Reduced specificity of functional connectivity in the aging brain during task performance

Human Brain Mapping

Volumn 35, Issue 1, 2014, Pages 319-330

  Geerligs, Linda ^a,b   Maurits, Natasha M ^b   Renken, Remco J ^b   Lorist, Monicque M ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Aging; Dedifferentiation; FMRI; Functional connectivity; Neural noise

Indexed keywords

ADULT; AGING; ARTICLE; BOLD SIGNAL; BRAIN FUNCTION; BRAIN MATURATION; CELL DEDIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DEFAULT MODE NETWORK; DORSAL ATTENTION NETWORK; EXECUTIVE FUNCTION; FEMALE; FRONTAL OPERCULUM; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; INFERIOR PARIETAL LOBULE; INTELLIGENCE; MALE; MIDDLE FRONTAL GYRUS; MIDDLE TEMPORAL GYRUS; NERVE CELL NETWORK; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PSYCHOLOGIC TEST; STROOP TEST; SUPERIOR FRONTAL GYRUS; SUPERIOR PARIETAL LOBULE; SUPERIOR TEMPORAL GYRUS; TASK PERFORMANCE; WECHSLER INTELLIGENCE SCALE; WORKING MEMORY;

AGING; DEDIFFERENTIATION; FMRI; FUNCTIONAL CONNECTIVITY; NEURAL NOISE;

ADULT; AGED; AGING; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; YOUNG ADULT;

EID: 84889648443     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.22175     Document Type: Article

References (54)

1. Andrews-Hanna JR, Snyder AZ, Vincent JL, Lustig C, Head D, Raichle ME, Buckner RL (2007): Disruption of large-scale brain systems in advanced aging. Neuron 56:924-935.
2. Ashburner J (2007): A fast diffeomorphic image registration algorithm. Neuroimage 38:95-113.
3. Ashburner J, Friston KJ (2000): Voxel-based morphometry - The methods. Neuroimage 11:805-821.
4. Baltes PB, Lindenberger U (1997): Emergence of a powerful connection between sensory and cognitive functions across the adult life span: A new window to the study of cognitive aging?Psychol Aging 12:12-21.
5. Beckmann CF, DeLuca M, Devlin JT, Smith SM (2005): Investigations into resting-state connectivity using independent component analysis. Phil Trans R Soc B 360:1001-1013.
6. Biswal BB, Eldreth DA, Motes MA, Rypma B (2010): Task-dependent individual differences in prefrontal connectivity. Cereb Cortex 20:2188-2197.
7. Buckner RL, Andrews-Hanna JR, Schacter DL (2008): The brain's default network: Anatomy, function, and relevance to disease. Ann NY Acad Sci 1124:1-38.
8. Carp J, Gmeindl L, Reuter-Lorenz PA (2010): Age differences in the neural representation of working memory revealed by multi-voxel pattern analysis. Front Human Neurosci 4:217.
9. Carp J, Park J, Hebrank A, Park DC, Polk TA (2011a): Age-related neural dedifferentiation in the motor system. PLoS One 6:e29411.
10. Carp J, Park J, Polk TA, Park DC (2011b)Age differences in neural distinctiveness revealed by multi-voxel pattern analysis. Neuroimage 56:736-743.
11. Casanova R, Srikanth R, Baer A, Laurienti PJ, Burdette JH, Hayasaka S, Flowers L, Wood F, Maldjian JA (2007): Biological parametric mapping: A statistical toolbox for multimodality brain image analysis. Neuroimage 34:137-143.
12. Damoiseaux JS, Beckmann CF, Arigita EJS, Barkhof F, Scheltens P, Stam CJ, Smith SM, Rombouta SARB (2008): Reduced resting-state brain activity in the 'default network' in normal aging. Cereb Cortex 18:1856-1864.
13. Damoiseaux JS, Rombouts SARB, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF (2006): Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 103:13848-13853.
14. de Graaf A, Deelman BG.1991. De Cognitive Screening Test: Handleiding [The Cognitive Screening Test: Manual].Lisse, The Netherlands:Swets en Zeitlinger b.v.
15. Deco G, Jirs V, McIntosh AR, Sporns O, Kötter R (2009): Key role of coupling, delay, and noise in resting brain fluctuations. Proc Natl Acad Sci USA 106:10302-10307.
16. Ding C, He X (2004): K-means clustering via principal component analysis. In: Proceedings of the International Machine Learning Conference (ICML), Banff, Canada, July 2004.
17. Dosenbach NUF, Fair DA, Miezin FM, Cohen AL, Wenger KK, Dosenbach RAT, Fox MD, Snyder AZ, Vincent JL, Raichle ME, Schlaggar BL, Petersen SE (2007): Distinct brain networks for adaptive and stable task control in humans. Proc Natl Acad Sci USA 104:11073-11078.
18. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME (2005): The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA 102:9673-9678.
19. Friston KJ, Williams S, Howard R, Frackowiak RSJ, Turner R (1996): Movement-related effects in fMRI time-series. Magn Reson Med 35:346-355.
20. Geerligs L, Saliasi E, Maurits NM, Lorist MM: Compensation through increased functional connectivity: Neural correlates of inhibition in old and young. J Cogn Neurosci (in press).
21. Good CD, Johnsrude IS, Ashburner J, Henson RNA, Friston KJ, Frackowiak RSJ (2001): A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 14:21-36.
22. Grady CL, Protzner AB, Kovacevic N, Strother SC, Afshin-Pour B, Wojtowicz M, Anderson JAE, Churchill N, McIntosh AR (2010): A multivariate analysis of age-related differences in default mode and task-positive networks across multiple cognitive domains. Cereb Cortex 20:1432-1447.
23. Greicius MD, Krasnow B, Reiss AL, Menon V (2003): Functional connectivity in the resting brain: A network analysis of the default mode hypothesis. Proc Natl Acad Sci USA 100:253-258.
24. Hampson M, Driesen N, Roth JK, Gore JC, Constable RT (2010): Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance. Magn Reson Imaging 28:1051-1057.
25. Kalkstein J, Checksfield K, Bollinger J, Gazzaley A (2011): Diminished top-down control underlies a visual imagery deficit in normal aging. J Neurosci 31:15768-15774.
26. Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP (2008): Competition between functional brain networks mediates behavioral variability. Neuroimage 39:527-537.
27. Kiehl KA, Stevens MC, Laurens KR, Pearlson G, Calhoun VD, Liddle PF (2005): An adaptive reflexive processing model of neurocognitive function: Supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task. Neuroimage 25:899-915.
28. Kokal I, Gazzola V, Keysers C (2009): Acting together in and beyond the mirror neuron system. Neuroimage 47:2046-2056.
29. Lezak MD, Howieson DB, Loring DD, Hannay HJ, Fisher JS (2004): Neuropsychological Assessment.New York:Oxford University Press.
30. Li S-, Lindenberger U, Sikström S (2001): Aging cognition: From neuromodulation to representation. Trends Cogn Sci 5:479-486.
31. Oakes TR, Fox AS, Johnstone T, Chung MK, Kalin N, Davidson RJ (2007): Integrating VBM into the general linear model with voxelwise anatomical covariates. Neuroimage 34:500-508.
32. Park DC, Reuter-Lorenz P (2009): The adaptive brain: Aging and neurocognitive scaffolding. Annu Rev Psychol 60:173-196.
33. Park DC, Polk TA, Park R, Minear M, Savage A, Smith MR (2004): Aging reduces neural specialization in ventral visual cortex. Proc Natl Acad Sci USA 101:13091-13095.
34. Park J, Carp J, Hebrank A, Park DC, Polk TA (2010): Neural specificity predicts fluid processing ability in older adults. J Neurosci 30:9253-9259.
35. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001): A default mode of brain function. Proc Natl Acad Sci USA 98:676-682.
36. Reitan RM (1958): Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 8:271-276.
37. Rieckmann A, Karlsson S, Fischer H, Bäckman L (2011): Caudate dopamine D1 receptor density is associated with individual differences in frontoparietal connectivity during working memory. J Neurosci 31:14284-14290.
38. Rosazza C, Minati L (2011): Resting-state brain networks: Literature review and clinical applications. Neurol Sci 32:773-785.
39. Sambataro F, Murty VP, Callicott JH, Tan H-, Das S, Weinberger DR, Mattay VS (2010): Age-related alterations in default mode network: Impact on working memory performance. Neurobiol Aging 31:839-852.
40. Sporns O, Chialvo DR, Kaiser M, Hilgetag CC (2004): Organization, development and function of complex brain networks. Trends Cogn Sci 8:418-425.
41. Spreng RN, Schacter DL: Default network modulation and large-scale network interactivity in healthy young and old adults. Cereb. Cortex (in press).
42. Spreng RN, Stevens WD, Chamberlain JP, Gilmore AW, Schacter DL (2010): Default network activity, coupled with the frontoparietal control network, supports goal-directed cognition. Neuroimage 53:303-317.
43. Steffener J, Tabert M, Reuben A, Stern Y (2010): Investigating hemodynamic response variability at the group level using basis functions. Neuroimage 49:2113-2122.
44. Stroop JR (1935): Studies of interference in serial verbal reactions. J Exp Psychol 18:643-662.
45. Tombaugh TN (2004): Trail Making Test A and B: Normative data stratified by age and education. Arch Clin Neuropsychol 19:203-214.
46. Toro R, Fox PT, Paus T (2008): Functional coactivation map of the human brain. Cereb Cortex 18:2553-2559.
47. Van Dijk KRA, Hedden T, Venkataraman A, Evans KC, Lazar SW, Buckner RL (2010): Intrinsic functional connectivity as a tool for human connectomics: Theory, properties, and optimization. J Neurophysiol 103:297-321.
48. Van Essen DC, Drury HA, Dickson J, Harwell J, Hanlon D, Anderson CH (2001): An integrated software suite for surface-based analyses of cerebral cortex. J Am Med Inform Assoc 8:443-459.
49. Vincent JL, Kahn I, Snyder AZ, Raichle ME, Buckner RL (2008): Evidence for a frontoparietal control system revealed by intrinsic functional connectivity. J Neurophysiol 100:3328-3342.
50. Voss MW, Prakash RS, Erickson KI, Basak C, Chaddock L, Kim JS, Alves H, Heo S, Szabo A, White SM, Wojcicki TR, Mailey EL, Gothe N, Olson EA, McAuley E, Kramer AF (2010): Plasticity of brain networks in a randomized intervention trial of exercise training in older adults. Front Ag Neurosci 2:1-17.
51. Wechsler D (1981): Wechsler Adult Intelligence Scale-Revised Manual.New York:Psychological Corporation.
52. Wen X, Yao L, Liu Y, Ding M (2012): Causal interactions in attention networks predict behavioral performance. J Neurosci 32:1284-1292.
53. Wilson BA, Alderman N, Burgess PW, Emslie H, Evans JJ (1996): Behavioural Assessment of the Dysexecutive Syndrome.Bury St Edmunds, UK:Thames Valley Test Company.
54. Wu T, Zang Y, Wang L, Long X, Hallett M, Chen Y, Li K, Chan P (2007): Aging influence on functional connectivity of the motor network in the resting state. Neurosci Lett 422:164-168.