 35, 637-647.
4. Bagner DM, Pettit JW, Lewinsohn PM, Seeley JR (2010). Effect of maternal depression on child behavior: A sensitive period Journal of the American Academy of Child and Adolescent Psychiatry 49, 699-707.
5. Bailey A, Luthert P, Dean A, Harding B, Janota I, Montgomery M, Rutter M, Lantos P (1998). A clinicopathological study of autism. Brain 121, 889-905. (Pubitemid 28220896)
6. Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES, Nestler EJ (2010). Early life programming and neurodevelopmental disorders. Biological Psychiatry 68, 314-319.
7. Barker DJP (1998). Mothers, Babies and Health in Later Life. Churchill Livingstone: Edinburgh.
8. Bauman ML, Kemper TL (1994). Neuroanatomic observations of the brain in autism. In The Neurobiology of Autism (ed. M. L. Bauman and T. L. Kemper), pp. 119-145. John Hopkins University Press: Baltimore.
9. Bauman ML, Kemper TL (2005). Neuroanatomic observations of the brain in autism: A review and future directions. International Journal of Developmental Neuroscience 23, 183-187. (Pubitemid 40313551)
10. Beversdorf DQ, Manning SE, Hillier A, Anderson SL, Nordgren RE, Walters SE, Nagaraja HN, Cooley WC, Gaelic SE, Bauman ML (2005). Timing of prenatal stressors and autism. Journal of Autism and Developmental Disorders 35, 471-478. (Pubitemid 41216433)
11. Beydoun H, Saftlas AF (2008). Physical and mental health outcomes of prenatal maternal stress in human and animal studies: A review of recent evidence. Paediatric and Perinatal Epidemiology 22, 438-466.
12. Brand SR, Engel SM, Canfield RL, Yehuda R (2006). The effect of maternal PTSD following in utero trauma exposure on behavior and temperament in the 9-month-old infant. Annals of the New York Academy of Sciences 1071, 454-458. (Pubitemid 44126755)
13. Brent DA, Mann JJ (2005). Family genetic studies, suicide, and suicidal behavior. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics 133C, 13-24. (Pubitemid 40194125)
14. Brent DA, Mann JJ (2006). Familial pathways to suicidal behavior: understanding and preventing suicide among adolescents. New England Journal of Medicine 355, 2719-2721. (Pubitemid 46021507)
15. Brown AS, Susser ES, Lin SP, Neugebauer R, Gorman JM (1995). Increased risk of affective disorder in males after second trimester prenatal exposure to the Dutch hunger winter of 1944-1945. British Journal of Psychiatry 166, 601-606.
16. Brown AS, van Os J, Driessens C, Hoek HW, Susser ES (2000). Further evidence of relation between prenatal famine and major affective disorder. American Journal of Psychiatry 157, 190-195. (Pubitemid 30080897)
17. Buss C, Davis EP, Muftuler LT, Head K, Sandman CA (2010). High pregnancy anxiety during mid-gestation is associated with decreased gray matter density in 6-9-year-old children. Psychoneuroendocrinology 35, 141-153.
18. Buss C, Davis EP, Shahbaba B, Pruessner JC, Head K, Sandman CA (2012). Maternal cortisol over the course of pregnancy and subsequent child amygdala and hippocampus volumes and affective problems. Proceedings of the National Academy of Sciences USA 109, E1312-E1319.
19. Caspi A, Moffitt TE, Newman DL, Silva PA (1996). Behavioural observations at age 3 years predicts psychiatric disorders: longitudinal evidence from a birth cohort. Archives of General Psychiatry 53, 1033-1039. (Pubitemid 26384672)
20. Centre for Epidemiology (2003). The Swedish Medical Birth Register-a summary of content and quality. (http://www. socialstyrelsen.se/Lists/ Artikelkatalog/Attachments/10655/2003-112-3-20031123.pdf).
21. Charil A, Laplante DP, Vaillancourt C, King S (2010). Prenatal stress and brain development. Brain Research Reviews 65, 56-79.
22. Class QA, Lichtenstein P, Langstrom N, D'Onofrio BM (2011). Timing of prenatal maternal severe life events and adverse pregnancy outcomes: A population study of 2.6 million pregnancies. Psychosomatic Medicine 73, 234-241.
23. Cnattingius S, Ericson A, Gunnarskog J, Kallen B (1990). A quality study of a medical birth registry. Scandinavian Journal of Social Medicine 18, 105-109.
24. Dunkel-Schetter C, Glynn L (2011). Stress in pregnancy: empirical evidence and theoretical issues to guide interdisciplinary research. In Handbook of Stress (ed. R. Contrada and A. Baum), pp. 321-343. New York, NY: Springer Publishing Company.
25. Epstein T, Saltzman-Benaiah J, O'Hare A, Goll JC, Tuck S (2008). Associated features of Asperger Syndrome and their relationship to parenting stress. Child: Care, Health and Development 34, 503-511. (Pubitemid 351818805)
26. Fazel S, Grann M (2006). The population impact of severe mental illness on violent crime. American Journal of Psychiatry 163, 1397-1403. (Pubitemid 44464411)
27. Ganz ML (2007). The lifetime distribution of the incremental societal costs of autism. Archives of Pediatric Adolescent Medicine 161, 343-349. (Pubitemid 46556364)
28. Gluckman PD, Hanson MA (2004). Living with the past: evolution, development, and patterns of disease. Science 305, 1733-1736. (Pubitemid 39249632)
29. Glynn L, Wadhwa PD, Schetter CD, Chicz-Demet A, Sandman CA (2001). When stress happens matters: effects of earthquake timing on stress responsivity in pregnancy. American Journal of Obstetrics and Gynecology 184, 637-642. (Pubitemid 32236713)
30. Goodman SH, Gotlib IH (1999). Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychological Review 106, 458-490.
31. Guinchat V, Thorsen P, Laurent C, Cans C, Bodeau N, Cohen D (2012). Pre-, peri-and neonatal risk factors for autism. Acta Obstetrica Gynecologica Scandinavica 91, 287-300.
32. Heim C, Newport DJ, Mletzko T, Miller AH, Nemeroff CB (2008). The link between childhood truama and depression: insights from HPA axis studies in humans. Psychoneuroendocrinology 33, 693-710.
33. Hultman CM, Torrang A, Tuvblad C, Cnattingius S, Larsson J, Lichtenstein P (2007). Birth weight and attention-deficit/hyperactivity symptoms in childhood and early adolescence: A prospective Swedish twin study. Journal of the American Academy of Child and Adolescent Psychiatry 46, 370-377.
34. Huttunen M, Niskanen P (1978). Prenatal loss of father and psychiatric disorders. Archives of General Psychiatry 35, 429-431. (Pubitemid 8337034)
35. Jablensky A (2000). Epidemiology of schizophrenia: The global burden of disease and disability. European Archives of Psychiatry and Clinical Neuroscience 250, 274-285. (Pubitemid 32002381)
36. Jirtle RL, Skinner MK (2007). Environmental epigenomics and disease susceptibility. Nature Reviews Genetics 8, 253-262. (Pubitemid 46439287)
37. Khashan AS, Abel KM, McNamee R, Pedersen MG, Webb RT, Baker PN, Kenny LC, Mortensen PB (2008a). Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Archives of General Psychiatry 65, 146-152. (Pubitemid 351214313)
38. Khashan AS, McNamee R, Abel KM, Mortensen PB, Kenny LC, Pedersen MG, Webb RT, Baker PN (2009). Rates of preterm birth following antenatal maternal exposure to severe life events: A population-based cohort study. Human Reproduction 24, 429-437.
39. Khashan AS, McNamee R, Abel KM, Pedersen MG, Webb RT, Kenny LC, Mortensen PB, Baker PN (2008b). Reduced infant birthweight consequent upon maternal exposure to severe life events. Psychosomatic Medicine 70, 688-694.
40. Khashan AS, McNamee R, Henriksen TB, Pedersen MG, Kenny LC, Abel KM, Mortensen PB (2011). Risk of affective disorders following prenatal exposure to severe life events: A Danish population-based cohort study. Journal of Psychiatric Research 45, 879-885.
41. King S, Laplante DP (2005). The effects of prenatal maternal stress on children's cognitive development: Project Ice Storm. Stress 8, 35-45. (Pubitemid 40776471)
42. Kinney DK, Miller AM, Crowley DJ, Huang E, Gerber E (2008a). Autism prevalence following prenatal exposure to hurricanes and tropical storms in Louisiana. Journal of Autism and Developmental Disorders 38, 481-488. (Pubitemid 351322368)
43. Kinney DK, Munir K, Crowley DJ, Miller AM (2008b). Prenatal stress and risk for autism. Neuroscience and Biobehavioral Reviews 32, 1519-1532.
44. Landau R, Avital M, Berger A, Atzaba-Poria N, Arbelle S, Faroy M, Auerbach JG (2010). Parenting of 7-month-old infants at familial risk for attention deficit/hyperactivity disorder. Infant Mental Health Journal 31, 141-158.
45. Li J, Olsen J, Vestergaard M, Obel C (2010). Attention-deficit/ hyperactivity disorder in the offspring following prenatal maternal bereavement: A nationwide follow-up study in Denmark. European Child and Adolescent Psychiatry 19, 747-753.
46. Li J, Vestergaard M, Obel C, Christensen J, Precht DH, Lu M, Olsen J (2009). A nationwide study on the risk of autism after prenatal stress exposure to maternal bereavement. Pediatrics 123, 1102-1107.
47. Lichtenstein P, Yip BH, Bjork C, Pawitan Y, Cannon T, Sullivan PF, Hultman CM (2009). Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study. Lancet 373, 234-239.
48. Lindstrom K, Lindblad F, Hjern A (2009). Psychiatric morbidity in adolescents and young adults born preterm: A Swedish national cohort study. Pediatrics 123, e47-e53.
49. Lindstrom K, Lindblad F, Hjern A (2011). Preterm birth and attention-deficit/hyperactivity disorder in schoolchildren. Pediatrics 127, 858-865.
50. Liu J, Dietz K, Deloyht JM, Pedre X, Kelkar D, Kaur J, Vialou V, Lobo MK, Dietz DM, Nestler EJ, Dupree J, Casaccia P (2012). Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nature Neuroscience 15, 1621-1623.
51. Losh M, Esserman D, Anckarsater H, Sullivan PF, Lichtenstein P (2011). Lower birth weight indicates higher risk of autistic traits in discordant twin pairs. Psychological Medicine 42, 1091-1102.
52. Mann JJ (2003). Neurobiology of suicidal behavior. Nature Reviews Neuroscience 4, 819-828.
53. Mantymaa M, Puura K, Luoma I, Latva R, Salmelin RK, Tamminen T (2012). Predicting internalizing and externalizing problems at five years by child and parental factors in infancy and toddlerhood. Child Psychiatry and Human Development 43, 153-170.
54. Matthews KA, Rodin J (1992). Pregnancy alters blood pressure responses to psychological and physical challenge. Psychophysiology 29, 232-240.
55. Meaney MJ (2010). Epigenetics and the biological definition of gene×environment interactions. Child Development 81, 41-79.
56. Mittendorfer-Rutz E, Rasmussen F, Wasserman D (2004). Restricted fetal growth and adverse maternal psychosocial and socioeconomic conditions as risk factors for suicidal behavior of offspring: A cohort study. Lancet 364, 1135-1140. (Pubitemid 39296600)
57. Monk C, Georgieff MK, Osterholm EA (2013). Research review: maternal prenatal distress and poor nutrition-mutually influencing risk factors affecting infant neurocognitive development. Journal of Child Psychology and Psychiatry, and Allied Disciplines 54, 115-130.
58. Mortensen PB, Pedersen CB, Melbye M, Mors O, Ewald H (2003). Individual and familial risk factors for bipolar affective disorders in Denmark. Archives of General Psychiatry 60, 1209-1215. (Pubitemid 37494074)
59. Moster D, Lie RT, Markestad T (2008). Long-term medical and social consequences of preterm birth. New England Journal of Medicine 359, 262-273. (Pubitemid 352008441)
60. O'Connor TG, Heron J, Golding J, Glover V; ALSPAC Study Team (2003). Maternal antenatal anxiety and behavioural/emotional problems in children: A test of a programming hypothesis. Journal of Child Psychology and Psychiatry 44, 1025-1036. (Pubitemid 37254145)
61. Pelham WE, Foster EM, Robb JA (2007). The economic impact of attention-deficit/hyperactivity disorder in children and adolescents. Journal of Pediatric Psychology 32, 711-727. (Pubitemid 47356048)
62. Piven J, Palmer P (1999). Psychiatric disorder and the broad autism phenotype: evidence from a family study of multiple-incidence autism families. American Journal of Psychiatry 156, 557-563. (Pubitemid 29162976)
63. Polanczyk G, De Lima MS, Horta BL, Biederman J, Rohde LA (2007). The worldwide prevalence of ADHD: A systematic review and metaregression analysis. American Journal of Psychiatry 164, 942-948. (Pubitemid 46972911)
64. Rai D, Golding J, Magnusson C, Steer C, Lewis G, Dalman C (2012). Prenatal and early life exposure to stressful life events and risk of autism spectrum disorders: population-based studies in Sweden and England. PLoS One 7, e38893.
65. Rice F, Harold GT, Boivin J, van den Bree M, Hay DF, Thapar A (2010). The links between prenatal stress and offspring development and psychopathology: disentangling environmental and inherited influences. Psychological Medicine 40, 335-345.
66. Rodriguez A, Bohlin G (2005). Are maternal smoking and stress during pregnancy related to ADHD symptoms in children Journal of Child Psychology and Psychiatry 46, 246-254. (Pubitemid 40439430)
67. Ronald A, Pennell CE, Whitehouse AJO (2011). Prenatal maternal stress associated with ADHD and autistic traits in early childhood. Frontiers in Developmental Psychology 1, 223.
68. Rosenberg SD, Weili L, Mueser KT, Jankowski MK, Cournos F (2007). Correlates of adverse childhood events among adults with schizophrenia spectrum disorders. Psychiatric Services 58, 245-253. (Pubitemid 46340470)
69. Rutter M (2007). Proceeding from observed correlation to causal inference: The use of natural experiments. Perspectives on Psychological Science 2, 377-395.
70. Rutter M, Kim-Cohen J, Maughan B (2006). Continuities and discontinuities in psychopathology between childhood and adulthood. Journal of Child Psychology and Psychiatry 47, 276-295. (Pubitemid 43356060)
71. Schelar E, Franzetta K, Manlove J (2007). Repeat Teen Childbearing: Differences Across States and by Race and Ethnicity. Research Brief. Child Trends: Washington, DC.
72. Schulz R, Mendelsohn AB, Haley WE, Mahoney D, Allen RS, Zhang S, Thompson L, Belle SH, Resources for Enhancing Alzheimer's Caregiver Health Investigators (2003). End-of-life care and the effects of bereavement on family caregivers of persons with dementia. New England Journal of Medicine 349, 1936-1942. (Pubitemid 37409711)
73. Selten JP, Cantor-Graae E, Nahon D, Levav I, Aleman A, Kahn RS (2003). No relationship between risk of schiophrenia and prenatal exposure to stress during the Six-Day War or Yom Kippur War in Israel. Schizophrenia Research 63, 131-135. (Pubitemid 36929855)
74. Shachar-Dadon A, Schulkin J, Leshem M (2009). Adversity before conception will affect adult progeny in rats. Developmental Psychology 45, 9-16.
75. Simonoff E, Pickles A, Charman T, Chandler S, Loucas T, Baird G (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry 47, 921-929.
76. Smith GCS, Pell JP, Dobbie R (2003). Interpregnancy interval and risk of preterm birth and neonatal death: retrospective cohort study. British Medical Journal 327, 313.
77. Smith GD (2008). Assessing intrauterine influences on offspring health outcomes: can epidemiological studies yield robust findings Basic and Clinical Pharmacology and Toxicology 102, 245-256. (Pubitemid 351143439)
78. Smits L, Essed GGM (2001). Short interpregnancy intervals and unfavourable pregnancy outcome: role of folate depletion. Lancet 358, 2074-2077. (Pubitemid 34084837)
79. St Clair D, Xu M, Wang P, Yu Y, Fang Y, Zhang F, Zheng X, Gu N, Feng G, Sham P, He L (2005). Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. Journal of the American Medical Association 294, 557-562. (Pubitemid 41126897)
80. Statistics Sweden (2006). Multi-Generation Register 2005. A Description of Contents and Quality. Statistics Sweden: Orebro.
81. Statistics Sweden (2011). Educational Attainment of the Population (http://www.scb.se/Pages/SubjectArea-3930.aspx). Accessed 1 November 2011.
82. Talge NM, Neal C, Glover V (2007). Antenatal maternal stress and long-term effects on child neurodevelopment: how and why Journal of Child Psychology and Psychiatry 48, 245-261. (Pubitemid 46372120)
83. Tidemalm D, Langstrom N, Lichtenstein P, Runeson B (2008). Risk of suicide after suicide attempt according to coexisting psychiatric disorder: Swedish cohort study with long term follow-up. British Medical Journal 337, a2205.
84. Van den Bergh BR, Mulder EJ, Mennes M, Glover V (2005). Antenatal maternal anxiety and stress and the neurobehavioural development of the fetus and child: links and possible mechanisms. A review. Neuroscience and Biobehavioral Reviews 29, 237-258. (Pubitemid 40461742)
85. Van den Bergh BR, Van Calster BV, Smits T, Van Huffel S, Lagae L (2008). Antenatal maternal anxiety is related to HPA axis dysregulation and self-reported depressive symptoms in adolescence: A prospective study on the fetal origins of depressed mood. Neuropsychopharmacology 33, 536-545.
86. van Os J, Selten JP (1998). Prenatal exposure to maternal stress and subsequent schizophrenia. The May 1940 invasion of the Netherlands. British Journal of Psychiatry 172, 324-326. (Pubitemid 28183858)
87. Wadhwa PD (2005). Psychoneuroendocrine processes in human pregnancy influence fetal development and health. Psychoneuroendocrinology 30, 724-743. (Pubitemid 40775740)
88. Ward AJ (1990). A comparison and analysis of the presence of family problems during pregnancy of mothers of 'autistic' children and mothers of typically developing children. Child Psychiatry and Human Development 20, 279-288. (Pubitemid 20342917)
89. Whiffen VE, Gotlib IH (1989). Infants of postpartum depressed mothers: temperament and cognitive status. Journal of Abnormal Psychology 98, 274-279. (Pubitemid 19213242)
90. Williams JMG, Pollock LR (2000). The psychology of suicidal behavior. In International Handbook of Suicide and Attempted Suicide (ed. K. Hawton and K. V. Heeringen), pp. 79-93. Wiley: Chichester.