Distinct activation phenotype of a highly conserved novel HLA-B57-restricted epitope during dengue virus infection

Immunology

Volumn 141, Issue 1, 2014, Pages 27-38

  Townsley, Elizabeth ^a   Woda, Marcia ^a   Thomas, Stephen J ^b   Kalayanarooj, Siripen ^c   Gibbons, Robert V ^d   Nisalak, Ananda ^d   Srikiatkhachorn, Anon ^a   Green, Sharone ^a   Stephens, Henry A F ^e   Rothman, Alan L ^f   Mathew, Anuja ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c Queen Sirikit National Institute for Child Health   (Thailand)

^d ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

CD71; CD8+ T cells; Dengue; HLA B57; Transferrin

Indexed keywords

CD69 ANTIGEN; CD71 ANTIGEN; HLA B57 ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NONSTRUCTURAL PROTEIN 1;

ADOLESCENT; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CHILD; CYTOTOXICITY; DENGUE; DENGUE VIRUS; HUMAN; IN VITRO STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; T LYMPHOCYTE ACTIVATION; VIRUS ISOLATION;

CD71; CD8+ T CELLS; DENGUE; HLA-B57; TRANSFERRIN;

ADOLESCENT; ANTIGENS, CD; CD8-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; DENGUE; DENGUE VIRUS; EPITOPES, T-LYMPHOCYTE; FEMALE; GENE EXPRESSION REGULATION; HLA-B ANTIGENS; HUMANS; INFANT; LYMPHOCYTE ACTIVATION; MALE; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84889669335     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12161     Document Type: Article

References (46)

1. Vaughn DW, Green S, Kalayanarooj S et al. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis 2000; 181:2-9.
2. Vaughn DW, Green S, Kalayanarooj S et al. Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis 1997; 176:322-30.
3. Sangkawibha N, Rojanasuphot S, Ahandrik S, Viriyapongse S, Jatanasen S, Salitul V, Phanthumachinda B, Halstead SB. Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak. Am J Epidemiol 1984; 120:653-69.
4. Nisalak A, Endy TP, Nimmannitya S et al. Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973 to 1999. Am J Trop Med Hyg 2003; 68:191-202.
5. Suwandono A, Kosasih H, Nurhayati et al. Four dengue virus serotypes found circulating during an outbreak of dengue fever and dengue haemorrhagic fever in Jakarta, Indonesia, during 2004. Trans R Soc Trop Med Hyg 2006; 100:855-62.
6. Anantapreecha S, Chanama S, A-nuegoonpipat A, Naemkhunthot S, Sa-Ngasang A, Sawanpanyalert P, Kurane I. Serological and virological features of dengue fever and dengue haemorrhagic fever in Thailand from 1999 to 2002. Epidemiol Infect 2005; 133:503-7.
7. Rothman AL. Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms. Nat Rev Immunol 2011; 11:532-43.
8. Halstead SB, O'Rourke EJ. Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody. J Exp Med 1977; 146:201-17.
9. Halstead SB, O'Rourke EJ. Antibody-enhanced dengue virus infection in primate leukocytes. Nature 1977; 265:739-41.
10. Kurane I, Rothman AL, Livingston PG et al. Immunopathologic mechanisms of dengue hemorrhagic fever and dengue shock syndrome. Arch Virol Suppl 1994; 9:59-64.
11. Srikiatkhachorn A, Green S. Markers of dengue disease severity. Curr Top Microbiol Immunol 2010; 338:67-82.
12. Mongkolsapaya J, Dejnirattisai W, Xu XN et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 2003; 9:921-7.
13. Green S, Pichyangkul S, Vaughn DW et al. Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever. J Infect Dis 1999; 180:1429-35.
14. Stephens HA, Klaythong R, Sirikong M et al. HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 2002; 60:309-18.
15. Vejbaesya S, Luangtrakool P, Luangtrakool K et al. TNF and LTA gene, allele, and extended HLA haplotype associations with severe dengue virus infection in ethnic Thais. J Infect Dis 2009; 199:1442-8.
16. Nguyen TP, Kikuchi M, Vu TQ et al. Protective and enhancing HLA alleles, HLA-DRB1*0901 and HLA-A*24, for severe forms of dengue virus infection, dengue hemorrhagic fever and dengue shock syndrome. PLoS Negl Trop Dis 2008; 2:e304.
17. Stephens HA. HLA and other gene associations with dengue disease severity. Curr Top Microbiol Immunol 2010; 338:99-114.
18. Borghans JA, Molgaard A, de Boer RJ, Kesmir C. HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24. PLoS ONE 2007; 2:e920.
19. Kim AY, Kuntzen T, Timm J et al. Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. Gastroenterology 2011; 140:686-96.
20. Stephens HA. HIV-1 diversity versus HLA class I polymorphism. Trends Immunol 2005; 26:41-7.
21. Illing PT, Vivian JP, Dudek NL et al. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature 2012; 486:554-8.
22. Reinherz EL. Pharmacology: A false sense of non-self. Nature 2012; 486:479-81.
23. Kosmrlj A, Read EL, Qi Y et al. Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. Nature 2010; 465:350-4.
24. Kalayanarooj S, Vaughn DW, Nimmannitya S et al. Early clinical and laboratory indicators of acute dengue illness. J Infect Dis 1997; 176:313-21.
25. Mathew A, Kurane I, Green S et al. Predominance of HLA-restricted cytotoxic T-lymphocyte responses to serotype-cross-reactive epitopes on nonstructural proteins following natural secondary dengue virus infection. J Virol 1998; 72:3999-4004.
26. Zivna I, Green S, Vaughn DW et al. T cell responses to an HLA-B*07-restricted epitope on the dengue NS3 protein correlate with disease severity. J Immunol 2002; 168:5959-65.
27. Anonymous. DHF: Diagnosis, Treament and Control. Geneva: WHO, 1997: 1-58.
28. van Panhuis WG, Gibbons RV, Endy TP, Rothman AL, Srikiatkhachorn A, Nisalak A, Burke DS, Cummings DA. Inferring the serotype associated with dengue virus infections on the basis of pre- and postinfection neutralizing antibody titers. J Infect Dis 2010; 202:1002-10.
29. Nightingale ZD, Patkar C, Rothman AL. Viral replication and paracrine effects result in distinct, functional responses of dendritic cells following infection with dengue 2 virus. J Leukoc Biol 2008; 84:1028-38.
30. Huebers HA, Finch CA. The physiology of transferrin and transferrin receptors. Physiol Rev 1987; 67:520-82.
31. + T cells from naturally acquired primary dengue virus infection are highly cross-reactive. Immunol Cell Biol 2011; 89:122-9.
32. Beaumier CM, Mathew A, Bashyam HS, Rothman AL. Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis 2008; 197:608-17.
33. Friberg H, Bashyam H, Toyosaki-Maeda T et al. Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans. Sci Rep 2011; 1:51.
34. Falconar AK, Young PR, Miles MA. Precise location of sequential dengue virus subcomplex and complex B cell epitopes on the nonstructural-1 glycoprotein. Arch Virol 1994; 137:315-26.
35. Alcon-LePoder S, Sivard P, Drouet MT, Talarmin A, Rice C, Flamand M. Secretion of flaviviral non-structural protein xml: from diagnosis to pathogenesis. Novartis Found Symp 2006; 277:233-47.
36. Janeway CA Jr, Travers P, Walport M, Shlomchik MJ. Immunobiology: The Immune System in Health and Disease, 5th edn. Antigen Recognition by T Cells. New York: Garland Science, 2001.
37. Lazaro E, Godfrey SB, Stamegna P, Ogbechie T, Kerrigan C, Zhang M, Walker BD, Le Gall S. Differential HIV epitope processing in monocytes and CD4 T cells affects cytotoxic T lymphocyte recognition. J Infect Dis 2009; 200:236-43.
38. + T cell responses in relation to commencement of capillary leakage in children with dengue. J Immunol 2010; 184:7281-7.
39. + T cell response. J Immunol 2009; 183:7919-30.
40. Neckers LM, Cossman J. Transferrin receptor induction in mitogen-stimulated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin 2. Proc Natl Acad Sci USA 1983; 80:3494-8.
41. May WS Jr, Cuatrecasas P. Transferrin receptor: its biological significance. J Membr Biol 1985; 88:205-15.
42. Batista A, Millan J, Mittelbrunn M, Sanchez-Madrid F, Alonso MA. Recruitment of transferrin receptor to immunological synapse in response to TCR engagement. J Immunol 2004; 172:6709-14.
43. Salmeron A, Borroto A, Fresno M, Crumpton MJ, Ley SC, Alarcon B. Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain. J Immunol 1995; 154:1675-83.
44. Bayer AL, Baliga P, Woodward JE. Transferrin receptor in T cell activation and transplantation. J Leukoc Biol 1998; 64:19-24.
45. Pattanapanyasat K, Hoy TG. Expression of cell surface transferrin receptor and intracellular ferritin after in vitro stimulation of peripheral blood T lymphocytes. Eur J Haematol 1991; 47:140-5.
46. Pelosi E, Testa U, Louache F, Thomopoulos P, Salvo G, Samoggia P, Peschle C. Expression of transferrin receptors in phytohemagglutinin-stimulated human T-lymphocytes. Evidence for a three-step model. J Biol Chem 1986; 261:3036-42.