Association of brain-derived neurotrophic factor (BDNF) haploinsufficiency with lower adaptive behaviour and reduced cognitive functioning in WAGR/11p13 deletion syndrome

Cortex

Volumn 49, Issue 10, 2013, Pages 2700-2710

  Han, Joan C ^a   Thurm, Audrey ^b   Golden Williams, Christine ^b   Joseph, Lisa A ^b   Zein, Wadih M ^c   Brooks, Brian P ^c   Butman, John A ^b   Brady, Sheila M ^a   Fuhr, Shannon R ^a   Hicks, Melanie D ^a   Huey, Amanda E ^a   Hanish, Alyson E ^a,d   Danley, Kristen M ^a   Raygada, Margarita J ^a   Rennert, Owen M ^a   Martinowich, Keri ^e   Sharp, Stephen J ^f   Tsao, Jack W ^f   Swedo, Susan E ^b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF NURSING RESEARCH   (United States)

^e LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

^f Uniformed Services University of the Health Sciences   (United States)

Author keywords

11p Deletion; Autism; Brain derived neurotrophic factor; IQ; WAGR syndrome

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADAPTIVE BEHAVIOR; ADOLESCENT; ADULT; ANIRIDIA; ARTICLE; AUTISM; AUTISM DIAGNOSTIC INTERVIEW REVISED; CHILD; CLINICAL ARTICLE; COGNITIVE DEFECT; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DISEASE SEVERITY; DNA MICROARRAY; FEMALE; GENETIC ASSOCIATION; HAPLOINSUFFICIENCY; HUMAN; INTELLIGENCE QUOTIENT; MALE; NEUROLOGIC EXAMINATION; PRESCHOOL CHILD; REFERENCE VALUE; SCHOOL CHILD; SCORING SYSTEM; SOCIAL BEHAVIOR; VINELAND ADAPTIVE BEHAVIOR COMPOSE SCORE; VISUAL ACUITY; WAGR SYNDROME;

11P DELETION; AUTISM; BRAIN-DERIVED NEUROTROPHIC FACTOR; IQ; WAGR SYNDROME;

ADAPTATION, PSYCHOLOGICAL; ADOLESCENT; ADULT; ANIRIDIA; AUTISTIC DISORDER; BEHAVIOR; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHILD; CHILD BEHAVIOR DISORDERS; CHILD, PRESCHOOL; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; COGNITION; COGNITION DISORDERS; COHORT STUDIES; CORPUS CALLOSUM; FEMALE; HAPLOINSUFFICIENCY; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; VISION TESTS; VISUAL ACUITY; WAGR SYNDROME; YOUNG ADULT;

EID: 84889675521     PISSN: 00109452     EISSN: 19738102     Source Type: Journal    
DOI: 10.1016/j.cortex.2013.02.009     Document Type: Article

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