Interaction of the antibiotic minocycline with liver mitochondria - Role of membrane permeabilization in the impairment of respiration

FEBS Journal

Volumn 280, Issue 24, 2013, Pages 6589-6599

  Schönfeld, Peter ^a   Siemen, Detlef ^a   Kreutzmann, Peter ^a   Franz, Claudia ^a   Wojtczak, Lech ^b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

minocyline; mitochondria; respiration; swelling; transmembrane potential

Indexed keywords

ALAMETHICIN; CYTOCHROME C; MINOCYCLINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; POTASSIUM CHLORIDE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PERMEABILIZATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; DRUG STRUCTURE; ENZYME METABOLISM; LIVER MITOCHONDRION; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

MINOCYLINE; MITOCHONDRIA; RESPIRATION; SWELLING; TRANSMEMBRANE POTENTIAL;

ALAMETHICIN; ANIMALS; ANTI-BACTERIAL AGENTS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELL RESPIRATION; CYTOCHROMES C; MEMBRANE POTENTIAL, MITOCHONDRIAL; MINOCYCLINE; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL SWELLING; NAD; OXYGEN CONSUMPTION; PHOSPHORYLATION; PROTON IONOPHORES; RATS; RATS, WISTAR;

RATTUS;

EID: 84889655281     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12563     Document Type: Article

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