메뉴 건너뛰기




Volumn 73, Issue 16, 2013, Pages 1815-1827

Tobramycin inhalation powder: A review of its use in the treatment of chronic pseudomonas aeruginosa infection in patients with cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BRONCHODILATING AGENT; MUCOLYTIC AGENT; PLACEBO; SODIUM CHLORIDE; TOBRAMYCIN;

EID: 84889000280     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-013-0141-0     Document Type: Review
Times cited : (24)

References (47)
  • 1
    • 80053377162 scopus 로고    scopus 로고
    • TM: A novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis
    • 21955231 10.1586/ers.11.56 1:CAS:528:DC%2BC3MXht1Clur3N
    • TM: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis. Expert Rev Respir Med. 2011;5(5):609-22.
    • (2011) Expert Rev Respir Med. , vol.5 , Issue.5 , pp. 609-622
    • Parkins, M.D.1    Elborn, J.S.2
  • 2
    • 84889073216 scopus 로고    scopus 로고
    • Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: A review
    • 10.2147/MDER.S16360 22915944
    • VanDevanter DR, Geller DE. Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: a review. Med Devices (Auckl). 2011. doi: 10.2147/MDER.S16360.
    • (2011) Med Devices (Auckl).
    • Vandevanter, D.R.1    Geller, D.E.2
  • 3
    • 51349100398 scopus 로고    scopus 로고
    • The prevalence of cystic fibrosis in the European Union
    • 18442953 10.1016/j.jcf.2008.03.007
    • Farrell PM. The prevalence of cystic fibrosis in the European Union. J Cyst Fibros. 2008;7:450-3.
    • (2008) J Cyst Fibros. , vol.7 , pp. 450-453
    • Farrell, P.M.1
  • 4
    • 79953262396 scopus 로고    scopus 로고
    • Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
    • 21463524 10.1186/1741-7015-9-32
    • Høiby N. Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med. 2011;9:32.
    • (2011) BMC Med. , vol.9 , pp. 32
    • Høiby, N.1
  • 5
    • 36248953255 scopus 로고    scopus 로고
    • Cystic fibrosis pulmonary guidelines: Chronic medications for maintenance of lung health
    • 17761616 10.1164/rccm.200705-664OC 1:CAS:528:DC%2BD2sXhsVekt77N
    • Flume PA, O'Sullivan BP, Robinson KA, et al. Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med. 2007;176(10):957-69.
    • (2007) Am J Respir Crit Care Med. , vol.176 , Issue.10 , pp. 957-969
    • Flume, P.A.1    O'Sullivan, B.P.2    Robinson, K.A.3
  • 6
    • 66849142486 scopus 로고    scopus 로고
    • Aerosol antibiotics in cystic fibrosis
    • 19393109 10.4187/aarc0537
    • Geller DE. Aerosol antibiotics in cystic fibrosis. Respir Care. 2009;54(5):658-69.
    • (2009) Respir Care. , vol.54 , Issue.5 , pp. 658-669
    • Geller, D.E.1
  • 7
    • 0142043977 scopus 로고    scopus 로고
    • Pathophysiology and management of pulmonary infections in cystic fibrosis
    • 14555458 10.1164/rccm.200304-505SO
    • Gibson RL, Burns JL, Ramsey BW. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med. 2003;168(8):918-51.
    • (2003) Am J Respir Crit Care Med. , vol.168 , Issue.8 , pp. 918-951
    • Gibson, R.L.1    Burns, J.L.2    Ramsey, B.W.3
  • 8
    • 0242609342 scopus 로고    scopus 로고
    • ®): A review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis
    • 14609360 10.2165/00003495-200363220-00015 1:CAS:528:DC%2BD3sXpvFShsLg%3D
    • ®): a review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis. Drugs. 2003;63:2501-20.
    • (2003) Drugs. , vol.63 , pp. 2501-2520
    • Cheer, S.M.1    Waugh, J.2    Noble, S.3
  • 9
    • 60449117029 scopus 로고    scopus 로고
    • High treatment burden in adults with cystic fibrosis: Challenges to disease self management
    • 18952504 10.1016/j.jcf.2008.09.007
    • Sawicki GS, Sellers DE, Robinson WM, et al. High treatment burden in adults with cystic fibrosis: challenges to disease self management. J Cyst Fibros. 2009;8(2):91-6.
    • (2009) J Cyst Fibros. , vol.8 , Issue.2 , pp. 91-96
    • Sawicki, G.S.1    Sellers, D.E.2    Robinson, W.M.3
  • 10
    • 85081791022 scopus 로고    scopus 로고
    • European Medicines Agency Summary of product characteristics Accessed 17 Oct 2013
    • European Medicines Agency. TOBI Podhaler 28 mg inhalation powder, hard capsules. Summary of product characteristics. 2011. http://www.ema.europa.eu/ docs/en-GB/document-library/EPAR-Product-Information/human/002155/WC500110921. pdf. Accessed 17 Oct 2013.
    • (2011) TOBI Podhaler 28 Mg Inhalation Powder, Hard Capsules
  • 11
    • 34547464547 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals Corporation. TOBI PODHALER (Tobramycin Inhalation Powder) Accessed 17 Oct 2013
    • Novartis Pharmaceuticals Corporation. TOBI PODHALER (Tobramycin Inhalation Powder). Full prescribing information. 2013. http://www.pharma.us. novartis.com/cs/www.pharma.us.novartis.com/product/pi/pdf/tobipodhaler.pdf. Accessed 17 Oct 2013.
    • (2013) Full Prescribing Information
  • 12
    • 70449687936 scopus 로고    scopus 로고
    • Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: A review
    • 19747887 10.1016/j.jcf.2009.08.004 1:CAS:528:DC%2BD1MXhsVGmsLnN
    • Ratjen F, Brockhaus F, Angyalosi G. Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: a review. J Cyst Fibros. 2009;8(6):361-9.
    • (2009) J Cyst Fibros. , vol.8 , Issue.6 , pp. 361-369
    • Ratjen, F.1    Brockhaus, F.2    Angyalosi, G.3
  • 13
    • 84862487763 scopus 로고    scopus 로고
    • Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis
    • 22445849 10.1016/j.jcf.2012.02.005
    • Ren CL, Konstan MW, Yegin A, et al. Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis. J Cyst Fibros. 2012;11(4):293-9.
    • (2012) J Cyst Fibros. , vol.11 , Issue.4 , pp. 293-299
    • Ren, C.L.1    Konstan, M.W.2    Yegin, A.3
  • 14
    • 0033531143 scopus 로고    scopus 로고
    • Intermittent administration of inhaled tobramycin in patients with cystic fibrosis
    • 9878641 10.1056/NEJM199901073400104 1:CAS:528:DyaK1MXltFeltw%3D%3D
    • Ramsey BW, Pepe MS, Quan JM, et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. N Engl J Med. 1999;340:23-30.
    • (1999) N Engl J Med. , vol.340 , pp. 23-30
    • Ramsey, B.W.1    Pepe, M.S.2    Quan, J.M.3
  • 15
    • 69549135253 scopus 로고    scopus 로고
    • Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus
    • 19559658 10.1016/j.jcf.2009.04.005 1:CAS:528:DC%2BD1MXhtV2rsL7I
    • Heijerman H, Westerman E, Conway S, et al. Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: a European consensus. J Cyst Fibros. 2009;8(5):295-315.
    • (2009) J Cyst Fibros. , vol.8 , Issue.5 , pp. 295-315
    • Heijerman, H.1    Westerman, E.2    Conway, S.3
  • 17
    • 0038826781 scopus 로고    scopus 로고
    • Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers
    • 12853545 10.1378/chest.124.1.360 1:CAS:528:DC%2BD3sXmsFClt7s%3D
    • Newhouse MT, Hirst PH, Duddu SP, et al. Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers. Chest. 2003;124(1):360-6.
    • (2003) Chest. , vol.124 , Issue.1 , pp. 360-366
    • Newhouse, M.T.1    Hirst, P.H.2    Duddu, S.P.3
  • 18
    • 33846068813 scopus 로고    scopus 로고
    • Effect of dry powder inhaler resistance on the inspiratory flow rates and volumes of cystic fibrosis patients of six years and older
    • 17196074 10.1089/jam.2006.19.456 1:CAS:528:DC%2BD28XhtlGqtLzJ
    • Tiddens HA, Geller DE, Challoner P, et al. Effect of dry powder inhaler resistance on the inspiratory flow rates and volumes of cystic fibrosis patients of six years and older. J Aerosol Med. 2006;19(4):456-65.
    • (2006) J Aerosol Med. , vol.19 , Issue.4 , pp. 456-465
    • Tiddens, H.A.1    Geller, D.E.2    Challoner, P.3
  • 19
    • 84887747253 scopus 로고    scopus 로고
    • Inspiratory flow characteristics of the T-326 dry powder inhaler (DPI) in CF patients [abstract no. 72]
    • 10.1016/S1569-1993(13)60214-3
    • Geller D, Ament B, Heuerding S, et al. Inspiratory flow characteristics of the T-326 dry powder inhaler (DPI) in CF patients [abstract no. 72]. J Cyst Fibros. 2013;12(Suppl):S66.
    • (2013) J Cyst Fibros. , vol.12 , Issue.SUPPL. , pp. 66
    • Geller, D.1    Ament, B.2    Heuerding, S.3
  • 21
    • 34247193128 scopus 로고    scopus 로고
    • Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
    • 17352404 10.1002/ppul.20594
    • Geller DE, Konstan MW, Smith J, et al. Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediatr Pulmonol. 2007;42(4):307-13.
    • (2007) Pediatr Pulmonol. , vol.42 , Issue.4 , pp. 307-313
    • Geller, D.E.1    Konstan, M.W.2    Smith, J.3
  • 22
    • 84923149470 scopus 로고    scopus 로고
    • Reduced administration time for inhaled tobramycin in cystic fibrosis patients: Results from the EAGER trial [abstract]
    • 17-19 Oct 2013; Salt Lake City
    • Nasr S, Nick J, Ezzet N, et al. Reduced administration time for inhaled tobramycin in cystic fibrosis patients: results from the EAGER trial [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
    • 27th Annual North American Cystic Fibrosis Conference
    • Nasr, S.1    Nick, J.2    Ezzet, N.3
  • 23
    • 84876034477 scopus 로고    scopus 로고
    • Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin
    • 22620494 10.1089/jamp.2011.0942 1:CAS:528:DC%2BC3sXlsV2ltLs%3D
    • Ruddy J, Emerson J, Moss R, et al. Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin. J Aerosol Med Pulm Drug Deliv. 2013;26(2):69-75.
    • (2013) J Aerosol Med Pulm Drug Deliv. , vol.26 , Issue.2 , pp. 69-75
    • Ruddy, J.1    Emerson, J.2    Moss, R.3
  • 24
    • 84880473914 scopus 로고    scopus 로고
    • Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: The randomized EDIT trial
    • 23672633 10.1185/03007995.2013.805122 1:CAS:528:DC%2BC3sXhtFeqsLzI
    • Galeva I, Konstan MW, Higgins M, et al. Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: the randomized EDIT trial. Curr Med Res Opin. 2013;29(8):947-56.
    • (2013) Curr Med Res Opin. , vol.29 , Issue.8 , pp. 947-956
    • Galeva, I.1    Konstan, M.W.2    Higgins, M.3
  • 25
    • 79951840468 scopus 로고    scopus 로고
    • Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: The EVOLVE trial
    • 20963831 10.1002/ppul.21356
    • Konstan MW, Geller DE, Minic P, et al. Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: The EVOLVE trial. Pediatr Pulmonol. 2011;46(3):230-8.
    • (2011) Pediatr Pulmonol. , vol.46 , Issue.3 , pp. 230-238
    • Konstan, M.W.1    Geller, D.E.2    Minic, P.3
  • 26
    • 78651412529 scopus 로고    scopus 로고
    • Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial
    • 21075062 10.1016/j.jcf.2010.10.003 1:CAS:528:DC%2BC3MXntVGltw%3D%3D
    • Konstan MW, Flume PA, Kappler M, et al. Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial. J Cyst Fibros. 2011;10(1):54-61.
    • (2011) J Cyst Fibros. , vol.10 , Issue.1 , pp. 54-61
    • Konstan, M.W.1    Flume, P.A.2    Kappler, M.3
  • 27
    • 84923149467 scopus 로고    scopus 로고
    • Long-term safety and efficacy of tobramycin inhalation powder in cystic fibrosis patients with P. Aeruginosa: The EDIT trial and its two open-label extension studies [abstract]
    • 17-19 Oct 2013; Salt Lake City
    • Konstan MW, Flume PA, Wan R, et al. Long-term safety and efficacy of tobramycin inhalation powder in cystic fibrosis patients with P. aeruginosa: the EDIT trial and its two open-label extension studies [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
    • 27th Annual North American Cystic Fibrosis Conference
    • Konstan, M.W.1    Flume, P.A.2    Wan, R.3
  • 28
    • 84869087512 scopus 로고    scopus 로고
    • Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis
    • 22583743 10.1016/j.jcf.2012.04.007
    • Regnault A, Balp M-M, Kulich K, et al. Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis. J Cyst Fibros. 2012;11(6):494-501.
    • (2012) J Cyst Fibros. , vol.11 , Issue.6 , pp. 494-501
    • Regnault, A.1    Balp, M.-M.2    Kulich, K.3
  • 29
    • 85081794573 scopus 로고    scopus 로고
    • Association of treatment satisfaction and compliance of cystic fibrosis (CF) patients using inhaled tobramycin treatment in the EAGER study
    • 8-11 June 2011, Hamburg
    • Regnault A, Bal MM, Kulich K, et al. Association of treatment satisfaction and compliance of cystic fibrosis (CF) patients using inhaled tobramycin treatment in the EAGER study. 34th European Cystic Fibrosis Conference; 8-11 June 2011, Hamburg.
    • 34th European Cystic Fibrosis Conference
    • Regnault, A.1    Bal, M.M.2    Kulich, K.3
  • 30
    • 84888992940 scopus 로고    scopus 로고
    • Tobramycin inhalation powder in cystic fibrosis patients: Response by age group
    • 10.4187/respcare.02264 23983274
    • Geller DE, Nasr SZ, Piggott S, et al. Tobramycin inhalation powder in cystic fibrosis patients: response by age group. Respir Care. 2013. doi: 10.4187/respcare.02264.
    • (2013) Respir Care.
    • Geller, D.E.1    Nasr, S.Z.2    Piggott, S.3
  • 31
    • 84889046027 scopus 로고    scopus 로고
    • Improved tolerability, adherence and reduced intravenous (IV) antibiotic usage in CF patients receiving inhaled versus nebulised antibiotic prophylaxis. A real world comparison of tobramycin inhaled powder (TIP) and tobramycin inhaled solution (TIS) [abstract no. 74]
    • 10.1016/S1569-1993(13)60216-7
    • Harrison MJ, McCarthy C, Fleming C, et al. Improved tolerability, adherence and reduced intravenous (IV) antibiotic usage in CF patients receiving inhaled versus nebulised antibiotic prophylaxis. A real world comparison of tobramycin inhaled powder (TIP) and tobramycin inhaled solution (TIS) [abstract no. 74]. J Cyst Fibros. 2013;12(Suppl):S67.
    • (2013) J Cyst Fibros. , vol.12 , Issue.SUPPL. , pp. 67
    • Harrison, M.J.1    McCarthy, C.2    Fleming, C.3
  • 32
    • 84889020779 scopus 로고    scopus 로고
    • Comparison of pharmacy prescription refill frequency in CF adults before and after switching from tobramycin inhalation solution (TIS) to TOBI Podhaler: 'Real world' evidence of improved adherence [abstract no. 68]
    • 10.1016/S1569-1993(13)60210-6
    • Nash EF, Ahitan B, Brown CJ, et al. Comparison of pharmacy prescription refill frequency in CF adults before and after switching from tobramycin inhalation solution (TIS) to TOBI Podhaler: 'real world' evidence of improved adherence [abstract no. 68]. J Cyst Fibros. 2013;12(Suppl):S65.
    • (2013) J Cyst Fibros. , vol.12 , Issue.SUPPL. , pp. 65
    • Nash, E.F.1    Ahitan, B.2    Brown, C.J.3
  • 34
    • 4544330253 scopus 로고    scopus 로고
    • Cystic Fibrosis Foundation Accessed 21 Aug 2013
    • Cystic Fibrosis Foundation. Patient registry: annual data report. 2011. http://www.cff.org/LivingWithCF/QualityImprovement/PatientRegistryReport/. Accessed 21 Aug 2013.
    • (2011) Patient Registry: Annual Data Report
  • 35
    • 3343023861 scopus 로고    scopus 로고
    • Early intervention and prevention of lung disease in cystic fibrosis: A European consensus
    • 15463891 10.1016/j.jcf.2004.03.008
    • Doring G, Hoiby N. Early intervention and prevention of lung disease in cystic fibrosis: a European consensus. J Cyst Fibros. 2004;3:67-91.
    • (2004) J Cyst Fibros. , vol.3 , pp. 67-91
    • Doring, G.1    Hoiby, N.2
  • 36
    • 84866172783 scopus 로고    scopus 로고
    • A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis
    • 22717535 10.1016/j.jcf.2012.03.010 1:CAS:528:DC%2BC38XhtlOjurrK
    • Littlewood KJ, Higashi K, Jansen JP, et al. A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis. J Cyst Fibros. 2012;11(5):419-26.
    • (2012) J Cyst Fibros. , vol.11 , Issue.5 , pp. 419-426
    • Littlewood, K.J.1    Higashi, K.2    Jansen, J.P.3
  • 37
    • 84155165377 scopus 로고    scopus 로고
    • Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution
    • 21815282 10.1002/ppul.21521
    • Sawicki GS, Signorovitch JE, Zhang J, et al. Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution. Pediatr Pulmonol. 2012;47(1):44-52.
    • (2012) Pediatr Pulmonol. , vol.47 , Issue.1 , pp. 44-52
    • Sawicki, G.S.1    Signorovitch, J.E.2    Zhang, J.3
  • 38
    • 4544269731 scopus 로고    scopus 로고
    • Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease
    • 15334509 10.1002/ppul.20097
    • Murphy TD, Anbar RD, Lester LA, et al. Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease. Pediatr Pulmonol. 2004;38(4):314-20.
    • (2004) Pediatr Pulmonol. , vol.38 , Issue.4 , pp. 314-320
    • Murphy, T.D.1    Anbar, R.D.2    Lester, L.A.3
  • 39
    • 0036157901 scopus 로고    scopus 로고
    • Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis
    • 11796432 10.1378/chest.121.1.55 1:CAS:528:DC%2BD38Xht1yltbs%3D
    • Moss RB. Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis. Chest. 2002;121(1):55-63.
    • (2002) Chest. , vol.121 , Issue.1 , pp. 55-63
    • Moss, R.B.1
  • 41
    • 85081799491 scopus 로고    scopus 로고
    • Convenience and stated adherence for antibiotic treatment of cystic-fibrosis pseudomonas infections [abstract]
    • 17-19 Oct 2013; Salt Lake City
    • Mohamed AF, Reed Johnson FR, Balp MM, et al. Convenience and stated adherence for antibiotic treatment of cystic-fibrosis pseudomonas infections [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
    • 27th Annual North American Cystic Fibrosis Conference
    • Mohamed, A.F.1    Reed Johnson, F.R.2    Balp, M.M.3
  • 42
    • 84864283580 scopus 로고    scopus 로고
    • In vitro prevention of Pseudomonas aeruginosa early biofilm formation with antibiotics used in cystic fibrosis patients
    • 22727530 10.1016/j.ijantimicag.2012.04.006 1:CAS:528:DC%2BC38XptVKls7g%3D
    • Fernandez-Olmos A, Garcia-Castillo M, Maiz L, et al. In vitro prevention of Pseudomonas aeruginosa early biofilm formation with antibiotics used in cystic fibrosis patients. Int J Antimicrob Agents. 2012;40(2):173-6.
    • (2012) Int J Antimicrob Agents. , vol.40 , Issue.2 , pp. 173-176
    • Fernandez-Olmos, A.1    Garcia-Castillo, M.2    Maiz, L.3
  • 43
    • 84870768231 scopus 로고    scopus 로고
    • Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colinized by P. Aeruginosa
    • Schelstraete P, Haerynck F, Van daele S, et al. Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colinized by P. aeruginosa. J Cyst Fibros. 2013;12:1-8.
    • (2013) J Cyst Fibros , vol.12 , pp. 1-8
    • Schelstraete, P.1    Haerynck, F.2    Van Daele, S.3
  • 44
    • 84855279786 scopus 로고    scopus 로고
    • Aerosolized antibiotic therapy for chronic cystic fibrosis airway infections: Continuous or intermittent?
    • 10.1016/S0954-6111(11)70022-1
    • Lo D, VanDevanter DR, Flume P, et al. Aerosolized antibiotic therapy for chronic cystic fibrosis airway infections: continuous or intermittent? Resp Med. 2011;105(Suppl 2):S9-17.
    • (2011) Resp Med. , vol.105 , Issue.SUPPL.
    • Lo, D.1    Vandevanter, D.R.2    Flume, P.3
  • 45
    • 70349096824 scopus 로고    scopus 로고
    • Emerging treatments in cystic fibrosis
    • 19747007 10.2165/11318500-000000000-00000 1:CAS:528:DC%2BD1MXhtlOrsLbO
    • Jones AM, Helm JM. Emerging treatments in cystic fibrosis. Drugs. 2009;69(14):1903-10.
    • (2009) Drugs. , vol.69 , Issue.14 , pp. 1903-1910
    • Jones, A.M.1    Helm, J.M.2
  • 46
    • 78049402553 scopus 로고    scopus 로고
    • New antimicrobial strategies in cystic fibrosis
    • 10.2165/11316240-000000000-00000
    • Van Westreenen M, Tiddens HAWM. New antimicrobial strategies in cystic fibrosis. Pediatr Drugs. 2010;12(6):343-52.
    • (2010) Pediatr Drugs. , vol.12 , Issue.6 , pp. 343-352
    • Van Westreenen, M.1    Tiddens, H.2
  • 47
    • 77953328174 scopus 로고    scopus 로고
    • Emerging therapies in cystic fibrosis
    • 20530065 10.1177/1753465810371107 1:CAS:528:DC%2BC3cXhs1aktbrJ
    • Anderson P. Emerging therapies in cystic fibrosis. Ther Adv Respir Dis. 2010;4(3):177-85.
    • (2010) Ther Adv Respir Dis. , vol.4 , Issue.3 , pp. 177-185
    • Anderson, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.