PH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy

Acta Biomaterialia

Volumn 10, Issue 1, 2014, Pages 300-307

  Gonçalves, Mara ^a   Figueira, Priscilla ^a   Maciel, Dina ^a   Rodrigues, João ^a   Qu, Xue ^b   Liu, Changsheng ^b   Tomás, Helena ^a   Li, Yulin ^a  

^a UNIVERSITY OF MADEIRA   (Portugal)

^b East China University of Science and Technology   (China)

Author keywords

Alginate; Doxorubicin; Drug delivery; Laponite ; pH sensitive nanohybrids

Indexed keywords

ASPECT RATIO; BIOCOMPATIBILITY; CELL CULTURE; CELLS; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; ENCAPSULATION; PH SENSORS; TARGETED DRUG DELIVERY;

ACIDIC ENVIRONMENT; ANTICANCER DRUG; CATIONICS; CELLULAR UPTAKE; DOXORUBICIN; LAPONITES; LAPONITE®; NANOHYBRIDS; PH SENSITIVE; PH-SENSITIVE NANOHYBRID;

NANOSTRUCTURED MATERIALS;

ALGINIC ACID; DOXORUBICIN; NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CELL CULTURE; CELL MEMBRANE; CELL ORGANELLE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ENDOLYSOSOME; INTERNALIZATION; NANOENCAPSULATION; OSTEOSARCOMA CELL; PH; PRIORITY JOURNAL;

ALGINATE; DOXORUBICIN; DRUG DELIVERY; LAPONITE®; PH-SENSITIVE NANOHYBRIDS;

ALGINATES; ANTINEOPLASTIC AGENTS; BUFFERS; CELL DEATH; CELL LINE, TUMOR; CELL SHAPE; DOXORUBICIN; ENDOCYTOSIS; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDRODYNAMICS; HYDROGEN-ION CONCENTRATION; NANOPARTICLES; SILICATES; TITRIMETRY;

EID: 84888645933     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.09.013     Document Type: Article

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