Predominance of HLA-restricted cytotoxic T-lymphocyte responses to serotype-cross-reactive epitopes on nonstructural proteins following natural secondary dengue virus infection

Journal of Virology

Volumn 72, Issue 5, 1998, Pages 3999-4004

  Mathew, Anuja ^a   Kurane, Ichiro ^a,e   Green, Sharone ^a   Stephens, Henry A F ^b   Vaughn, David W ^c   Kalayanarooj, Siripen ^c   Suntayakorn, Saroj ^c   Chandanayingyong, Dasnayanee ^d   Ennis, Francis A ^a   Rothman, Alan L ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MIDDLESEX HOSPITAL   (United Kingdom)

^c MAHIDOL UNIVERSITY   (Thailand)

^d Kamphaeng Phet Provincial Hospital   (Thailand)

^e KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; HLA ANTIGEN; HLA B7 ANTIGEN;

ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENGUE; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; PRIORITY JOURNAL;

EID: 0031968530     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.5.3999-4004.1998     Document Type: Article

References (24)

1. Barber, L. D., and P. Parham. 1994. The essence of epitopes. J. Exp. Med. 180:1191-1194.
2. + human cytotoxic T lymphocytes. J. Virol. 63:5086-5091.
3. Chandanayingyong, D., H. A. F. Stephens, R. Klaythong, M. Sirikong, S. Udee, P. Longta, R. Chntangpol, S. Bejrachandra, and E. Rungruang. 1997. HLA-A, -DRB1, -DQA1 and -DQB1 polymorphism in Thais. Hum. Immunol. 53:174-182.
4. Chiewslip, P., R. Scott, and N. Bhamarapravati. 1981. Histocompatibility antigens and dengue hemorrhagic fever. Am. J. Trop. Med. Hyg. 30:1101-1105.
5. Falgout, B., R. Chanock, and C.-J. Lai. 1989. Proper processing of dengue virus nonstructural protein NS1 requires N terminal hydrophobic signal sequence and the downstream nonstructural protein NS2a. J. Virol. 63:1852.
6. + cytotoxic T-lymphocyte clones. J. Virol. 70:141-147.
7. + T-lymphocyte responses in a recipient of an experimental live-attenuated dengue virus type 1 vaccine: bulk culture proliferation, clonal analysis, and precursor frequency determination. J. Virol. 67:5962-5967.
8. Halstead, S. B. 1988. Immunological parameters of togavirus disease syndromes, p. 107-173. In R. W. Schlesinger (ed.), The togaviruses: biology, structure, replication. Academic Press, New York, N.Y.
9. Halstead, S. B., S. Nimmannitya, and S. N. Cohen. 1970. Observations related to the pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J. Biol. Med. 42:311-328.
10. Kalyanarooj, S., D. W. Vaughn, S. Nimmannitya, S. Green, S. Suntayakorn, N. Kunentrasai, W. Viramitrachai, S. Ratanachu-eke, S. Kiatpolpoj, B. L. Innis, A. L. Rothman, A. Nisalak, and F. A. Ennis. 1997. Early clinical and laboratory indicators of acute dengue illness. J. Infect. Dis. 176:313-321.
11. - cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones. J. Virol. 65: 1823-1828.
12. - cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones. J. Virol. 65: 1823-1828.
13. Kurane, I., D. Hebblewaite, Walter E. Brandt, and F. A. Ennis. 1984. Lysis of dengue virus-infected cells by natural cell-mediated cytotoxicity and antibody-dependent cell-mediated cytotoxicity. J. Virol. 52:223.
14. - cytotoxic T-cell clone. J. Virol. 67:6285-6288.
15. Kurane, I., and F. A. Ennis. 1992. Immunity and immunopathology in dengue virus infections. Semin. Immunol. 4:121-127.
16. Kurane, I., B. L. Innis, S. Nimmannitya, A. Nisalak, A. Meager, J. Janus, and F. A. Ennis. 1991. Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. J. Clin. Invest. 88:1473-1480.
17. + cytotoxic T lymphocyte (CTL) clones: recognition of NS3 amino acids 500-508 by CTL clones of two different specificities. J. Immunol. 154:1287-1295.
18. Lobigs, M., C. E. Arthur, A. Mullbacher, and R. V. Blanden. 1994. The flavivirus nonstructural protein NS3 is a dominant source of cytotoxic T cell peptide determinants. Virology 202:195-201.
19. + cytotoxic T lymphocytes of dengue virus nonstructural proteins NS3 and NS1.2a. J. Clin. Invest. 98: 1684-1692.
20. Sangdawibha, N., S. Rojanasuphot, S. Ahandrik, S. Viriyaponges, S. Jatanasen, V. Salitul, B. Phanthumachinda, and S. B. Halstead. 1984. Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. Am. J. Epidemiol. 120:653-669.
21. Sidney, J., H. M. Grey, R. T. Kubo, and A. Sette. 1996. Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs. Immunol. Today 17:261-266.
22. + T-cell clones. J. Virol. 70: 3108-3117.
23. Zhao, B., G. Prince, R. Horswood, K. H. Eckels, R. M. Chanock, and C.-J. Lai. 1989. Expression of dengue virus structural proteins and nonstructural protein NS1 by a recombinant vaccinia virus. J. Virol. 64:4109.
24. + T lymphocyte clones from Percoll-purified T lymphoblasts by stimulation with monoclonal antibody to CD3. J. Immunol. Methods 188:165-167.