Positron emission tomography study on pancreatic somatostatin receptors in normal and diabetic rats with 68Ga-DOTA-octreotide: A potential PET tracer for beta cell mass measurement

Biochemical and Biophysical Research Communications

Volumn 442, Issue 1-2, 2013, Pages 79-84

  Sako, Takeo ^a,b,c   Hasegawa, Koki ^a   Nishimura, Mie ^a   Kanayama, Yousuke ^a   Wada, Yasuhiro ^a   Hayashinaka, Emi ^a   Cui, Yilong ^a   Kataoka, Yosky ^a   Senda, Michio ^a,b,c   Watanabe, Yasuyoshi ^a  

^a RIKEN   (Japan)

^b INSTITUTE OF BIOMEDICAL RESEARCH AND INNOVATION   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

68Ga DOTA octreotide; Diabetes mellitus; Pancreatic beta cell mass; Positron emission tomography; Somatostatin receptor

Indexed keywords

OCTREOTIDE; SOMATOSTATIN RECEPTOR; TETRAXETAN OCTREOTIDE GA 68; TRACER; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA CELL MASS; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ACCUMULATION; ISOTOPE LABELING; MALE; MICROWAVE IRRADIATION; MOLECULAR IMAGING; NONHUMAN; PANCREAS ISLET BETA CELL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RAT;

RATTUS;

(68)GA-DOTA-OCTREOTIDE; AC; ADENYLYL CYCLASE; BCM; BETA CELL MASS; DIABETES MELLITUS; DIHYDROTETRABENAZINE; DOTA-OC; DTBZ; FBP; FILTERED BACK-PROJECTION; FORE; FOURIER REBINNING; GLP-1; GLUCAGON-LIKE PEPTIDE-1; ID; INJECTED DOSE; MAP; MAXIMUM A POSTERIORI; PANCREATIC BETA CELL MASS; POSITRON EMISSION TOMOGRAPHY; SOMATOSTATIN RECEPTOR; SSTR; STREPTOZOTOCIN; STZ; VOI; VOLUMETRIC REGION OF INTEREST;

ANIMALS; CELL COUNT; DIABETES MELLITUS; GALLIUM RADIOISOTOPES; INSULIN-SECRETING CELLS; MALE; OCTREOTIDE; ORGANOMETALLIC COMPOUNDS; PANCREAS; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN;

EID: 84889648390     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.11.001     Document Type: Article

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