Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments

Journal of Leukocyte Biology

Volumn 94, Issue 6, 2013, Pages 1285-1292

  Marwick, John A ^a   Dorward, David A ^a   Lucas, Christopher D ^a   Jones, Katie O ^a   Sheldrake, Tara A ^a   Fox, Sarah ^a   Ward, Carol ^a,b   Murray, Joanna ^a   Brittan, Mairi ^a   Hirani, Nik ^a   Duffin, Rodger ^a   Dransfield, Ian ^a,c   Haslett, Christopher ^a   Rossi, Adriano G ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CXR Biosciences Ltd   (United Kingdom)

Author keywords

Apoptosis; Hypoxia; Inflammation; Steroids

Indexed keywords

BECLOMETASONE; BUDESONIDE; DEXAMETHASONE; GLUCOCORTICOID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; METHYLPREDNISOLONE;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CELL SURVIVAL; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATION; LEUKOCYTE FUNCTION; MACROPHAGE; NEUTROPHIL; NORMAL HUMAN; OXYGEN CONCENTRATION; OXYGEN TENSION; PRIORITY JOURNAL; RESPIRATORY BURST; RESPIRATORY TRACT INFLAMMATION;

APOPTOSIS; HYPOXIA; INFLAMMATION; STEROIDS;

APOPTOSIS; CELL SURVIVAL; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; NEUTROPHILS; OXYGEN;

EID: 84888786090     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0912462     Document Type: Article

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