-
1
-
-
38549096018
-
MEROPS. The peptidase database
-
Rawlings, N. D., Morton, F. R., Kok, C. Y., Kong, J., and Barrett, A. J. (2008) MEROPS. The peptidase database. Nucleic Acids Res. 36, D320-D325
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Rawlings, N.D.1
Morton, F.R.2
Kok, C.Y.3
Kong, J.4
Barrett, A.J.5
-
2
-
-
67650361071
-
Serine proteases
-
Di Cera, E. (2009) Serine proteases. IUBMB Life 61, 510-515
-
(2009)
IUBMB Life
, vol.61
, pp. 510-515
-
-
Di Cera, E.1
-
3
-
-
3042615524
-
Mast cell tryptase, a still enigmatic enzyme
-
Fiorucci, L., and Ascoli, F. (2004) Mast cell tryptase, a still enigmatic enzyme. Cell. Mol. Life Sci. 61, 1278-1295
-
(2004)
Cell. Mol. Life Sci
, vol.61
, pp. 1278-1295
-
-
Fiorucci, L.1
Ascoli, F.2
-
4
-
-
71749098499
-
Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations
-
Trivedi, N. N., Tamraz, B., Chu, C., Kwok, P. Y., and Caughey, G. H. (2009) Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. J. Allergy Clin. Immunol. 124, 1099-1105
-
(2009)
J. Allergy Clin. Immunol
, vol.124
, pp. 1099-1105
-
-
Trivedi, N.N.1
Tamraz, B.2
Chu, C.3
Kwok, P.Y.4
Caughey, G.H.5
-
5
-
-
0024434198
-
Cloning and characterization of complementary DNA for human tryptase
-
Miller, J. S., Westin, E. H., and Schwartz, L. B. (1989) Cloning and characterization of complementary DNA for human tryptase. J. Clin. Invest. 84, 1188-1195
-
(1989)
J. Clin. Invest
, vol.84
, pp. 1188-1195
-
-
Miller, J.S.1
Westin, E.H.2
Schwartz, L.B.3
-
6
-
-
0025368035
-
Human mast cell tryptase. Multiple cDNAs and genes reveal a multigene serine protease family
-
Vanderslice, P., Ballinger, S. M., Tam, E. K., Goldstein, S. M., Craik, C. S., and Caughey, G. H. (1990) Human mast cell tryptase. Multiple cDNAs and genes reveal a multigene serine protease family. Proc. Natl. Acad. Sci. U.S.A. 87, 3811-3815
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 3811-3815
-
-
Vanderslice, P.1
Ballinger, S.M.2
Tam, E.K.3
Goldstein, S.M.4
Craik, C.S.5
Caughey, G.H.6
-
7
-
-
10644257614
-
Inhibitors of mast cell tryptase β as therapeutics for the treatment of asthma and inflammatory disorders
-
Cairns, J. A. (2005) Inhibitors of mast cell tryptase β as therapeutics for the treatment of asthma and inflammatory disorders. Pulm. Pharmacol. Ther. 18, 55-66
-
(2005)
Pulm. Pharmacol. Ther
, vol.18
, pp. 55-66
-
-
Cairns, J.A.1
-
8
-
-
0023779802
-
Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response
-
Castells, M., and Schwartz, L. B. (1988) Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response. J. Allergy Clin. Immunol. 82, 348-355
-
(1988)
J. Allergy Clin. Immunol
, vol.82
, pp. 348-355
-
-
Castells, M.1
Schwartz, L.B.2
-
9
-
-
0025913012
-
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction
-
Jarjour, N. N., Calhoun, W. J., Schwartz, L. B., and Busse, W. W. (1991) Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction. Am. Rev. Respir. Dis. 144, 83-87
-
(1991)
Am. Rev. Respir. Dis
, vol.144
, pp. 83-87
-
-
Jarjour, N.N.1
Calhoun, W.J.2
Schwartz, L.B.3
Busse, W.W.4
-
10
-
-
0030694130
-
Mast cell activation in arthritis. Detection of α- And β-tryptase, histamine and eosinophil cationic protein in synovial fluid
-
Buckley, M. G., Walters, C., Wong, W. M., Cawley, M. I., Ren, S., Schwartz, L. B., and Walls, A. F. (1997) Mast cell activation in arthritis. Detection of α- and β-tryptase, histamine and eosinophil cationic protein in synovial fluid. Clin. Sci. 93, 363-370
-
(1997)
Clin. Sci
, vol.93
, pp. 363-370
-
-
Buckley, M.G.1
Walters, C.2
Wong, W.M.3
Cawley, M.I.4
Ren, S.5
Schwartz, L.B.6
Walls, A.F.7
-
11
-
-
49449109723
-
The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis
-
McNeil, H. P., Shin, K., Campbell, I. K., Wicks, I. P., Adachi, R., Lee, D. M., and Stevens, R. L. (2008) The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis. Arthritis Rheum. 58, 2338-2346
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2338-2346
-
-
McNeil, H.P.1
Shin, K.2
Campbell, I.K.3
Wicks, I.P.4
Adachi, R.5
Lee, D.M.6
Stevens, R.L.7
-
12
-
-
34248194581
-
The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections
-
Thakurdas, S. M., Melicoff, E., Sansores-Garcia, L., Moreira, D. C., Petrova, Y., Stevens, R. L., and Adachi, R. (2007) The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J. Biol. Chem. 282, 20809-20815
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20809-20815
-
-
Thakurdas, S.M.1
Melicoff, E.2
Sansores-Garcia, L.3
Moreira, D.C.4
Petrova, Y.5
Stevens, R.L.6
Adachi, R.7
-
13
-
-
34447309788
-
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1
-
Schwertassek, U., Balmer, Y., Gutscher, M., Weingarten, L., Preuss, M., Engelhard, J., Winkler, M., and Dick, T. P. (2007) Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1. EMBO J. 26, 3086-3097
-
(2007)
EMBO J.
, vol.26
, pp. 3086-3097
-
-
Schwertassek, U.1
Balmer, Y.2
Gutscher, M.3
Weingarten, L.4
Preuss, M.5
Engelhard, J.6
Winkler, M.7
Dick, T.P.8
-
14
-
-
38449083939
-
Identification of redox-active cell-surface proteins by mechanism-based kinetic trapping
-
Schwertassek, U., Weingarten, L., and Dick, T. P. (2007) Identification of redox-active cell-surface proteins by mechanism-based kinetic trapping. Sci STKE 2007, pl8
-
(2007)
Sci STKE
, vol.2007
, pp. 18
-
-
Schwertassek, U.1
Weingarten, L.2
Dick, T.P.3
-
15
-
-
81155151848
-
Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain
-
Ganderton, T., Wong, J. W., Schroeder, C., and Hogg, P. J. (2011) Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain. Blood 118, 5312-5318
-
(2011)
Blood
, vol.118
, pp. 5312-5318
-
-
Ganderton, T.1
Wong, J.W.2
Schroeder, C.3
Hogg, P.J.4
-
16
-
-
0032190378
-
Protein identification at the low femtomole level from silverstained gels using a new fritless electrospray interface for liquid chromatography- microspray and nanospray mass spectrometry
-
Gatlin, C. L., Kleemann, G. R., Hays, L. G., Link, A. J., and Yates, J. R., 3rd. (1998) Protein identification at the low femtomole level from silverstained gels using a new fritless electrospray interface for liquid chromatography- microspray and nanospray mass spectrometry. Anal. Biochem. 263, 93-101
-
(1998)
Anal. Biochem
, vol.263
, pp. 93-101
-
-
Gatlin, C.L.1
Kleemann, G.R.2
Hays, L.G.3
Link, A.J.4
Yates III, J.R.5
-
17
-
-
0026781216
-
Equilibrium and kinetic constants for the thiol-disulfide interchange reaction between glutathione and dithiothreitol
-
Rothwarf, D. M., and Scheraga, H. A. (1992) Equilibrium and kinetic constants for the thiol-disulfide interchange reaction between glutathione and dithiothreitol. Proc. Natl. Acad. Sci. U.S.A. 89, 7944-7948
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 7944-7948
-
-
Rothwarf, D.M.1
Scheraga, H.A.2
-
18
-
-
0028292019
-
Phenotypic characterization of the human mast-cell line HMC-1
-
Nilsson, G., Blom, T., Kusche-Gullberg, M., Kjellén, L., Butterfield, J. H., Sundström, C., Nilsson, K., and Hellman, L. (1994) Phenotypic characterization of the human mast-cell line HMC-1. Scand. J. Immunol. 39, 489-498
-
(1994)
Scand. J. Immunol
, vol.39
, pp. 489-498
-
-
Nilsson, G.1
Blom, T.2
Kusche-Gullberg, M.3
Kjellén, L.4
Butterfield, J.H.5
Sundström, C.6
Nilsson, K.7
Hellman, L.8
-
20
-
-
2642600031
-
Human β-tryptase is a ring-like tetramer with active sites facing a central pore
-
Pereira, P. J., Bergner, A., Macedo-Ribeiro, S., Huber, R., Matschiner, G., Fritz, H., Sommerhoff, C. P., and Bode, W. (1998) Human β-tryptase is a ring-like tetramer with active sites facing a central pore. Nature 392, 306-311
-
(1998)
Nature
, vol.392
, pp. 306-311
-
-
Pereira, P.J.1
Bergner, A.2
MacEdo-Ribeiro, S.3
Huber, R.4
Matschiner, G.5
Fritz, H.6
Sommerhoff, C.P.7
Bode, W.8
-
21
-
-
0032519918
-
Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6
-
Huang, C., Friend, D. S., Qiu, W. T., Wong, G. W., Morales, G., Hunt, J., and Stevens, R. L. (1998) Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6. J. Immunol. 160, 1910-1919
-
(1998)
J. Immunol
, vol.160
, pp. 1910-1919
-
-
Huang, C.1
Friend, D.S.2
Qiu, W.T.3
Wong, G.W.4
Morales, G.5
Hunt, J.6
Stevens, R.L.7
-
22
-
-
33845428642
-
Thioredoxin and related molecules. from biology to health and disease
-
Lillig, C. H., and Holmgren, A. (2007) Thioredoxin and related molecules. From biology to health and disease. Antioxid. Redox Signal. 9, 25-47
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 25-47
-
-
Lillig, C.H.1
Holmgren, A.2
-
23
-
-
0037417177
-
Elevated serum levels of thioredoxin in patients with acute exacerbation of asthma
-
Yamada, Y., Nakamura, H., Adachi, T., Sannohe, S., Oyamada, H., Kayaba, H., Yodoi, J., and Chihara, J. (2003) Elevated serum levels of thioredoxin in patients with acute exacerbation of asthma. Immunol. Lett. 86, 199-205
-
(2003)
Immunol. Lett
, vol.86
, pp. 199-205
-
-
Yamada, Y.1
Nakamura, H.2
Adachi, T.3
Sannohe, S.4
Oyamada, H.5
Kayaba, H.6
Yodoi, J.7
Chihara, J.8
-
24
-
-
22844442461
-
Thioredoxin. Friend or foe in human disease?
-
Burke-Gaffney, A., Callister, M. E., and Nakamura, H. (2005) Thioredoxin. Friend or foe in human disease? Trends Pharmacol. Sci. 26, 398-404
-
(2005)
Trends Pharmacol. Sci
, vol.26
, pp. 398-404
-
-
Burke-Gaffney, A.1
Callister, M.E.2
Nakamura, H.3
-
25
-
-
18244381844
-
Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis
-
Jikimoto, T., Nishikubo, Y., Koshiba, M., Kanagawa, S., Morinobu, S., Morinobu, A., Saura, R., Mizuno, K., Kondo, S., Toyokuni, S., Nakamura, H., Yodoi, J., and Kumagai, S. (2002) Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis. Mol. Immunol. 38, 765-772
-
(2002)
Mol. Immunol
, vol.38
, pp. 765-772
-
-
Jikimoto, T.1
Nishikubo, Y.2
Koshiba, M.3
Kanagawa, S.4
Morinobu, S.5
Morinobu, A.6
Saura, R.7
Mizuno, K.8
Kondo, S.9
Toyokuni, S.10
Nakamura, H.11
Yodoi, J.12
Kumagai, S.13
-
26
-
-
33645830258
-
High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis
-
Lemarechal, H., Allanore, Y., Chenevier-Gobeaux, C., Ekindjian, O. G., Kahan, A., and Borderie, D. (2006) High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis. Clin. Chim. Acta 367, 156-161
-
(2006)
Clin. Chim. Acta
, vol.367
, pp. 156-161
-
-
Lemarechal, H.1
Allanore, Y.2
Chenevier-Gobeaux, C.3
Ekindjian, O.G.4
Kahan, A.5
Borderie, D.6
-
27
-
-
0025162150
-
Interactions of human mast cell tryptase with biological protease inhibitors
-
Alter, S. C., Kramps, J. A., Janoff, A., and Schwartz, L. B. (1990) Interactions of human mast cell tryptase with biological protease inhibitors. Arch. Biochem. Biophys. 276, 26-31
-
(1990)
Arch. Biochem. Biophys
, vol.276
, pp. 26-31
-
-
Alter, S.C.1
Kramps, J.A.2
Janoff, A.3
Schwartz, L.B.4
-
28
-
-
0033538454
-
Human tryptases α and β/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft
-
Huang, C. (1999) Human tryptases α and β/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft. J. Biol. Chem. 274, 19670-19676
-
(1999)
J. Biol. Chem
, vol.274
, pp. 19670-19676
-
-
Huang, C.1
-
29
-
-
0036385841
-
The crystal structure of human α1-tryptase reveals a blocked substratebinding region
-
Marquardt, U., Zettl, F., Huber, R., Bode, W., and Sommerhoff, C. (2002) The crystal structure of human α1-tryptase reveals a blocked substratebinding region. J. Mol. Biol. 321, 491-502
-
(2002)
J. Mol. Biol
, vol.321
, pp. 491-502
-
-
Marquardt, U.1
Zettl, F.2
Huber, R.3
Bode, W.4
Sommerhoff, C.5
-
30
-
-
0037066138
-
Diverse stability and catalytic properties of human tryptase α and β isoforms are mediated by residue differences at the S1 pocket
-
Selwood, T., Wang, Z. M., McCaslin, D. R., and Schechter, N. M. (2002) Diverse stability and catalytic properties of human tryptase α and β isoforms are mediated by residue differences at the S1 pocket. Biochemistry 41, 3329-3340
-
(2002)
Biochemistry
, vol.41
, pp. 3329-3340
-
-
Selwood, T.1
Wang, Z.M.2
McCaslin, D.R.3
Schechter, N.M.4
-
31
-
-
0023266455
-
Measurement of the internal pH of mast cell granules using microvolumetric fluorescence and isotopic techniques
-
De Young, M. B., Nemeth, E. F., and Scarpa, A. (1987) Measurement of the internal pH of mast cell granules using microvolumetric fluorescence and isotopic techniques. Arch. Biochem. Biophys. 254, 222-233
-
(1987)
Arch. Biochem. Biophys
, vol.254
, pp. 222-233
-
-
De Young, M.B.1
Nemeth, E.F.2
Scarpa, A.3
-
32
-
-
0019329756
-
The internal pH of mast cell granules
-
Johnson, R. G., Carty, S. E., Fingerhood, B. J., and Scarpa, A. (1980) The internal pH of mast cell granules. FEBS Lett. 120, 75-79
-
(1980)
FEBS Lett
, vol.120
, pp. 75-79
-
-
Johnson, R.G.1
Carty, S.E.2
Fingerhood, B.J.3
Scarpa, A.4
-
33
-
-
0020639034
-
Evidence for control of mast cell granule protease in situ by low pH
-
Lagunoff, D., and Rickard, A. (1983) Evidence for control of mast cell granule protease in situ by low pH. Exp. Cell Res. 144, 353-360
-
(1983)
Exp. Cell Res
, vol.144
, pp. 353-360
-
-
Lagunoff, D.1
Rickard, A.2
-
34
-
-
0021832906
-
Significance of the hydrogen ion concentration in synovial fluid in rheumatoid arthritis
-
Farr, M., Garvey, K., Bold, A. M., Kendall, M. J., and Bacon, P. A. (1985) Significance of the hydrogen ion concentration in synovial fluid in rheumatoid arthritis. Clin. Exp. Rheumatol. 3, 99-104
-
(1985)
Clin. Exp. Rheumatol
, vol.3
, pp. 99-104
-
-
Farr, M.1
Garvey, K.2
Bold, A.M.3
Kendall, M.J.4
Bacon, P.A.5
-
35
-
-
0024314320
-
Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints
-
Geborek, P., Saxne, T., Pettersson, H., and Wollheim, F. A. (1989) Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints. J. Rheumatol. 16, 468-472
-
(1989)
J. Rheumatol
, vol.16
, pp. 468-472
-
-
Geborek, P.1
Saxne, T.2
Pettersson, H.3
Wollheim, F.A.4
-
36
-
-
0034104692
-
Endogenous airway acidification. Implications for asthma pathophysiology
-
Hunt, J. F., Fang, K., Malik, R., Snyder, A., Malhotra, N., Platts-Mills, T. A., and Gaston, B. (2000) Endogenous airway acidification. Implications for asthma pathophysiology. Am. J. Respir. Crit. Care Med. 161, 694-699
-
(2000)
Am. J. Respir. Crit. Care Med
, vol.161
, pp. 694-699
-
-
Hunt, J.F.1
Fang, K.2
Malik, R.3
Snyder, A.4
Malhotra, N.5
Platts-Mills, T.A.6
Gaston, B.7
-
37
-
-
34247589697
-
An investigation of airway acidification in asthma using induced sputum. A study of feasibility and correlation
-
Kodric, M., Shah, A. N., Fabbri, L. M., and Confalonieri, M. (2007) An investigation of airway acidification in asthma using induced sputum. A study of feasibility and correlation. Am. J. Respir. Crit. Care Med. 175, 905-910
-
(2007)
Am. J. Respir. Crit. Care Med
, vol.175
, pp. 905-910
-
-
Kodric, M.1
Shah, A.N.2
Fabbri, L.M.3
Confalonieri, M.4
-
38
-
-
0037330931
-
Formation of active monomers from tetrameric human β-tryptase
-
Fajardo, I., and Pejler, G. (2003) Formation of active monomers from tetrameric human β-tryptase. Biochem. J. 369, 603-610
-
(2003)
Biochem J.
, vol.369
, pp. 603-610
-
-
Fajardo, I.1
Pejler, G.2
-
39
-
-
4143123236
-
Human β-tryptase. Detection and characterization of the active monomer and prevention of tetramer reconstitution by protease inhibitors
-
Fukuoka, Y., and Schwartz, L. B. (2004) Human β-tryptase. Detection and characterization of the active monomer and prevention of tetramer reconstitution by protease inhibitors. Biochemistry 43, 10757-10764
-
(2004)
Biochemistry
, vol.43
, pp. 10757-10764
-
-
Fukuoka, Y.1
Schwartz, L.B.2
-
40
-
-
33644500443
-
The B12 anti-tryptase monoclonal antibody disrupts the tetrameric structure of heparin-stabilized β-tryptase to form monomers that are inactive at neutral pH and active at acidic pH
-
Fukuoka, Y., and Schwartz, L. B. (2006) The B12 anti-tryptase monoclonal antibody disrupts the tetrameric structure of heparin-stabilized β-tryptase to form monomers that are inactive at neutral pH and active at acidic pH. J. Immunol. 176, 3165-3172
-
(2006)
J. Immunol
, vol.176
, pp. 3165-3172
-
-
Fukuoka, Y.1
Schwartz, L.B.2
-
41
-
-
9644262525
-
Structural requirements and mechanism for heparin-dependent activation and tetramerization of human βi- and βiI-tryptase
-
Hallgren, J., Lindahl, S., and Pejler, G. (2005) Structural requirements and mechanism for heparin-dependent activation and tetramerization of human βI- and βII-tryptase. J. Mol. Biol. 345, 129-139
-
(2005)
J. Mol. Biol
, vol.345
, pp. 129-139
-
-
Hallgren, J.1
Lindahl, S.2
Pejler, G.3
-
42
-
-
0022388692
-
The fibrinogenolytic activity of purified tryptase from human lung mast cells
-
Schwartz, L. B., Bradford, T. R., Littman, B. H., and Wintroub, B. U. (1985) The fibrinogenolytic activity of purified tryptase from human lung mast cells. J. Immunol. 135, 2762-2767
-
(1985)
J. Immunol
, vol.135
, pp. 2762-2767
-
-
Schwartz, L.B.1
Bradford, T.R.2
Littman, B.H.3
Wintroub, B.U.4
-
43
-
-
0031255314
-
Human tryptase fibrinogenolysis is optimal at acidic pH and generates anticoagulant fragments in the presence of the anti-tryptase monoclonal antibody B12
-
Ren, S., Lawson, A. E., Carr, M., Baumgarten, C. M., and Schwartz, L. B. (1997) Human tryptase fibrinogenolysis is optimal at acidic pH and generates anticoagulant fragments in the presence of the anti-tryptase monoclonal antibody B12. J. Immunol. 159, 3540-3548
-
(1997)
J. Immunol
, vol.159
, pp. 3540-3548
-
-
Ren, S.1
Lawson, A.E.2
Carr, M.3
Baumgarten, C.M.4
Schwartz, L.B.5
-
44
-
-
1842509220
-
Sequence and evolutionary analysis of the human trypsin subfamily of serine peptidases
-
Yousef, G. M., Elliott, M. B., Kopolovic, A. D., Serry, E., and Diamandis, E. P. (2004) Sequence and evolutionary analysis of the human trypsin subfamily of serine peptidases. Biochim. Biophys. Acta 1698, 77-86
-
(2004)
Biochim. Biophys. Acta
, vol.1698
, pp. 77-86
-
-
Yousef, G.M.1
Elliott, M.B.2
Kopolovic, A.D.3
Serry, E.4
Diamandis, E.P.5
-
45
-
-
0024853669
-
Coagulation factor XII (Hageman factor) Washington D.C. Inactive factor XIIa results from Cys-571-Ser substitution
-
Miyata, T., Kawabata, S., Iwanaga, S., Takahashi, I., Alving, B., and Saito, H. (1989) Coagulation factor XII (Hageman factor) Washington D.C. Inactive factor XIIa results from Cys-571-Ser substitution. Proc. Natl. Acad. Sci. U.S.A. 86, 8319-8322
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 8319-8322
-
-
Miyata, T.1
Kawabata, S.2
Iwanaga, S.3
Takahashi, I.4
Alving, B.5
Saito, H.6
-
46
-
-
34848874846
-
Important role of the Cys-191 Cys-220 disulfide bond in thrombin function and allostery
-
Bush-Pelc, L. A., Marino, F., Chen, Z., Pineda, A. O., Mathews, F. S., and Di Cera, E. (2007) Important role of the Cys-191 Cys-220 disulfide bond in thrombin function and allostery. J. Biol. Chem. 282, 27165-27170
-
(2007)
J. Biol. Chem
, vol.282
, pp. 27165-27170
-
-
Bush-Pelc, L.A.1
Marino, F.2
Chen, Z.3
Pineda, A.O.4
Mathews, F.S.5
Di Cera, E.6
-
47
-
-
0030904228
-
The role of the Cys191-Cys220 disulfide bond in trypsin. New targets for engineering substrate specificity
-
Wang, E. C., Hung, S. H., Cahoon, M., and Hedstrom, L. (1997) The role of the Cys191-Cys220 disulfide bond in trypsin. New targets for engineering substrate specificity. Protein Eng. 10, 405-411
-
(1997)
Protein Eng
, vol.10
, pp. 405-411
-
-
Wang, E.C.1
Hung, S.H.2
Cahoon, M.3
Hedstrom, L.4
-
48
-
-
0031584097
-
The role of disulfide bond C191-C220 in trypsin and chymotrypsin
-
Várallyay, E., Lengyel, Z., Gráf, L., and Szilágyi, L. (1997) The role of disulfide bond C191-C220 in trypsin and chymotrypsin. Biochem. Biophys. Res. Commun. 230, 592-596
-
(1997)
Biochem. Biophys. Res. Commun
, vol.230
, pp. 592-596
-
-
Várallyay, E.1
Lengyel, Z.2
Gráf, L.3
Szilágyi, L.4
-
49
-
-
84876114193
-
Post-translational control of protein function by disulfide bond cleavage
-
Cook, K. M., and Hogg, P. J. (2013) Post-translational control of protein function by disulfide bond cleavage. Antioxid. Redox Signal. 18, 1987-2015
-
(2013)
Antioxid. Redox Signal
, vol.18
, pp. 1987-2015
-
-
Cook, K.M.1
Hogg, P.J.2
-
50
-
-
84878240943
-
Targeting allosteric disulphide bonds in cancer
-
Hogg, P. J. (2013) Targeting allosteric disulphide bonds in cancer. Nat. Rev. Cancer 13, 425-431
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 425-431
-
-
Hogg, P.J.1
-
51
-
-
33745161382
-
Allosteric disulfide bonds
-
Schmidt, B., Ho, L., and Hogg, P. J. (2006) Allosteric disulfide bonds. Biochemistry 45, 7429-7433
-
(2006)
Biochemistry
, vol.45
, pp. 7429-7433
-
-
Schmidt, B.1
Ho, L.2
Hogg, P.J.3
-
52
-
-
34547891553
-
Search for allosteric disulfide bonds in NMR structures
-
Schmidt, B., and Hogg, P. J. (2007) Search for allosteric disulfide bonds in NMR structures. BMC Struct. Biol. 7, 49
-
(2007)
BMC Struct. Biol
, vol.7
, pp. 49
-
-
Schmidt, B.1
Hogg, P.J.2
-
53
-
-
81155133905
-
Analysis of disulfide bonds in protein structures
-
Wong, J. W., and Hogg, P. J. (2010) Analysis of disulfide bonds in protein structures. J. Thromb. Haemost. 8, 2345
-
(2010)
J. Thromb. Haemost
, vol.8
, pp. 2345
-
-
Wong, J.W.1
Hogg, P.J.2
-
54
-
-
38049035093
-
TRPC channel activation by extracellular thioredoxin
-
Xu, S. Z., Sukumar, P., Zeng, F., Li, J., Jairaman, A., English, A., Naylor, J., Ciurtin, C., Majeed, Y., Milligan, C. J., Bahnasi, Y. M., Al-Shawaf, E., Porter, K. E., Jiang, L. H., Emery, P., Sivaprasadarao, A., and Beech, D. J. (2008) TRPC channel activation by extracellular thioredoxin. Nature 451, 69-72
-
(2008)
Nature
, vol.451
, pp. 69-72
-
-
Xu, S.Z.1
Sukumar, P.2
Zeng, F.3
Li, J.4
Jairaman, A.5
English, A.6
Naylor, J.7
Ciurtin, C.8
Majeed, Y.9
Milligan, C.J.10
Bahnasi, Y.M.11
Al-Shawaf, E.12
Porter, K.E.13
Jiang, L.H.14
Emery, P.15
Sivaprasadarao, A.16
Beech, D.J.17
-
55
-
-
0033593450
-
Redox control of exofacial protein thiols/disulfides by protein disulfide isomerase
-
Jiang, X. M., Fitzgerald, M., Grant, C. M., and Hogg, P. J. (1999) Redox control of exofacial protein thiols/disulfides by protein disulfide isomerase. J. Biol. Chem. 274, 2416-2423
-
(1999)
J. Biol. Chem
, vol.274
, pp. 2416-2423
-
-
Jiang, X.M.1
Fitzgerald, M.2
Grant, C.M.3
Hogg, P.J.4
-
56
-
-
34547851612
-
Innate immune recognition triggers secretion of lysosomal enzymes by macrophages
-
Lackman, R. L., Jamieson, A. M., Griffith, J. M., Geuze, H., and Cresswell, P. (2007) Innate immune recognition triggers secretion of lysosomal enzymes by macrophages. Traffic 8, 1179-1189
-
(2007)
Traffic
, vol.8
, pp. 1179-1189
-
-
Lackman, R.L.1
Jamieson, A.M.2
Griffith, J.M.3
Geuze, H.4
Cresswell, P.5
-
57
-
-
84862550998
-
Labile disulfide bonds are common at the leucocyte cell surface
-
Metcalfe, C., Cresswell, P., Ciaccia, L., Thomas, B., and Barclay, A. N. (2011) Labile disulfide bonds are common at the leucocyte cell surface. Open Biol. 1, 110010
-
(2011)
Open Biol
, vol.1
, pp. 110010
-
-
Metcalfe, C.1
Cresswell, P.2
Ciaccia, L.3
Thomas, B.4
Barclay, A.N.5
-
58
-
-
0034714333
-
γ-Interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action
-
Phan, U. T., Arunachalam, B., and Cresswell, P. (2000) γ-Interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action. J. Biol. Chem. 275, 25907-25914
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25907-25914
-
-
Phan, U.T.1
Arunachalam, B.2
Cresswell, P.3
-
59
-
-
0023567897
-
Regulation of human mast cell tryptase. Effects of enzyme concentration, ionic strength and the structure and negative charge density of polysaccharides
-
Alter, S. C., Metcalfe, D. D., Bradford, T. R., and Schwartz, L. B. (1987) Regulation of human mast cell tryptase. Effects of enzyme concentration, ionic strength and the structure and negative charge density of polysaccharides. Biochem. J. 248, 821-827
-
(1987)
Biochem. J.
, vol.248
, pp. 821-827
-
-
Alter, S.C.1
Metcalfe, D.D.2
Bradford, T.R.3
Schwartz, L.B.4
-
60
-
-
0022872843
-
Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer
-
Schwartz, L. B., and Bradford, T. R. (1986) Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer. J. Biol. Chem. 261, 7372-7379
-
(1986)
J. Biol. Chem
, vol.261
, pp. 7372-7379
-
-
Schwartz, L.B.1
Bradford, T.R.2
-
62
-
-
84862806090
-
A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
-
Liang, G., Choi-Sledeski, Y. M., Shum, P., Chen, X., Poli, G. B., Kumar, V., Minnich, A., Wang, Q., Tsay, J., Sides, K., Kang, J., and Zhang, Y. (2012) A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity. Bioorg. Med. Chem. Lett. 22, 1606-1610
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 1606-1610
-
-
Liang, G.1
Choi-Sledeski, Y.M.2
Shum, P.3
Chen, X.4
Poli, G.B.5
Kumar, V.6
Minnich, A.7
Wang, Q.8
Tsay, J.9
Sides, K.10
Kang, J.11
Zhang, Y.12
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