Lower birth weight indicates higher risk of autistic traits in discordant twin pairs

Psychological Medicine

Volumn 42, Issue 5, 2012, Pages 1091-1102

  Losh, M ^a   Esserman, D ^b,c   Anckarsater H ^d,e   Sullivan, P F ^b   Lichtenstein, P ^f  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c The University of North Carolina at Chapel Hill   (United States)

^d LUND UNIVERSITY   (Sweden)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

^f KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Autism; birth weight; twin

Indexed keywords

ARTICLE; AUTISM; CHILD; COHORT ANALYSIS; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; LOW BIRTH WEIGHT; MALE; NEWBORN; PSYCHOLOGIC TEST; PSYCHOLOGICAL ASPECT; REGISTER; RISK; RISK FACTOR; SWEDEN; TWINS;

CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; COHORT STUDIES; DISEASES IN TWINS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INTERVIEW, PSYCHOLOGICAL; MALE; ODDS RATIO; REGISTRIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SWEDEN; TWINS;

EID: 84859253942     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291711002339     Document Type: Article

References (66)

1. Anckarsäter H, Larson T, Hansson SL, Carlström E, Ståhlberg O, Gillberg C, Råstam R, Gillberg C, Lichtenstein P (2008). Child neurodevelopmental and behavioral problems are intercorrelated and dimensionally 1distributed in the general population. The Open Psychiatry Journal 2, 5-11.
2. Anckarsäter H, Lichtenstein P, Carlstedt E, Ståhlberg O, Gillberg C (2007). Psychometric development of The Autism - Tics, AD/HD and other Comorbidities (A-TAC) inventory. Full version with gate structure ; based on clinic and general population data (www.childnps.se).
3. Bailey A, Le Couteur A, Gottesman I, Bolton P, Simonoff E, Yuzda E, Rutter M (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine 25, 63-77.
4. Ben Itzchak E, Lahat E, Zachor DA (2011). Advanced parental ages and low birth weight in autism spectrum disorders - rates and effect on functioning. Research in Developmental Disabilities 32, 1776-1781.
5. Beversdorf DQ, Manning SE, Hillier A, Anderson SL, Nordgren RE, Walters SE, Nagaraja HN, Cooley WC, Gaelic SE, Bauman ML (2005). Timing of prenatal stressors and autism. Journal of Autism and Developmental Disorders 35, 471-478. (Pubitemid 41216433)
6. Blickstein I (1991). The definition, diagnosis, and management of growth-discordant twins: an international census survey. Acta Geneticae Medicae et Gemellologiae 40, 345-351.
7. Blickstein I, Lancet M (1988). The growth discordant twin. Obstetrical and Gynecological Survey 43, 509-515.
8. Bolton P, Macdonald H, Pickles A, Rios P, Goode S, Crowson M, Bailey A, Rutter M (1994). A case-control family history study of autism. Journal of Child Psychology and Psychiatry 35, 877-900. (Pubitemid 24213267)
9. Bolton PF, Griffiths PD (1997). Association of tuberous sclerosis of temporal lobes with autism and atypical autism. Lancet 349, 392-395. (Pubitemid 27077668)
10. Bolton PF, Murphy M, Macdonald H, Whitlock B, Pickles A, Rutter M (1997). Obstetric complications in autism: consequences or causes of the condition? Journal of the American Academy of Child and Adolescent Psychiatry 36, 272-281. (Pubitemid 27049577)
11. Branum AM, Schoendorf KC (2003). The effect of birth weight discordance on twin neonatal mortality. Obstetrics and Gynecology 101, 570-574. (Pubitemid 36288500)
12. Bryson SE, Smith IM, Eastwood D (1988). Obstetrical suboptimality in autistic children. Journal of the American Academy of Child and Adolescent Psychiatry 27, 418-422.
13. Burd L, Severud R, Kerbeshian J, Klug MG (1999). Prenatal and perinatal risk factors for autism. Journal of Perinatal Medicine 27, 441-450. (Pubitemid 30011800)
14. Burstyn I, Sithole F, Zwaigenbaum L (2010). Autism spectrum disorders, maternal characteristics and obstetric complications among singletons born in Alberta, Canada. Chronic Diseases in Canada 30, 125-134.
15. CDC (2009). Prevalence of autism spectrum disorders -Autism and Developmental Disabilities Monitoring Network, United States, 2006. MMWR CDC Surveillance Summaries 58, 1-20.
16. Chess S (1971). Autism in children with congenital rubella. Journal of Autism and Childhood Schizophrenia 1, 33-47.
17. Chess S (1977). Follow-up report on autism in congenital rubella. Journal of Autism and Childhood Schizophrenia 7, 69-81. (Pubitemid 8081958)
18. Clausson B, Lichtenstein P, Cnattingius S (2000). Genetic influence on birthweight and gestational length determined by studies in offspring of twins. British Journal of Obstetrics and Gynaecology 107, 375-381. (Pubitemid 30145380)
19. Constantino JN, Todd RD (2003). Autistic traits in the general population: a twin study. Archives of General Psychiatry 60, 524-530. (Pubitemid 36539062)
20. Constantino JN, Zhang Y, Frazier T, Abbacchi AM, Law P (2010). Sibling recurrence and the genetic epidemiology of autism. American Journal of Psychiatry 167, 1349-1356.
21. Cryan E, Byrne M, O'Donovan A, O'Callaghan E (1996). A case-control study of obstetric complications and later autistic disorder. Journal of Autism and Developmental Disorders 26, 453-460. (Pubitemid 26269875)
22. Deb S, Prasad KB, Seth H, Eagles JM (1997). A comparison of obstetric and neonatal complications between children with autistic disorder and their siblings. Journal of Intellectual Disability Research 41, 81-86. (Pubitemid 27424965)
23. Falconer DS (1981). Introduction to Quantitative Genetics, 2nd edn. Longman: London/New York.
24. Folstein S, Rutter M (1977). Infantile autism: a genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry 18, 297-321.
25. Gielen M, Lindsey PJ, Derom C, Loos RJF, Souren NY, Paulussen ADC, Zeegers MP, Derom R, Vlietinck R, Nijhuis JG (2008). Twin-specific intrauterine 'growth' charts based on cross-sectional birthweight data. Twin Research and Human Genetics 11, 224-235. (Pubitemid 351507006)
26. Hack M, Taylor HG, Schluchter M, Andreias L, Drotar D, Klein N (2009). Behavioral outcomes of extremely low birth weight children at age 8 years. Journal of Developmental and Behavioral Pediatrics 30, 112-130.
27. Hallmayer J, Cleveland S, Torres A, Phillips J, Cohen B, Torigoe T, Miller J, Fedele A, Collins J, Smith K, Lotspeich L, Croen LA, Ozonoff S, Lajonchere C, Grether JK, Risch N (2011). Genetic heritability and shared environmental factors among twin pairs with autism. Archives of General Psychiatry. Published online: 4 July 2011. doi:10.1001/archgenpsychiatry.2011. 76.
28. Hansson SL, Rojvall AS, Rastam M, Gillberg C, Anckarsater H (2005). Psychiatric telephone interview with parents for screening of childhood autismtics, attention-deficit hyperactivity disorder and other comorbidities (A-TAC): preliminary reliability and validity. British Journal of Psychiatry 187, 262-267. (Pubitemid 41306108)
29. Hoekstra RA, Happe F, Baron-Cohen S, Ronald A (2009). Association between extreme autistic traits and intellectual disability: insights from a general population twin study. British Journal of Psychiatry 195, 531-536.
30. Hrubec Z, Robinette CD (1984). The study of human twins in medical research. New England Journal of Medicine 310, 435-441. (Pubitemid 14186360)
31. Indredavik MS, Vik T, Heyerdahl S, Kulseng S, Fayers P, Brubakk AM (2004). Psychiatric symptoms and disorders in adolescents with low birth weight. Archives of Disease in Childhood. Fetal and Neonatal Edition 89, F445-F450. (Pubitemid 39178826)
32. Juul-Dam N, Townsend J, Courchesne E (2001). Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. Pediatrics 107, E63.
33. Kolevzon A, Gross R, Reichenberg A (2007). Prenatal and perinatal risk factors for autism. Archives of Pediatrics and Adolescent Medicine 161, 326-333.
34. Kuban KC, O'Shea TM, Allred EN, Tager-Flusberg H, Goldstein DJ, Leviton A (2009). Positive screening on the Modified Checklist for Autism in Toddlers (M-CHAT) in extremely low gestational age newborns. Journal of Pediatrics 154, 535-540.
35. Larson T, Anckarsater H, Gillberg C, Stahlberg O, Carlstrom E, Kadesjo B, Rastam M, Lichtenstein P (2010). The autism - tics, AD/HD and other comorbidities inventory (A-TAC): further validation of a telephone interview for epidemiological research. BMC Psychiatry 10, 1.
36. Larsson HJ, Eaton WW, Madsen KM, Vestergaard M, Olesen AV, Agerbo E, Schendel D, Thorsen P, Mortensen PB (2005). Risk factors for autism: perinatal factors, parental psychiatric history, and socioeconomic status. American Journal of Epidemiology 161, 916-925. (Pubitemid 40656413)
37. Lauritsen MB, Pedersen CB, Mortensen PB (2005). Effects of familial risk factors and place of birth on the risk of autism: a nationwide register-based study. Journal of Child Psychology and Psychiatry 46, 963-971. (Pubitemid 44192664)
38. Levy S, Zoltak B, Saelens T (1988). A comparison of obstetrical records of autistic and nonautistic referrals for psychoeducational evaluations. Journal of Autism and Developmental Disorders 18, 573-581. (Pubitemid 19025241)
39. Lichtenstein P, Carlström C, Rastam M, Gillberg C, Anckarsater H (2010). The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. American Journal of Psychiatry 167, 1357-1363.
40. Lichtenstein P, Sullivan PF, Cnattingius S, Gatz M, Johansson S, Carlström C, Bjö rk C, Svartengren M, Wolk A, Klareskog L, De Faire U, Schalling M, Palmgren J, Pedersen NL (2006). The Swedish Twin Registry in the third millennium: an update. Twin Research and Human Genetics 9, 875-882. (Pubitemid 46093773)
41. Limperpoulos C (2009). Autism spectrum disorders insurvivors of extreme prematurity. Clinical Perinatology 36, 791-805.
42. Littell RC, Milliken GA, Stroup WW, Wolfinger RD (1996). SAS System for Mixed Models. SAS Institute, Inc.: Cary, NC.
43. Losh M, Childress D, Lam K, Piven J (2008). Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 147B, 424-433. (Pubitemid 351830798)
44. Lundstrom S, Chang Z, Kerekes N, Gumpert CH, Rastam M, Gillberg C, Lichtenstein P, Anckarsater H (2011). Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults. Psychological Medicine 41, 2423-2433.
45. Lundstrom S, Haworth CM, Carlström E, Gillberg C, Mill J, Rastam M, Hultman CM, Ronald A, Anckarsater H, Plomin R, Lichtenstein P, Reichenberg A (2010). Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies. Journal of Child Psychology and Psychiatry 51, 850-856.
46. Magnus P, Gjessing HK, Skrondal A, Skjaerven R (2001). Paternal contribution to birth weight. Journal of Epidemiology and Community Health 55, 873-877. (Pubitemid 33097220)
47. Maimburg RD, Vaeth M (2006). Perinatal risk factors and infantile autism. Acta Psychiatrica Scandinavica 114, 257-264. (Pubitemid 44379126)
48. Markowitz PI (1983). Autism in a child with congenital cytomegalovirus infection. Journal of Autism and Developmental Disorders 13, 249-253. (Pubitemid 14247222)
49. Mason-Brothers A, Ritvo ER, Pingree C, Petersen PB, Jenson WR, McMahon WM, Freeman BJ, Jorde LB, Spencer MJ, Mo A, Ritvo A (1990). The UCLA-University of Utah epidemiologic survey of autism: prenatal, perinatal, and postnatal factors. Pediatrics 86, 514-519. (Pubitemid 20337140)
50. O'Brien WF, Knuppel RA, Scerbo JC, Rattan PK (1986). Birth weight in twins: an analysis of discordancy and growth retardation. Obstetrics and Gynecology 67, 483-486. (Pubitemid 16116263)
51. Ozonoff S, Young GS, Carter A, Messinger D, Yirmiya N, Zwaigenbaum L, Bryson S, Carver LJ, Constantino JN, Dobkins K, Hutman T, Iverson JM, Landa R, Rogers SJ, Sigman M, Stone WL (2011). Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium Study. Pediatrics. Published online: 15 August 2011. doi:10.1542/peds.2010-2825.
52. Piven J, Palmer P, Landa R, Santangelo S, Jacobi D, Childress D (1997). Personality and language characteristics in parents from multiple-incidence autism families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 74, 398-411. (Pubitemid 27349377)
53. Piven J, Simon J, Chase GA, Wzorek M, Landa R, Gayle J, Folstein S (1993). The etiology of autism: pre-, peri- and neonatal factors. Journal of the American Academy of Child and Adolescent Psychiatry 32, 1256-1263. (Pubitemid 23319188)
54. Reichenberg A, Gross R, Weiser M, Bresnahan M, Silverman J, Harlap S, Rabinowitz J, Shulman C, Malaspina D, Lubin G, Knobler H, Davidson M, Susser E (2006). Advancing paternal age and autism. Archives of General Psychiatry 63, 1026-1032. (Pubitemid 44330462)
55. Ronald A, Happe F, Dworzynski K, Bolton P, Plomin R (2010). Exploring the relation between prenatal and neonatal complications and later autistic-like features in a representative community sample of twins. Child Development 81, 166-182.
56. Schendel D, Bhasin TK (2008). Birth weight and gestational age characteristics of children with autism, including a comparison with other developmental disabilities. Pediatrics 121, 1155-1164.
57. Skranes J, Vangberg TR, Kulseng S, Indredavik MS, Evensen KA, Martinussen M, Dale AM, Haraldseth O, Brubakk AM (2007). Clinical findings and white matter abnormalities seen on diffusion tensor imaging in adolescents with very low birth weight. Brain 130, 654-666. (Pubitemid 46410747)
58. Spellacy WN, Handler A, Ferre CD (1990). A case-control study of 1253 twin pregnancies from a 1982-1987 perinatal data base. Obstetrics and Gynecology 75, 168-171. (Pubitemid 20062224)
59. Steffenburg S, Gillberg C, Hellgren L, Andersson L, Gillberg IC, Jakobsson G, Bohman M (1989). A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. Journal of Child Psychology and Psychiatry 30, 405-416. (Pubitemid 19131643)
60. Stokes ME, Davis CS, Koch GG (2000). Categorical Data Analysis Using the SAS System. SAS Institute Inc.: Cary, NC.
61. Szatmari P (2011). Is autism, at least in part, a disorder of fetal programming? Archives of General Psychiatry. Published online: 5 July 2011. doi:10.1001/archgenpsychiatry.2011.99.
62. Talbot GT, Goldstein RF, Nesbitt T, Johnson JL, Kay HH (1997). Is size discordancy an indication for delivery of preterm twins? American Journal of Obstetrics and Gynecology 177, 1050-1054. (Pubitemid 27525355)
63. Ward AJ (1990). A comparison and analysis of the presence of family problems during pregnancy of mothers of autistic children and mothers of normal children. Child Psychiatry and Human Development 20, 279-288. (Pubitemid 20342917)
64. Weiss LA, Arking DE; Gene Discovery Project of Johns Hopkins and the Autism Consortium, Daly MJ, Chakravarti A (2009). A genome-wide linkage and association scan reveals novel loci for autism. Nature 461, 802-808.
65. Weiss LA, Shen Y, Korn JM, Arking DE, Miller DT, Fossdal R, Saemundsen E, Stefansson H, Ferreira MA, Green T, Platt OS, Ruderfer DM, Walsh CA, Altshuler D, Chakravarti A, Tanzi RE, Stefansson K, Santangelo SL, Gusella JF, Sklar P, Wu BL, Daly MJ (2008). Association between microdeletion and microduplication at 16p11.2 and autism. New England Journal of Medicine 358, 667-675. (Pubitemid 351240746)
66. Zwaigenbaum L, Szatmari P, Jones MB, Bryson SE, Maclean JE, Mahoney WJ, Bartolucci G, Tuff L (2002). Pregnancy and birth complications in autism and liability to the broader autism phenotype. Journal of the American Academy of Child and Adolescent Psychiatry 41, 572-579. (Pubitemid 38338136)