Advancing critical care medicine with stem cell therapy and hypothermia for cerebral palsy

NeuroReport

Volumn 24, Issue 18, 2013, Pages 1067-1071

  Dailey, Travis ^a   Mosley, Yusef ^a   Pabon, Mibel ^a   Acosta, Sandra ^a   Tajiri, Naoki ^a   Van Loveren, Harry ^a   Kaneko, Yuji ^a   Borlongan, Cesar V ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Cell transplantation; Clinical applications; Neonatal hypoxic ischemic injury; Translational research

Indexed keywords

DELTA OPIATE RECEPTOR AGONIST;

ARTICLE; CELL THERAPY; CEREBRAL PALSY; CEREBROVASCULAR ACCIDENT; HUMAN; HYPOTHERMIA; HYPOXIA; INTENSIVE CARE; PATIENT SAFETY; PRACTICE GUIDELINE; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; TRANSLATIONAL RESEARCH; TREATMENT OUTCOME;

CEREBRAL PALSY; COMBINED MODALITY THERAPY; CRITICAL CARE; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; STEM CELL TRANSPLANTATION; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84889254590     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000062     Document Type: Article

References (50)

1. Arneson CL, Durkin MS, Benedict RE, Kirby RS, Yeargin-Allsopp M, Van Naarden Braun K, et al. Prevalence of cerebral palsy: Autism and Developmental Disabilities Monitoring Network, three sites, United States, 2004. Disabil Health J 2009; 2:45-48.
2. Bjorkman ST, Miller SM, Rose SE, Burke C, Colditz PB. Seizures are associated with brain injury severity in a neonatal model of hypoxia-ischemia. Neuroscience 2010; 166:157-167.
3. MacDonald HM, Mulligan JC, Allen AC, Taylor PM. Neonatal asphyxia. I. Relationship of obstetric and neonatal complications to neonatal mortality in 38,405 consecutive deliveries. J Pediatr 1980; 96:898-902. (Pubitemid 10068229)
4. Finer NN, Robertson CM, Richards RT, Pinnell LE, Peters KL. Hypoxicischemic encephalopathy in term neonates: perinatal factors and outcome. J Pediatr 1981; 98:112-117. (Pubitemid 11184076)
5. Raju TN. Ischemic perinatal stroke: challenge and opportunities. Int J Stroke 2008; 3:169-172.
6. Johnston MV, Fatemi A, Wilson MA, Northington F. Treatment advances in neonatal neuroprotection and neurointensive care. Lancet Neurol 2011; 10:372-382.
7. Gluckman PD, Wyatt JS, Azzopardi D, Ballard R, Edwards AD, Ferriero DM, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 2005; 365:663-670. (Pubitemid 40260887)
8. Shankaran S, Laptook AR, Ehrenkranz RA, Tyson JE, McDonald SA, Donovan EF, et al. Whole-body hypothermia for neonates with hypoxicischemic encephalopathy. N Engl J Med 2005; 353:1574-1584. (Pubitemid 41434636)
9. Kondziolka D, Wechsler L, Goldstein S, Meltzer C, Thulborn KR, Gebel J, et al. Transplantation of cultured human neuronal cells for patients with stroke. Neurology 2000; 55:565-569. (Pubitemid 30647258)
10. Yu G, Fournier C, Hess DC, Borlongan CV. Transplantation of carotid body cells in the treatment of neurological disorders. Neurosci Biobehav Rev 2005; 28:803-810. (Pubitemid 40092052)
11. Borlongan CV. Cell therapy for stroke: remaining issues to address before embarking on clinical trials. Stroke 2009; 40:S146-S148.
12. Sun J, Allison J, McLaughlin C, Sledge L, Waters-Pick B, Wease S, et al. Differences in quality between privately and publicly banked umbilical cord blood units: a pilot study of autologous cord blood infusion in children with acquired neurologic disorders. Transfusion 2010; 50:1980-1987.
13. Dailey T, Tajiri N, Kaneko Y, Borlongan CV. Regeneration of neuronal cells following cerebral injury. Front Neurol Neurosci 2013; 32:54-61.
14. Hess DC, Borlongan CV. Stem cells and neurological diseases. Cell Prolif 2008; 41 (Suppl 1):94-114. (Pubitemid 350295855)
15. Stroke Therapy Academic Industry Roundtable (STAIR). Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 1999; 30:2752-2758.
16. Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, et al. Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke 2009; 40:2244-2250.
17. Chopp M, Steinberg GK, Kondziolka D, Lu M, Bliss TM, Li Y, et al. Who's in favor of translational cell therapy for stroke: STEPS forward please? Cell Transplant 2009; 18:691-693.
18. Borlongan CV, Chopp M, Steinberg GK, Bliss TM, Li Y, Lu M, et al. Potential of stem/progenitor cells in treating stroke: the missing steps in translating cell therapy from laboratory to clinic. Regen Med 2008; 3:249-250.
19. Stem Cell Therapies as an Emerging Paradigm in Stroke Participants. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke 2009; 40:510-515.
20. Borlongan CV, Weiss MD. Baby STEPS: a giant leap for cell therapy in neonatal brain injury. Pediatr Res 2011; 70:3-9.
21. Robertson CM, Finer NN. Long-term follow-up of term neonates with perinatal asphyxia. Clin Perinatol 1993; 20:483-500.
22. Yasuhara T, Hara K, Maki M, Mays RW, Deans RJ, Hess DC, et al. Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats. J Cereb Blood Flow Metab 2008; 28:1804-1810.
23. Hobbs C, Thoresen M, Tucker A, Aquilina K, Chakkarapani E, Dingley J. Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia. Stroke 2008; 39:1307-1313. (Pubitemid 351440706)
24. Carroll JE, Borlongan CV. Adult stem cell therapy for acute brain injury in children. CNS Neurol Disord Drug Targets 2008; 7:361-369.
25. Kim CT, Han J, Kim H. Pediatric stroke recovery: a descriptive analysis. Arch Phys Med Rehabil 2009; 90:657-662.
26. Liao Y, Cotten M, Tan S, Kurtzberg J, Cairo MS. Rescuing the neonatal brain from hypoxic injury with autologous cord blood. Bone Marrow Transplant 2013; 48:890-900.
27. Battin MR, Dezoete JA, Gunn TR, Gluckman PD, Gunn AJ. Neurodevelopmental outcome of infants treated with head cooling and mild hypothermia after perinatal asphyxia. Pediatrics 2001; 107:480-484. (Pubitemid 32183180)
28. Battin MR, Penrice J, Gunn TR, Gunn AJ. Treatment of term infants with head cooling and mild systemic hypothermia (35.0 degrees C and 34.5 degrees C) after perinatal asphyxia. Pediatrics 2003; 111:244-251. (Pubitemid 36177139)
29. Lei B, Tan X, Cai H, Xu Q, Guo Q. Effect of moderate hypothermia on lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation. Stroke 1994; 25:147-152.
30. Deng W, Aimone JB, Gage FH. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 2010; 11:339-350.
31. Yenari M, Kitagawa K, Lyden P, Perez-Pinzon M. Metabolic downregulation: a key to successful neuroprotection? Stroke 2008; 39:2910-2917.
32. Iadecola C, Anrather J. Stroke research at a crossroad: asking the brain for directions. Nat Neurosci 2011; 14:1363-1368.
33. Gunn AJ, Gunn TR. The 'pharmacology' of neuronal rescue with cerebral hypothermia. Early Hum Dev 1998; 53:19-35. (Pubitemid 28479742)
34. Azzopardi DV, Strohm B, Edwards AD, Dyet L, Halliday HL, Juszczak E, et al. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med 2009; 361:1349-1358.
35. Tagin MA, Woolcott CG, Vincer MJ, Whyte RK, Stinson DA. Hypothermia for neonatal hypoxic ischemic encephalopathy: an updated systematic review and meta-analysis. Arch Pediatr Adolesc Med 2012; 166:558-566.
36. Shankaran S, Laptook A, Wright LL, Ehrenkranz RA, Donovan EF, Fanaroff AA, et al. Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants. Pediatrics 2002; 110:377-385. (Pubitemid 34833026)
37. Wu YW, Bauer LA, Ballard RA, Ferriero DM, Glidden DV, Mayock DE, et al. Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics 2012; 130:683-691.
38. Dickinson R, Franks NP. Bench-to-bedside review: molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection. Crit Care 2010; 14:229.
39. Borlongan CV, Glover LE, Tajiri N, Kaneko Y, Freeman TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Prog Neurobiol 2011; 95:213-228.
40. Borlongan CV, Kaneko Y, Maki M, Yu SJ, Ali M, Allickson JG, et al. Menstrual blood cells display stem cell-like phenotypic markers and exert neuroprotection following transplantation in experimental stroke. Stem Cells Dev 2010; 19:439-452.
41. Robertson NJ, Nakakeeto M, Hagmann C, Cowan FM, Acolet D, Iwata O, et al. Therapeutic hypothermia for birth asphyxia in low-resource settings: a pilot randomised controlled trial. Lancet 2008; 372:801-803.
42. Borlongan CV, Lind JG, Dillon-Carter O, Yu G, Hadman M, Cheng C, et al. Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res 2004; 1010:108-116. (Pubitemid 38569858)
43. Boutin H, Dauphin F, MacKenzie ET, Jauzac P. Differential time-course decreases in nonselective, mu-, delta-, and kappa-opioid receptors after focal cerebral ischemia in mice. Stroke 1999; 30:1271-1277, discussion 1278. (Pubitemid 29259185)
44. Tsai SY, Lee CT, Hayashi T, Freed WJ, Su TP. Delta opioid peptide DADLE and naltrexone cause cell cycle arrest and differentiation in a CNS neural progenitor cell line. Synapse 2010; 64:267-273.
45. Borlongan CV, Su TP, Wang Y. Treatment with delta opioid peptide enhances in vitro and in vivo survival of rat dopaminergic neurons. Neuroreport 2000; 11:923-926. (Pubitemid 30235429)
46. Kaneko Y, Tajiri N, Su TP, Wang Y, Borlongan CV. Combination treatment of hypothermia and mesenchymal stromal cells amplifies neuroprotection in primary rat neurons exposed to hypoxic-ischemic-like injury in vitro: role of the opioid system. PloS One 2012; 7:e47583.
47. Ferriero DM. Neonatal brain injury. N Engl J Med 2004; 351:1985-1995.
48. Jensen A, Hamelmann E. First autologous cell therapy of cerebral palsy caused by hypoxic-ischemic brain damage in a child after cardiac arrest-individual treatment with cord blood. Case Rep Transplant 2013; 2013:951827.
49. Grunwald IQ, Walter S, Shamdeen MG, Dautermann A, Roth C, Haass A, et al. New mechanical recanalization devices - the future in pediatric stroke treatment? J Invasive Cardiol 2010; 22:63-66.
50. Ganesan V. Pediatric stroke guidelines: Where will these take future research and treatment options for childhood stroke? Expert Rev Neurother 2009; 9:639-648.