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Volumn 27, Issue 6, 2008, Pages 1517-1524

Sexually dimorphic activation of the periaqueductal gray-rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat

Author keywords

Analgesia; Anatomy; Descending modulatory pathway; Pain

Indexed keywords

MORPHINE;

EID: 40949133434     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06100.x     Document Type: Article
Times cited : (50)

References (55)
  • 1
    • 30644458052 scopus 로고    scopus 로고
    • Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine
    • Bagley, E.E., Chieng, B.C., Christie, M.J. Connor, M. (2005) Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine. Br. J. Pharmacol., 146, 68 76.
    • (2005) Br. J. Pharmacol. , vol.146 , pp. 68-76
    • Bagley, E.E.1    Chieng, B.C.2    Christie, M.J.3    Connor, M.4
  • 2
    • 0023864182 scopus 로고
    • Integrated defence reaction elicited by excitatory amino acid microinjection in the midbrain periaqueductal grey region of the unrestrained cat
    • Bandler, R. Carrive, P. (1988) Integrated defence reaction elicited by excitatory amino acid microinjection in the midbrain periaqueductal grey region of the unrestrained cat. Brain Res., 439, 95 106.
    • (1988) Brain Res. , vol.439 , pp. 95-106
    • Bandler, R.1    Carrive, P.2
  • 3
    • 0021951462 scopus 로고
    • Identification of midbrain neurones mediating defensive behaviour in the rat by microinjections of excitatory amino acids
    • Bandler, R., Depaulis, A. Vergnes, M. (1985) Identification of midbrain neurones mediating defensive behaviour in the rat by microinjections of excitatory amino acids. Behav. Brain Res., 15, 107 119.
    • (1985) Behav. Brain Res. , vol.15 , pp. 107-119
    • Bandler, R.1    Depaulis, A.2    Vergnes, M.3
  • 4
    • 0034749640 scopus 로고    scopus 로고
    • Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids
    • Barrett, A.C., Cook, C.D., Terner, J.M., Craft, R.M. Picker, M.J. (2001) Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids. Psychopharmacology (Berl.), 158, 154 164.
    • (2001) Psychopharmacology (Berl.) , vol.158 , pp. 154-164
    • Barrett, A.C.1    Cook, C.D.2    Terner, J.M.3    Craft, R.M.4    Picker, M.J.5
  • 5
    • 0018420264 scopus 로고
    • Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia
    • Behbehani, M.M. Fields, H.L. (1979) Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia. Brain Res., 170, 85 93.
    • (1979) Brain Res. , vol.170 , pp. 85-93
    • Behbehani, M.M.1    Fields, H.L.2
  • 6
    • 0025037644 scopus 로고
    • The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat
    • Behbehani, M.M., Jiang, M.R., Chandler, S.D. Ennis, M. (1990) The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat. Pain, 40, 195 204.
    • (1990) Pain , vol.40 , pp. 195-204
    • Behbehani, M.M.1    Jiang, M.R.2    Chandler, S.D.3    Ennis, M.4
  • 7
    • 0020039181 scopus 로고
    • The organization of afferent projections to the midbrain periaqueductal gray of the rat
    • Beitz, A.J. (1982) The organization of afferent projections to the midbrain periaqueductal gray of the rat. Neuroscience, 7, 133 159.
    • (1982) Neuroscience , vol.7 , pp. 133-159
    • Beitz, A.J.1
  • 8
    • 0020679017 scopus 로고
    • The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin
    • Beitz, A.J., Shepard, R.D. Wells, W.E. (1983) The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin. Brain Res., 261, 132 137.
    • (1983) Brain Res. , vol.261 , pp. 132-137
    • Beitz, A.J.1    Shepard, R.D.2    Wells, W.E.3
  • 9
    • 33846013254 scopus 로고    scopus 로고
    • PAG mu opioid receptor activation underlies sex differences in morphine antinociception
    • Bernal, S.A., Morgan, M.M. Craft, R.M. (2007) PAG mu opioid receptor activation underlies sex differences in morphine antinociception. Behav. Brain Res., 177, 126 133.
    • (2007) Behav. Brain Res. , vol.177 , pp. 126-133
    • Bernal, S.A.1    Morgan, M.M.2    Craft, R.M.3
  • 10
    • 33751514485 scopus 로고    scopus 로고
    • Neuronal excitability in the periaqueductal grey matter during the estrous cycle in female Wistar rats
    • Brack, K.E. Lovick, T.A. (2007) Neuronal excitability in the periaqueductal grey matter during the estrous cycle in female Wistar rats. Neuroscience, 144, 325 335.
    • (2007) Neuroscience , vol.144 , pp. 325-335
    • Brack, K.E.1    Lovick, T.A.2
  • 11
    • 33645231857 scopus 로고    scopus 로고
    • Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
    • Breivik, H., Collett, B., Ventafridda, V., Cohen, R. Gallacher, D. (2006) Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur. J. Pain, 10, 287 333.
    • (2006) Eur. J. Pain , vol.10 , pp. 287-333
    • Breivik, H.1    Collett, B.2    Ventafridda, V.3    Cohen, R.4    Gallacher, D.5
  • 12
    • 0002789720 scopus 로고
    • Functional organization of PAG neurons controlling regional vascular beds
    • In. Depaulis, A. Bandler, R. (Eds), Plenum Press, New York, pp.
    • Carrive, P. (1991) Functional organization of PAG neurons controlling regional vascular beds. In Depaulis, A. Bandler, R. (Eds), The Midbrain Periaqueductal Gray Matter. Plenum Press, New York, pp. 67 100.
    • (1991) The Midbrain Periaqueductal Gray Matter. , pp. 67-100
    • Carrive, P.1
  • 13
    • 0042455233 scopus 로고    scopus 로고
    • Women experience more pain and require more morphine than men to achieve a similar degree of analgesia
    • Cepeda, M.S. Carr, D.B. (2003) Women experience more pain and require more morphine than men to achieve a similar degree of analgesia. Anesth. Analg., 97, 1464 1468.
    • (2003) Anesth. Analg. , vol.97 , pp. 1464-1468
    • Cepeda, M.S.1    Carr, D.B.2
  • 14
    • 0027930617 scopus 로고
    • Inhibition by opioids acting on mu-receptors of GABAergic and glutamatergic postsynaptic potentials in single rat periaqueductal gray neurones in vitro
    • Chieng, B. Christie, M.J. (1994) Inhibition by opioids acting on mu-receptors of GABAergic and glutamatergic postsynaptic potentials in single rat periaqueductal gray neurones in vitro. Br. J. Pharmacol., 113, 303 309.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 303-309
    • Chieng, B.1    Christie, M.J.2
  • 15
    • 0030802504 scopus 로고    scopus 로고
    • Sex-related differences in morphine's antinociceptive activity: Relationship to serum and brain morphine concentrations
    • Cicero, T.J., Nock, B. Meyer, E.R. (1997) Sex-related differences in morphine's antinociceptive activity: relationship to serum and brain morphine concentrations. J. Pharmacol. Exp. Ther., 282, 939 944.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 939-944
    • Cicero, T.J.1    Nock, B.2    Meyer, E.R.3
  • 16
    • 0034678918 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic relations of mu-opioid receptors to gamma-aminobutyric acid-immunoreactive and medullary-projecting periaqueductal gray neurons
    • Commons, K.G., Aicher, S.A., Kow, L.M. Pfaff, D.W. (2000) Presynaptic and postsynaptic relations of mu-opioid receptors to gamma-aminobutyric acid-immunoreactive and medullary-projecting periaqueductal gray neurons. J. Comp. Neurol., 419, 532 542.
    • (2000) J. Comp. Neurol. , vol.419 , pp. 532-542
    • Commons, K.G.1    Aicher, S.A.2    Kow, L.M.3    Pfaff, D.W.4
  • 17
    • 15744366900 scopus 로고    scopus 로고
    • Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats
    • Cook, C.D. Nickerson, M.D. (2005) Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats. J. Pharmacol. Exp. Ther., 313, 449 459.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 449-459
    • Cook, C.D.1    Nickerson, M.D.2
  • 18
    • 0037414402 scopus 로고    scopus 로고
    • Sex differences in drug- and non-drug-induced analgesia
    • Craft, R.M. (2003) Sex differences in drug- and non-drug-induced analgesia. Life Sci., 72, 2675 2688.
    • (2003) Life Sci. , vol.72 , pp. 2675-2688
    • Craft, R.M.1
  • 20
    • 0027510705 scopus 로고
    • Pulmonary and upper airway afferent influences on the motor pattern of vocalization evoked by excitation of the midbrain periaqueductal gray of the cat
    • Davis, P.J., Zhang, S.P. Bandler, R. (1993) Pulmonary and upper airway afferent influences on the motor pattern of vocalization evoked by excitation of the midbrain periaqueductal gray of the cat. Brain Res., 607, 61 80.
    • (1993) Brain Res. , vol.607 , pp. 61-80
    • Davis, P.J.1    Zhang, S.P.2    Bandler, R.3
  • 21
    • 0026767840 scopus 로고
    • Longitudinal neuronal organization of defensive reactions in the midbrain periaqueductal gray region of the rat
    • Depaulis, A., Keay, K.A. Bandler, R. (1992) Longitudinal neuronal organization of defensive reactions in the midbrain periaqueductal gray region of the rat. Exp. Brain Res., 90, 307 318.
    • (1992) Exp. Brain Res. , vol.90 , pp. 307-318
    • Depaulis, A.1    Keay, K.A.2    Bandler, R.3
  • 22
    • 0042572492 scopus 로고    scopus 로고
    • Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro
    • Hack, S.P., Vaughan, C.W. Christie, M.J. (2003) Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro. Neuropharmacology, 45, 575 584.
    • (2003) Neuropharmacology , vol.45 , pp. 575-584
    • Hack, S.P.1    Vaughan, C.W.2    Christie, M.J.3
  • 23
    • 0029825554 scopus 로고    scopus 로고
    • Rostral brain regions contributing to respiratory control
    • In. Holstege, G., Bandler, R. Saper, C.B. (Eds), Elsevier Science B.V., pp.
    • Harper, R.M., Rector, D., Poe, G., Frysinger, R.C., Kristensen, M. Gozal, D. (1996) Rostral brain regions contributing to respiratory control. In Holstege, G., Bandler, R. Saper, C.B. (Eds), The Emotional Motor System. Elsevier Science B.V., pp. 145 158.
    • (1996) The Emotional Motor System. , pp. 145-158
    • Harper, R.M.1    Rector, D.2    Poe, G.3    Frysinger, R.C.4    Kristensen, M.5    Gozal, D.6
  • 24
    • 0017260428 scopus 로고
    • The periaqueductal gray: Site of morphine analgesia and tolerance as shown by 2-way cross tolerance between systemic and intracerebral injections
    • Jacquet, Y.F. Lajtha, A. (1976) The periaqueductal gray: site of morphine analgesia and tolerance as shown by 2-way cross tolerance between systemic and intracerebral injections. Brain Res., 103, 501 513.
    • (1976) Brain Res. , vol.103 , pp. 501-513
    • Jacquet, Y.F.1    Lajtha, A.2
  • 25
    • 33745825500 scopus 로고    scopus 로고
    • Sex differences in morphine-induced analgesia of visceral pain are supraspinally and peripherally mediated
    • Ji, Y., Murphy, A.Z. Traub, R.J. (2006) Sex differences in morphine-induced analgesia of visceral pain are supraspinally and peripherally mediated. Am. J. Physiol. Regul. Integr. Comp. Physiol., 291, R307 R314.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.291
    • Ji, Y.1    Murphy, A.Z.2    Traub, R.J.3
  • 26
    • 0032536895 scopus 로고    scopus 로고
    • Relationship of mu- and delta-opioid receptors to GABAergic neurons in the central nervous system, including antinociceptive brainstem circuits
    • Kalyuzhny, A.E. Wessendorf, M.W. (1998) Relationship of mu- and delta-opioid receptors to GABAergic neurons in the central nervous system, including antinociceptive brainstem circuits. J. Comp. Neurol., 392, 528 547.
    • (1998) J. Comp. Neurol. , vol.392 , pp. 528-547
    • Kalyuzhny, A.E.1    Wessendorf, M.W.2
  • 27
    • 1342309260 scopus 로고    scopus 로고
    • Estrogen modulation of G-protein-coupled receptor activation of potassium channels in the central nervous system
    • Kelly, M.J., Qiu, J. Ronnekleiv, O.K. (2003) Estrogen modulation of G-protein-coupled receptor activation of potassium channels in the central nervous system. Ann. N Y Acad. Sci., 1007, 6 16.
    • (2003) Ann. N Y Acad. Sci. , vol.1007 , pp. 6-16
    • Kelly, M.J.1    Qiu, J.2    Ronnekleiv, O.K.3
  • 28
    • 0027723577 scopus 로고
    • Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear
    • Kim, J.J., Rison, R.A. Fanselow, M.S. (1993) Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear. Behav. Neurosci., 107, 1093 1098.
    • (1993) Behav. Neurosci. , vol.107 , pp. 1093-1098
    • Kim, J.J.1    Rison, R.A.2    Fanselow, M.S.3
  • 29
    • 0033528449 scopus 로고    scopus 로고
    • Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats
    • Krzanowska, E.K. Bodnar, R.J. (1999) Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats. Brain Res., 821, 224 230.
    • (1999) Brain Res. , vol.821 , pp. 224-230
    • Krzanowska, E.K.1    Bodnar, R.J.2
  • 30
    • 24044529819 scopus 로고    scopus 로고
    • Evidence for an intrinsic mechanism of antinociceptive tolerance within the ventrolateral periaqueductal gray of rats
    • Lane, D.A., Patel, P.A. Morgan, M.M. (2005) Evidence for an intrinsic mechanism of antinociceptive tolerance within the ventrolateral periaqueductal gray of rats. Neuroscience, 135, 227 234.
    • (2005) Neuroscience , vol.135 , pp. 227-234
    • Lane, D.A.1    Patel, P.A.2    Morgan, M.M.3
  • 31
    • 1642421274 scopus 로고    scopus 로고
    • Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray
    • Lane, D.A., Tortorici, V. Morgan, M.M. (2004) Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray. Neuroscience, 125, 63 69.
    • (2004) Neuroscience , vol.125 , pp. 63-69
    • Lane, D.A.1    Tortorici, V.2    Morgan, M.M.3
  • 32
    • 34250182734 scopus 로고    scopus 로고
    • Morphine preferentially activates the periaqueductal gray-rostral ventromedial medullary pathway in the male rat: A potential mechanism for sex differences in antinociception
    • Loyd, D.R., Morgan, M.M. Murphy, A.Z. (2007) Morphine preferentially activates the periaqueductal gray-rostral ventromedial medullary pathway in the male rat: a potential mechanism for sex differences in antinociception. Neuroscience, 147, 456 468.
    • (2007) Neuroscience , vol.147 , pp. 456-468
    • Loyd, D.R.1    Morgan, M.M.2    Murphy, A.Z.3
  • 33
    • 33645985808 scopus 로고    scopus 로고
    • Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: A potential circuit mediating the sexually dimorphic actions of morphine
    • Loyd, D.R. Murphy, A.Z. (2006) Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: a potential circuit mediating the sexually dimorphic actions of morphine. J. Comp. Neurol., 496, 723 738.
    • (2006) J. Comp. Neurol. , vol.496 , pp. 723-738
    • Loyd, D.R.1    Murphy, A.Z.2
  • 34
    • 33745828085 scopus 로고    scopus 로고
    • Identification of neural circuits involved in female genital responses in the rat: A dual virus and anterograde tracing study
    • Marson, L. Murphy, A.Z. (2006) Identification of neural circuits involved in female genital responses in the rat: a dual virus and anterograde tracing study. Am. J. Physiol. Regul. Integr. Comp. Physiol., 291, R419 R428.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.291
    • Marson, L.1    Murphy, A.Z.2
  • 35
    • 1642499113 scopus 로고    scopus 로고
    • Sex differences in analgesia: A randomized trial of mu versus kappa opioid agonists
    • Miller, P.L. Ernst, A.A. (2004) Sex differences in analgesia: a randomized trial of mu versus kappa opioid agonists. South Med. J., 97, 35 41.
    • (2004) South Med. J. , vol.97 , pp. 35-41
    • Miller, P.L.1    Ernst, A.A.2
  • 36
    • 11144336634 scopus 로고    scopus 로고
    • Differential susceptibility of the PAG and RVM to tolerance to the antinociceptive effect of morphine in the rat
    • Morgan, M.M., Clayton, C.C. Boyer-Quick, J.S. (2005) Differential susceptibility of the PAG and RVM to tolerance to the antinociceptive effect of morphine in the rat. Pain, 113, 91 98.
    • (2005) Pain , vol.113 , pp. 91-98
    • Morgan, M.M.1    Clayton, C.C.2    Boyer-Quick, J.S.3
  • 37
    • 33751090449 scopus 로고    scopus 로고
    • Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat
    • Morgan, M.M., Fossum, E.N., Levine, C.S. Ingram, S.L. (2006a) Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat. Pharmacol. Biochem. Behav., 85, 214 219.
    • (2006) Pharmacol. Biochem. Behav. , vol.85 , pp. 214-219
    • Morgan, M.M.1    Fossum, E.N.2    Levine, C.S.3    Ingram, S.L.4
  • 38
    • 33646035464 scopus 로고    scopus 로고
    • Morphine antinociceptive potency on chemical, mechanical, and thermal nociceptive tests in the rat
    • Morgan, M.M., Fossum, E.N., Stalding, B.M. King, M.M. (2006b) Morphine antinociceptive potency on chemical, mechanical, and thermal nociceptive tests in the rat. J. Pain, 7, 358 366.
    • (2006) J. Pain , vol.7 , pp. 358-366
    • Morgan, M.M.1    Fossum, E.N.2    Stalding, B.M.3    King, M.M.4
  • 39
    • 0029162079 scopus 로고
    • Fos expression induced by changes in arterial pressure is localized in distinct, longitudinally organized columns of neurons in the rat midbrain periaqueductal gray
    • Murphy, A.Z., Ennis, M., Rizvi, T.A., Behbehani, M.M. Shipley, M.T. (1995) Fos expression induced by changes in arterial pressure is localized in distinct, longitudinally organized columns of neurons in the rat midbrain periaqueductal gray. J. Comp. Neurol., 360, 286 300.
    • (1995) J. Comp. Neurol. , vol.360 , pp. 286-300
    • Murphy, A.Z.1    Ennis, M.2    Rizvi, T.A.3    Behbehani, M.M.4    Shipley, M.T.5
  • 40
    • 0032837239 scopus 로고    scopus 로고
    • Distribution of androgen and estrogen receptor containing neurons in the male rat periaqueductal gray
    • Murphy, A.Z. Hoffman, G.E. (1999) Distribution of androgen and estrogen receptor containing neurons in the male rat periaqueductal gray. Horm. Beh., 36, 98 108.
    • (1999) Horm. Beh. , vol.36 , pp. 98-108
    • Murphy, A.Z.1    Hoffman, G.E.2
  • 41
    • 0035903982 scopus 로고    scopus 로고
    • Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: A potential circuit for the initiation of male sexual behavior
    • Murphy, A.Z. Hoffman, G.E. (2001) Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: a potential circuit for the initiation of male sexual behavior. J. Comp. Neurol., 438, 191 212.
    • (2001) J. Comp. Neurol. , vol.438 , pp. 191-212
    • Murphy, A.Z.1    Hoffman, G.E.2
  • 42
    • 0030054174 scopus 로고    scopus 로고
    • Opioid inhibition of rat periaqueductal grey neurones with identified projections to the rostral ventromedial medulla in vitro
    • Osborne, P.B., Vaughan, C.W., Wilson, H.I. Christie, M.J. (1996) Opioid inhibition of rat periaqueductal grey neurones with identified projections to the rostral ventromedial medulla in vitro. J. Physiol. (Lond.), 490, 383 389.
    • (1996) J. Physiol. (Lond.) , vol.490 , pp. 383-389
    • Osborne, P.B.1    Vaughan, C.W.2    Wilson, H.I.3    Christie, M.J.4
  • 43
    • 0030058822 scopus 로고    scopus 로고
    • Medial preoptic area afferents to periaqueductal gray medullo-output neurons: A combined Fos and tract tracing study
    • Rizvi, T.A., Murphy, A.Z., Ennis, M., Behbehani, M.M. Shipley, M.T. (1996) Medial preoptic area afferents to periaqueductal gray medullo-output neurons: a combined Fos and tract tracing study. J. Neurosci., 16, 333 344.
    • (1996) J. Neurosci. , vol.16 , pp. 333-344
    • Rizvi, T.A.1    Murphy, A.Z.2    Ennis, M.3    Behbehani, M.M.4    Shipley, M.T.5
  • 44
    • 0026006171 scopus 로고
    • C-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress
    • Sharp, F.R., Sagar, S.M., Hicks, K., Lowenstein, D. Hisanaga, K. (1991) c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress. J. Neurosci., 11, 2321 2331.
    • (1991) J. Neurosci. , vol.11 , pp. 2321-2331
    • Sharp, F.R.1    Sagar, S.M.2    Hicks, K.3    Lowenstein, D.4    Hisanaga, K.5
  • 45
    • 0023605569 scopus 로고
    • Tolerance to morphine microinjections in the periaqueductal gray (PAG) induces tolerance to systemic, but not intrathecal morphine
    • Siuciak, J.A. Advokat, C. (1987) Tolerance to morphine microinjections in the periaqueductal gray (PAG) induces tolerance to systemic, but not intrathecal morphine. Brain Res., 424, 311 319.
    • (1987) Brain Res. , vol.424 , pp. 311-319
    • Siuciak, J.A.1    Advokat, C.2
  • 47
    • 0036796886 scopus 로고    scopus 로고
    • Comparison of morphine and kainic acid microinjections into identical PAG sites on the activity of RVM neurons
    • Tortorici, V. Morgan, M.M. (2002) Comparison of morphine and kainic acid microinjections into identical PAG sites on the activity of RVM neurons. J. Neurophysiol., 88, 1707 1715.
    • (2002) J. Neurophysiol. , vol.88 , pp. 1707-1715
    • Tortorici, V.1    Morgan, M.M.2
  • 48
    • 0032887188 scopus 로고    scopus 로고
    • Tolerance to the antinociceptive effect of morphine microinjections into the ventral but not lateral-dorsal periaqueductal gray of the rat
    • Tortorici, V., Robbins, C.S. Morgan, M.M. (1999) Tolerance to the antinociceptive effect of morphine microinjections into the ventral but not lateral-dorsal periaqueductal gray of the rat. Behav. Neurosci., 113, 833 839.
    • (1999) Behav. Neurosci. , vol.113 , pp. 833-839
    • Tortorici, V.1    Robbins, C.S.2    Morgan, M.M.3
  • 49
    • 0031033471 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro
    • Vaughan, C.W. Christie, M.J. (1997) Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. J. Physiol., 498, 463 472.
    • (1997) J. Physiol. , vol.498 , pp. 463-472
    • Vaughan, C.W.1    Christie, M.J.2
  • 51
    • 0022458884 scopus 로고
    • Use of cryoprotectant to maintain longterm peptide immunoreactivity and tissue morphology
    • Watson, R.E., Wiegand, S.J., Clough, R.W. Hoffman, G.E. (1986) Use of cryoprotectant to maintain longterm peptide immunoreactivity and tissue morphology. Peptides, 7, 155 159.
    • (1986) Peptides , vol.7 , pp. 155-159
    • Watson, R.E.1    Wiegand, S.J.2    Clough, R.W.3    Hoffman, G.E.4
  • 52
    • 0025049807 scopus 로고
    • Ultrastructural morphometric analysis of GABA-immunoreactive terminals in the ventrocaudal periaqueductal grey: Analysis of the relationship of GABA terminals and the GABAA receptor to periaqueductal grey-raphe magnus projection neurons
    • Williams, F.G. Beitz, A.J. (1990) Ultrastructural morphometric analysis of GABA-immunoreactive terminals in the ventrocaudal periaqueductal grey: analysis of the relationship of GABA terminals and the GABAA receptor to periaqueductal grey-raphe magnus projection neurons. J. Neurocytol., 19, 686 696.
    • (1990) J. Neurocytol. , vol.19 , pp. 686-696
    • Williams, F.G.1    Beitz, A.J.2
  • 53
    • 0025340052 scopus 로고
    • Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal gray of the cat
    • Zhang, S.P., Bandler, R. Carrive, P. (1990) Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal gray of the cat. Brain Res., 520, 73 82.
    • (1990) Brain Res. , vol.520 , pp. 73-82
    • Zhang, S.P.1    Bandler, R.2    Carrive, P.3
  • 54
    • 0028108575 scopus 로고
    • Brain stem integration of vocalization: Role of the midbrain periaqueductal gray
    • Zhang, S.P., Davis, P.J., Bandler, R. Carrive, P. (1994) Brain stem integration of vocalization: role of the midbrain periaqueductal gray. J. Neurophysiol., 72, 1337 1356.
    • (1994) J. Neurophysiol. , vol.72 , pp. 1337-1356
    • Zhang, S.P.1    Davis, P.J.2    Bandler, R.3    Carrive, P.4
  • 55
    • 0031057267 scopus 로고    scopus 로고
    • Anatomical localization and time course of Fos expression following soman-induced seizures
    • Zimmer, L.A., Ennis, M., el-Etri, M. Shipley, M.T. (1997) Anatomical localization and time course of Fos expression following soman-induced seizures. J. Comp. Neurol., 278, 468 481.
    • (1997) J. Comp. Neurol. , vol.278 , pp. 468-481
    • Zimmer, L.A.1    Ennis, M.2    El-Etri, M.3    Shipley, M.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.