-
1
-
-
80053377162
-
TM: A novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis
-
21955231 10.1586/ers.11.56 1:CAS:528:DC%2BC3MXht1Clur3N
-
TM: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis. Expert Rev Respir Med. 2011;5(5):609-22.
-
(2011)
Expert Rev Respir Med.
, vol.5
, Issue.5
, pp. 609-622
-
-
Parkins, M.D.1
Elborn, J.S.2
-
2
-
-
84889073216
-
Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: A review
-
10.2147/MDER.S16360 22915944
-
VanDevanter DR, Geller DE. Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: a review. Med Devices (Auckl). 2011. doi: 10.2147/MDER.S16360.
-
(2011)
Med Devices (Auckl).
-
-
Vandevanter, D.R.1
Geller, D.E.2
-
3
-
-
51349100398
-
The prevalence of cystic fibrosis in the European Union
-
18442953 10.1016/j.jcf.2008.03.007
-
Farrell PM. The prevalence of cystic fibrosis in the European Union. J Cyst Fibros. 2008;7:450-3.
-
(2008)
J Cyst Fibros.
, vol.7
, pp. 450-453
-
-
Farrell, P.M.1
-
4
-
-
79953262396
-
Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
-
21463524 10.1186/1741-7015-9-32
-
Høiby N. Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med. 2011;9:32.
-
(2011)
BMC Med.
, vol.9
, pp. 32
-
-
Høiby, N.1
-
5
-
-
36248953255
-
Cystic fibrosis pulmonary guidelines: Chronic medications for maintenance of lung health
-
17761616 10.1164/rccm.200705-664OC 1:CAS:528:DC%2BD2sXhsVekt77N
-
Flume PA, O'Sullivan BP, Robinson KA, et al. Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med. 2007;176(10):957-69.
-
(2007)
Am J Respir Crit Care Med.
, vol.176
, Issue.10
, pp. 957-969
-
-
Flume, P.A.1
O'Sullivan, B.P.2
Robinson, K.A.3
-
6
-
-
66849142486
-
Aerosol antibiotics in cystic fibrosis
-
19393109 10.4187/aarc0537
-
Geller DE. Aerosol antibiotics in cystic fibrosis. Respir Care. 2009;54(5):658-69.
-
(2009)
Respir Care.
, vol.54
, Issue.5
, pp. 658-669
-
-
Geller, D.E.1
-
7
-
-
0142043977
-
Pathophysiology and management of pulmonary infections in cystic fibrosis
-
14555458 10.1164/rccm.200304-505SO
-
Gibson RL, Burns JL, Ramsey BW. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med. 2003;168(8):918-51.
-
(2003)
Am J Respir Crit Care Med.
, vol.168
, Issue.8
, pp. 918-951
-
-
Gibson, R.L.1
Burns, J.L.2
Ramsey, B.W.3
-
8
-
-
0242609342
-
®): A review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis
-
14609360 10.2165/00003495-200363220-00015 1:CAS:528:DC%2BD3sXpvFShsLg%3D
-
®): a review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis. Drugs. 2003;63:2501-20.
-
(2003)
Drugs.
, vol.63
, pp. 2501-2520
-
-
Cheer, S.M.1
Waugh, J.2
Noble, S.3
-
9
-
-
60449117029
-
High treatment burden in adults with cystic fibrosis: Challenges to disease self management
-
18952504 10.1016/j.jcf.2008.09.007
-
Sawicki GS, Sellers DE, Robinson WM, et al. High treatment burden in adults with cystic fibrosis: challenges to disease self management. J Cyst Fibros. 2009;8(2):91-6.
-
(2009)
J Cyst Fibros.
, vol.8
, Issue.2
, pp. 91-96
-
-
Sawicki, G.S.1
Sellers, D.E.2
Robinson, W.M.3
-
10
-
-
85081791022
-
-
European Medicines Agency Summary of product characteristics Accessed 17 Oct 2013
-
European Medicines Agency. TOBI Podhaler 28 mg inhalation powder, hard capsules. Summary of product characteristics. 2011. http://www.ema.europa.eu/ docs/en-GB/document-library/EPAR-Product-Information/human/002155/WC500110921. pdf. Accessed 17 Oct 2013.
-
(2011)
TOBI Podhaler 28 Mg Inhalation Powder, Hard Capsules
-
-
-
11
-
-
34547464547
-
-
Novartis Pharmaceuticals Corporation. TOBI PODHALER (Tobramycin Inhalation Powder) Accessed 17 Oct 2013
-
Novartis Pharmaceuticals Corporation. TOBI PODHALER (Tobramycin Inhalation Powder). Full prescribing information. 2013. http://www.pharma.us. novartis.com/cs/www.pharma.us.novartis.com/product/pi/pdf/tobipodhaler.pdf. Accessed 17 Oct 2013.
-
(2013)
Full Prescribing Information
-
-
-
12
-
-
70449687936
-
Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: A review
-
19747887 10.1016/j.jcf.2009.08.004 1:CAS:528:DC%2BD1MXhsVGmsLnN
-
Ratjen F, Brockhaus F, Angyalosi G. Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: a review. J Cyst Fibros. 2009;8(6):361-9.
-
(2009)
J Cyst Fibros.
, vol.8
, Issue.6
, pp. 361-369
-
-
Ratjen, F.1
Brockhaus, F.2
Angyalosi, G.3
-
13
-
-
84862487763
-
Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis
-
22445849 10.1016/j.jcf.2012.02.005
-
Ren CL, Konstan MW, Yegin A, et al. Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis. J Cyst Fibros. 2012;11(4):293-9.
-
(2012)
J Cyst Fibros.
, vol.11
, Issue.4
, pp. 293-299
-
-
Ren, C.L.1
Konstan, M.W.2
Yegin, A.3
-
14
-
-
0033531143
-
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis
-
9878641 10.1056/NEJM199901073400104 1:CAS:528:DyaK1MXltFeltw%3D%3D
-
Ramsey BW, Pepe MS, Quan JM, et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. N Engl J Med. 1999;340:23-30.
-
(1999)
N Engl J Med.
, vol.340
, pp. 23-30
-
-
Ramsey, B.W.1
Pepe, M.S.2
Quan, J.M.3
-
15
-
-
69549135253
-
Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus
-
19559658 10.1016/j.jcf.2009.04.005 1:CAS:528:DC%2BD1MXhtV2rsL7I
-
Heijerman H, Westerman E, Conway S, et al. Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: a European consensus. J Cyst Fibros. 2009;8(5):295-315.
-
(2009)
J Cyst Fibros.
, vol.8
, Issue.5
, pp. 295-315
-
-
Heijerman, H.1
Westerman, E.2
Conway, S.3
-
17
-
-
0038826781
-
Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers
-
12853545 10.1378/chest.124.1.360 1:CAS:528:DC%2BD3sXmsFClt7s%3D
-
Newhouse MT, Hirst PH, Duddu SP, et al. Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers. Chest. 2003;124(1):360-6.
-
(2003)
Chest.
, vol.124
, Issue.1
, pp. 360-366
-
-
Newhouse, M.T.1
Hirst, P.H.2
Duddu, S.P.3
-
18
-
-
33846068813
-
Effect of dry powder inhaler resistance on the inspiratory flow rates and volumes of cystic fibrosis patients of six years and older
-
17196074 10.1089/jam.2006.19.456 1:CAS:528:DC%2BD28XhtlGqtLzJ
-
Tiddens HA, Geller DE, Challoner P, et al. Effect of dry powder inhaler resistance on the inspiratory flow rates and volumes of cystic fibrosis patients of six years and older. J Aerosol Med. 2006;19(4):456-65.
-
(2006)
J Aerosol Med.
, vol.19
, Issue.4
, pp. 456-465
-
-
Tiddens, H.A.1
Geller, D.E.2
Challoner, P.3
-
19
-
-
84887747253
-
Inspiratory flow characteristics of the T-326 dry powder inhaler (DPI) in CF patients [abstract no. 72]
-
10.1016/S1569-1993(13)60214-3
-
Geller D, Ament B, Heuerding S, et al. Inspiratory flow characteristics of the T-326 dry powder inhaler (DPI) in CF patients [abstract no. 72]. J Cyst Fibros. 2013;12(Suppl):S66.
-
(2013)
J Cyst Fibros.
, vol.12
, Issue.SUPPL.
, pp. 66
-
-
Geller, D.1
Ament, B.2
Heuerding, S.3
-
21
-
-
34247193128
-
Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
-
17352404 10.1002/ppul.20594
-
Geller DE, Konstan MW, Smith J, et al. Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediatr Pulmonol. 2007;42(4):307-13.
-
(2007)
Pediatr Pulmonol.
, vol.42
, Issue.4
, pp. 307-313
-
-
Geller, D.E.1
Konstan, M.W.2
Smith, J.3
-
22
-
-
84923149470
-
Reduced administration time for inhaled tobramycin in cystic fibrosis patients: Results from the EAGER trial [abstract]
-
17-19 Oct 2013; Salt Lake City
-
Nasr S, Nick J, Ezzet N, et al. Reduced administration time for inhaled tobramycin in cystic fibrosis patients: results from the EAGER trial [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
-
27th Annual North American Cystic Fibrosis Conference
-
-
Nasr, S.1
Nick, J.2
Ezzet, N.3
-
23
-
-
84876034477
-
Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin
-
22620494 10.1089/jamp.2011.0942 1:CAS:528:DC%2BC3sXlsV2ltLs%3D
-
Ruddy J, Emerson J, Moss R, et al. Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin. J Aerosol Med Pulm Drug Deliv. 2013;26(2):69-75.
-
(2013)
J Aerosol Med Pulm Drug Deliv.
, vol.26
, Issue.2
, pp. 69-75
-
-
Ruddy, J.1
Emerson, J.2
Moss, R.3
-
24
-
-
84880473914
-
Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: The randomized EDIT trial
-
23672633 10.1185/03007995.2013.805122 1:CAS:528:DC%2BC3sXhtFeqsLzI
-
Galeva I, Konstan MW, Higgins M, et al. Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: the randomized EDIT trial. Curr Med Res Opin. 2013;29(8):947-56.
-
(2013)
Curr Med Res Opin.
, vol.29
, Issue.8
, pp. 947-956
-
-
Galeva, I.1
Konstan, M.W.2
Higgins, M.3
-
25
-
-
79951840468
-
Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: The EVOLVE trial
-
20963831 10.1002/ppul.21356
-
Konstan MW, Geller DE, Minic P, et al. Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: The EVOLVE trial. Pediatr Pulmonol. 2011;46(3):230-8.
-
(2011)
Pediatr Pulmonol.
, vol.46
, Issue.3
, pp. 230-238
-
-
Konstan, M.W.1
Geller, D.E.2
Minic, P.3
-
26
-
-
78651412529
-
Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial
-
21075062 10.1016/j.jcf.2010.10.003 1:CAS:528:DC%2BC3MXntVGltw%3D%3D
-
Konstan MW, Flume PA, Kappler M, et al. Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial. J Cyst Fibros. 2011;10(1):54-61.
-
(2011)
J Cyst Fibros.
, vol.10
, Issue.1
, pp. 54-61
-
-
Konstan, M.W.1
Flume, P.A.2
Kappler, M.3
-
27
-
-
84923149467
-
Long-term safety and efficacy of tobramycin inhalation powder in cystic fibrosis patients with P. Aeruginosa: The EDIT trial and its two open-label extension studies [abstract]
-
17-19 Oct 2013; Salt Lake City
-
Konstan MW, Flume PA, Wan R, et al. Long-term safety and efficacy of tobramycin inhalation powder in cystic fibrosis patients with P. aeruginosa: the EDIT trial and its two open-label extension studies [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
-
27th Annual North American Cystic Fibrosis Conference
-
-
Konstan, M.W.1
Flume, P.A.2
Wan, R.3
-
28
-
-
84869087512
-
Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis
-
22583743 10.1016/j.jcf.2012.04.007
-
Regnault A, Balp M-M, Kulich K, et al. Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis. J Cyst Fibros. 2012;11(6):494-501.
-
(2012)
J Cyst Fibros.
, vol.11
, Issue.6
, pp. 494-501
-
-
Regnault, A.1
Balp, M.-M.2
Kulich, K.3
-
29
-
-
85081794573
-
Association of treatment satisfaction and compliance of cystic fibrosis (CF) patients using inhaled tobramycin treatment in the EAGER study
-
8-11 June 2011, Hamburg
-
Regnault A, Bal MM, Kulich K, et al. Association of treatment satisfaction and compliance of cystic fibrosis (CF) patients using inhaled tobramycin treatment in the EAGER study. 34th European Cystic Fibrosis Conference; 8-11 June 2011, Hamburg.
-
34th European Cystic Fibrosis Conference
-
-
Regnault, A.1
Bal, M.M.2
Kulich, K.3
-
30
-
-
84888992940
-
Tobramycin inhalation powder in cystic fibrosis patients: Response by age group
-
10.4187/respcare.02264 23983274
-
Geller DE, Nasr SZ, Piggott S, et al. Tobramycin inhalation powder in cystic fibrosis patients: response by age group. Respir Care. 2013. doi: 10.4187/respcare.02264.
-
(2013)
Respir Care.
-
-
Geller, D.E.1
Nasr, S.Z.2
Piggott, S.3
-
31
-
-
84889046027
-
Improved tolerability, adherence and reduced intravenous (IV) antibiotic usage in CF patients receiving inhaled versus nebulised antibiotic prophylaxis. A real world comparison of tobramycin inhaled powder (TIP) and tobramycin inhaled solution (TIS) [abstract no. 74]
-
10.1016/S1569-1993(13)60216-7
-
Harrison MJ, McCarthy C, Fleming C, et al. Improved tolerability, adherence and reduced intravenous (IV) antibiotic usage in CF patients receiving inhaled versus nebulised antibiotic prophylaxis. A real world comparison of tobramycin inhaled powder (TIP) and tobramycin inhaled solution (TIS) [abstract no. 74]. J Cyst Fibros. 2013;12(Suppl):S67.
-
(2013)
J Cyst Fibros.
, vol.12
, Issue.SUPPL.
, pp. 67
-
-
Harrison, M.J.1
McCarthy, C.2
Fleming, C.3
-
32
-
-
84889020779
-
Comparison of pharmacy prescription refill frequency in CF adults before and after switching from tobramycin inhalation solution (TIS) to TOBI Podhaler: 'Real world' evidence of improved adherence [abstract no. 68]
-
10.1016/S1569-1993(13)60210-6
-
Nash EF, Ahitan B, Brown CJ, et al. Comparison of pharmacy prescription refill frequency in CF adults before and after switching from tobramycin inhalation solution (TIS) to TOBI Podhaler: 'real world' evidence of improved adherence [abstract no. 68]. J Cyst Fibros. 2013;12(Suppl):S65.
-
(2013)
J Cyst Fibros.
, vol.12
, Issue.SUPPL.
, pp. 65
-
-
Nash, E.F.1
Ahitan, B.2
Brown, C.J.3
-
34
-
-
4544330253
-
-
Cystic Fibrosis Foundation Accessed 21 Aug 2013
-
Cystic Fibrosis Foundation. Patient registry: annual data report. 2011. http://www.cff.org/LivingWithCF/QualityImprovement/PatientRegistryReport/. Accessed 21 Aug 2013.
-
(2011)
Patient Registry: Annual Data Report
-
-
-
35
-
-
3343023861
-
Early intervention and prevention of lung disease in cystic fibrosis: A European consensus
-
15463891 10.1016/j.jcf.2004.03.008
-
Doring G, Hoiby N. Early intervention and prevention of lung disease in cystic fibrosis: a European consensus. J Cyst Fibros. 2004;3:67-91.
-
(2004)
J Cyst Fibros.
, vol.3
, pp. 67-91
-
-
Doring, G.1
Hoiby, N.2
-
36
-
-
84866172783
-
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis
-
22717535 10.1016/j.jcf.2012.03.010 1:CAS:528:DC%2BC38XhtlOjurrK
-
Littlewood KJ, Higashi K, Jansen JP, et al. A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis. J Cyst Fibros. 2012;11(5):419-26.
-
(2012)
J Cyst Fibros.
, vol.11
, Issue.5
, pp. 419-426
-
-
Littlewood, K.J.1
Higashi, K.2
Jansen, J.P.3
-
37
-
-
84155165377
-
Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution
-
21815282 10.1002/ppul.21521
-
Sawicki GS, Signorovitch JE, Zhang J, et al. Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution. Pediatr Pulmonol. 2012;47(1):44-52.
-
(2012)
Pediatr Pulmonol.
, vol.47
, Issue.1
, pp. 44-52
-
-
Sawicki, G.S.1
Signorovitch, J.E.2
Zhang, J.3
-
38
-
-
4544269731
-
Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease
-
15334509 10.1002/ppul.20097
-
Murphy TD, Anbar RD, Lester LA, et al. Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease. Pediatr Pulmonol. 2004;38(4):314-20.
-
(2004)
Pediatr Pulmonol.
, vol.38
, Issue.4
, pp. 314-320
-
-
Murphy, T.D.1
Anbar, R.D.2
Lester, L.A.3
-
39
-
-
0036157901
-
Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis
-
11796432 10.1378/chest.121.1.55 1:CAS:528:DC%2BD38Xht1yltbs%3D
-
Moss RB. Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis. Chest. 2002;121(1):55-63.
-
(2002)
Chest.
, vol.121
, Issue.1
, pp. 55-63
-
-
Moss, R.B.1
-
41
-
-
85081799491
-
Convenience and stated adherence for antibiotic treatment of cystic-fibrosis pseudomonas infections [abstract]
-
17-19 Oct 2013; Salt Lake City
-
Mohamed AF, Reed Johnson FR, Balp MM, et al. Convenience and stated adherence for antibiotic treatment of cystic-fibrosis pseudomonas infections [abstract]. 27th Annual North American Cystic Fibrosis Conference; 17-19 Oct 2013; Salt Lake City.
-
27th Annual North American Cystic Fibrosis Conference
-
-
Mohamed, A.F.1
Reed Johnson, F.R.2
Balp, M.M.3
-
42
-
-
84864283580
-
In vitro prevention of Pseudomonas aeruginosa early biofilm formation with antibiotics used in cystic fibrosis patients
-
22727530 10.1016/j.ijantimicag.2012.04.006 1:CAS:528:DC%2BC38XptVKls7g%3D
-
Fernandez-Olmos A, Garcia-Castillo M, Maiz L, et al. In vitro prevention of Pseudomonas aeruginosa early biofilm formation with antibiotics used in cystic fibrosis patients. Int J Antimicrob Agents. 2012;40(2):173-6.
-
(2012)
Int J Antimicrob Agents.
, vol.40
, Issue.2
, pp. 173-176
-
-
Fernandez-Olmos, A.1
Garcia-Castillo, M.2
Maiz, L.3
-
43
-
-
84870768231
-
Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colinized by P. Aeruginosa
-
Schelstraete P, Haerynck F, Van daele S, et al. Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colinized by P. aeruginosa. J Cyst Fibros. 2013;12:1-8.
-
(2013)
J Cyst Fibros
, vol.12
, pp. 1-8
-
-
Schelstraete, P.1
Haerynck, F.2
Van Daele, S.3
-
44
-
-
84855279786
-
Aerosolized antibiotic therapy for chronic cystic fibrosis airway infections: Continuous or intermittent?
-
10.1016/S0954-6111(11)70022-1
-
Lo D, VanDevanter DR, Flume P, et al. Aerosolized antibiotic therapy for chronic cystic fibrosis airway infections: continuous or intermittent? Resp Med. 2011;105(Suppl 2):S9-17.
-
(2011)
Resp Med.
, vol.105
, Issue.SUPPL.
-
-
Lo, D.1
Vandevanter, D.R.2
Flume, P.3
-
45
-
-
70349096824
-
Emerging treatments in cystic fibrosis
-
19747007 10.2165/11318500-000000000-00000 1:CAS:528:DC%2BD1MXhtlOrsLbO
-
Jones AM, Helm JM. Emerging treatments in cystic fibrosis. Drugs. 2009;69(14):1903-10.
-
(2009)
Drugs.
, vol.69
, Issue.14
, pp. 1903-1910
-
-
Jones, A.M.1
Helm, J.M.2
-
46
-
-
78049402553
-
New antimicrobial strategies in cystic fibrosis
-
10.2165/11316240-000000000-00000
-
Van Westreenen M, Tiddens HAWM. New antimicrobial strategies in cystic fibrosis. Pediatr Drugs. 2010;12(6):343-52.
-
(2010)
Pediatr Drugs.
, vol.12
, Issue.6
, pp. 343-352
-
-
Van Westreenen, M.1
Tiddens, H.2
-
47
-
-
77953328174
-
Emerging therapies in cystic fibrosis
-
20530065 10.1177/1753465810371107 1:CAS:528:DC%2BC3cXhs1aktbrJ
-
Anderson P. Emerging therapies in cystic fibrosis. Ther Adv Respir Dis. 2010;4(3):177-85.
-
(2010)
Ther Adv Respir Dis.
, vol.4
, Issue.3
, pp. 177-185
-
-
Anderson, P.1
|