Activation of GABAergic neurons in the interpeduncular nucleus triggers physical nicotine withdrawal symptoms

Current Biology

Volumn 23, Issue 23, 2013, Pages 2327-2335

  Zhao Shea, Rubing ^a   Liu, Liwang ^a   Pang, Xueyan ^a   Gardner, Paul D ^a   Tapper, Andrew R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUS; RODENTIA;

4 AMINOBUTYRIC ACID RECEPTOR; GLUTAMIC ACID; MECAMYLAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE PROTEIN; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; RHODOPSIN; SOMATOSTATIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; DRUG ANTAGONISM; GENETICS; LIGHT; MALE; METABOLISM; METHODOLOGY; MOUSE; PHOTOTHERAPY; PHYSIOLOGY; RADIATION EXPOSURE; SECRETION (PROCESS); SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE; WITHDRAWAL SYNDROME;

ANIMALS; GABAERGIC NEURONS; GLUTAMIC ACID; LIGHT; MALE; MECAMYLAMINE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PHOTOTHERAPY; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NICOTINIC; RHODOPSIN; SOMATOSTATIN; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPTIC TRANSMISSION;

EID: 84889581058     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2013.09.041     Document Type: Article

References (33)

1. M.R. Picciotto, and P.J. Kenny Molecular mechanisms underlying behaviors related to nicotine addiction Cold Spring Harb Perspect Med 3 2013 a012112
2. N.L. Benowitz Neurobiology of nicotine addiction: implications for smoking cessation treatment Am. J. Med. 121 Suppl 1 2008 S3 S10
3. P.J. Kenny, and A. Markou Neurobiology of the nicotine withdrawal syndrome Pharmacol. Biochem. Behav. 70 2001 531 549
4. M.I. Damaj, W. Kao, and B.R. Martin Characterization of spontaneous and precipitated nicotine withdrawal in the mouse J. Pharmacol. Exp. Ther. 307 2003 526 534
5. S.D. Grabus, B.R. Martin, A.M. Batman, R.F. Tyndale, E. Sellers, and M.I. Damaj Nicotine physical dependence and tolerance in the mouse following chronic oral administration Psychopharmacology (Berl.) 178 2005 183 192
6. K.J. Jackson, B.R. Martin, J.P. Changeux, and M.I. Damaj Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs J. Pharmacol. Exp. Ther. 325 2008 302 312
7. R. Salas, A. Main, D. Gangitano, and M. De Biasi Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit Neuropharmacology 53 2007 863 869
8. C.D. Fowler, Q. Lu, P.M. Johnson, M.J. Marks, and P.J. Kenny Habenular α5 nicotinic receptor subunit signalling controls nicotine intake Nature 471 2011 597 601
9. S. Frahm, M.A. Slimak, L. Ferrarese, J. Santos-Torres, B. Antolin-Fontes, S. Auer, S. Filkin, S. Pons, J.F. Fontaine, and V. Tsetlin Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula Neuron 70 2011 522 535
10. R. Salas, R. Sturm, J. Boulter, and M. De Biasi Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice J. Neurosci. 29 2009 3014 3018
11. R. Salas, F. Pieri, and M. De Biasi Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit J. Neurosci. 24 2004 10035 10039
12. A.J. Cole, D.W. Saffen, J.M. Baraban, and P.F. Worley Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation Nature 340 1989 474 476
13. M.D. Kawaja, B.A. Flumerfelt, and A.W. Hrycyshyn Glutamate decarboxylase immunoreactivity in the rat interpeduncular nucleus: a light and electron microscope investigation Neuroscience 30 1989 741 753
14. L. Fenno, O. Yizhar, and K. Deisseroth The development and application of optogenetics Annu. Rev. Neurosci. 34 2011 389 412
15. H. Taniguchi, M. He, P. Wu, S. Kim, R. Paik, K. Sugino, D. Kvitsiani, Y. Fu, J. Lu, and Y. Lin A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex Neuron 71 2011 995 1013
16. K.R. Tan, C. Yvon, M. Turiault, J.J. Mirzabekov, J. Doehner, G. Labouèbe, K. Deisseroth, K.M. Tye, and C. Lüscher GABA neurons of the VTA drive conditioned place aversion Neuron 73 2012 1173 1183
17. H.C. Tsai, F. Zhang, A. Adamantidis, G.D. Stuber, A. Bonci, L. de Lecea, and K. Deisseroth Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning Science 324 2009 1080 1084
18. K.M. Tye, J.J. Mirzabekov, M.R. Warden, E.A. Ferenczi, H.C. Tsai, J. Finkelstein, S.Y. Kim, A. Adhikari, K.R. Thompson, and A.S. Andalman Dopamine neurons modulate neural encoding and expression of depression-related behaviour Nature 493 2013 537 541
19. H.E. Covington 3rd, M.K. Lobo, I. Maze, V. Vialou, J.M. Hyman, S. Zaman, Q. LaPlant, E. Mouzon, S. Ghose, and C.A. Tamminga Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex J. Neurosci. 30 2010 16082 16090
20. â̂ - nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption J. Neurosci. 30 2010 10169 10176
21. J. Ren, C. Qin, F. Hu, J. Tan, L. Qiu, S. Zhao, G. Feng, and M. Luo Habenula "cholinergic" neurons co-release glutamate and acetylcholine and activate postsynaptic neurons via distinct transmission modes Neuron 69 2011 445 452
22. L.M. Hemmendinger, and R.Y. Moore Interpeduncular nucleus organization in the rat: cytoarchitecture and histochemical analysis Brain Res. Bull. 13 1984 163 179
23. S. Boehm, and H. Betz Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors J. Neurosci. 17 1997 4066 4075
24. N. Zaveri, F. Jiang, C. Olsen, W. Polgar, and L. Toll Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation J. Med. Chem. 53 2010 8187 8191
25. O. Hikosaka The habenula: from stress evasion to value-based decision-making Nat. Rev. Neurosci. 11 2010 503 513
26. â̂ - subtypes mediate acetylcholine release J. Neurosci. 29 2009 2272 2282
27. A.K. Stoker, B. Olivier, and A. Markou Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice Behav. Genet. 42 2012 423 436
28. S.S. Watkins, L. Stinus, G.F. Koob, and A. Markou Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects J. Pharmacol. Exp. Ther. 292 2000 1053 1064
29. A. Plaza-Zabala, A. Flores, R. Maldonado, and F. Berrendero Hypocretin/orexin signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal Biol. Psychiatry 71 2012 214 223
30. A. Albanese, M. Castagna, and M.C. Altavista Cholinergic and non-cholinergic forebrain projections to the interpeduncular nucleus Brain Res. 329 1985 334 339
31. A. Contestabile, and B.A. Flumerfelt Afferent connections of the interpeduncular nucleus and the topographic organization of the habenulo-interpeduncular pathway: an HRP study in the rat J. Comp. Neurol. 196 1981 253 270
32. G.S. Hamill, and D.M. Jacobowitz A study of afferent projections to the rat interpeduncular nucleus Brain Res. Bull. 13 1984 527 539
33. National Research Council Guide for the Care and Use of Laboratory Animals 1996 National Academy Press Washington