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Volumn 3, Issue , 2013, Pages

Common pharmacophore of structurally distinct small-molecule inhibitors of intracellular retrograde trafficking of ribosome inactivating proteins

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR LIBRARY; RIBOSOME INACTIVATING PROTEIN; RICIN;

EID: 84889029045     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep03397     Document Type: Article
Times cited : (9)

References (29)
  • 1
    • 27744564219 scopus 로고    scopus 로고
    • Ricin poisoning: A comprehensive review
    • Audi, J., Belson, M., Patel, M., Schier, J. & Osterloh, J. Ricin poisoning: a comprehensive review. JAMA 294, 2342-2351 (2005).
    • (2005) JAMA , vol.294 , pp. 2342-2351
    • Audi, J.1    Belson, M.2    Patel, M.3    Schier, J.4    Osterloh, J.5
  • 2
    • 80052752526 scopus 로고    scopus 로고
    • Shiga toxin type 2 (Stx2), a potential agent of bioterrorism, has a short distribution and a long elimination half-life, and induces kidney and thymus lesions in rats
    • Liu, Y.-N. et al. Shiga toxin type 2 (Stx2), a potential agent of bioterrorism, has a short distribution and a long elimination half-life, and induces kidney and thymus lesions in rats. Arch. Toxicol. 85, 1133-1140 (2011).
    • (2011) Arch. Toxicol. , vol.85 , pp. 1133-1140
    • Liu, Y.-N.1
  • 3
    • 80955168000 scopus 로고    scopus 로고
    • Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany
    • Frank, C. et al. Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany. N. Engl. J. Med. 365, 1771-1780 (2011).
    • (2011) N. Ngl. J. Med. , vol.365 , pp. 1771-1780
    • Frank, C.1
  • 4
    • 75749125021 scopus 로고    scopus 로고
    • Shiga toxins-from cell biology to biomedical applications
    • Johannes, L. & Römer, W. Shiga toxins-from cell biology to biomedical applications. Nat. Rev. Microbiol. 8, 105-116 (2010).
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 105-116
    • Johannes, L.1    Römer, W.2
  • 5
    • 79953065234 scopus 로고    scopus 로고
    • Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach
    • Pang, Y.-P. et al. Small-molecule inhibitor leads of ribosome- inactivating proteins developed using the doorstop approach. PLoS One 6, e17883 (2011).
    • (2011) PLoS One , vol.6
    • Pang, Y.-P.1
  • 6
    • 77951735286 scopus 로고    scopus 로고
    • Inhibition of retrograde transport protects mice from lethal ricin challenge
    • Stechmann, B. et al. Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell 141, 231-242 (2010).
    • (2010) Cell , vol.141 , pp. 231-242
    • Stechmann, B.1
  • 7
    • 84866128052 scopus 로고    scopus 로고
    • Chemical structure of Retro-2, a compound that protects cells against ribosome-inactivating proteins
    • Park, J. G., Kahn, J.N., Tumer, N. E.& Pang, Y. P. Chemical structure of Retro-2, a compound that protects cells against ribosome-inactivating proteins. Sci. Rep. 2, 631 (2012).
    • (2012) Sci. Rep. , vol.2 , pp. 631
    • Park, J.G.1    Kahn, J.N.2    Tumer, N.E.3    Pang, Y.P.4
  • 8
    • 49449111557 scopus 로고    scopus 로고
    • Asymmetric synthesis of 2,3-dihydro-2-arylquinazolin-4-ones: Methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity
    • Chinigo, G. M. et al. Asymmetric synthesis of 2,3-dihydro-2- arylquinazolin-4-ones: methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity. J. Med. Chem. 51, 4620-4631 (2008).
    • (2008) J. Med. Chem. , vol.51 , pp. 4620-4631
    • Chinigo, G.M.1
  • 9
    • 56749163583 scopus 로고    scopus 로고
    • Direct catalytic asymmetric synthesis of cyclic aminals from aldehydes
    • Cheng, X., Vellalath, S., Goddard, R. & List, B. Direct catalytic asymmetric synthesis of cyclic aminals from aldehydes. J. Am. Chem. Soc. 130, 15786-15787 (2008).
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 15786-15787
    • Cheng, X.1    Vellalath, S.2    Goddard, R.3    List, B.4
  • 10
    • 58349118504 scopus 로고    scopus 로고
    • Asymmetric Brønsted acid catalysis: Catalytic enantioselective synthesis of highly biologically active dihydroquinazolinones
    • Rueping, M., Antonchick, A. P., Sugiono, E.& Grenader, K. Asymmetric Brønsted acid catalysis: catalytic enantioselective synthesis of highly biologically active dihydroquinazolinones. Angew. Chem. Int. Ed. 48, 908-910 (2009).
    • (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 908-910
    • Rueping, M.1    Antonchick, A.P.2    Sugiono, E.3    Grenader, K.4
  • 11
    • 84859566907 scopus 로고    scopus 로고
    • Highly enantioselective synthesis of 2,3-dihydroquinazolinones through intramolecular amidation of imines
    • Prakash, M. & Kesavan, V. Highly enantioselective synthesis of 2,3-dihydroquinazolinones through intramolecular amidation of imines. Org. Lett. 14, 1896-1899 (2012).
    • (2012) Org. Lett. , vol.14 , pp. 1896-1899
    • Prakash, M.1    Kesavan, V.2
  • 12
    • 84859952313 scopus 로고    scopus 로고
    • Catalytic asymmetric synthesis of dihydroquinazolinones from imines and 2-aminobenzamides
    • Cheng, D.-J., Tian, Y. & Tian, S.-K. Catalytic asymmetric synthesis of dihydroquinazolinones from imines and 2-aminobenzamides. Adv. Synth. Catal. 354, 995-999 (2012).
    • (2012) Adv. Synth. Catal. , vol.354 , pp. 995-999
    • Cheng, D.-J.1    Tian, Y.2    Tian, S.-K.3
  • 13
    • 0034697381 scopus 로고    scopus 로고
    • Liquid chromatographic separation of the stereoisomers of thiazide diuretics
    • Hyun, M. H. & Pirkle, W. H. Liquid chromatographic separation of the stereoisomers of thiazide diuretics. J. Chromatogr. A 876, 221-227 (2000).
    • (2000) J. Chromatogr. A , vol.876 , pp. 221-227
    • Hyun, M.H.1    Pirkle, W.H.2
  • 14
    • 0028935002 scopus 로고
    • Dimethyl dichloro-and chloromethylphenylcarbamates of amylose as chiral stationary phases for highperformance liquid chromatography
    • Chankvetadze, B., Yashima, E. & Okamoto, Y. Dimethyl-, dichloro-and chloromethylphenylcarbamates of amylose as chiral stationary phases for highperformance liquid chromatography. J. Chromatogr. A 694, 101-109 (1995).
    • (1995) J. Chromatogr. A , vol.694 , pp. 101-109
    • Chankvetadze, B.1    Yashima, E.2    Okamoto, Y.3
  • 15
    • 0016751728 scopus 로고
    • Studies on organosulfur compounds XII: Syntheses and pharmacological activities of 2-heterocyclic substituted 4(3H)-quinazolinones
    • Hisano, T., Ichikawa, M., Nakagawa, A. & Tsuji, M. Studies on organosulfur compounds XII: syntheses and pharmacological activities of 2-heterocyclic substituted 4(3H)-quinazolinones. Chem. Pharm. Bull. 23, 1910-1916 (1975).
    • (1975) Chem. Pharm. Bull. , vol.23 , pp. 1910-1916
    • Hisano, T.1    Ichikawa, M.2    Nakagawa, A.3    Tsuji, M.4
  • 16
    • 8444229890 scopus 로고
    • Quinazolinone sulfonamides as diuretic agents
    • Cohen, E., Klarberg, B. & Vaughan, J. R. Quinazolinone sulfonamides as diuretic agents. J. Am. Chem. Soc. 81, 5508-5509 (1959).
    • (1959) J. Am. Chem. Soc. , vol.81 , pp. 5508-5509
    • Cohen, E.1    Klarberg, B.2    Vaughan, J.R.3
  • 17
    • 0000091591 scopus 로고
    • Substituted 2,3-dihydro-4(1H)-quinazolinones. A new class of inhibitors of cell multiplication
    • Yale, H. L. & Kalkstein, M. Substituted 2,3-dihydro-4(1H)- quinazolinones. A new class of inhibitors of cell multiplication. J. Med. Chem. 10, 334-336 (1967).
    • (1967) J. Med. Chem. , vol.10 , pp. 334-336
    • Yale, H.L.1    Kalkstein, M.2
  • 18
    • 0014349746 scopus 로고
    • L-Aminoacyl-2,3-dihydro-4(1H)-quinazolinoiie derivatives with choleretic and antifibrillatory activity
    • Bonola, G., DaRe, P., Magistretti, M. J., Massarani, E. & Setnikar, I. l-Aminoacyl-2,3-dihydro-4(1H)-quinazolinoiie derivatives with choleretic and antifibrillatory activity. J. Med. Chem. 11, 1136-1139 (1968).
    • (1968) J. Med. Chem. , vol.11 , pp. 1136-1139
    • Bonola, G.1    Dare, P.2    Magistretti, M.J.3    Massarani, E.4    Setnikar, I.5
  • 19
    • 0014263577 scopus 로고
    • Oxo-1,2,3,4-tetrahydroquinazolines. I. Syntheses and pharmacological properties of 2-methyl-3-aryl-4-oxo-1,2,3,4-tetrahydroquinazolines and their 1-acyl derivatives
    • Okumura, K., Oine, T., Yamada, Y., Hayashi, G. & Nakama, M. 4-Oxo-1,2,3,4-tetrahydroquinazolines. I. Syntheses and pharmacological properties of 2-methyl-3-aryl-4-oxo-1,2,3,4-tetrahydroquinazolines and their 1-acyl derivatives. J. Med. Chem. 11, 348-352 (1968).
    • (1968) J. Med. Chem. , vol.11 , pp. 348-352
    • Okumura, K.1    Oine, T.2    Yamada, Y.3    Hayashi, G.4    Nakama, M.5
  • 20
    • 0015308671 scopus 로고
    • Antibacterial 2,3-Dihydro-2-(5-nitro-Zthieny1)-quinazolin-4(1H)-one
    • Alaimo, R. J. & Russell, H. E. Antibacterial 2,3-Dihydro-2-(5-nitro- Zthieny1)-quinazolin-4(1H)-one. J. Med. Chem. 15, 335-336 (1972).
    • (1972) J. Med. Chem. , vol.15 , pp. 335-336
    • Alaimo, R.J.1    Russell, H.E.2
  • 21
    • 0015329105 scopus 로고
    • Antitumor effects of the antispermatogenic agent 2,3-dihydro-2-(1- naphthyl)-4(1H)-quinazolinone (NSC-145669)
    • Neil, G. L., Li, L. H., Buskirk, H. H. & Moxley, T. E. Antitumor effects of the antispermatogenic agent, 2,3-dihydro-2-(1-naphthyl)-4(1H)- quinazolinone (NSC-145669). Cancer Chemother. Rep. 56, 163-173 (1972).
    • (1972) Cancer Chemother. Rep. , Issue.56 , pp. 163-173
    • Neil, G.L.1    Li, L.H.2    Buskirk, H.H.3    Moxley, T.E.4
  • 22
    • 0028327496 scopus 로고
    • The synthesis of 2,3-dihydro-4(1H)-quinazolinone angiotensin II receptor antagonists
    • Levin, J. I., Chan, P. S., Bailey, T., Katocs, A. S. & Venkatesan, A. The synthesis of 2,3-dihydro-4(1H)-quinazolinone angiotensin II receptor antagonists. Bioorg. Med. Chem. Lett. 4, 1141-1146 (1994).
    • (1994) Bioorg. Med. Chem. Lett. , vol.4 , pp. 1141-1146
    • Levin, J.I.1    Chan, P.S.2    Bailey, T.3    Katocs, A.S.4    Venkatesan, A.5
  • 23
    • 0034676319 scopus 로고    scopus 로고
    • 6-Alkylamino-and 2,3-dihydro-39-methoxy-2-phenyl-4-quinazolinones and related compounds: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization
    • Hour, M. J. et al. 6-Alkylamino-and 2,3-dihydro-39-methoxy-2-phenyl-4- quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. J. Med. Chem. 43, 4479-4487 (2000).
    • (2000) J. Med. Chem. , vol.43 , pp. 4479-4487
    • Hour, M.J.1
  • 24
    • 84876864878 scopus 로고    scopus 로고
    • N-methyldihydroquinazolinone derivatives of Retro-2 with enhanced efficacy against Shiga toxin
    • Noel, R. et al. N-methyldihydroquinazolinone derivatives of Retro-2 with enhanced efficacy against Shiga toxin. J. Med. Chem. 56, 3404-3413 (2013).
    • (2013) J. Med. Chem. , vol.56 , pp. 3404-3413
    • Noel, R.1
  • 25
    • 34548490308 scopus 로고    scopus 로고
    • Identification and characterization of small molecules that inhibit intracellular toxin transport
    • Saenz, J. B., Doggett, T. A. & Haslam, D. B. Identification and characterization of small molecules that inhibit intracellular toxin transport. Infect. Immun. 75, 4552-4561 (2007).
    • (2007) Infect. Immun. , vol.75 , pp. 4552-4561
    • Saenz, J.B.1    Doggett, T.A.2    Haslam, D.B.3
  • 26
    • 40749129010 scopus 로고    scopus 로고
    • Preference of small molecules for local minimum conformations when binding to proteins
    • Wang, Q. & Pang, Y.-P. Preference of small molecules for local minimum conformations when binding to proteins. PLoS ONE 2, e820 (2007).
    • (2007) PLoS ONE , vol.2
    • Wang, Q.1    Pang, Y.-P.2
  • 27
    • 40749121385 scopus 로고    scopus 로고
    • Normal-mode-analysis-monitored energy minimization procedure for generating small-molecule bound conformations
    • Wang, Q. & Pang, Y.-P. Normal-mode-analysis-monitored energy minimization procedure for generating small-molecule bound conformations. PLoS ONE 2, e1025 (2007).
    • (2007) PLoS ONE , vol.2
    • Wang, Q.1    Pang, Y.-P.2
  • 29
    • 0024523894 scopus 로고
    • Pathogenesis of shigella diarrhea. XIV. Analysis of shiga toxin receptors on cloned HeLa cells
    • Jacewicz, M., Feldman, H. A., Donohue-Rolfe, A., Balasubramanian, K. A. & Keusch, G. T. Pathogenesis of Shigella diarrhea. XIV. Analysis of Shiga toxin receptors on cloned HeLa cells. J. Infect. Dis. 159, 881-889 (1989). Diseases
    • (1989) J. Infect. Dis. , vol.159 , pp. 881-889
    • Jacewicz, M.1    Feldman, H.A.2    Donohue-Rolfe, A.3    Balasubramanian, K.A.4    Keusch, G.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.