The differential impact of unique behavioral and psychological symptoms for the dementia caregiver: How and why do patients' individual symptom clusters impact caregiver depressive symptoms?

American Journal of Geriatric Psychiatry

Volumn 21, Issue 12, 2013, Pages 1277-1286

  Ornstein, Katherine ^a   Gaugler, Joseph E ^d   Devanand, D P ^b,c   Scarmeas, Nikos ^c   Zhu, Carolyn ^a   Stern, Yaakov ^c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Alzheimer dementia; BPSD; Caregiver depression

Indexed keywords

AGED; AGGRESSION; ALZHEIMER DISEASE; ARTICLE; BEHAVIOR DISORDER; BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH DEMENTIA; CAREGIVER BURDEN; DEMENTIA; DEPRESSION; EMPATHY; FEMALE; HUMAN; LEWY BODY; MAJOR CLINICAL STUDY; MALE; PARANOIA; PSYCHOSIS; SYMPTOMATOLOGY;

ALZHEIMER DEMENTIA; BPSD; CAREGIVER DEPRESSION;

AGED; AGED, 80 AND OVER; AGGRESSION; ALZHEIMER DISEASE; CAREGIVERS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DELUSIONS; DEPRESSION; FEMALE; HUMANS; LEWY BODY DISEASE; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PROSPECTIVE STUDIES; QUALITY OF LIFE;

EID: 84888639310     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1016/j.jagp.2013.01.062     Document Type: Article

References (43)

1. Pinquart M, Sorensen S: Associations of stressors and uplifts of caregiving with caregiver burden and depressive mood: a metaanalysis. J Gerontol B Psychol Sci Soc Sci 2003;58(2):112-128
2. Ballard C, Lowery K, Powell I, et al: Impact of behavioral and psychological symptoms of dementia on caregivers. Int Psychogeriatr 2000;12(suppl 1):93-105
3. Schulz R, O'Brien AT, Bookwala J, et al: Psychiatric and physical morbidity effects of dementia caregiving: prevalence, correlates, and causes. Gerontologist 1995;35(6):771-791
4. Schulz R, Williamson GM: A 2-year longitudinal study of depression among Alzheimer's caregivers. Psychol Aging 1991;6(4):569-578
5. Aneshensel CS, Pearlin LI, Mullan JT, et al: Profiles in Caregiving: The Unexpected Career. San Diego, Academic Press, 1995
6. Rocca P, Leotta D, Liffredo C, et al: Neuropsychiatric symptoms underlying caregiver stress and insight in Alzheimer's disease. Dement Geriatr Cogn Disord 2010;30(1):57-63
7. Mohamed S, Rosenheck R, Lyketsos CG, et al: Caregiver burden in Alzheimer disease: cross-sectional and longitudinal patient correlates. Am J Geriatr Psychiatry 2010;18(10):917-927
8. Ballard CG, Saad K, Coope B, et al: The aetiology of depression in the carers of dementia sufferers. J Affect Disord 1995;35(1/2):59-63
9. Neundorfer MM, McClendon MJ, Smyth KA, et al: A longitudinal study of the relationship between levels of depression among persons with Alzheimer's disease and levels of depression among their family caregivers. J Gerontol B Psychol Sci Soc Sci 2001;56(5):301-313
10. Gonzalez-Salvador MT, Arango C, Lyketsos CG, et al: The stress and psychological morbidity of the Alzheimer patient caregiver. Int J Geriatr Psychiatry 1999;14(9):701-710
11. Lim YM, Son GR, Song JA, et al: Factors affecting burden of family caregivers of community-dwelling ambulatory elders with dementia in Korea. Arch Psychiatr Nurs 2008;22(4):226-234
12. Donaldson C, Tarrier N, Burns A: Determinants of carer stress in Alzheimer's disease. Int J Geriatr Psychiatry 1998;13(4):248-256
13. Harwood DG, Barker WW, Cantillon M, et al: Depressive symptomatology in first-degree family caregivers of Alzheimer disease patients: a cross-ethnic comparison. Alzheimer Dis Assoc Disord 1998;12(4):340-346
14. Pearlin LI, Mullan JT, Semple SJ, et al: Caregiving and the stress process: an overview of concepts and their measures. Gerontologist 1990;30(5):583-594
15. Hooker K, Bowman SR, Coehlo DP, et al: Behavioral change in persons with dementia: relationships with mental and physical health of caregivers. J Gerontol B Psychol Sci Soc Sci 2002;57(5):453-460
16. Son J, Erno A, Shea DG, et al: The caregiver stress process and health outcomes. J Aging Health 2007;19(6):871-887
17. Goode KT, Haley WE, Roth DL, et al: Predicting longitudinal changes in caregiver physical and mental health: a stress process model. Health Psychol 1998;17(2):190-198
18. Schulz R, Hebert RS, Dew MA, et al: Patient suffering and caregiver compassion: new opportunities for research, practice, and policy. Gerontologist 2007;47(1):4-13
19. Stern Y, Folstein M, Albert M, et al: Multicenter study of predictors of disease course in Alzheimer disease (the "Predictors Study"), part I: study design, cohort description, and intersite comparisons. Alzheimer Dis Assoc Disord 1993;7(1):3-21
20. McKhann G, Drachman D, Folstein M, et al: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34(7):939-944
21. Stern Y, Sano M, Paulson J, et al: Modified Mini-Mental State Examination: validity and reliability. Neurology 1987;37(2, suppl 1):179
22. Folstein MF, Folstein SE, McHugh PR: Mini Mental State: a practical state for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198
23. McKeith IG, Galasko D, Kosaka K, et al: Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. Neurology 1996;47(5):1113-1124
24. Derogatis L: The Brief Symptom Inventory (BSI): Administration, Scoring and Procedures Manual. Minneapolis, MN, NCS Pearson, 1993
25. Nunnally J, Bernstein I: Psychometric Theory. New York, NY, McGraw Hill, 1994
26. Devanand DP, Miller L, Richards M, et al: The Columbia University Scale for Psychopathology in Alzheimer's Disease. Arch Neurol 1992;49(4):371-376
27. Blessed G, Tomlinson BE, Roth M: The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968;114(512):797-811
28. Charlson ME, Pompei P, Ales KL, et al: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40(5):373-383
29. Marcus R, Marder K, Bell K, et al: Interrater reliability of extrapyramidal signs in a group assessed for dementia. Arch Neurol 1991;48(11):1147-1149
30. Higginson IJ, Gao W, Jackson D, et al: Short-form Zarit Caregiver Burden Interviews were valid in advanced conditions. J Clin Epidemiol 2010;63(5):535-542
31. Baron RM, Kenny DA: The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986;51(6):1173-1182
32. Rindskopf D: Linear equality restrictions in regression and loglinear models. Psychol Bull 1984;96(3):597-603
33. Lyketsos CG, Steele C, Baker L, et al: Major and minor depression in Alzheimer's disease: prevalence and impact. J Neuropsychiatry Clin Neurosci 1997;9(4):556-561
34. Lyketsos CG, Steinberg M, Tschanz JT, et al: Mental and behavioral disturbances in dementia: findings fromthe Cache County Study on Memory in Aging. Am J Psychiatry 2000;157(5):708-714
35. Nelson JC, Devanand DP: A systematic review and meta-analysis of placebo-controlled antidepressant studies in people with depression and dementia. J Am Geriatr Soc 2011;59(4):577-585
36. Gellis Z, McClive-Reed K, Brown E: Treatments for depression in older adults with depression. Ann Long Term Care 2009;17(5):9-10
37. Woods B, Thorgrimsen L, Spector A, et al: Improved quality of life and cognitive stimulation therapy in dementia. Aging Ment Health 2006;10(3):219-226
38. Hoe J, Hancock G, Livingston G, et al: Quality of life of people with dementia in residential care homes. Br J Psychiatry 2006;188:460-464
39. Gaugler JE, Wall MM, Kane RL, et al: Does caregiver burden mediate the effects of behavioral disturbances on nursing home admission? Am J Geriatr Psychiatry 2011;19(6):497-506
40. Watson LC, Lewis CL, Moore CG, et al: Perceptions of depression among dementia caregivers: findings from the CATIE-AD trial. Int J Geriatr Psychiatry 2011;26(4):397-402
41. Teri L, McCurry SM, Logsdon R, et al: Training community consultants to help family members improve dementia care: a randomized controlled trial. Gerontologist 2005;45(6):802-811
42. Martire LM, Lustig AP, Schulz R, et al: Is it beneficial to involve a family member? A meta-analysis of psychosocial interventions for chronic illness. Health Psychol 2004;23(6):599-611
43. Livingston G, Johnston K, Katona C, et al: Systematic review of psychological approaches to the management of neuropsychiatric symptoms of dementia. Am J Psychiatry 2005;162(11):1996-2021