메뉴 건너뛰기




Volumn 20, Issue 38, 2013, Pages 4836-4843

Module-activity relationship of G-quadruplex based DNA aptamers for human thrombin

Author keywords

Anticoagulant; DNA aptamer; Hemostasis; Inhibitor; Modular structure; Thrombin

Indexed keywords

GUANINE QUADRUPLEX; PROTHROMBIN; RECOMBINANT THROMBIN; ANTICOAGULANT AGENT; APTAMER; FIBRINOGEN; RECOMBINANT PROTEIN; THROMBIN;

EID: 84889579542     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113206660283     Document Type: Article
Times cited : (25)

References (21)
  • 1
    • 57649140709 scopus 로고    scopus 로고
    • Novel therapeutic modalities to address nondrugable protein interaction targets
    • De Souza, E.B.; Cload, S.T.; Pendergrast, P.S.; Sah, D.W.Y. Novel therapeutic modalities to address nondrugable protein interaction targets. Neuropsychopharmacology, 2009, 34, 142-158.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 142-158
    • De Souza, E.B.1    Cload, S.T.2    Pendergrast, P.S.3    Sah, D.W.Y.4
  • 2
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock, L.C.; Griffin, L.C.; Latham, J.A.; Vermaas, E.H.; Toole, J.J. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature, 1992, 355, 564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 6
    • 84870535712 scopus 로고    scopus 로고
    • High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity
    • Krauss, I.R.; Merlino, A.; Randazzo, A; Novellino, E.; Mazzarella, L.; Sica, F. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 2012, 40, 8119-8128.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 8119-8128
    • Krauss, I.R.1    Merlino, A.2    Randazzo, A.3    Novellino, E.4    Mazzarella, L.5    Sica, F.6
  • 8
    • 0029017360 scopus 로고
    • Functional mapping of the surface residues of human thrombin
    • Tsiang, M.; Jain, A.K.; Dunn, K.E.; Rojas, M.E.; Leung, L.L.K. Functional mapping of the surface residues of human thrombin. J. Biol. Chem., 1995, 270(28), 16854-16863.
    • (1995) J. Biol. Chem. , vol.270 , Issue.28 , pp. 16854-16863
    • Tsiang, M.1    Jain, A.K.2    Dunn, K.E.3    Rojas, M.E.4    Leung, L.L.K.5
  • 9
    • 0027163099 scopus 로고
    • In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits
    • Griffin, L.C.; Tidmarsh, G.F.; Bock, L.C.; Toole, J.J.; Leung, L.L.K. In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits. Blood, 1993, 81, 3271-3276. (Pubitemid 23172909)
    • (1993) Blood , vol.81 , Issue.12 , pp. 3271-3276
    • Griffin, L.C.1    Tidmarsh, G.F.2    Bock, L.C.3    Toole, J.J.4    Leung, L.L.K.5
  • 10
    • 38349044104 scopus 로고    scopus 로고
    • Stability and binding properties of a modified thrombin binding aptamer
    • Pagano, B.; Martino, L.; Randazzo, A.; Giancola, A. Stability and binding properties of a modified thrombin binding aptamer. Biophys. J., 2008, 94(2), 562-569.
    • (2008) Biophys. J. , vol.94 , Issue.2 , pp. 562-569
    • Pagano, B.1    Martino, L.2    Randazzo, A.3    Giancola, A.4
  • 11
    • 26444478237 scopus 로고    scopus 로고
    • A novel method of screening thrombin-inhibiting DNA aptamers using an evolution-mimicking algorithm
    • Ikebukuro, K.; Okumura, Y.; Sumikura, K.; Karube, I. A novel method of screening thrombin-inhibiting DNA aptamers using an evolution-mimicking algorithm. Nucleic Acids Res., 2005, 33(12), e108.
    • (2005) Nucleic Acids Res. , vol.33 , Issue.12
    • Ikebukuro, K.1    Okumura, Y.2    Sumikura, K.3    Karube, I.4
  • 14
    • 84865630601 scopus 로고    scopus 로고
    • Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer
    • Dolinnaya, N.G.; Yuminova, A.V.; Spiridonova, V.A.; Arutyunyan, A.M.; Kopylov, A. M. Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer. J. Biomol. Struct. Dyn., 2012, 30, 524- 531.
    • (2012) J. Biomol. Struct. Dyn. , vol.30 , pp. 524-531
    • Dolinnaya, N.G.1    Yuminova, A.V.2    Spiridonova, V.A.3    Arutyunyan, A.M.4    Kopylov, A.M.5
  • 15
    • 80052228547 scopus 로고    scopus 로고
    • Nucleic acid aptamers: Clinical applications and promising new horizons
    • Ni, X.; Castanares, M.; Mukherjee, A.; Lupold, S. E. Nucleic acid aptamers: clinical applications and promising new horizons. Curr. Med. Chem., 2011, 18, 4206-4214.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 4206-4214
    • Ni, X.1    Castanares, M.2    Mukherjee, A.3    Lupold, S.E.4
  • 16
    • 84855898225 scopus 로고    scopus 로고
    • Kinetic characterization of inhibition of human thrombin with DNA aptamers by turbidimetric assay
    • Zavyalova, E.G.; Protopopova, A.D., Yaminsky, I.V.; Kopylov, A.M. Kinetic characterization of inhibition of human thrombin with DNA aptamers by turbidimetric assay. Anal. Biochem., 2012, 421, 234-239.
    • (2012) Anal. Biochem. , vol.421 , pp. 234-239
    • Zavyalova, E.G.1    Protopopova, A.D.2    Yaminsky, I.V.3    Kopylov, A.M.4
  • 17
    • 33845988051 scopus 로고    scopus 로고
    • HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase
    • DOI 10.1074/jbc.M607359200
    • Kretz, C.A.; Stafford, A.R.; Fredenburgh, J.C.; Weitz, J.I. HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase. J. Biol. Chem., 2006, 281, 37477-37485. (Pubitemid 46042051)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.49 , pp. 37477-37485
    • Kretz, C.A.1    Stafford, A.R.2    Fredenburgh, J.C.3    Weitz, J.I.4
  • 18
    • 0031563773 scopus 로고    scopus 로고
    • Oligonucleotide inhibitors of human thrombin that bind distinct epitopes
    • DOI 10.1006/jmbi.1997.1275
    • Tasset, D.M.; Kubik, M.F.; Steiner, W. Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. J. Mol. Biol., 1997, 272, 688-698. (Pubitemid 27448187)
    • (1997) Journal of Molecular Biology , vol.272 , Issue.5 , pp. 688-698
    • Tasset, D.M.1    Kubik, M.F.2    Steiner, W.3
  • 19
    • 84865711340 scopus 로고    scopus 로고
    • Interaction of water with the Gquadruplex loop contributes to the binding energy of G-quadruplex to protein
    • Nagatoishia, S.; Sugimoto, N. Interaction of water with the Gquadruplex loop contributes to the binding energy of G-quadruplex to protein. Mol. BioSyst., 2012, 8, 2766-2770.
    • (2012) Mol. BioSyst. , vol.8 , pp. 2766-2770
    • Nagatoishia, S.1    Sugimoto, N.2
  • 20
    • 84870420969 scopus 로고    scopus 로고
    • DNA aptamers for human thrombin with high anticoagulant activity demonstrate target- and species-specificity
    • Zavyalova, E.; Golovin, A; Timoshenko, T; Babiy, A; Pavlova, G; Kopylov A. DNA aptamers for human thrombin with high anticoagulant activity demonstrate target- and species-specificity. Curr. Med. Chem., 2012, 19(30), 5232-5237.
    • (2012) Curr. Med. Chem. , vol.19 , Issue.30 , pp. 5232-5237
    • Zavyalova, E.1    Golovin, A.2    Timoshenko, T.3    Babiy, A.4    Pavlova, G.5    Kopylov, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.