-
1
-
-
34447106751
-
PP2A: Unveiling a reluctant tumor suppressor
-
M. Mumby PP2A: unveiling a reluctant tumor suppressor Cell 130 2007 21 24
-
(2007)
Cell
, vol.130
, pp. 21-24
-
-
Mumby, M.1
-
2
-
-
84876990097
-
Protein phosphatase 2A: A target for anticancer therapy
-
D. Perrotti, and P. Neviani Protein phosphatase 2A: a target for anticancer therapy Lancet Oncol. 14 2013 e229 e238
-
(2013)
Lancet Oncol.
, vol.14
-
-
Perrotti, D.1
Neviani, P.2
-
3
-
-
0041925130
-
Ras signaling: PP2A puts Ksr and Raf in the right place
-
T. Raabe, and U.R. Rapp Ras signaling: PP2A puts Ksr and Raf in the right place Curr. Biol. 13 2003 R635 R637
-
(2003)
Curr. Biol.
, vol.13
-
-
Raabe, T.1
Rapp, U.R.2
-
4
-
-
0035811597
-
Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions
-
M. Jaumot, and J.F. Hancock Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions Oncogene 20 2001 3949 3958
-
(2001)
Oncogene
, vol.20
, pp. 3949-3958
-
-
Jaumot, M.1
Hancock, J.F.2
-
5
-
-
67349119515
-
Raf-independent, PP2A-dependent MEK activation in response to ERK silencing
-
D. Bae, and S. Ceryak Raf-independent, PP2A-dependent MEK activation in response to ERK silencing Biochem. Biophys. Res. Commun. 385 2009 523 527
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.385
, pp. 523-527
-
-
Bae, D.1
Ceryak, S.2
-
6
-
-
37649024728
-
Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
-
S. Andrabi, O.V. Gjoerup, J.A. Kean, T.M. Roberts, and B. Schaffhausen Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner Proc. Natl. Acad. Sci. USA 104 2007 19011 19016
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19011-19016
-
-
Andrabi, S.1
Gjoerup, O.V.2
Kean, J.A.3
Roberts, T.M.4
Schaffhausen, B.5
-
7
-
-
84874599503
-
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression
-
R. Patel, M. Gao, I. Ahmad, J. Fleming, L.B. Singh, T.S. Rai, A.B. McKie, M. Seywright, R.J. Barnetson, J. Edwards, O.J. Sansom, and H.Y. Leung Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression J. Clin. Invest. 123 2013 1157 1175
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1157-1175
-
-
Patel, R.1
Gao, M.2
Ahmad, I.3
Fleming, J.4
Singh, L.B.5
Rai, T.S.6
McKie, A.B.7
Seywright, M.8
Barnetson, R.J.9
Edwards, J.10
Sansom, O.J.11
Leung, H.Y.12
-
8
-
-
84876543948
-
Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy
-
I. Arrouss, F. Nemati, F. Roncal, M. Wislez, K. Dorgham, D. Vallerand, N. Rabbe, N. Karboul, F. Carlotti, J. Bravo, D. Mazier, D. Decaudin, and A. Rebollo Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy PLoS ONE 8 2013 e60816
-
(2013)
PLoS ONE
, vol.8
, pp. 60816
-
-
Arrouss, I.1
Nemati, F.2
Roncal, F.3
Wislez, M.4
Dorgham, K.5
Vallerand, D.6
Rabbe, N.7
Karboul, N.8
Carlotti, F.9
Bravo, J.10
Mazier, D.11
Decaudin, D.12
Rebollo, A.13
-
9
-
-
24944485819
-
Cancer-associated PP2A alpha subunits induce functional haploinsufficiency and tumorigenicity
-
W. Chen, J.D. Arroyo, J.C. Timmons, R. Possemato, and W.C. Hahn Cancer-associated PP2A alpha subunits induce functional haploinsufficiency and tumorigenicity Cancer Res. 65 2005 8183 8192
-
(2005)
Cancer Res.
, vol.65
, pp. 8183-8192
-
-
Chen, W.1
Arroyo, J.D.2
Timmons, J.C.3
Possemato, R.4
Hahn, W.C.5
-
10
-
-
34447283580
-
CIP2A inhibits PP2A in human malignancies
-
M.R. Junttila, P. Puustinen, M. Niemelä, R. Ahola, H. Arnold, T. Böttzauw, R. Ala-aho, C. Nielsen, J. Ivaska, Y. Taya, S.L. Lu, S. Lin, E.K. Chan, X.J. Wang, R. Grènman, J. Kast, T. Kallunki, R. Sears, V.M. Kähäri, and J. Westermarck CIP2A inhibits PP2A in human malignancies Cell 130 2007 51 62
-
(2007)
Cell
, vol.130
, pp. 51-62
-
-
Junttila, M.R.1
Puustinen, P.2
Niemelä, M.3
Ahola, R.4
Arnold, H.5
Böttzauw, T.6
Ala-Aho, R.7
Nielsen, C.8
Ivaska, J.9
Taya, Y.10
Lu, S.L.11
Lin, S.12
Chan, E.K.13
Wang, X.J.14
Grènman, R.15
Kast, J.16
Kallunki, T.17
Sears, R.18
Kähäri, V.M.19
Westermarck, J.20
more..
-
11
-
-
84878431342
-
Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
-
P. Seshacharyulu, P. Pandey, K. Datta, and S.K. Batra Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer Cancer Lett. 335 2013 9 18
-
(2013)
Cancer Lett.
, vol.335
, pp. 9-18
-
-
Seshacharyulu, P.1
Pandey, P.2
Datta, K.3
Batra, S.K.4
-
12
-
-
33750006297
-
Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
-
Y. Xing, Y. Xu, Y. Chen, P.D. Jeffrey, Y. Chao, Z. Lin, Z. Li, S. Strack, J.B. Stock, and Y. Shi Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins Cell 127 2006 341 353
-
(2006)
Cell
, vol.127
, pp. 341-353
-
-
Xing, Y.1
Xu, Y.2
Chen, Y.3
Jeffrey, P.D.4
Chao, Y.5
Lin, Z.6
Li, Z.7
Strack, S.8
Stock, J.B.9
Shi, Y.10
-
13
-
-
77956913965
-
PPP2R2C, a gene disrupted in autosomal dominant intellectual disability
-
L. Backx, J. Vermeesch, E. Pijkels, T. de Ravel, E. Seuntjens, and H. Van Esch PPP2R2C, a gene disrupted in autosomal dominant intellectual disability Eur. J. Med. Genet. 53 2010 239 243
-
(2010)
Eur. J. Med. Genet.
, vol.53
, pp. 239-243
-
-
Backx, L.1
Vermeesch, J.2
Pijkels, E.3
De Ravel, T.4
Seuntjens, E.5
Van Esch, H.6
-
14
-
-
37749015044
-
A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC
-
P.J. Eichhorn, M.P. Creyghton, K. Wilhelmsen, H. van Dam, and R. Bernards A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC PLoS Genet. 3 2007 e218
-
(2007)
PLoS Genet.
, vol.3
, pp. 218
-
-
Eichhorn, P.J.1
Creyghton, M.P.2
Wilhelmsen, K.3
Van Dam, H.4
Bernards, R.5
-
15
-
-
84879316438
-
PPP2R2C loss promotes castration-resistant prostate cancer growth and is associated with increased prostate cancer-specific mortality
-
[Epub ahead of print]
-
E.G. Bluemn, E.S. Spencer, B. Mecham, R.R. Gordon, I. Coleman, D. Lewinshtein, E. Mostaghel, X. Zhang, J. Annis, C. Grandori, C. Porter, and P.S. Nelson PPP2R2C loss promotes castration-resistant prostate cancer growth and is associated with increased prostate cancer-specific mortality Mol. Cancer Res. 2013 14 [Epub ahead of print]
-
(2013)
Mol. Cancer Res.
, pp. 14
-
-
Bluemn, E.G.1
Spencer, E.S.2
Mecham, B.3
Gordon, R.R.4
Coleman, I.5
Lewinshtein, D.6
Mostaghel, E.7
Zhang, X.8
Annis, J.9
Grandori, C.10
Porter, C.11
Nelson, P.S.12
-
16
-
-
34347220473
-
Defining the role of mTOR in cancer
-
D.A. Guertin, and D.M. Sabatini Defining the role of mTOR in cancer Cancer Cell 12 2007 9 22
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
17
-
-
77953844482
-
MTOR signaling in cancer cell motility and tumor metastasis
-
H. Zhou, and S. Huang MTOR signaling in cancer cell motility and tumor metastasis Crit. Rev. Eukaryot. Gene Expr. 20 2010 1 16
-
(2010)
Crit. Rev. Eukaryot. Gene Expr.
, vol.20
, pp. 1-16
-
-
Zhou, H.1
Huang, S.2
-
18
-
-
33748040410
-
Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells
-
D.J. Messner, C. Romeo, A. Boynton, and S. Rossie Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells J. Cell. Biochem. 99 2006 241 255
-
(2006)
J. Cell. Biochem.
, vol.99
, pp. 241-255
-
-
Messner, D.J.1
Romeo, C.2
Boynton, A.3
Rossie, S.4
-
19
-
-
43049099609
-
SV40 small T antigen and PP2A phosphatase in cell transformation
-
A.A. Sablina, and W.C. Hahn SV40 small T antigen and PP2A phosphatase in cell transformation Cancer Metastasis Rev. 27 2008 137 146
-
(2008)
Cancer Metastasis Rev.
, vol.27
, pp. 137-146
-
-
Sablina, A.A.1
Hahn, W.C.2
-
20
-
-
37749015044
-
A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC
-
P.J. Eichhorn, M.P. Creyghton, K. Wilhelmsen, H. van Dam, and R. Bernards A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC PLoS Genet. 3 2007 e218
-
(2007)
PLoS Genet.
, vol.3
, pp. 218
-
-
Eichhorn, P.J.1
Creyghton, M.P.2
Wilhelmsen, K.3
Van Dam, H.4
Bernards, R.5
-
21
-
-
0037085451
-
ATM-dependent dissociation of B55 regulatory subunit from nuclear PP2A in response to ionizing radiation
-
C.Y. Guo, D.L. Brautigan, and J.M. Larner ATM-dependent dissociation of B55 regulatory subunit from nuclear PP2A in response to ionizing radiation J. Biol. Chem. 277 2002 4839 4844
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4839-4844
-
-
Guo, C.Y.1
Brautigan, D.L.2
Larner, J.M.3
-
22
-
-
70350142284
-
Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development
-
R.F. O'Shaughnessy, J.C. Welti, K. Sully, and C. Byrne Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development Development 136 2009 3423 3431
-
(2009)
Development
, vol.136
, pp. 3423-3431
-
-
O'Shaughnessy, R.F.1
Welti, J.C.2
Sully, K.3
Byrne, C.4
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