1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes

Molecular Nutrition and Food Research

Volumn 57, Issue 12, 2013, Pages 2137-2146

  Salles, Jérôme ^a,b   Chanet, Audrey ^a,b   Giraudet, Christophe ^a,b   Patrac, Véronique ^a,b   Pierre, Philippe ^c,d,e   Jourdan, Marion ^f   Luiking, Yvette C ^f   Verlaan, Sjors ^f   Migné, Carole ^a,b   Boirie, Yves ^a,b,g   Walrand, Stéphane ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b CRNH AUVERGNE   (France)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d INSERM   (France)

^e CNRS   (France)

^f Nutricia Nederland   (Netherlands)

^g UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

Author keywords

1,25(OH)2 vitamin D3; Akt mTOR pathway; C2C12 myotubes; Protein synthesis rate; Skeletal muscle

Indexed keywords

ANABOLIC AGENT; CALCITRIOL; CALCITRIOL RECEPTOR; INSULIN; INSULIN RECEPTOR; LEUCINE; MTOR PROTEIN, MOUSE; PROTEIN KINASE B; TARGET OF RAPAMYCIN KINASE;

1,25(OH)2-VITAMIN D3; AKT/MTOR PATHWAY; ANIMAL; ARTICLE; C2C12 MYOTUBES; DRUG EFFECT; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS RATE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

1,25(OH)2-VITAMIN D3; AKT/MTOR PATHWAY; C2C12 MYOTUBES; PROTEIN SYNTHESIS RATE; SKELETAL MUSCLE;

ANABOLIC AGENTS; ANIMALS; CALCITRIOL; INSULIN; LEUCINE; MICE; MUSCLE FIBERS, SKELETAL; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; RECEPTORS, CALCITRIOL; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84889030273     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201300074     Document Type: Article

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