Evidence of reduced β-cell function in Asian Indians with mild dysglycemia

Diabetes Care

Volumn 36, Issue 9, 2013, Pages 2772-2778

  Staimez, Lisa R ^a   Weber, Mary Beth ^b   Ranjani, Harish ^c   Ali, Mohammed K ^a,b   Echouffo Tcheugui, Justin B ^b   Phillips, Lawrence S ^d,e   Mohan, Viswanathan ^c   Venkat Narayan, K M ^a,b,f  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY   (United States)

^c MADRAS DIABETES RESEARCH FOUNDATION   (India)

^d EMORY UNIVERSITY   (United States)

^e ATLANTA VA MEDICAL CENTER   (United States)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ARTICLE; BODY MASS; CELL FUNCTION; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOWN REGULATION; DYSGLYCEMIA; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INDIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRACTICE GUIDELINE; WAIST CIRCUMFERENCE;

ADIPOSITY; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INDIA; INSULIN-SECRETING CELLS; MALE;

EID: 84889633240     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-2290     Document Type: Article

References (40)

1. International Diabetes Federation. The Diabetes Atlas. 5th ed. Brussels, Belgium, International Diabetes Federation, 2011
2. DeFronzo RA. Glucose intolerance and aging. Diabetes Care 1981;4: 493-501
3. Saad MF, Knowler WC, Pettitt DJ, Nelson RG, Charles MA, Bennett PH. A two-step model for development of non-insulindependent diabetes. Am J Med 1991;90: 229-235
4. Goldstein BJ. Insulin resistance as the core defect in type 2 diabetes mellitus. Am J Cardiol 2002;90:3G-10G
5. Amati F, Dubé JJ, Coen PM, Stefanovic- Racic M, Toledo FG, Goodpaster BH. Physical inactivity and obesity underlie the insulin resistance of aging. Diabetes Care 2009;32: 1547-1549
6. Gerich JE. Contributions of insulinresistance and insulin-secretory defects to the pathogenesis of type 2 diabetes mellitus. Mayo Clinic Proc 2003;78: 447-456
7. Sjaarda LA, Michaliszyn SF, Lee S, Tfayli H, Bacha F, Farchoukh L, Arslanian SA. HbA1c diagnostic categories and beta-cell function relative to insulin sensitivity in overweight/obese adolescents. Diabetes Care 2012;35: 2559-2563
8. Cnop M, Vidal J, Hull RL, et al. Progressive loss of beta-cell function leads to worsening glucose tolerance in firstdegree relatives of subjects with type 2 diabetes. Diabetes Care 2007;30: 677-682
9. Cali AM, Man CD, Cobelli C, et al. Primary defects in beta-cell function further exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents. Diabetes Care 2009;32: 456-461
10. Faerch K, Vaag A, Holst JJ, Hansen T, Jørgensen T, Borch-Johnsen K. Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study. Diabetes Care 2009;32: 439-444
11. Elbein SC. Genetics factors contributing to type 2 diabetes across ethnicities. J Diabetes Sci Tech 2009;3: 685-689
12. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444: 840-846
13. Anjana RM, Pradeepa R, Deepa M, et al.; ICMR-INDIAB Collaborative Study Group. Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: phase I results of the Indian Council of Medical Research-INdia DIABetes (ICMRINDIAB) study. Diabetologia 2011;54: 3022-3027
14. Chan JC, Malik V, Jia W, et al. Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA 2009;301: 2129-2140
15. Mohan V, Sharp PS, Cloke HR, Burrin JM, Schumer B, Kohner EM. Serum immunoreactive insulin responses to a glucose load in Asian Indian and European type 2 (non-insulin-dependent) diabetic patients and control subjects. Diabetologia 1986; 29: 235-237
16. Dowse GK, Zimmet PZ, Alberti KG, et al.; Mauritius NCD Study Group. Serum insulin distributions and reproducibility of the relationship between 2-hour insulin and plasma glucose levels in Asian Indian, Creole, and Chinese Mauritians. Metabolism 1993;42: 1232-1241
17. Dowse GK, Qin H, Collins VR, Zimmet PZ, Alberti KG, Gareeboo H; The Mauritius NCD Study Group. Determinants of estimated insulin resistance and beta-cell function in Indian, Creole and Chinese Mauritians. Diabetes Res Clin Pract 1990; 10: 265-279
18. Snehalatha C, Ramachandran A, Satyavani K, Latha E, Viswanathan V. Study of genetic prediabetic south Indian subjects. Importance of hyperinsulinemia and betacell dysfunction. Diabetes Care 1998;21: 76-79
19. Snehalatha C, Satyavani K, Sivasankari S, Vijay V, Ramachandran A. Insulin secretion and action in different stages of glucose tolerance in Asian Indians. Diabetic Med 1999;16:408-414
20. Snehalatha C, Ramachandran A, Sivasankari S, Satyavani K, Vijay V. Insulin secretion and action show differences in impaired fasting glucose and in impaired glucose tolerance in Asian Indians. Diabetes Metab Res Rev 2003;19: 329-332
21. Bergman RN, Phillips LS, Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 1981; 68: 1456-1467
22. Weber MB, Ranjani H, Meyers GC, Mohan V, Narayan KM. A model of translational research for diabetes prevention in low and middle-income countries: The Diabetes Community Lifestyle Improvement Program (D-CLIP) trial. Prim Care Diabetes 2012;6: 3-9
23. Utzschneider KM, Prigeon RL, Faulenbach MV, et al. Oral disposition index predicts the development of future diabetes above and beyond fasting and 2- h glucose levels. Diabetes Care 2009;32: 335-341
24. World HealthOrganization.WHOExpert Committee on Diabetes Mellitus: second report.World Health Organ Tech Rep Ser 1980;646: 1-80
25. American Diabetes Association. Standards of medical care in diabetesd2010. Diabetes Care 2010;33(Suppl 1):S11-S61
26. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28: 412-419
27. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22: 1462-1470
28. DeFronzo RA, Matsuda M. Reduced time points to calculate the composite index. Diabetes Care 2010;33:e93
29. WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;363: 157-163
30. International Diabetes Federation. The IDF Consensus worldwide definition of the metabolic syndrome. Brussels, Belgium, International Diabetes Federation, 2006
31. Retnakaran R, Shen S, Hanley AJ, Vuksan V, Hamilton JK, Zinman B. Hyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test. Obesity (Silver Spring) 2008;16: 1901-1907
32. Retnakaran R, Qi Y, Goran MI, Hamilton JK. Evaluation of proposed oral disposition index measures in relation to the actual disposition index. Diabetic Med 2009;26:1198-1203
33. Miyazaki Y, Akasaka H, Ohnishi H, Saitoh S, DeFronzo RA, Shimamoto K. Differences in insulin action and secretion, plasma lipids and blood pressure levels between impaired fasting glucose and impaired glucose tolerance in Japanese subjects. Hypertens Res 2008;31: 1357-1363
34. Bi Y, Zhu D, Jing Y, et al. Decreased beta cell function and insulin sensitivity contributed to increasing fasting glucose in Chinese. Acta Diabetol 2012;49(Suppl 1): S51-S58
35. Szoke E, Shrayyef MZ, Messing S, et al. Effect of aging on glucose homeostasis: accelerated deterioration of beta-cell function in individuals with impaired glucose tolerance. Diabetes Care 2008;31: 539-543
36. Slentz CA, Tanner CJ, Bateman LA, et al. Effects of exercise training intensity on pancreatic beta-cell function. Diabetes Care 2009;32: 1807-1811
37. Kanat M, Mari A, Norton L, et al. Distinct b-cell defects in impaired fasting glucose and impaired glucose tolerance. Diabetes 2012;61: 447-453
38. Weyer C, Bogardus C, Pratley RE. Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose tolerance. Diabetes 1999;48: 2197-2203
39. Hong J, Gui MH, Gu WQ, Zhang YF, Xu M, Chi ZN, Zhang Y, Li XY, Wang WQ, Ning G. Differences in insulin resistance and pancreatic B-cell function in obese subjects with isolated impaired glucose tolerance and isolated impaired fasting glucose. Diabetic Med 2008;25: 73-79
40. Utzschneider KM, Prigeon RL, Tong J, et al. Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studies. Diabetologia 2007;50: 2516-2525