Association of basal forebrain volumes and cognition in normal aging

Neuropsychologia

Volumn 53, Issue 1, 2014, Pages 54-63

  Wolf, D ^a   Grothe, M ^b   Fischer, F U ^a   Heinsen, H ^d   Kilimann, I ^b,c   Teipel, S ^b,c   Fellgiebel, A ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Basal forebrain cholinergic system; Brain resilience; Cognition; General intelligence; Normal aging; Nucleus basalis of Meynert

Indexed keywords

ACETYLCHOLINE;

AGE DISTRIBUTION; AGED; AGING; APTITUDE TEST; ARTICLE; BRAIN FUNCTION; BRAIN REGION; BRAIN SIZE; CHOLINERGIC SYSTEM; COGNITION; COGNITIVE DEFECT; COHORT ANALYSIS; FEMALE; FOREBRAIN; FRONTAL CORTEX; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; INTELLIGENCE; MALE; MEYNERT BASAL NUCLEUS; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEUS SUBPUTAMINALIS; PARIETAL CORTEX; PATHOPHYSIOLOGY; TEMPORAL CORTEX; VERY ELDERLY; WHITE MATTER;

BASAL FOREBRAIN CHOLINERGIC SYSTEM; BRAIN RESILIENCE; COGNITION; GENERAL INTELLIGENCE; NORMAL AGING; NUCLEUS BASALIS OF MEYNERT;

AGED; AGED, 80 AND OVER; AGING; ATTENTION; COGNITION; COHORT STUDIES; EDUCATIONAL STATUS; EXECUTIVE FUNCTION; FEMALE; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; ORGAN SIZE; TELENCEPHALON;

EID: 84889576311     PISSN: 00283932     EISSN: 18733514     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2013.11.002     Document Type: Article

References (61)

1. Arendt T., Bigl V., Tennstedt A., Arendt A. Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience 1985, 14(1):1-14.
2. Ashburner J. A fast diffeomorphic image registration algorithm. NeuroImage 2007, 38:95-113.
3. Ashburner J. A fast diffeomorphic image registration algorithm. NeuroImage 2007, 38(1):95-113.
4. Ashburner J., Friston K.J. Nonlinear spatial normalization using basis functions. Human Brain Mapping 1999, 7(4):254-266.
5. Ashburner J., Friston K.J. Unified segmentation. NeuroImage 2005, 26(3):839-851.
6. Ayala G. A hitherto undifferentiated nucleus in the forebrain (nucleus subputaminalis). Brain 1915, 37(3-4):433-448.
7. Bartus R.T. On neurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Experimental Neurology 2000, 163(2):495-529.
8. Baskin D.S., Browning J.L., Pirozzolo F.J., Korporaal S., Baskin J.A., Appel S.H. Brain choline acetyltransferase and mental function in Alzheimer disease. Archives of Neurology 1999, 56(9):1121-1123.
9. Baxter M.G., Bucci D.J., Gorman L.K., Wiley R.G., Gallagher M. Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats. Behavioral Neuroscience 1995, 109(4):714-722.
10. Birks J. Cholinesterase inhibitors for Alzheimer's disease (Review). Cochrane Database of Systematic Reviews 2012, 5. (CD005593).
11. Butler T., Blackmon K., Zaborszky L., Wang X., DuBois J., Carlson C., Kuzniecky R. Volume of the human septal forebrain region is a predictor of source memory accuracy. Journal of the International Neuropsychological Society 2011, 18(1):157-161.
12. Deary I.J., Penke L., Johnson W. The neuroscience of human intelligence differences. Nature Reviews Neuroscience 2010, 11(3):201-211.
13. Drachman D.A., Glosser G., Fleming P., Longenecker G. Memory decline in the aged treatment with lecithin and physostigmine. Neurology 1982, 32(9):944.
14. Dumas J.A., Newhouse P.A. The cholinergic hypothesis of cognitive aging revisited again: Cholinergic functional compensation. Pharmacology Biochemistry and Behavior 2011, 99(2):254-261.
15. Gao F.Q., Pettersen J.A., Bocti C., Nestor S.M., Kiss A., Black S.E. Is encroachment of the carotid termination into the substantia innominata associated with its atrophy and cognition in Alzheimer's disease?. Neurobiology of Aging 2013, 34:1807-1814.
16. Gläscher J., Rudrauf D., Colom R., Paul L., Tranel D., Damasio H., Adolphs R. Distributed neural system for general intelligence revealed by lesion mapping. Proceedings of the National Academy of Sciences 2010, 107(10):4705-4709.
17. Grothe M., Heinsen H., Teipel S.J. Atrophy of the cholinergic basal forebrain over the adult age range and in early stages of Alzheimer's disease. Biological Psychiatry 2012, 71(9):805-813.
18. Grothe M., Heinsen H., Teipel S.J. Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease. Neurobiology of Aging 2012, 34:1210-1220.
19. Grothe M., Zaborszky L., Atienza M., Gil-Neciga E., Rodriguez-Romero R., Teipel S.J., Cantero J.L. Reduction of basal forebrain cholinergic system parallels cognitive impairment in patients at high risk of developing Alzheimer's disease. Cerebral Cortex 2010, 20(7):1685-1695.
20. Grubbs F.E. Sample criteria for testing outlying observations. The Annals of Mathematical Statistics 1950, 21(1):27-58.
21. Hanyu H., Asano T., Sakurai H., Tanaka Y., Takasaki M., Abe K. MR analysis of the substantia innominata in normal aging, Alzheimer disease, and other types of dementia. American Journal of Neuroradiology 2002, 23(1):27-32.
22. Helmstaedter, C., Lendt, M., & Lux, S. (2001). VLMT: Verbaler Lern-und Merkfähigkeitstest: Beltz Test, Göttingen, Germany.
23. Hiller, W., Zaudig, M., & Mombour, W. (1997). Internationale Diagnosen-Checklisten (IDCL) für DSM-IV: Hogrefe-Verlag für Psychologie, Göttingen, Germany.
24. Horn, W. (1962). Achievement Measure System (Leistungs-Pruef-System/LPS). Hogrefe, Goettingen, Germany.
25. Kim H.-J., Moon W.-J., Han S.-H. Differential cholinergic pathway involvement in Alzheimer's disease and subcortical ischemic vascular dementia. Journal of Alzheimer's Disease 2013, 35:129-136.
26. Lowes-Hummel P., Gertz H.J., Ferszt R., Cervos-Navarro J. The basal nucleus of Meynert revised: The nerve cell number decreases with age. Archives of Gerontology and Geriatrics 1989, 8:21-27.
27. Mann D.M.A., Yates P.O., Marcyniuk B. Changes in nerve cells of the nucleus basalis of Meynert in Alzheimer's disease and their relationship to ageing and to the accumulation of lipofuscin pigment. Mechanisms of Ageing and Development 1984, 25:189-204.
28. McGeer P., McGeer E., Suzuki J., Dolman C., Nagai T. Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain. Neurology 1984, 34(6):741.
29. Mesulam M. The systems-level organization of cholinergic innervation in the human cerebral cortex and its alterations in Alzheimer's disease. Progress in Brain Research 1996, 109:285-297.
30. Mesulam M., Mufson E., Wainer B., Levey A. Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 1983, 10(4):1185-1201.
31. Missar C.D., Gold J.M., Goldberg T.E. WAIS-R short forms in chronic schizophrenia. Schizophrenia Research 1994, 12(3):247-250.
32. Muir J.L. Acetylcholine, aging, and Alzheimer's disease. Pharmacology, Biochemistry and Behavior 1997, 56:687-696.
33. Muth K., Schönmeyer R., Matura S., Haenschel C., Schröder J., Pantel J. Mild cognitive impairment in the elderly is associated with volume loss of the cholinergic basal forebrain region. Biological Psychiatry 2010, 67(6):588-591.
34. Pappas B.A., Bayley P.J., Bui B.K., Hansen L.A., Thal L.J. Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients< sup>{star, open}. Neurobiology of Aging 2000, 21(1):11-17.
35. Plassman B.L., Welsh K., Helms M., Brandt J., Page W., Breitner J. Intelligence and education as predictors of cognitive state in late life A 50-year follow-up. Neurology 1995, 45(8):1446-1450.
36. Raghanti M.-A., Simic G., Watson S., Stimpson C.D., Hof P.R., Sherwood C.C. Comparative analysis of the nucleus basalis of Meynert among primates. Neuroscience 2011, 184:1-15.
37. Reitan R.M. Trail making test: Manual for administration and scoring 1992, Reitan Neuropsychology Laboratory.
38. Sarter M., Bruno J.P. Developmental origins of the age-related decline in cortical cholinergic function and associated cognitive abilities. Neurobiology of Aging 2004, 25(9):1127-1139.
39. Sarter M., Bruno J.P., Givens B. Attentional functions of cortical cholinergic inputs: What does it mean for learning and memory?. Neurobiology of Learning and Memory 2003, 80(3):245-256.
40. Sassin I., Schultz C., Thal D.R., Rüb U., Arai K., Braak E., Braak H. Evolution of Alzheimer's disease-related cytoskeletal changes in the basal nucleus of Meynert. Acta Neuropathologica 2000, 100(3):259-269.
41. Schliebs R., Arendt T. The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. Journal of Neural Transmission 2006, 113(11):1625-1644.
42. Schoenbaum G., Roesch M.R., Stalnaker T.A. Orbitofrontal cortex, decision-making and drug addiction. Trends in Neurosciences 2006, 29(2):116-124.
43. Selden N.R., Gitelman D.R., Salamon-Murayama N., Parrish T.B., Mesulam M.-M. Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain. Brain 1998, 121(12):2249-2257.
44. Shallice T. Specific impairments of planning. Philosophical Transactions of the Royal Society of London. B, Biological Sciences 1982, 298(1089):199-209.
45. Simić G., Mrzljak L., Fučić A., Winblad B., Lovrić H., Kostović I. Nucleus subputaminalis (Ayala): The still disregarded magnocellular component of the basal forebrain may be human specific and connected with the cortical speech area. Neuroscience 1999, 89(1):73-89.
46. Stern Y. What is cognitive reserve? Theory and research application of the reserve concept. Journal of the International Neuropsychological Society 2002, 8(03):448-460.
47. Stern Y. Cognitive reserve and Alzheimer disease. Alzheimer Disease & Associated Disorders 2006, 20(2):112-117.
48. Tabert M.H., Manly J.J., Liu X., Pelton G.H., Rosenblum S., Jacobs M., Stern Y. Neuropsychological prediction of conversion to Alzheimer disease in patients with mild cognitive impairment. Archives of General Psychiatry 2006, 63:916-924.
49. Teipel S.J., Flatz W., Grothe M., Kilimann I., Bokde A., Grinberg L., Danek A. Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus. Psychiatry Research Neuroimaging 2013, (accepted).
50. Teipel S.J., Flatz W.H., Heinsen H., Bokde A.L., Schoenberg S.O., Stöckel S., Hampel H. Measurement of basal forebrain atrophy in Alzheimer's disease using MRI. Brain 2005, 128(11):2626-2644.
51. Teipel S.J., Meindl T., Grinberg L., Grothe M., Cantero J.L., Reiser M.F., Hampel H. The cholinergic system in mild cognitive impairment and Alzheimer's disease: An in vivo MRI and DTI study. Human Brain Mapping 2010, 32(9):1349-1362.
52. Tewes, U., & Wechsler, D. (1991). Hamburg-Wechsler-Intelligenztest für Erwachsene-Revision [Hamburg-Wechsler intelligence test for adults-revised]. Huber-Verlag, Göttingen, Germany.
53. Vogels O., Broere C., Ter Laak H., Ten Donkelaar H., Nieuwenhuys R., Schulte B. Cell loss and shrinkage in the nucleus basalis Meynert complex in Alzheimer's disease. Neurobiology of Aging 1990, 11(1):3-13.
54. Wechsler D. WMS-R: Wechsler memory scale-revised: Manual 1987, Psychological Corporation, San Antonio.
55. Wenk G.L., Stoehr J.D., Quintana G., Mobley S., Wiley R.G. Behavioral, biochemical, histological, and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats. The Journal of Neuroscience 1994, 14(10):5986-5995.
56. Whitehouse P.J., Price D.L., Clark A.W., Coyle J.T., DeLong M.R. Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis. Annals of Neurology 1981, 10(2):122-126.
57. Wittchen H., Pfister H. DIA-X interview 1997, Swets Test Services, Frankfurt, Germany.
58. Wrenn C.C., Lappi D.A., Wiley R.G. Threshold relationship between lesion extent of the cholinergic basal forebrain in the rat and working memory impairment in the radial maze. Brain Research 1999, 847(2):284-298.
59. Yeo R.A., Arden R., Jung R.E. Alzheimer's disease and intelligence. [Review]. urrent Alzheimer Research 2011, 8(4):345-353.
60. Zaborszky L., Hoemke L., Mohlberg H., Schleicher A., Amunts K., Zilles K. Stereotaxic probabilistic maps of the magnocellular cell groups in human basal forebrain. NeuroImage 2008, 42(3):1127-1141.
61. Zimmermann, P., & Fimm, B. (1995). Test battery for attention performance (TAP). Psytest, Wuerselen, Germany.