Impulsivity is associated with uric acid: Evidence from humans and mice

Biological Psychiatry

Volumn 75, Issue 1, 2014, Pages 31-37

  Sutin, Angelina R ^a,b   Cutler, Roy G ^b   Camandola, Simonetta ^b   Uda, Manuela ^c   Feldman, Neil H ^b   Cucca, Francesco ^c   Zonderman, Alan B ^b   Mattson, Mark P ^b,d   Ferrucci, Luigi ^a   Schlessinger, David ^b   Terracciano, Antonio ^a,b  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c CNR   (Italy)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Excitement seeking; impulse control; impulsivity; mouse model; personality traits; uric acid

Indexed keywords

URIC ACID;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY DISORDER; ARTICLE; BIPOLAR DISORDER; COMMUNITY SAMPLE; CONTROLLED STUDY; DEPRESSION; EMOTION; EXCITEMENT; FEMALE; HUMAN; IMPULSIVENESS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PERSONALITY TEST; PRIORITY JOURNAL; REVISED NEO PERSONALITY INVENTORY; SCHIZOPHRENIA; SELF REPORT; URIC ACID BLOOD LEVEL; WILD TYPE;

EXCITEMENT SEEKING; IMPULSE CONTROL; IMPULSIVITY; MOUSE MODEL; PERSONALITY TRAITS; URIC ACID;

ADULT; AGED; ANIMALS; COHORT STUDIES; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; HUMANS; IMPULSIVE BEHAVIOR; MALE; MAZE LEARNING; MENTAL DISORDERS; MICE; MICE, TRANSGENIC; MIDDLE AGED; PERSONALITY INVENTORY; TIME FACTORS; URATE OXIDASE; URIC ACID;

EID: 84889604946     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.02.024     Document Type: Article

References (52)

1. F.G. Moeller, E.S. Barratt, D.M. Dougherty, J.M. Schmitz, and A.C. Swann Psychiatric aspects of impulsivity Am J Psychiatry 158 2001 1783 1793
2. L. Bevilacqua, S. Doly, J. Kaprio, Q. Yuan, R. Tikkanen, and T. Paunio A population-specific HTR2B stop codon predisposes to severe impulsivity Nature 468 2010 1061 1066
3. A. Terracciano, T. Esko, A.R. Sutin, M.H. de Moor, O. Meirelles, and G. Zhu Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking Transl Psychiatry 1 2011 e49
4. S. Kim, and D. Lee Prefrontal cortex and impulsive decision making Biol Psychiatry 69 2011 1140 1146
5. D.I. Feig, D.H. Kang, and R.J. Johnson Medical progress: Uric acid and cardiovascular risk N Engl J Med 359 2008 1811 1821
6. Z.F. Yu, A.J. Bruce-Keller, Y. Goodman, and M.P. Mattson Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo J Neurosci Res 53 1998 613 625
7. S. Guerreiro, A. Ponceau, D. Toulorge, E. Martin, D. Alvarez-Fischer, E.C. Hirsch, and P.P. Michel Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: Potentiation by low-level depolarization J Neurochem 109 2009 1118 1128
8. P. Manowitz, L.F. Amorosa, H.S. Goldstein, and P.L. Carlton Uric acid level increases in humans engaged in gambling: A preliminary report Biol Psychol 36 1993 223 229
9. C.M. Barrera, Z.R. Ruiz, and W.P. Dunlap Uric acid: A participating factor in the symptoms of hyperactivity Biol Psychiatry 24 1988 344 347
10. R.J. Johnson, M.S. Gold, D.R. Johnson, T. Ishimoto, M.A. Lanaspa, N.R. Zahniser, and N.M. Avena Attention-deficit/hyperactivity disorder: Is it time to reappraise the role of sugar consumption? Postgrad Med 123 2011 39 49
11. M. Rösler, R. Fischer, R. Ammer, C. Ose, and W. Retz A randomised, placebo-controlled, 24-week, study of low-dose extended-release methylphenidate in adults with attention-deficit/hyperactivity disorder Eur Arch Psychiatry Clin Neurosci 259 2009 120 129
12. G. Salvadore, C.I. Viale, D.A. Luckenbaugh, V.C. Zanatto, L.V. Portela, and D.O. Souza Increased uric acid levels in drug-naive subjects with bipolar disorder during a first manic episode Prog Neuropsychopharmacol Biol Psychiatry 34 2010 819 821
13. D.J. Schretlen, J. Ward, S.M. Meyer, J. Yun, J.G. Puig, and W.L. Nyhan Behavioral aspects of Lesch-Nyhan disease and its variants Dev Med Child Neurol 47 2005 673 677
14. J.A. Gray, and N. McNaughton The Neuropsychology of Anxiety 2000 Oxford University Press Oxford, UK
15. P.J. Corr Reinforcement sensitivity theory and personality Neurosci Biobehav Rev 28 2004 317 332
16. A.E. Skodol Personality disorders in DSM-5 Annu Rev Clin Psychol 8 2012 317 844
17. S.P. Whiteside, and D.R. Lynam The five factor model and impulsivity: Using a structural model of personality to understand impulsivity Pers Individ Dif 30 2001 669 689
18. P.T. Costa Jr, and R.R. McCrae Revised NEO Personality Inventory (NEO-PI-R) and the NEO Five-Factor Inventory (NEO-FFI) Professional Manual 1992 Psychological Assessment Resources Odessa, FL
19. T.M. Lorenzi, D.L. Borba, G. Dutra, and D.R. Lara Association of serum uric acid levels with emotional and affective temperaments J Affect Disord 121 2010 161 164
20. A. Terracciano, and P.T. Costa Jr Smoking and the Five-Factor Model of personality Addiction 99 2004 472 481
21. A.R. Sutin, F. Ferrucci, A.B. Zonderman, and A. Terracciano Personality and obesity across the adult lifespan J Pers Soc Psychol 101 2011 579 592
22. R.L. Johnson The Fat Switch 2012 Mercola.com Chicago
23. D. Haj Mouhamed, A. Ezzaher, F. Neffati, W. Douki, L. Gaha, and M.F. Najjar Effect of cigarette smoking on plasma uric acid concentrations Environ Health Prev Med 16 2011 307 312
24. A. Terracciano, R.R. McCrae, L.J. Brant, and P.T. Costa Jr Hierarchical linear modeling analyses of the NEO-PI-R scales in the Baltimore Longitudinal Study of Aging Psychol Aging 20 2005 493 506
25. J. Lee, D. Sparrow, P.S. Vokonas, L. Landsberg, and S.T. Weiss Uric acid and coronary heart disease risk: Evidence for a role of uric acid in the obesity-insulin resistance syndrome. The Normative Aging Study Am J Epidemiol 142 1995 288 294
26. G. Pilia, W.M. Chen, A. Scuteri, M. Orrú, G. Albai, and M. Dei Heritability of cardiovascular and personality traits in 6,148 Sardinians PLoS Genet 2 2006 1207 1223
27. P.T. Costa, A. Terracciano, M. Uda, L. Vacca, C. Mameli, and G. Pilia Personality traits in Sardinia: Testing founder population effects on trait means and variances Behav Genet 37 2007 376 387
28. K.J. Preacher, and A.F. Hayes Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models Behav Res Methods 40 2008 879 891
29. L.S. Aiken, and S.G. West Multiple Regression: Testing and Interpreting Interactions 1991 Sage Thousand Oaks, CA
30. X. Wu, M. Wakamiya, S. Vaishnav, R. Geske, C. Montgomery Jr, and P. Jones Hyperuricemia and urate nephropathy in urate oxidase-deficient mice Proc Natl Acad Sci U S A 91 1994 742 746
31. T. Lyngdoh, P. Marques-Vidal, F. Paccaud, M. Preisig, G. Waeber, M. Bochud, and P. Vollenweider Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study PLoS One 6 2011 e19901
32. A.R. Sutin, A. Terracciano, B. Deiana, S. Naitza, L. Ferrucci, and M. Uda High neuroticism and low conscientiousness are associated with interleukin-6 Psychol Med 40 2010 1485 1493
33. F. Dellu, P.V. Piazza, W. Mayo, M. Le Moal, and H. Simon Novelty-seeking in rats - biobehavioral characteristics and possible relationship with the sensation-seeking trait in man Neuropsychobiology 34 1996 136 145
34. D. Belin, N. Berson, E. Balado, P.V. Piazza, and V. Deroche-Gamonet High-novelty-preference rats are predisposed to compulsive cocaine self-administration Neuropsychopharmacology 36 2011 569 579
35. C.R. Pawlak, and R.K.W. Schwarting Object preference and nicotine consumption in rats with high vs. low rearing activity in a novel open field Pharmacol Biochem Behav 73 2002 679 687
36. A. Borta, and R.K.W. Schwarting Post-trial treatment with the nicotinic agonist metanicotine: Differential effects in Wistar rats with high versus low rearing activity Pharmacol Biochem Behav 80 2005 541 548
37. C.J. Hopwood, L.C. Morey, A.E. Skodol, R.L. Stout, S. Yen, and E.B. Ansell Five-factor model personality traits associated with alcohol-related diagnoses in a clinical sample J Stud Alcohol Drugs 68 2007 455 460
38. R.M. Bagby, D.D. Vachon, E.L. Bulmash, T. Toneatto, L.C. Quilty, and P.T. Costa Pathological gambling and the five-factor model of personality Pers Individ Dif 43 2007 873 880
39. U. Hegerl, H. Himmerich, B. Engmann, and T. Hensch Mania and attention-deficit/hyperactivity disorder: Common symptomatology, common pathophysiology and common treatment? Curr Opin Psychiatry 23 2010 1 7
40. C.M. Barrera, R.E. Hunter, and W.P. Dunlap Hyperuricemia and locomotor activity in developing rats Pharmacol Biochem Behav 33 1989 367 369
41. C.R. Powell, M.L. Stoller, B.F. Schwartz, C. Kane, D.L. Gentle, J.E. Bruce, and S.W. Leslie Impact of body weight on urinary electrolytes in urinary stone formers Urology 55 2000 825 830
42. A.J. Saliba, K. Wragg, and P. Richardson Sweet taste preference and personality traits using a white wine Food Qual Prefer 20 2009 572 575
43. J. Perheentupa, and K. Raivio Fructose-induced hyperuricaemia Lancet 2 1967 528 531
44. R.J. Johnson, Y.Y. Sautin, W.J. Oliver, C. Roncal, W. Mu, and L. Gabriela Sanchez-Lozada Lessons from comparative physiology: Could uric acid represent a physiologic alarm signal gone awry in western society? J Comp Physiol B 179 2009 67 76
45. H. Hashimoto, N. Shintani, K. Tanaka, W. Mori, M. Hirose, and T. Matsuda Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP) Proc Natl Acad Sci U S A 98 2001 13355 13360
46. N. Shintani, H. Hashimoto, K. Tanaka, N. Kawagishi, C. Kawaguchi, and M. Hatanaka Serotonergic inhibition of intense jumping behavior in mice lacking PACAP (Adcyap1-/-) Ann N Y Acad Sci 1070 2006 545 549
47. T.Y.C. Pang, X. Du, M.S. Zajac, M.L. Howard, and A.J. Hannan Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease Hum Mol Genet 18 2009 753 766
48. F. Mochel, B. Durant, A. Durr, and R. Schiffmann Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice PLoS One 6 2011 e18336
49. M.G. García, J.G. Puig, and R.J. Torres Adenosine, dopamine and serotonin receptors imbalance in lymphocytes of Lesch-Nyhan patients J Inherit Metab Dis 2012 2012 1 7
50. M. Bertelli, B. Alushi, A. Veicsteinas, H.A. Jinnah, and V. Micheli Gene expression and mRNA editing of serotonin receptor 2C in brains of HPRT gene knock-out mice, an animal model of Lesch-Nyhan disease J Clin Neurosci 16 2009 1061 1063
51. Y. Suwazono, E. Kobayashi, M. Uetani, K. Miura, Y. Morikawa, and M. Ishizaki The -1438A/G polymorphism in the 5-hydroxytryptamine receptor 2A gene is related to hyperuricemia, increased γ-glutamyl transpeptidase and decreased high-density lipoprotein cholesterol level in the Japanese population: A prospective cohort study over 5 years Int J Mol Med 17 2006 77 82
52. D.D. Lam, A.S. Garfield, O.J. Marston, J. Shaw, and L.K. Heisler Brain serotonin system in the coordination of food intake and body weight Pharmacol Biochem Behav 97 2010 84 91