A community-based cross-sectional and longitudinal study uncovered asymptomatic proteinuria in Japanese adults with low body weight

Kidney International

Volumn 84, Issue 6, 2013, Pages 1254-1261

  Muneyuki, Toshitaka ^a,b   Sugawara, Hitoshi ^b   Suwa, Kaname ^c   Oshida, Haruki ^a   Saito, Masafumi ^a   Hori, Yumiko ^a   Seta, Setsuko ^d   Ishida, Takeshi ^e   Kakei, Masafumi ^b   Momomura, Shin Ichi ^b   Nakajima, Kei ^a  

^a JOSAI UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c Saitama Health Promotion Corporation   (Japan)

^d SAITAMA PREFECTURAL UNIVERSITY   (Japan)

^e Saitama Citizen Medical Center   (Japan)

Author keywords

body mass index; cardiometabolic risk factors; dipstick urinalysis; low body weight; obesity; proteinuria

Indexed keywords

ADULT; AGED; ARTICLE; ASYMPTOMATIC DISEASE; BODY MASS; CARDIOMETABOLIC RISK; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; JAPANESE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; PROTEINURIA; RECURRENT DISEASE; RISK ASSESSMENT;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; ASYMPTOMATIC DISEASES; BODY WEIGHT; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INCIDENCE; JAPAN; LINEAR MODELS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PREVALENCE; PROTEINURIA; RECURRENCE; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84888641976     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.222     Document Type: Article

References (52)

1. Grimm Jr RH, Svendsen KH, Kasiske B et al. Proteinuria is a risk factor for mortality over 10 years of follow-up, MRFIT Research Group. Multiple Risk Factor Intervention Trial. Kidney Int 1997; 52(Suppl 63): 10-14.
2. Keane WF. Proteinuria: Its clinical importance and role in progressive renal disease. Am J Kidney Dis 2000; 35(4 Suppl 1): S97-105.
3. Iseki K, Ikemiya Y, Iseki C et al. Proteinuria and the risk of developing endstage renal disease. Kidney Int 2003; 63: 1468-1474.
4. Levey AS, Coresh J, Balk E et al. National Kidney Foundation practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Ann Intern Med 2003; 139: 137-147.
5. Sarnak MJ, Astor BC. Implications of proteinuria: CKD progression and cardiovascular outcomes. Adv Chronic Kidney Dis 2011; 18: 258-266.
6. Kambham N, Markowitz GS, Valeri AM et al. Obesity-related glomerulopathy: An emerging epidemic. Kidney Int 2001; 59: 1498-1509.
7. Tozawa M, Iseki K, Iseki C et al. Influence of smoking and obesity on the development of proteinuria. Kidney Int 2002; 62: 956-962.
8. Ramirez SP, McClellan W, Port FK et al. Risk factors for proteinuria in a large, multiracial, southeast Asian population. J Am Soc Nephrol 2002; 13: 1907-1917.
9. Shen WW, Chen HM, Chen H et al. Obesity-related glomerulopathy: Body mass index and proteinuria. Clin J Am Soc Nephrol 2010; 5: 1401-1409.
10. Grundy SM, Cleeman JI, Daniels SR et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-2752.
11. Dulloo AG, Jacquet J, Solinas G et al. Body composition phenotypes in pathways to obesity and the metabolic syndrome. Int J Obes (Lond) 2010; 34(Suppl 2): S4-S17.
12. Maric C, Hall JE. Obesity, metabolic syndrome and diabetic nephropathy. Contrib Nephrol 2011; 170: 28-35.
13. Tanner RM, Brown TM, Muntner P. Epidemiology of obesity, the metabolic syndrome, and chronic kidney disease. Curr Hypertens Rep 2012; 14: 152-159.
14. Praga M, Morales E. Obesity, proteinuria and progression of renal failure. Curr Opin Nephrol Hypertens 2006; 15: 481-486.
15. Bosma RJ, Krikken JA, Homan van der Heide JJ et al. Obesity and renal hemodynamics. Contrib Nephrol 2006; 151: 184-202.
16. Eknoyan G. Obesity and chronic kidney disease. Nefrologia 2011; 31: 397-403.
17. WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004; 363: 157-163.
18. Balarajan Y, Villamor E. Nationally representative surveys show recent increases in the prevalence of overweight and obesity among women of reproductive age in Bangladesh, Nepal, and India. J Nutr 2009; 139: 2139-2144.
19. Tsugane S. Alcohol, smoking, and obesity epidemiology in Japan. J Gastroenterol Hepatol 2012; 27(Suppl 2): 121-126.
20. Ramirez SP, Hsu SI, McClellan W. Low body weight is a risk factor for proteinuria in multiracial Southeast Asian pediatric population. Am J Kidney Dis 2001; 38: 1045-1054.
21. Jee SH, Sull JW, Park J et al. Body-mass index and mortality in Korean men and women. N Engl J Med 2006; 355: 779-787.
22. Berrington de Gonzalez A, Hartge P, Cerhan JR et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 2010; 363: 2211-2219.
23. Zheng W, McLerran DF, Rolland B et al. Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med 2011; 364: 719-729.
24. Fleet M, Osman F, Komaragiri R et al. Protein catabolism in advanced renal disease: Role of cytokines. Clin Nephrol 2008; 70: 91-100.
25. Ikizler TA. Nutrition, inflammation and chronic kidney disease. Curr Opin Nephrol Hypertens 2008; 17: 162-167.
26. Bonanni A, Mannucci I, Verzola D et al. Protein-energy wasting and mortality in chronic kidney disease. Int J Environ Res Public Health 2011; 8: 1631-1654.
27. Lopez-Jimenez F. Speakable and unspeakable facts about BMI and mortality. Lancet 2009; 373: 1055-1056.
28. Heifets M, Davis TA, Tegtmeyer E et al. Exercise training ameliorates progressive renal disease in rats with subtotal nephrectomy. Kidney Int 1987; 32: 815-820.
29. Pechter U, Maaroos J, Mesikepp S et al. Regular low-intensity aquatic exercise improves cardio-respiratory functional capacity and reduces proteinuria in chronic renal failure patients. Nephrol Dial Transplant 2003; 18: 624-625.
30. Slentz CA, Houmard JA, Kraus WE. Exercise, abdominal obesity, skeletal muscle, and metabolic risk: Evidence for a dose response. Obesity (Silver Spring) 2009; 17(Suppl 3): S27-S33.
31. Thyfault JP, Booth FW. Lack of regular physical exercise or too much inactivity. Curr Opin Clin Nutr Metab Care 2011; 14: 374-378.
32. Heymsfield SB, Scherzer R, Pietrobelli A et al. Body mass index as a phenotypic expression of adiposity: Quantitative contribution of muscularity in a population-based sample. Int J Obes (Lond) 2009; 33: 1363-1373.
33. Esteghamati A, Ashraf H, Nakhjavani M et al. Insulin resistance is an independent correlate of increased urine albumin excretion: A crosssectional study in Iranian type 2 diabetic patients. Diabet Med 2009; 26: 177-181.
34. Hsu CC, Chang HY, Huang MC et al. Association between insulin resistance and development of microalbuminuria in type 2 diabetes: A prospective cohort study. Diabetes Care 2011; 34: 982-987.
35. Fornoni A. Proteinuria, the podocyte, and insulin resistance. N Engl J Med 2010; 363: 2068-2069.
36. Coward RJ, Saleem MA. Podocytes as a target of insulin. Curr Diabetes Rev 2011; 7: 22-27.
37. Simerville JA, Maxted WC, Pahira JJ. Urinalysis: A comprehensive review. Am Fam Physician 2005; 71: 1153-1162.
38. Wingo CS, Clapp WL. Proteinuria: Potential causes and approach to evaluation. Am J Med Sci 2000; 320: 188-194.
39. Naderi AS, Reilly RF. Primary care approach to proteinuria. J Am Board Fam Med 2008; 21: 569-574.
40. Hoy WE, Rees M, Kile E et al. A new dimension to the Barker hypothesis: Low birth weight and susceptibility to renal disease. Kidney Int 1999; 56: 1072-1077.
41. Wani M, Kalra V, Agarwal SK. Low birth weight and its implication in renal disease. J Assoc Physicians India 2004; 52: 649-652.
42. Luyckx VA, Brenner BM. Low birth weight, nephron number, and kidney disease. Kidney Int Suppl 2005; 97: S68-S77.
43. Salmi IA, Chadban SJ, Huxley RR. Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies. Am J Kidney Dis 2009; 54: 248-261.
44. Bello AK, Peters J, Rigby J et al. Socioeconomic status and chronic kidney disease at presentation to a renal service in the United Kingdom. Clin J Am Soc Nephrol 2008; 3: 1316-1323.
45. Patzer RE, McClellan WM. Influence of race, ethnicity and socioeconomic status on kidney disease. Nat Rev Nephrol 2012; 8: 533-541.
46. Lindsey JC, Ryan LM. Tutorial in biostatistics methods for intervalcensored data. Stat Med 1998; 17: 219-238.
47. Alexander N. Precision of rate estimation under uniform interval censoring. Stat Med 2008; 27: 3442-3445.
48. Saitama Prefecture at a Glance, Saitama Prefecture. http://www.pref. saitama.lg.jp/site/english-top/english-saitama-prefecture-At-Aglance. html.
49. Saitama Health Promotion Corporation. http://www.saitamakenkou. or.jp/in Japanese.
50. Kashiwagi A, Kasuga M, Araki E et al. International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values. Diabetol Int 2012; 3: 8-10.
51. Matsuo S, Imai E, Horio M et al. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 2009; 53: 982-992.
52. Zocchetti C, Consonni D, Bertazzi PA. Relationship between prevalence rate ratios and odds ratios in cross-sectional studies. Int J Epidemiol 1997; 26: 220-223.