Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition

Pharmacological Research

Volumn 65, Issue 1, 2012, Pages 120-128

  Cuenca Lopez, Maria D ^a   Karachitos, Andonis ^b   Massarotto, Luca ^c,d   Oliveira, Paulo J ^d   Aguirre, Norberto ^e   Galindo, María F ^f   Kmita, Hanna ^b   Jordán, Joaquin ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

^c UNIVERSITY OF PADOVA   (Italy)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF NAVARRA   (Spain)

^f CHUA   (Spain)

Author keywords

ANT; Mitochondria; Respiration; VDAC

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; MINOCYCLINE; VOLTAGE DEPENDENT ANION CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; LIPID BILAYER; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CELL RESPIRATION; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MINOCYCLINE; MITOCHONDRIA, LIVER; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; PERMEABILITY; RATS; RATS, WISTAR; TIME FACTORS; UNCOUPLING AGENTS; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84855986971     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.08.007     Document Type: Article

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