메뉴 건너뛰기




Volumn 14, Issue 12, 2013, Pages 1601-1610

Chronic inflammatory pain prevents tolerance to the antinociceptive effect of morphine microinjected into the ventrolateral periaqueductal gray of the rat

Author keywords

analgesia; inflammatory pain; morphine tolerance; Opioid; periaqueductal gray

Indexed keywords

MORPHINE; MORPHINE SULFATE; SODIUM CHLORIDE;

EID: 84888646663     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.08.003     Document Type: Article
Times cited : (13)

References (59)
  • 1
    • 0019518850 scopus 로고
    • Apparent lack of tolerance in the formalin test suggests different mechanisms for morphine analgesia in different types of pain
    • DOI 10.1016/0091-3057(81)90222-7
    • F.V. Abbott, K.B. Franklin, R.J. Ludwick, and R. Melzack Apparent lack of tolerance in the formalin test suggests different mechanisms for morphine analgesia in different types of pain Pharmacol Biochem Behav 15 1981 637 640 (Pubitemid 11015569)
    • (1981) Pharmacology Biochemistry and Behavior , vol.15 , Issue.4 , pp. 637-640
    • Abbott, F.V.1    Franklin, K.B.J.2    Ludwick, R.J.3    Melzack, R.4
  • 2
    • 30644458052 scopus 로고    scopus 로고
    • Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine
    • E.E. Bagley, B.C. Chieng, M.J. Christie, and M. Connor Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine Br J Pharmacol 146 2005 68 76
    • (2005) Br J Pharmacol , vol.146 , pp. 68-76
    • Bagley, E.E.1    Chieng, B.C.2    Christie, M.J.3    Connor, M.4
  • 3
    • 84864431498 scopus 로고    scopus 로고
    • Differential development of antinociceptive tolerance to morphine and fentanyl is not linked to efficacy in the ventrolateral periaqueductal gray of the rat
    • E.N. Bobeck, R.A. Haseman, D. Hong, S.L. Ingram, and M.M. Morgan Differential development of antinociceptive tolerance to morphine and fentanyl is not linked to efficacy in the ventrolateral periaqueductal gray of the rat J Pain 13 2012 799 807
    • (2012) J Pain , vol.13 , pp. 799-807
    • Bobeck, E.N.1    Haseman, R.A.2    Hong, D.3    Ingram, S.L.4    Morgan, M.M.5
  • 4
    • 70449632308 scopus 로고    scopus 로고
    • Drug dependent sex-differences in periaqueducatal gray mediated antinociception in the rat
    • E.N. Bobeck, A.L. McNeal, and M.M. Morgan Drug dependent sex-differences in periaqueducatal gray mediated antinociception in the rat Pain 147 2009 210 216
    • (2009) Pain , vol.147 , pp. 210-216
    • Bobeck, E.N.1    McNeal, A.L.2    Morgan, M.M.3
  • 5
    • 0023133277 scopus 로고
    • Parallel clinical and behavioural studies of adjuvant-induced arthritis in the rat: Possible relationship with 'chronic pain'
    • DOI 10.1016/0166-4328(87)90032-5
    • B. Calvino, M.O. Crepon-Bernard, and D. Le Bars Parallel clinical and behavioural studies of adjuvant-induced arthritis in the rat: Possible relationship with "chronic pain" Behav Brain Res 24 1987 11 29 (Pubitemid 17056350)
    • (1987) Behavioural Brain Research , vol.24 , Issue.1 , pp. 11-29
    • Calvino, B.1    Crepon-Bernard, M.-O.2    Le Bars, D.3
  • 6
    • 70350227157 scopus 로고    scopus 로고
    • Early methylphenidate exposure enhances morphine antinociception and tolerance in adult rats
    • M.C. Cyr, and M.M. Morgan Early methylphenidate exposure enhances morphine antinociception and tolerance in adult rats Neuropharmacology 57 2009 673 677
    • (2009) Neuropharmacology , vol.57 , pp. 673-677
    • Cyr, M.C.1    Morgan, M.M.2
  • 7
    • 84884478870 scopus 로고    scopus 로고
    • Persistent peripheral inflammation attenuates morphine-induced periaqueductal gray glial cell activation and analgesic tolerance in the male rat
    • L.N. Eidson, and A.Z. Murphy Persistent peripheral inflammation attenuates morphine-induced periaqueductal gray glial cell activation and analgesic tolerance in the male rat J Pain 14 2013 393 404
    • (2013) J Pain , vol.14 , pp. 393-404
    • Eidson, L.N.1    Murphy, A.Z.2
  • 8
    • 33748799410 scopus 로고    scopus 로고
    • Efficacy of mu-opioid agonists in the treatment of evoked neuropathic pain: Systematic review of randomized controlled trials
    • DOI 10.1016/j.ejpain.2005.10.007, PII S109038010500159X
    • E. Eisenberg, E.D. McNicol, and D.B. Carr Efficacy of mu-opioid agonists in the treatment of evoked neuropathic pain: Systematic review of randomized controlled trials Eur J Pain 10 2006 667 676 (Pubitemid 44416280)
    • (2006) European Journal of Pain , vol.10 , Issue.8 , pp. 667-676
    • Eisenberg, E.1    McNicol, E.D.2    Carr, D.B.3
  • 9
    • 77956511264 scopus 로고    scopus 로고
    • A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain
    • J.T. Farrar, J. Messina, F. Xie, and R.K. Portenoy A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain Pain Med 11 2010 1313 1327
    • (2010) Pain Med , vol.11 , pp. 1313-1327
    • Farrar, J.T.1    Messina, J.2    Xie, F.3    Portenoy, R.K.4
  • 11
    • 78649542294 scopus 로고    scopus 로고
    • Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons
    • L.W. Fyfe, D.R. Cleary, T.A. Macey, M.M. Morgan, and S.L. Ingram Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons J Pharmacol Exp Ther 335 2010 674 680
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 674-680
    • Fyfe, L.W.1    Cleary, D.R.2    Macey, T.A.3    Morgan, M.M.4    Ingram, S.L.5
  • 12
    • 79551597726 scopus 로고    scopus 로고
    • The influence of non-nociceptive factors on hot-plate latency in rats
    • A. Gunn, E.N. Bobeck, C. Weber, and M.M. Morgan The influence of non-nociceptive factors on hot-plate latency in rats J Pain 12 2011 222 227
    • (2011) J Pain , vol.12 , pp. 222-227
    • Gunn, A.1    Bobeck, E.N.2    Weber, C.3    Morgan, M.M.4
  • 13
    • 30644477580 scopus 로고    scopus 로고
    • Supraspinal brain-derived neurotrophic factor signaling: A novel mechanism for descending pain facilitation
    • DOI 10.1523/JNEUROSCI.3686-05.2006
    • W. Guo, M.T. Robbins, F. Wei, S. Zou, R. Dubner, and K. Ren Supraspinal brain-derived neurotrophic factor signaling: A novel mechanism for descending pain facilitation J Neurosci 26 2006 126 137 (Pubitemid 43089525)
    • (2006) Journal of Neuroscience , vol.26 , Issue.1 , pp. 126-137
    • Guo, W.1    Robbins, M.T.2    Wei, F.3    Zou, S.4    Dubner, R.5    Ren, K.6
  • 14
    • 0029015804 scopus 로고
    • Does chronic nociceptive stimulation alter the development of morphine tolerance?
    • H.B. Gutstein, K.A. Trujillo, and H. Akil Does chronic nociceptive stimulation alter the development of morphine tolerance? Brain Res 680 1995 173 179
    • (1995) Brain Res , vol.680 , pp. 173-179
    • Gutstein, H.B.1    Trujillo, K.A.2    Akil, H.3
  • 15
    • 0018090614 scopus 로고
    • Morphine tolerance: Is there evidence for a conditioning model?
    • R.L. Hayes, and D.J. Mayer Morphine tolerance: Is there evidence for a conditioning model? Science 200 1978 343 345 (Pubitemid 8326073)
    • (1978) Science , vol.200 , Issue.4339 , pp. 343-345
    • Hayes, R.L.1    Mayer, D.J.2
  • 16
    • 0037169345 scopus 로고    scopus 로고
    • Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization
    • DOI 10.1016/S0092-8674(02)00613-X
    • L. He, J. Fong, M. von Zastrow, and J.L. Whistler Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization Cell 108 2002 271 282 (Pubitemid 34161146)
    • (2002) Cell , vol.108 , Issue.2 , pp. 271-282
    • He, L.1    Fong, J.2    Von Zastrow, M.3    Whistler, J.L.4
  • 17
    • 4744351526 scopus 로고    scopus 로고
    • Dipyrone potentiates morphine-induced antinociception in dipyrone-treated and morphine-tolerant rats
    • DOI 10.1016/j.ejphar.2004.08.032, PII S0014299904009446
    • G.P. Hernandez-Delgadillo, and S.L. Cruz Dipyrone potentiates morphine-induced antinociception in dipyrone-treated and morphine-tolerant rats Eur J Pharmacol 502 2004 67 73 (Pubitemid 39311366)
    • (2004) European Journal of Pharmacology , vol.502 , Issue.1-2 , pp. 67-73
    • Hernandez-Delgadillo, G.P.1    Cruz, S.L.2
  • 20
    • 33847017326 scopus 로고    scopus 로고
    • Behavioral and electrophysiological evidence for opioid tolerance in adolescent rats
    • S.L. Ingram, E.N. Fossum, and M.M. Morgan Behavioral and electrophysiological evidence for opioid tolerance in adolescent rats Neuropsychopharmacology 32 2007 600 606
    • (2007) Neuropsychopharmacology , vol.32 , pp. 600-606
    • Ingram, S.L.1    Fossum, E.N.2    Morgan, M.M.3
  • 21
    • 49549106922 scopus 로고    scopus 로고
    • Tolerance to repeated morphine administration is associated with increased potency of opioid agonists
    • S.L. Ingram, T.A. Macey, E.N. Fossum, and M.M. Morgan Tolerance to repeated morphine administration is associated with increased potency of opioid agonists Neuropsychopharmacology 33 2008 2494 2504
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2494-2504
    • Ingram, S.L.1    Macey, T.A.2    Fossum, E.N.3    Morgan, M.M.4
  • 22
    • 0032535012 scopus 로고    scopus 로고
    • Enhanced opioid efficacy in opioid dependence is caused by an altered signal transduction pathway
    • S.L. Ingram, C.W. Vaughan, E.E. Bagley, M. Connor, and M.J. Christie Enhanced opioid efficacy in opioid dependence is caused by an altered signal transduction pathway J Neurosci 18 1998 10269 10276 (Pubitemid 29016546)
    • (1998) Journal of Neuroscience , vol.18 , Issue.24 , pp. 10269-10276
    • Ingram, S.L.1    Vaughan, C.W.2    Bagley, E.E.3    Connor, M.4    Christie, M.J.5
  • 23
    • 0017230095 scopus 로고
    • Morphine-induced rotation in naive, nonlesioned rats
    • Y.F. Jacquet, M. Carol, and I.S. Russell Morphine-induced rotation in naive, nonlesioned rats Science 192 1976 261 263
    • (1976) Science , vol.192 , pp. 261-263
    • Jacquet, Y.F.1    Carol, M.2    Russell, I.S.3
  • 24
    • 0016278017 scopus 로고
    • Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat
    • Y.F. Jacquet, and A. Lajtha Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat Science 185 1974 1055 1057
    • (1974) Science , vol.185 , pp. 1055-1057
    • Jacquet, Y.F.1    Lajtha, A.2
  • 25
    • 26844505756 scopus 로고    scopus 로고
    • Changes in G proteins genes expression in rat lumbar spinal cord support the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia
    • DOI 10.1016/j.neures.2005.06.020, PII S0168010205001896
    • M. Javan, A. Ahmadiani, F. Motamadi, and B. Kazemi Changes in G proteins genes expression in rat lumbar spinal cord support the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia Neurosci Res 53 2005 250 256 (Pubitemid 41463778)
    • (2005) Neuroscience Research , vol.53 , Issue.3 , pp. 250-256
    • Javan, M.1    Ahmadiani, A.2    Motamadi, F.3    Kazemi, B.4
  • 26
    • 0023034602 scopus 로고
    • Repeated low doses of morphine induce a rapid tolerance in arthritic rats but a potentiation of opiate analgesia in normal animals
    • DOI 10.1016/0006-8993(86)90047-8
    • V. Kayser, A. Neil, and G. Guilbaud Repeated low doses of morphine induce a rapid tolerance in arthritic rats but a potentiation of opiate analgesia in normal animals Brain Res 383 1986 392 396 (Pubitemid 17180004)
    • (1986) Brain Research , vol.383 , Issue.1-2 , pp. 392-396
    • Kayser, V.1    Neil, A.2    Guilbaud, G.3
  • 27
    • 77950370960 scopus 로고    scopus 로고
    • Measuring persistent temporomandibular joint nociception in rats and two mice strains
    • P.R. Kramer, C.A. Kerins, E. Schneiderman, and L.L. Bellinger Measuring persistent temporomandibular joint nociception in rats and two mice strains Physiol Behav 99 2010 669 678
    • (2010) Physiol Behav , vol.99 , pp. 669-678
    • Kramer, P.R.1    Kerins, C.A.2    Schneiderman, E.3    Bellinger, L.L.4
  • 28
    • 20444393992 scopus 로고    scopus 로고
    • Antinociceptive tolerance to morphine from repeated nociceptive testing in the rat
    • DOI 10.1016/j.brainres.2005.04.001, PII S0006899305005172
    • D.A. Lane, and M.M. Morgan Antinociceptive tolerance to morphine from repeated nociceptive testing in the rat Brain Res 1047 2005 65 71 (Pubitemid 40805031)
    • (2005) Brain Research , vol.1047 , Issue.1 , pp. 65-71
    • Lane, D.A.1    Morgan, M.M.2
  • 29
    • 1642421274 scopus 로고    scopus 로고
    • Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray
    • DOI 10.1016/j.neuroscience.2004.01.023, PII S0306452204000624
    • D.A. Lane, V. Tortorici, and M.M. Morgan Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray Neuroscience 125 2004 63 69 (Pubitemid 38402160)
    • (2004) Neuroscience , vol.125 , Issue.1 , pp. 63-69
    • Lane, D.A.1    Tortorici, V.2    Morgan, M.M.3
  • 31
    • 33644992364 scopus 로고    scopus 로고
    • Chronic pain and genetic background interact and influence opioid analgesia, tolerance, and physical dependence
    • D.Y. Liang, T. Guo, G. Liao, W.S. Kingery, G. Peltz, and J.D. Clark Chronic pain and genetic background interact and influence opioid analgesia, tolerance, and physical dependence Pain 121 2006 232 240
    • (2006) Pain , vol.121 , pp. 232-240
    • Liang, D.Y.1    Guo, T.2    Liao, G.3    Kingery, W.S.4    Peltz, G.5    Clark, J.D.6
  • 32
    • 40949133434 scopus 로고    scopus 로고
    • Sexually dimorphic activation of the periaqueductal gray-rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat
    • DOI 10.1111/j.1460-9568.2008.06100.x
    • D.R. Loyd, M.M. Morgan, and A.Z. Murphy Sexually dimorphic activation of the periaqueductal gray-rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat Eur J Neurosci 27 2008 1517 1524 (Pubitemid 351406258)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.6 , pp. 1517-1524
    • Loyd, D.R.1    Morgan, M.M.2    Murphy, A.Z.3
  • 33
    • 33645985808 scopus 로고    scopus 로고
    • Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: A potential circuit mediating the sexually dimorphic actions of morphine
    • D.R. Loyd, and A.Z. Murphy Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: A potential circuit mediating the sexually dimorphic actions of morphine J Comp Neurol 496 2006 723 738
    • (2006) J Comp Neurol , vol.496 , pp. 723-738
    • Loyd, D.R.1    Murphy, A.Z.2
  • 34
    • 58149389441 scopus 로고    scopus 로고
    • Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia
    • D.R. Loyd, X. Wang, and A.Z. Murphy Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia J Neurosci 28 2008 14007 14017
    • (2008) J Neurosci , vol.28 , pp. 14007-14017
    • Loyd, D.R.1    Wang, X.2    Murphy, A.Z.3
  • 35
    • 70350440311 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat
    • T.A. Macey, E.N. Bobeck, D.M. Hegarty, S.A. Aicher, S.L. Ingram, and M.M. Morgan Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat J Pharmacol Exp Ther 331 2009 412 418
    • (2009) J Pharmacol Exp Ther , vol.331 , pp. 412-418
    • Macey, T.A.1    Bobeck, E.N.2    Hegarty, D.M.3    Aicher, S.A.4    Ingram, S.L.5    Morgan, M.M.6
  • 36
    • 34249696508 scopus 로고    scopus 로고
    • Analgesic tolerance to microinjection of the μ-opioid agonist DAMGO into the ventrolateral periaqueductal gray
    • DOI 10.1016/j.neuropharm.2007.03.002, PII S0028390807000603
    • P.J. Meyer, E.N. Fossum, S.L. Ingram, and M.M. Morgan Analgesic tolerance to microinjection of the micro-opioid agonist DAMGO into the ventrolateral periaqueductal gray Neuropharmacology 52 2007 1580 1585 (Pubitemid 46843132)
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1580-1585
    • Meyer, P.J.1    Fossum, E.N.2    Ingram, S.L.3    Morgan, M.M.4
  • 37
    • 0024412504 scopus 로고
    • Behavioural tolerance to morphine analgesia is supraspinally mediated: A quantitative analysis of dose-response relationships
    • DOI 10.1016/0006-8993(89)90066-8
    • R.J. Milne, G.D. Gamble, and N.H. Holford Behavioural tolerance to morphine analgesia is supraspinally mediated: A quantitative analysis of dose-response relationships Brain Res 491 1989 316 327 (Pubitemid 19163381)
    • (1989) Brain Research , vol.491 , Issue.2 , pp. 316-327
    • Milne, R.J.1    Gamble, G.D.2    Holford, N.H.G.3
  • 38
    • 70349255508 scopus 로고    scopus 로고
    • Glutamate modulation of antinociception, but not tolerance, produced by morphine microinjection into the periaqueductal gray of the rat
    • M.M. Morgan, E.N. Bobeck, and S.L. Ingram Glutamate modulation of antinociception, but not tolerance, produced by morphine microinjection into the periaqueductal gray of the rat Brain Res 1295 2009 59 66
    • (2009) Brain Res , vol.1295 , pp. 59-66
    • Morgan, M.M.1    Bobeck, E.N.2    Ingram, S.L.3
  • 39
    • 33751090449 scopus 로고    scopus 로고
    • Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat
    • DOI 10.1016/j.pbb.2006.08.003, PII S0091305706002607
    • M.M. Morgan, E.N. Fossum, C.S. Levine, and S.L. Ingram Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat Pharmacol Biochem Behav 85 2006 214 219 (Pubitemid 44772923)
    • (2006) Pharmacology Biochemistry and Behavior , vol.85 , Issue.1 , pp. 214-219
    • Morgan, M.M.1    Fossum, E.N.2    Levine, C.S.3    Ingram, S.L.4
  • 40
    • 33646035464 scopus 로고    scopus 로고
    • Morphine antinociceptive potency on chemical, mechanical, and thermal nociceptive tests in the rat
    • M.M. Morgan, E.N. Fossum, B.M. Stalding, and M.M. King Morphine antinociceptive potency on chemical, mechanical, and thermal nociceptive tests in the rat J Pain 7 2006 358 366
    • (2006) J Pain , vol.7 , pp. 358-366
    • Morgan, M.M.1    Fossum, E.N.2    Stalding, B.M.3    King, M.M.4
  • 41
    • 26844493844 scopus 로고    scopus 로고
    • Intermittent dosing prolongs tolerance to the antinociceptive effect of morphine microinjection into the periaqueductal gray
    • DOI 10.1016/j.brainres.2005.08.024, PII S0006899305012035
    • M.M. Morgan, B.W. Tierney, and S.L. Ingram Intermittent dosing prolongs tolerance to the antinociceptive effect of morphine microinjection into the periaqueductal gray Brain Res 1059 2005 173 178 (Pubitemid 41457315)
    • (2005) Brain Research , vol.1059 , Issue.2 , pp. 173-178
    • Morgan, M.M.1    Tierney, B.W.2    Ingram, S.L.3
  • 42
    • 0032584966 scopus 로고    scopus 로고
    • Immobility and flight associated with antinociception produced by activation of the ventral and lateral/dorsal regions of the rat periaqueductal gray
    • DOI 10.1016/S0006-8993(98)00669-6, PII S0006899398006696
    • M.M. Morgan, P.K. Whitney, and M.S. Gold Immobility and flight associated with antinociception produced by activation of the ventral and lateral/dorsal regions of the rat periaqueductal gray Brain Res 804 1998 159 166 (Pubitemid 28410492)
    • (1998) Brain Research , vol.804 , Issue.1 , pp. 159-166
    • Morgan, M.M.1    Whitney, P.K.2    Gold, M.S.3
  • 45
    • 0031854821 scopus 로고    scopus 로고
    • Microdialysis of excitatory amino acids in the periaqueductal gray of the rat after unilateral peripheral inflammation
    • DOI 10.1007/BF01318851
    • W.M. Renno Microdialysis of excitatory amino acids in the periaqueductal gray of the rat after unilateral peripheral inflammation Amino Acids 14 1998 319 331 (Pubitemid 28349822)
    • (1998) Amino Acids , vol.14 , Issue.4 , pp. 319-331
    • Renno, W.M.1
  • 46
    • 0031738966 scopus 로고    scopus 로고
    • Prolonged noxious stimulation increases Periaqueductal gray NMDA mRNA expression: A hybridization study using two different rat models for nociception
    • W.M. Renno Prolonged noxious stimulation increases periaqueductal gray NMDA mRNA expression: A hybridization study using two different rat models for nociception Ir J Med Sci 167 1998 181 192 (Pubitemid 28510989)
    • (1998) Irish Journal of Medical Science , vol.167 , Issue.3 , pp. 181-192
    • Renno, W.M.1
  • 47
    • 0033104091 scopus 로고    scopus 로고
    • Peripheral inflammation is associated with decreased veratridine- induced release of GABA in the rat ventrocaudal periaqueductal gray: Microdialysis study
    • DOI 10.1016/S0022-510X(98)00327-X, PII S0022510X9800327X
    • W.M. Renno, and A.J. Beitz Peripheral inflammation is associated with decreased veratridine-induced release of GABA in the rat ventrocaudal periaqueductal gray: Microdialysis study J Neurol Sci 163 1999 105 110 (Pubitemid 29234232)
    • (1999) Journal of the Neurological Sciences , vol.163 , Issue.2 , pp. 105-110
    • Renno, W.M.1    Beitz, A.J.2
  • 48
    • 84860990808 scopus 로고    scopus 로고
    • Enhancement of antinociception by co-administrations of nefopam, morphine, and nimesulide in a rat model of neuropathic pain
    • E. Saghaei, T. Moini Zanjani, M. Sabetkasaei, and K. Naseri Enhancement of antinociception by co-administrations of nefopam, morphine, and nimesulide in a rat model of neuropathic pain Korean J Pain 25 2012 7 15
    • (2012) Korean J Pain , vol.25 , pp. 7-15
    • Saghaei, E.1    Moini Zanjani, T.2    Sabetkasaei, M.3    Naseri, K.4
  • 49
    • 67649816780 scopus 로고    scopus 로고
    • Involvement of the nociceptin/orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain
    • G.M. Scoto, G. Arico, A. Iemolo, S. Ronsisvalle, and C. Parenti Involvement of the nociceptin/orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain Life Sci 85 2009 206 210
    • (2009) Life Sci , vol.85 , pp. 206-210
    • Scoto, G.M.1    Arico, G.2    Iemolo, A.3    Ronsisvalle, S.4    Parenti, C.5
  • 50
    • 0023605569 scopus 로고
    • Tolerance to morphine microinjections in the periaqueductal gray (PAG) induces tolerance to systemic, but not intrathecal morphine
    • DOI 10.1016/0006-8993(87)91476-4
    • J.A. Siuciak, and C. Advokat Tolerance to morphine microinjections in the periaqueductal gray (PAG) induces tolerance to systemic, but not intrathecal morphine Brain Res 424 1987 311 319 (Pubitemid 18047676)
    • (1987) Brain Research , vol.424 , Issue.2 , pp. 311-319
    • Siuciak, J.A.1    Advokat, C.2
  • 52
    • 0037333777 scopus 로고    scopus 로고
    • Involvement of local cholecystokinin in the tolerance induced by morphine microinjections into the periaqueductal gray of rats
    • DOI 10.1016/s0304-3959(02)00153-7
    • V. Tortorici, L. Nogueira, R. Salas, and H. Vanegas Involvement of local cholecystokinin in the tolerance induced by morphine microinjections into the periaqueductal gray of rats Pain 102 2003 9 16 (Pubitemid 36298857)
    • (2003) Pain , vol.102 , Issue.1-2 , pp. 9-16
    • Tortorici, V.1    Nogueira, L.2    Salas, R.3    Vanegas, H.4
  • 53
    • 0032887188 scopus 로고    scopus 로고
    • Tolerance to the antinociceptive effect of morphine microinjections into the ventral but not lateral-dorsal periaqueductal gray of the rat
    • DOI 10.1037/0735-7044.113.4.833
    • V. Tortorici, C.S. Robbins, and M.M. Morgan Tolerance to the antinociceptive effect of morphine microinjections into the ventral but not lateral-dorsal periaqueductal gray of the rat Behav Neurosci 113 1999 833 839 (Pubitemid 29426702)
    • (1999) Behavioral Neuroscience , vol.113 , Issue.4 , pp. 833-839
    • Tortorici, V.1    Robbins, C.S.2    Morgan, M.M.3
  • 54
    • 79951559990 scopus 로고    scopus 로고
    • Chronic inflammatory pain does not attenuate the development of tolerance to chronic morphine in adult male rats
    • M.L. Uhelski, J.A. Boyette-Davis, and P.N. Fuchs Chronic inflammatory pain does not attenuate the development of tolerance to chronic morphine in adult male rats Pharmacol Biochem Behav 98 2011 325 330
    • (2011) Pharmacol Biochem Behav , vol.98 , pp. 325-330
    • Uhelski, M.L.1    Boyette-Davis, J.A.2    Fuchs, P.N.3
  • 55
    • 0027385201 scopus 로고
    • Morphine fails to produce tolerance when administered in the presence of formalin pain in rats
    • DOI 10.1016/0006-8993(93)90332-H
    • A.L. Vaccarino, P. Marek, B. Kest, S. Ben-Eliyahu, L.C. Couret, B. Kao, and J.C. Liebeskind Morphine fails to produce tolerance when administered in the presence of formalin pain in rats Brain Res 627 1993 287 290 (Pubitemid 23313266)
    • (1993) Brain Research , vol.627 , Issue.2 , pp. 287-290
    • Vaccarino, A.L.1    Marek, P.2    Kest, B.3    Ben-Eliyahu, S.4    Couret Jr., L.C.5    Kao, B.6    Liebeskind, J.C.7
  • 56
    • 0030986006 scopus 로고    scopus 로고
    • Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats
    • DOI 10.1016/S0304-3959(97)03337-X, PII S030439599703337X
    • S. Wegert, M.H. Ossipov, M.L. Nichols, D. Bian, T.W. Vanderah, T.P. Malan, and F. Porreca Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats Pain 71 1997 57 64 (Pubitemid 27245231)
    • (1997) Pain , vol.71 , Issue.1 , pp. 57-64
    • Wegert, S.1    Ossipov, M.H.2    Nichols, M.L.3    Bian, D.4    Vanderah, T.W.5    Malan Jr., T.P.6    Porreca, F.7
  • 57
    • 0027273215 scopus 로고
    • Chronic pain increases brainstem proneurotensin/neuromedin-N mRNA expression: A hybridization-histochemical and immunohistochemical study using three different rat models for chronic nociception
    • F.G. Williams, and A.J. Beitz Chronic pain increases brainstem proneurotensin/neuromedin-N mRNA expression: A hybridization-histochemical and immunohistochemical study using three different rat models for chronic nociception Brain Res 611 1993 87 102 (Pubitemid 23153362)
    • (1993) Brain Research , vol.611 , Issue.1 , pp. 87-102
    • Williams, F.G.1    Beitz, A.J.2
  • 58
    • 0036839399 scopus 로고    scopus 로고
    • 2A receptor mRNA in some nuclei of brain stem enhanced in monoarthritic rats
    • DOI 10.1016/S0006-8993(02)03347-4, PII S0006899302033474
    • H. Xie, F. Ma, Y.Q. Zhang, X. Gao, and G.C. Wu Expression of 5-HT(2A) receptor mRNA in some nuclei of brain stem enhanced in monoarthritic rats Brain Res 954 2002 94 99 (Pubitemid 35223445)
    • (2002) Brain Research , vol.954 , Issue.1 , pp. 94-99
    • Xie, H.1    Ma, F.2    Zhang, Y.-Q.3    Gao, X.4    Wu, G.-C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.